3CC4E

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2P
total genus 36
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc4E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc4E01
3CCEE 3CCME 1JJ2E 3CCRE 1VQNE 1YJNE 3CC2E 5HL7E 1KC8G 1VQ9E 1N8RG 4U67E 5JVHE 2ZJQE 1VQOE 3CCJE 4WFAE 1RL6A 3I56E 5AN9B 1S72E 3I55E 1KQSE 1K73G 1YJWE 1W2BE 3CCQE 1VQ7E 2ZJRE 2OTLE 1QVFE 4WFBE 2OTJE 5JVGE 3CCLE 3OW2E 1VQ8E 3PIPE 3CXCE 5H1SI 1QVGE 4IOCE 1VQLE 3DLLE 1YIJE 1Q82G 5DM7E 5GAHG 1NJIG 1M1KG 1VQKE 1K8AG 2QA4E 3G4SE 1M90G 5GAEG 5GAGG 3G71E 4WCEE 2QEXE 1VQ5E 1Q86G 1K9MG 4IOAE 1YI2E 4IO9E 2ZJPE 3CF5E 3CCVE 1YITE 5MLCH 4WF9E 3CC7E 4WFNE 1YJ9E 1YHQE 1Q81G 1KD1G 1VQ6E 3CPWE 1VQPE 3CCSE 3PIOE 1VQ4E 2CQLA 3CD6E 3J7ZG 3CMAE 3CC4E 1Q7YG 1VQME 5GADG 4UY8G 3CMEE 3G6EE 3CCUE 5DM6E
chains in the Genus database with same CATH superfamily
3AUMO 3CCEE 3CCME 1RJLC 3EC5A 1JJ2E 3IGEA 5B11O 2OL6O 3CCRE 1VQNE 1YJNE 5B3MO 3CC2E 5HL7E 1KC8G 2I5ZO 1VQ9E 1N8RG 4U67E 5JVHE 2ZJQE 1VQOE 3CCJE 4WFAE 2AF5A 1RL6A 3I56E 5AN9B 2I5VO 2FKJA 1S72E 3I55E 1KQSE 1K73G 1YJWE 1W2BE 2OL7A 3CCQE 1VQ7E 2ZJRE 2OTLE 1QVFE 4WFBE 2OTJE 5JVGE 3CCLE 3OW2E 1VQ8E 2OY8A 3PIPE 2OY7A 3CXCE 5H1SI 1QVGE 4IOCE 1VQLE 3DLLE 1YIJE 1Q82G 5DM7E 5B2AO 5GAHG 1NJIG 1OSPO 1M1KG 1VQKE 1K8AG 2QA4E 3G4SE 1M90G 3IG9A 5GAEG 5GAGG 3G71E 4WCEE 2QEXE 1VQ5E 2G8CO 1Q86G 1K9MG 4IOAE 1YI2E 3CKFA 4IO9E 2OY1O 2PI3O 1P4PA 2ZJPE 3CF5E 3CCVE 1YITE 5MLCH 4WF9E 3CC7E 2OY5O 5B10O 4WFNE 1YJ9E 1YHQE 1Q81G 1KD1G 1VQ6E 3CPWE 1VQPE 3CCSE 3CKGA 3PIOE 2HKDA 1VQ4E 2OL8O 2CQLA 3CD6E 3J7ZG 3CMAE 3CC4E 2OYBO 1Q7YG 1VQME 2FKGA 5GADG 4UY8G 1FJ1E 3CMEE 3G6EE 3CCUE 5DM6E
chains in the Genus database with same CATH topology
3CCEE 3CCME 1JJ2E 3CCRE 1VQNE 1YJNE 3CC2E 5HL7E 1KC8G 1VQ9E 1N8RG 4U67E 5JVHE 2ZJQE 1VQOE 3CCJE 4WFAE 1RL6A 3I56E 5AN9B 1S72E 3I55E 1KQSE 1K73G 1YJWE 1W2BE 3CCQE 1VQ7E 2ZJRE 2OTLE 1QVFE 4WFBE 2OTJE 5JVGE 3CCLE 3OW2E 1VQ8E 3PIPE 3CXCE 5H1SI 1QVGE 4IOCE 1VQLE 3DLLE 1YIJE 1Q82G 5DM7E 5GAHG 1NJIG 1M1KG 1VQKE 1K8AG 2QA4E 3G4SE 1M90G 5GAEG 5GAGG 3G71E 4WCEE 2QEXE 1VQ5E 1Q86G 1K9MG 4IOAE 1YI2E 4IO9E 2ZJPE 3CF5E 3CCVE 1YITE 5MLCH 4WF9E 3CC7E 4WFNE 1YJ9E 1YHQE 1Q81G 1KD1G 1VQ6E 3CPWE 1VQPE 3CCSE 3PIOE 1VQ4E 2CQLA 3CD6E 3J7ZG 3CMAE 3CC4E 1Q7YG 1VQME 5GADG 4UY8G 3CMEE 3G6EE 3CCUE 5DM6E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCE E;  3CCM E;  1JJ2 E;  3CCR E;  1VQN E;  1YJN E;  3CC2 E;  5HL7 E;  1KC8 G;  1VQ9 E;  1N8R G;  4U67 E;  5JVH E;  2ZJQ E;  1VQO E;  3CCJ E;  4WFA E;  1RL6 A;  3I56 E;  5AN9 B;  1S72 E;  3I55 E;  1KQS E;  1K73 G;  1YJW E;  1W2B E;  3CCQ E;  1VQ7 E;  2ZJR E;  2OTL E;  1QVF E;  4WFB E;  2OTJ E;  5JVG E;  3CCL E;  3OW2 E;  1VQ8 E;  3PIP E;  3CXC E;  5H1S I;  1QVG E;  4IOC E;  1VQL E;  3DLL E;  1YIJ E;  1Q82 G;  5DM7 E;  5GAH G;  1NJI G;  1M1K G;  1VQK E;  1K8A G;  2QA4 E;  3G4S E;  1M90 G;  5GAE G;  5GAG G;  3G71 E;  4WCE E;  2QEX E;  1VQ5 E;  1Q86 G;  1K9M G;  4IOA E;  1YI2 E;  4IO9 E;  2ZJP E;  3CF5 E;  3CCV E;  1YIT E;  5MLC H;  4WF9 E;  3CC7 E;  4WFN E;  1YJ9 E;  1YHQ E;  1Q81 G;  1KD1 G;  1VQ6 E;  3CPW E;  1VQP E;  3CCS E;  3PIO E;  1VQ4 E;  2CQL A;  3CD6 E;  3J7Z G;  3CMA E;  3CC4 E;  1Q7Y G;  1VQM E;  5GAD G;  4UY8 G;  3CME E;  3G6E E;  3CCU E;  5DM6 E; 
#chains in the Genus database with same CATH topology
 3AUM O;  3CCE E;  3CCM E;  1RJL C;  3EC5 A;  1JJ2 E;  3IGE A;  5B11 O;  2OL6 O;  3CCR E;  1VQN E;  1YJN E;  5B3M O;  3CC2 E;  5HL7 E;  1KC8 G;  2I5Z O;  1VQ9 E;  1N8R G;  4U67 E;  5JVH E;  2ZJQ E;  1VQO E;  3CCJ E;  4WFA E;  2AF5 A;  1RL6 A;  3I56 E;  5AN9 B;  2I5V O;  2FKJ A;  1S72 E;  3I55 E;  1KQS E;  1K73 G;  1YJW E;  1W2B E;  2OL7 A;  3CCQ E;  1VQ7 E;  2ZJR E;  2OTL E;  1QVF E;  4WFB E;  2OTJ E;  5JVG E;  3CCL E;  3OW2 E;  1VQ8 E;  2OY8 A;  3PIP E;  2OY7 A;  3CXC E;  5H1S I;  1QVG E;  4IOC E;  1VQL E;  3DLL E;  1YIJ E;  1Q82 G;  5DM7 E;  5B2A O;  5GAH G;  1NJI G;  1OSP O;  1M1K G;  1VQK E;  1K8A G;  2QA4 E;  3G4S E;  1M90 G;  3IG9 A;  5GAE G;  5GAG G;  3G71 E;  4WCE E;  2QEX E;  1VQ5 E;  2G8C O;  1Q86 G;  1K9M G;  4IOA E;  1YI2 E;  3CKF A;  4IO9 E;  2OY1 O;  2PI3 O;  1P4P A;  2ZJP E;  3CF5 E;  3CCV E;  1YIT E;  5MLC H;  4WF9 E;  3CC7 E;  2OY5 O;  5B10 O;  4WFN E;  1YJ9 E;  1YHQ E;  1Q81 G;  1KD1 G;  1VQ6 E;  3CPW E;  1VQP E;  3CCS E;  3CKG A;  3PIO E;  2HKD A;  1VQ4 E;  2OL8 O;  2CQL A;  3CD6 E;  3J7Z G;  3CMA E;  3CC4 E;  2OYB O;  1Q7Y G;  1VQM E;  2FKG A;  5GAD G;  4UY8 G;  1FJ1 E;  3CME E;  3G6E E;  3CCU E;  5DM6 E; 
#chains in the Genus database with same CATH homology
 3CCE E;  3CCM E;  1JJ2 E;  3CCR E;  1VQN E;  1YJN E;  3CC2 E;  5HL7 E;  1KC8 G;  1VQ9 E;  1N8R G;  4U67 E;  5JVH E;  2ZJQ E;  1VQO E;  3CCJ E;  4WFA E;  1RL6 A;  3I56 E;  5AN9 B;  1S72 E;  3I55 E;  1KQS E;  1K73 G;  1YJW E;  1W2B E;  3CCQ E;  1VQ7 E;  2ZJR E;  2OTL E;  1QVF E;  4WFB E;  2OTJ E;  5JVG E;  3CCL E;  3OW2 E;  1VQ8 E;  3PIP E;  3CXC E;  5H1S I;  1QVG E;  4IOC E;  1VQL E;  3DLL E;  1YIJ E;  1Q82 G;  5DM7 E;  5GAH G;  1NJI G;  1M1K G;  1VQK E;  1K8A G;  2QA4 E;  3G4S E;  1M90 G;  5GAE G;  5GAG G;  3G71 E;  4WCE E;  2QEX E;  1VQ5 E;  1Q86 G;  1K9M G;  4IOA E;  1YI2 E;  4IO9 E;  2ZJP E;  3CF5 E;  3CCV E;  1YIT E;  5MLC H;  4WF9 E;  3CC7 E;  4WFN E;  1YJ9 E;  1YHQ E;  1Q81 G;  1KD1 G;  1VQ6 E;  3CPW E;  1VQP E;  3CCS E;  3PIO E;  1VQ4 E;  2CQL A;  3CD6 E;  3J7Z G;  3CMA E;  3CC4 E;  1Q7Y G;  1VQM E;  5GAD G;  4UY8 G;  3CME E;  3G6E E;  3CCU E;  5DM6 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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