2QEXE

Negamycin binds to the wall of the nascent chain exit tunnel of the 50s ribosomal subunit
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 41
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 2qexE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 2qexE01
1N8RG 1VQ8E 2CQLA 3CXCE 5HL7E 3CCEE 3CCQE 1Q82G 3J7ZG 2ZJRE 3CCME 5GADG 1W2BE 3CF5E 5AN9B 5JVGE 1NJIG 3CC7E 1VQLE 2OTJE 3CCVE 5H1SI 4WCEE 4IOCE 3CCJE 1JJ2E 1VQ9E 1Q81G 1YJWE 5MLCH 1QVFE 1K73G 2ZJPE 3I55E 5DM7E 3CPWE 1VQME 3CC2E 1VQ7E 1YI2E 5GAEG 1YHQE 1YITE 3I56E 4WFNE 1VQ6E 3CCSE 1VQNE 1M90G 4IOAE 1VQPE 3CMEE 1VQOE 5GAHG 1K9MG 3PIOE 5DM6E 4WFAE 1YJ9E 1VQ4E 1Q86G 3G4SE 1K8AG 1KD1G 1M1KG 3G71E 4IO9E 4UY8G 2QA4E 1KC8G 3CMAE 3CCUE 3OW2E 2OTLE 3G6EE 4WFBE 3CD6E 4WF9E 2QEXE 2ZJQE 1VQ5E 1VQKE 4U67E 5JVHE 1YIJE 5GAGG 3CCLE 1KQSE 3DLLE 1RL6A 1YJNE 3PIPE 1QVGE 3CC4E 3CCRE 1Q7YG 1S72E
chains in the Genus database with same CATH superfamily
1N8RG 1VQ8E 2CQLA 3CXCE 5HL7E 3CCEE 3CCQE 2G8CO 1Q82G 2OL8O 5B3MO 3J7ZG 2ZJRE 3CCME 2OY1O 5GADG 5B11O 1W2BE 3CF5E 1RJLC 5AN9B 2I5ZO 5JVGE 1NJIG 3CC7E 2OY5O 1VQLE 2OTJE 5B2AO 3CCVE 5H1SI 4WCEE 4IOCE 3CCJE 1JJ2E 1VQ9E 1Q81G 2OL6O 1YJWE 5MLCH 1OSPO 1QVFE 3IG9A 1K73G 2ZJPE 3I55E 5DM7E 3CPWE 1VQME 3CC2E 5B10O 1VQ7E 1YI2E 5GAEG 1P4PA 1YHQE 2AF5A 1YITE 3I56E 4WFNE 1VQ6E 3CCSE 1VQNE 1M90G 1FJ1E 4IOAE 1VQPE 3CMEE 1VQOE 5GAHG 1K9MG 3PIOE 3EC5A 5DM6E 4WFAE 2PI3O 1YJ9E 1VQ4E 2HKDA 1Q86G 2OL7A 3G4SE 1K8AG 1KD1G 1M1KG 3G71E 2I5VO 4IO9E 4UY8G 3CKFA 2QA4E 1KC8G 2FKJA 3CMAE 3CCUE 3OW2E 3IGEA 3CKGA 2OTLE 3G6EE 4WFBE 3CD6E 4WF9E 2QEXE 2ZJQE 3AUMO 2FKGA 1VQ5E 2OY8A 1VQKE 4U67E 2OY7A 5JVHE 1YIJE 5GAGG 3CCLE 1KQSE 3DLLE 1RL6A 2OYBO 1YJNE 3PIPE 1QVGE 3CC4E 3CCRE 1Q7YG 1S72E
chains in the Genus database with same CATH topology
1N8RG 1VQ8E 2CQLA 3CXCE 5HL7E 3CCEE 3CCQE 1Q82G 3J7ZG 2ZJRE 3CCME 5GADG 1W2BE 3CF5E 5AN9B 5JVGE 1NJIG 3CC7E 1VQLE 2OTJE 3CCVE 5H1SI 4WCEE 4IOCE 3CCJE 1JJ2E 1VQ9E 1Q81G 1YJWE 5MLCH 1QVFE 1K73G 2ZJPE 3I55E 5DM7E 3CPWE 1VQME 3CC2E 1VQ7E 1YI2E 5GAEG 1YHQE 1YITE 3I56E 4WFNE 1VQ6E 3CCSE 1VQNE 1M90G 4IOAE 1VQPE 3CMEE 1VQOE 5GAHG 1K9MG 3PIOE 5DM6E 4WFAE 1YJ9E 1VQ4E 1Q86G 3G4SE 1K8AG 1KD1G 1M1KG 3G71E 4IO9E 4UY8G 2QA4E 1KC8G 3CMAE 3CCUE 3OW2E 2OTLE 3G6EE 4WFBE 3CD6E 4WF9E 2QEXE 2ZJQE 1VQ5E 1VQKE 4U67E 5JVHE 1YIJE 5GAGG 3CCLE 1KQSE 3DLLE 1RL6A 1YJNE 3PIPE 1QVGE 3CC4E 3CCRE 1Q7YG 1S72E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N8R G;  1VQ8 E;  2CQL A;  3CXC E;  5HL7 E;  3CCE E;  3CCQ E;  1Q82 G;  3J7Z G;  2ZJR E;  3CCM E;  5GAD G;  1W2B E;  3CF5 E;  5AN9 B;  5JVG E;  1NJI G;  3CC7 E;  1VQL E;  2OTJ E;  3CCV E;  5H1S I;  4WCE E;  4IOC E;  3CCJ E;  1JJ2 E;  1VQ9 E;  1Q81 G;  1YJW E;  5MLC H;  1QVF E;  1K73 G;  2ZJP E;  3I55 E;  5DM7 E;  3CPW E;  1VQM E;  3CC2 E;  1VQ7 E;  1YI2 E;  5GAE G;  1YHQ E;  1YIT E;  3I56 E;  4WFN E;  1VQ6 E;  3CCS E;  1VQN E;  1M90 G;  4IOA E;  1VQP E;  3CME E;  1VQO E;  5GAH G;  1K9M G;  3PIO E;  5DM6 E;  4WFA E;  1YJ9 E;  1VQ4 E;  1Q86 G;  3G4S E;  1K8A G;  1KD1 G;  1M1K G;  3G71 E;  4IO9 E;  4UY8 G;  2QA4 E;  1KC8 G;  3CMA E;  3CCU E;  3OW2 E;  2OTL E;  3G6E E;  4WFB E;  3CD6 E;  4WF9 E;  2QEX E;  2ZJQ E;  1VQ5 E;  1VQK E;  4U67 E;  5JVH E;  1YIJ E;  5GAG G;  3CCL E;  1KQS E;  3DLL E;  1RL6 A;  1YJN E;  3PIP E;  1QVG E;  3CC4 E;  3CCR E;  1Q7Y G;  1S72 E; 
#chains in the Genus database with same CATH topology
 1N8R G;  1VQ8 E;  2CQL A;  3CXC E;  5HL7 E;  3CCE E;  3CCQ E;  2G8C O;  1Q82 G;  2OL8 O;  5B3M O;  3J7Z G;  2ZJR E;  3CCM E;  2OY1 O;  5GAD G;  5B11 O;  1W2B E;  3CF5 E;  1RJL C;  5AN9 B;  2I5Z O;  5JVG E;  1NJI G;  3CC7 E;  2OY5 O;  1VQL E;  2OTJ E;  5B2A O;  3CCV E;  5H1S I;  4WCE E;  4IOC E;  3CCJ E;  1JJ2 E;  1VQ9 E;  1Q81 G;  2OL6 O;  1YJW E;  5MLC H;  1OSP O;  1QVF E;  3IG9 A;  1K73 G;  2ZJP E;  3I55 E;  5DM7 E;  3CPW E;  1VQM E;  3CC2 E;  5B10 O;  1VQ7 E;  1YI2 E;  5GAE G;  1P4P A;  1YHQ E;  2AF5 A;  1YIT E;  3I56 E;  4WFN E;  1VQ6 E;  3CCS E;  1VQN E;  1M90 G;  1FJ1 E;  4IOA E;  1VQP E;  3CME E;  1VQO E;  5GAH G;  1K9M G;  3PIO E;  3EC5 A;  5DM6 E;  4WFA E;  2PI3 O;  1YJ9 E;  1VQ4 E;  2HKD A;  1Q86 G;  2OL7 A;  3G4S E;  1K8A G;  1KD1 G;  1M1K G;  3G71 E;  2I5V O;  4IO9 E;  4UY8 G;  3CKF A;  2QA4 E;  1KC8 G;  2FKJ A;  3CMA E;  3CCU E;  3OW2 E;  3IGE A;  3CKG A;  2OTL E;  3G6E E;  4WFB E;  3CD6 E;  4WF9 E;  2QEX E;  2ZJQ E;  3AUM O;  2FKG A;  1VQ5 E;  2OY8 A;  1VQK E;  4U67 E;  2OY7 A;  5JVH E;  1YIJ E;  5GAG G;  3CCL E;  1KQS E;  3DLL E;  1RL6 A;  2OYB O;  1YJN E;  3PIP E;  1QVG E;  3CC4 E;  3CCR E;  1Q7Y G;  1S72 E; 
#chains in the Genus database with same CATH homology
 1N8R G;  1VQ8 E;  2CQL A;  3CXC E;  5HL7 E;  3CCE E;  3CCQ E;  1Q82 G;  3J7Z G;  2ZJR E;  3CCM E;  5GAD G;  1W2B E;  3CF5 E;  5AN9 B;  5JVG E;  1NJI G;  3CC7 E;  1VQL E;  2OTJ E;  3CCV E;  5H1S I;  4WCE E;  4IOC E;  3CCJ E;  1JJ2 E;  1VQ9 E;  1Q81 G;  1YJW E;  5MLC H;  1QVF E;  1K73 G;  2ZJP E;  3I55 E;  5DM7 E;  3CPW E;  1VQM E;  3CC2 E;  1VQ7 E;  1YI2 E;  5GAE G;  1YHQ E;  1YIT E;  3I56 E;  4WFN E;  1VQ6 E;  3CCS E;  1VQN E;  1M90 G;  4IOA E;  1VQP E;  3CME E;  1VQO E;  5GAH G;  1K9M G;  3PIO E;  5DM6 E;  4WFA E;  1YJ9 E;  1VQ4 E;  1Q86 G;  3G4S E;  1K8A G;  1KD1 G;  1M1K G;  3G71 E;  4IO9 E;  4UY8 G;  2QA4 E;  1KC8 G;  3CMA E;  3CCU E;  3OW2 E;  2OTL E;  3G6E E;  4WFB E;  3CD6 E;  4WF9 E;  2QEX E;  2ZJQ E;  1VQ5 E;  1VQK E;  4U67 E;  5JVH E;  1YIJ E;  5GAG G;  3CCL E;  1KQS E;  3DLL E;  1RL6 A;  1YJN E;  3PIP E;  1QVG E;  3CC4 E;  3CCR E;  1Q7Y G;  1S72 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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