2QEXE

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 41
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 2qexE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 2qexE01
1M90G 5HL7E 1Q86G 1VQLE 3CC4E 2QEXE 4WFAE 1VQ7E 1QVFE 4IOAE 1VQNE 4WF9E 3CCQE 5DM7E 3CCSE 4WFNE 5DM6E 4WCEE 3PIOE 5JVGE 3CD6E 1VQKE 3CMAE 5GAGG 3CCUE 3PIPE 1S72E 3CCME 1VQOE 5JVHE 2ZJQE 3I56E 3OW2E 1YJNE 1KD1G 3G4SE 1N8RG 1VQ9E 4U67E 5H1SI 1YJ9E 3CCEE 3CCVE 3CC2E 1K8AG 1YJWE 1M1KG 4IO9E 5MLCH 3CCRE 3CF5E 1VQ4E 5AN9B 1YITE 1YHQE 3I55E 2ZJRE 1KQSE 3CCJE 1Q81G 3J7ZG 1QVGE 2ZJPE 1VQ8E 1VQ6E 3DLLE 2QA4E 1KC8G 3CXCE 3G71E 3CMEE 4WFBE 1K9MG 1YIJE 1JJ2E 1Q7YG 1RL6A 2CQLA 2OTLE 3CC7E 1W2BE 1K73G 1VQME 1Q82G 1VQ5E 5GADG 1YI2E 3CCLE 3G6EE 1NJIG 3CPWE 5GAEG 1VQPE 4UY8G 2OTJE 5GAHG 4IOCE
chains in the Genus database with same CATH superfamily
1M90G 5HL7E 1Q86G 1RJLC 1VQLE 3AUMO 3CC4E 2QEXE 4WFAE 1FJ1E 1VQ7E 1QVFE 4IOAE 1VQNE 4WF9E 3CCQE 5DM7E 3CCSE 4WFNE 2PI3O 5DM6E 4WCEE 2OYBO 3PIOE 5JVGE 3CD6E 1VQKE 2OL8O 3CMAE 5GAGG 3CCUE 3PIPE 1S72E 3CCME 1VQOE 5JVHE 2ZJQE 3I56E 3OW2E 2G8CO 1YJNE 1KD1G 2OY5O 3G4SE 2OL7A 1N8RG 1VQ9E 4U67E 5B10O 5H1SI 1YJ9E 3CCEE 1OSPO 3CCVE 3CC2E 1K8AG 1YJWE 1M1KG 4IO9E 2OY1O 5MLCH 5B2AO 3CCRE 3CF5E 2OY7A 2FKGA 2OL6O 2HKDA 3CKFA 5AN9B 1VQ4E 1YITE 1YHQE 3IGEA 3I55E 2ZJRE 1KQSE 3CCJE 1Q81G 3J7ZG 5B3MO 1QVGE 2ZJPE 1VQ8E 1VQ6E 3DLLE 3IG9A 2QA4E 1KC8G 3CXCE 2I5ZO 3G71E 2FKJA 3CMEE 4WFBE 1K9MG 2OY8A 1YIJE 5B11O 2AF5A 1JJ2E 1Q7YG 3EC5A 1RL6A 2CQLA 2OTLE 3CC7E 1W2BE 2I5VO 1K73G 1VQME 1Q82G 1P4PA 3CKGA 1VQ5E 5GADG 1YI2E 3CCLE 3G6EE 1NJIG 3CPWE 5GAEG 1VQPE 4UY8G 2OTJE 5GAHG 4IOCE
chains in the Genus database with same CATH topology
1M90G 5HL7E 1Q86G 1VQLE 3CC4E 2QEXE 4WFAE 1VQ7E 1QVFE 4IOAE 1VQNE 4WF9E 3CCQE 5DM7E 3CCSE 4WFNE 5DM6E 4WCEE 3PIOE 5JVGE 3CD6E 1VQKE 3CMAE 5GAGG 3CCUE 3PIPE 1S72E 3CCME 1VQOE 5JVHE 2ZJQE 3I56E 3OW2E 1YJNE 1KD1G 3G4SE 1N8RG 1VQ9E 4U67E 5H1SI 1YJ9E 3CCEE 3CCVE 3CC2E 1K8AG 1YJWE 1M1KG 4IO9E 5MLCH 3CCRE 3CF5E 1VQ4E 5AN9B 1YITE 1YHQE 3I55E 2ZJRE 1KQSE 3CCJE 1Q81G 3J7ZG 1QVGE 2ZJPE 1VQ8E 1VQ6E 3DLLE 2QA4E 1KC8G 3CXCE 3G71E 3CMEE 4WFBE 1K9MG 1YIJE 1JJ2E 1Q7YG 1RL6A 2CQLA 2OTLE 3CC7E 1W2BE 1K73G 1VQME 1Q82G 1VQ5E 5GADG 1YI2E 3CCLE 3G6EE 1NJIG 3CPWE 5GAEG 1VQPE 4UY8G 2OTJE 5GAHG 4IOCE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 G;  5HL7 E;  1Q86 G;  1VQL E;  3CC4 E;  2QEX E;  4WFA E;  1VQ7 E;  1QVF E;  4IOA E;  1VQN E;  4WF9 E;  3CCQ E;  5DM7 E;  3CCS E;  4WFN E;  5DM6 E;  4WCE E;  3PIO E;  5JVG E;  3CD6 E;  1VQK E;  3CMA E;  5GAG G;  3CCU E;  3PIP E;  1S72 E;  3CCM E;  1VQO E;  5JVH E;  2ZJQ E;  3I56 E;  3OW2 E;  1YJN E;  1KD1 G;  3G4S E;  1N8R G;  1VQ9 E;  4U67 E;  5H1S I;  1YJ9 E;  3CCE E;  3CCV E;  3CC2 E;  1K8A G;  1YJW E;  1M1K G;  4IO9 E;  5MLC H;  3CCR E;  3CF5 E;  1VQ4 E;  5AN9 B;  1YIT E;  1YHQ E;  3I55 E;  2ZJR E;  1KQS E;  3CCJ E;  1Q81 G;  3J7Z G;  1QVG E;  2ZJP E;  1VQ8 E;  1VQ6 E;  3DLL E;  2QA4 E;  1KC8 G;  3CXC E;  3G71 E;  3CME E;  4WFB E;  1K9M G;  1YIJ E;  1JJ2 E;  1Q7Y G;  1RL6 A;  2CQL A;  2OTL E;  3CC7 E;  1W2B E;  1K73 G;  1VQM E;  1Q82 G;  1VQ5 E;  5GAD G;  1YI2 E;  3CCL E;  3G6E E;  1NJI G;  3CPW E;  5GAE G;  1VQP E;  4UY8 G;  2OTJ E;  5GAH G;  4IOC E; 
#chains in the Genus database with same CATH topology
 1M90 G;  5HL7 E;  1Q86 G;  1RJL C;  1VQL E;  3AUM O;  3CC4 E;  2QEX E;  4WFA E;  1FJ1 E;  1VQ7 E;  1QVF E;  4IOA E;  1VQN E;  4WF9 E;  3CCQ E;  5DM7 E;  3CCS E;  4WFN E;  2PI3 O;  5DM6 E;  4WCE E;  2OYB O;  3PIO E;  5JVG E;  3CD6 E;  1VQK E;  2OL8 O;  3CMA E;  5GAG G;  3CCU E;  3PIP E;  1S72 E;  3CCM E;  1VQO E;  5JVH E;  2ZJQ E;  3I56 E;  3OW2 E;  2G8C O;  1YJN E;  1KD1 G;  2OY5 O;  3G4S E;  2OL7 A;  1N8R G;  1VQ9 E;  4U67 E;  5B10 O;  5H1S I;  1YJ9 E;  3CCE E;  1OSP O;  3CCV E;  3CC2 E;  1K8A G;  1YJW E;  1M1K G;  4IO9 E;  2OY1 O;  5MLC H;  5B2A O;  3CCR E;  3CF5 E;  2OY7 A;  2FKG A;  2OL6 O;  2HKD A;  3CKF A;  5AN9 B;  1VQ4 E;  1YIT E;  1YHQ E;  3IGE A;  3I55 E;  2ZJR E;  1KQS E;  3CCJ E;  1Q81 G;  3J7Z G;  5B3M O;  1QVG E;  2ZJP E;  1VQ8 E;  1VQ6 E;  3DLL E;  3IG9 A;  2QA4 E;  1KC8 G;  3CXC E;  2I5Z O;  3G71 E;  2FKJ A;  3CME E;  4WFB E;  1K9M G;  2OY8 A;  1YIJ E;  5B11 O;  2AF5 A;  1JJ2 E;  1Q7Y G;  3EC5 A;  1RL6 A;  2CQL A;  2OTL E;  3CC7 E;  1W2B E;  2I5V O;  1K73 G;  1VQM E;  1Q82 G;  1P4P A;  3CKG A;  1VQ5 E;  5GAD G;  1YI2 E;  3CCL E;  3G6E E;  1NJI G;  3CPW E;  5GAE G;  1VQP E;  4UY8 G;  2OTJ E;  5GAH G;  4IOC E; 
#chains in the Genus database with same CATH homology
 1M90 G;  5HL7 E;  1Q86 G;  1VQL E;  3CC4 E;  2QEX E;  4WFA E;  1VQ7 E;  1QVF E;  4IOA E;  1VQN E;  4WF9 E;  3CCQ E;  5DM7 E;  3CCS E;  4WFN E;  5DM6 E;  4WCE E;  3PIO E;  5JVG E;  3CD6 E;  1VQK E;  3CMA E;  5GAG G;  3CCU E;  3PIP E;  1S72 E;  3CCM E;  1VQO E;  5JVH E;  2ZJQ E;  3I56 E;  3OW2 E;  1YJN E;  1KD1 G;  3G4S E;  1N8R G;  1VQ9 E;  4U67 E;  5H1S I;  1YJ9 E;  3CCE E;  3CCV E;  3CC2 E;  1K8A G;  1YJW E;  1M1K G;  4IO9 E;  5MLC H;  3CCR E;  3CF5 E;  1VQ4 E;  5AN9 B;  1YIT E;  1YHQ E;  3I55 E;  2ZJR E;  1KQS E;  3CCJ E;  1Q81 G;  3J7Z G;  1QVG E;  2ZJP E;  1VQ8 E;  1VQ6 E;  3DLL E;  2QA4 E;  1KC8 G;  3CXC E;  3G71 E;  3CME E;  4WFB E;  1K9M G;  1YIJ E;  1JJ2 E;  1Q7Y G;  1RL6 A;  2CQL A;  2OTL E;  3CC7 E;  1W2B E;  1K73 G;  1VQM E;  1Q82 G;  1VQ5 E;  5GAD G;  1YI2 E;  3CCL E;  3G6E E;  1NJI G;  3CPW E;  5GAE G;  1VQP E;  4UY8 G;  2OTJ E;  5GAH G;  4IOC E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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