3CC4E

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 36
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc4E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc4E01
1VQLE 3CCRE 1VQOE 3G71E 5MLCH 1M1KG 1N8RG 3PIOE 4IO9E 4WCEE 4UY8G 5JVGE 4U67E 1YJNE 1YHQE 3CXCE 1VQ4E 3I56E 1RL6A 5AN9B 1W2BE 3CD6E 1QVFE 1QVGE 1K73G 1VQPE 1K8AG 4WF9E 2OTLE 2ZJPE 3G6EE 1YITE 3CMAE 5H1SI 2QA4E 1VQ7E 1YIJE 3CCSE 3DLLE 1S72E 5DM7E 5GAHG 5GAEG 5GADG 1NJIG 4WFAE 3CC2E 1KC8G 3CCQE 3CCVE 2ZJRE 4WFNE 1VQ9E 4IOCE 5DM6E 2QEXE 5GAGG 4IOAE 3PIPE 3CC4E 3CC7E 1VQ5E 1VQKE 5HL7E 1K9MG 3CCLE 3G4SE 1Q81G 3CPWE 1Q82G 1YI2E 4WFBE 3J7ZG 2OTJE 3CMEE 1Q86G 1KD1G 3CCEE 3OW2E 1YJ9E 2ZJQE 3I55E 3CCUE 2CQLA 1VQ6E 1VQNE 3CCJE 1YJWE 1VQME 1Q7YG 1VQ8E 1JJ2E 5JVHE 3CCME 1M90G 1KQSE 3CF5E
chains in the Genus database with same CATH superfamily
2PI3O 2AF5A 2OY8A 1VQLE 3CCRE 1VQOE 3G71E 5B11O 5MLCH 1M1KG 2FKJA 2OL7A 3EC5A 1N8RG 3PIOE 4IO9E 1FJ1E 4WCEE 4UY8G 5JVGE 4U67E 1YJNE 1YHQE 5B3MO 3CXCE 1VQ4E 3I56E 2FKGA 2OYBO 1RL6A 5AN9B 1W2BE 3CD6E 1QVFE 1K73G 1QVGE 1VQPE 1K8AG 4WF9E 2OTLE 2ZJPE 3G6EE 2OY1O 1YITE 3CKGA 1RJLC 3CMAE 5H1SI 2QA4E 1VQ7E 1YIJE 3CCSE 1OSPO 3DLLE 1S72E 5DM7E 5GAHG 5GAEG 5GADG 1NJIG 4WFAE 3CC2E 5B2AO 1KC8G 3CCQE 3AUMO 3CCVE 2OY5O 3IG9A 2ZJRE 4WFNE 1VQ9E 4IOCE 5DM6E 2QEXE 5GAGG 2I5VO 4IOAE 2G8CO 2HKDA 1P4PA 2I5ZO 3PIPE 3CC4E 3CC7E 1VQ5E 1VQKE 2OL8O 5HL7E 1K9MG 3CCLE 3G4SE 1Q81G 3CPWE 1Q82G 1YI2E 4WFBE 3J7ZG 2OTJE 3CMEE 1Q86G 3IGEA 1KD1G 3CKFA 3CCEE 3OW2E 1YJ9E 2OY7A 2ZJQE 3I55E 3CCUE 2CQLA 1VQ6E 1VQNE 3CCJE 1YJWE 2OL6O 1VQME 1Q7YG 1VQ8E 1JJ2E 5JVHE 3CCME 1M90G 1KQSE 3CF5E 5B10O
chains in the Genus database with same CATH topology
1VQLE 3CCRE 1VQOE 3G71E 5MLCH 1M1KG 1N8RG 3PIOE 4IO9E 4WCEE 4UY8G 5JVGE 4U67E 1YJNE 1YHQE 3CXCE 1VQ4E 3I56E 1RL6A 5AN9B 1W2BE 3CD6E 1QVFE 1QVGE 1K73G 1VQPE 1K8AG 4WF9E 2OTLE 2ZJPE 3G6EE 1YITE 3CMAE 5H1SI 2QA4E 1VQ7E 1YIJE 3CCSE 3DLLE 1S72E 5DM7E 5GAHG 5GAEG 5GADG 1NJIG 4WFAE 3CC2E 1KC8G 3CCQE 3CCVE 2ZJRE 4WFNE 1VQ9E 4IOCE 5DM6E 2QEXE 5GAGG 4IOAE 3PIPE 3CC4E 3CC7E 1VQ5E 1VQKE 5HL7E 1K9MG 3CCLE 3G4SE 1Q81G 3CPWE 1Q82G 1YI2E 4WFBE 3J7ZG 2OTJE 3CMEE 1Q86G 1KD1G 3CCEE 3OW2E 1YJ9E 2ZJQE 3I55E 3CCUE 2CQLA 1VQ6E 1VQNE 3CCJE 1YJWE 1VQME 1Q7YG 1VQ8E 1JJ2E 5JVHE 3CCME 1M90G 1KQSE 3CF5E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQL E;  3CCR E;  1VQO E;  3G71 E;  5MLC H;  1M1K G;  1N8R G;  3PIO E;  4IO9 E;  4WCE E;  4UY8 G;  5JVG E;  4U67 E;  1YJN E;  1YHQ E;  3CXC E;  1VQ4 E;  3I56 E;  1RL6 A;  5AN9 B;  1W2B E;  3CD6 E;  1QVF E;  1QVG E;  1K73 G;  1VQP E;  1K8A G;  4WF9 E;  2OTL E;  2ZJP E;  3G6E E;  1YIT E;  3CMA E;  5H1S I;  2QA4 E;  1VQ7 E;  1YIJ E;  3CCS E;  3DLL E;  1S72 E;  5DM7 E;  5GAH G;  5GAE G;  5GAD G;  1NJI G;  4WFA E;  3CC2 E;  1KC8 G;  3CCQ E;  3CCV E;  2ZJR E;  4WFN E;  1VQ9 E;  4IOC E;  5DM6 E;  2QEX E;  5GAG G;  4IOA E;  3PIP E;  3CC4 E;  3CC7 E;  1VQ5 E;  1VQK E;  5HL7 E;  1K9M G;  3CCL E;  3G4S E;  1Q81 G;  3CPW E;  1Q82 G;  1YI2 E;  4WFB E;  3J7Z G;  2OTJ E;  3CME E;  1Q86 G;  1KD1 G;  3CCE E;  3OW2 E;  1YJ9 E;  2ZJQ E;  3I55 E;  3CCU E;  2CQL A;  1VQ6 E;  1VQN E;  3CCJ E;  1YJW E;  1VQM E;  1Q7Y G;  1VQ8 E;  1JJ2 E;  5JVH E;  3CCM E;  1M90 G;  1KQS E;  3CF5 E; 
#chains in the Genus database with same CATH topology
 2PI3 O;  2AF5 A;  2OY8 A;  1VQL E;  3CCR E;  1VQO E;  3G71 E;  5B11 O;  5MLC H;  1M1K G;  2FKJ A;  2OL7 A;  3EC5 A;  1N8R G;  3PIO E;  4IO9 E;  1FJ1 E;  4WCE E;  4UY8 G;  5JVG E;  4U67 E;  1YJN E;  1YHQ E;  5B3M O;  3CXC E;  1VQ4 E;  3I56 E;  2FKG A;  2OYB O;  1RL6 A;  5AN9 B;  1W2B E;  3CD6 E;  1QVF E;  1K73 G;  1QVG E;  1VQP E;  1K8A G;  4WF9 E;  2OTL E;  2ZJP E;  3G6E E;  2OY1 O;  1YIT E;  3CKG A;  1RJL C;  3CMA E;  5H1S I;  2QA4 E;  1VQ7 E;  1YIJ E;  3CCS E;  1OSP O;  3DLL E;  1S72 E;  5DM7 E;  5GAH G;  5GAE G;  5GAD G;  1NJI G;  4WFA E;  3CC2 E;  5B2A O;  1KC8 G;  3CCQ E;  3AUM O;  3CCV E;  2OY5 O;  3IG9 A;  2ZJR E;  4WFN E;  1VQ9 E;  4IOC E;  5DM6 E;  2QEX E;  5GAG G;  2I5V O;  4IOA E;  2G8C O;  2HKD A;  1P4P A;  2I5Z O;  3PIP E;  3CC4 E;  3CC7 E;  1VQ5 E;  1VQK E;  2OL8 O;  5HL7 E;  1K9M G;  3CCL E;  3G4S E;  1Q81 G;  3CPW E;  1Q82 G;  1YI2 E;  4WFB E;  3J7Z G;  2OTJ E;  3CME E;  1Q86 G;  3IGE A;  1KD1 G;  3CKF A;  3CCE E;  3OW2 E;  1YJ9 E;  2OY7 A;  2ZJQ E;  3I55 E;  3CCU E;  2CQL A;  1VQ6 E;  1VQN E;  3CCJ E;  1YJW E;  2OL6 O;  1VQM E;  1Q7Y G;  1VQ8 E;  1JJ2 E;  5JVH E;  3CCM E;  1M90 G;  1KQS E;  3CF5 E;  5B10 O; 
#chains in the Genus database with same CATH homology
 1VQL E;  3CCR E;  1VQO E;  3G71 E;  5MLC H;  1M1K G;  1N8R G;  3PIO E;  4IO9 E;  4WCE E;  4UY8 G;  5JVG E;  4U67 E;  1YJN E;  1YHQ E;  3CXC E;  1VQ4 E;  3I56 E;  1RL6 A;  5AN9 B;  1W2B E;  3CD6 E;  1QVF E;  1QVG E;  1K73 G;  1VQP E;  1K8A G;  4WF9 E;  2OTL E;  2ZJP E;  3G6E E;  1YIT E;  3CMA E;  5H1S I;  2QA4 E;  1VQ7 E;  1YIJ E;  3CCS E;  3DLL E;  1S72 E;  5DM7 E;  5GAH G;  5GAE G;  5GAD G;  1NJI G;  4WFA E;  3CC2 E;  1KC8 G;  3CCQ E;  3CCV E;  2ZJR E;  4WFN E;  1VQ9 E;  4IOC E;  5DM6 E;  2QEX E;  5GAG G;  4IOA E;  3PIP E;  3CC4 E;  3CC7 E;  1VQ5 E;  1VQK E;  5HL7 E;  1K9M G;  3CCL E;  3G4S E;  1Q81 G;  3CPW E;  1Q82 G;  1YI2 E;  4WFB E;  3J7Z G;  2OTJ E;  3CME E;  1Q86 G;  1KD1 G;  3CCE E;  3OW2 E;  1YJ9 E;  2ZJQ E;  3I55 E;  3CCU E;  2CQL A;  1VQ6 E;  1VQN E;  3CCJ E;  1YJW E;  1VQM E;  1Q7Y G;  1VQ8 E;  1JJ2 E;  5JVH E;  3CCM E;  1M90 G;  1KQS E;  3CF5 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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