3CCEE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cceE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cceE01
3CCSE 4UY8G 1VQOE 1K8AG 1Q86G 3CCQE 5AN9B 3CCLE 4U67E 5DM7E 4IOCE 1YJ9E 4WFAE 1NJIG 1YJNE 1M90G 3CPWE 3CD6E 3CXCE 1VQ6E 5JVHE 5GAEG 1VQ5E 2QEXE 2QA4E 1VQKE 1YHQE 2OTJE 3CCEE 1W2BE 1YJWE 4WF9E 1Q7YG 5GADG 3CCJE 3G71E 2ZJPE 1VQ8E 3I56E 5MLCH 1VQME 1VQLE 1YITE 1Q81G 1N8RG 1VQ7E 1KQSE 1VQPE 3PIOE 5GAGG 4WFNE 3CC4E 3CMEE 3OW2E 3CMAE 5H1SI 1K9MG 5GAHG 4WCEE 1QVFE 1VQ4E 1RL6A 1KD1G 5JVGE 3CF5E 3G4SE 2OTLE 4IOAE 1YIJE 3CCUE 2CQLA 2ZJQE 3CC7E 4WFBE 2ZJRE 1JJ2E 3CCME 3DLLE 3CC2E 1VQ9E 5HL7E 3I55E 1S72E 3CCRE 1VQNE 3CCVE 3J7ZG 1M1KG 1K73G 1YI2E 1QVGE 4IO9E 1KC8G 3G6EE 5DM6E 1Q82G 3PIPE
chains in the Genus database with same CATH superfamily
3CCSE 4UY8G 1VQOE 1K8AG 1Q86G 3CCQE 5AN9B 3CCLE 2OY1O 4U67E 1OSPO 2FKGA 5B10O 3IGEA 5DM7E 4IOCE 2G8CO 1YJ9E 4WFAE 1NJIG 1YJNE 1M90G 3CPWE 3CD6E 3CXCE 1VQ6E 5JVHE 5GAEG 1VQ5E 2QEXE 2QA4E 2OL8O 1VQKE 1YHQE 2OTJE 3CCEE 1W2BE 1P4PA 1YJWE 4WF9E 1Q7YG 2OL6O 2OL7A 5GADG 3CCJE 3G71E 2ZJPE 1VQ8E 3I56E 5MLCH 1VQME 3IG9A 1VQLE 2OY7A 2PI3O 1YITE 3CKGA 5B3MO 1Q81G 1N8RG 1VQ7E 1KQSE 1VQPE 3PIOE 5GAGG 3CKFA 4WFNE 1RJLC 3CC4E 3CMEE 3AUMO 3OW2E 3CMAE 5H1SI 1K9MG 5B2AO 5GAHG 2FKJA 2I5ZO 4WCEE 1QVFE 1VQ4E 1RL6A 1KD1G 5JVGE 3CF5E 3G4SE 2OTLE 4IOAE 2OY8A 2I5VO 3CCUE 1FJ1E 1YIJE 2OY5O 2CQLA 2ZJQE 2AF5A 3CC7E 4WFBE 2ZJRE 1JJ2E 3CCME 3EC5A 3DLLE 3CC2E 1VQ9E 5HL7E 3I55E 1S72E 3CCRE 1VQNE 3CCVE 3J7ZG 1M1KG 1K73G 1YI2E 1QVGE 4IO9E 1KC8G 3G6EE 5DM6E 5B11O 2OYBO 2HKDA 1Q82G 3PIPE
chains in the Genus database with same CATH topology
3CCSE 4UY8G 1VQOE 1K8AG 1Q86G 3CCQE 5AN9B 3CCLE 4U67E 5DM7E 4IOCE 1YJ9E 4WFAE 1NJIG 1YJNE 1M90G 3CPWE 3CD6E 3CXCE 1VQ6E 5JVHE 5GAEG 1VQ5E 2QEXE 2QA4E 1VQKE 1YHQE 2OTJE 3CCEE 1W2BE 1YJWE 4WF9E 1Q7YG 5GADG 3CCJE 3G71E 2ZJPE 1VQ8E 3I56E 5MLCH 1VQME 1VQLE 1YITE 1Q81G 1N8RG 1VQ7E 1KQSE 1VQPE 3PIOE 5GAGG 4WFNE 3CC4E 3CMEE 3OW2E 3CMAE 5H1SI 1K9MG 5GAHG 4WCEE 1QVFE 1VQ4E 1RL6A 1KD1G 5JVGE 3CF5E 3G4SE 2OTLE 4IOAE 1YIJE 3CCUE 2CQLA 2ZJQE 3CC7E 4WFBE 2ZJRE 1JJ2E 3CCME 3DLLE 3CC2E 1VQ9E 5HL7E 3I55E 1S72E 3CCRE 1VQNE 3CCVE 3J7ZG 1M1KG 1K73G 1YI2E 1QVGE 4IO9E 1KC8G 3G6EE 5DM6E 1Q82G 3PIPE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCS E;  4UY8 G;  1VQO E;  1K8A G;  1Q86 G;  3CCQ E;  5AN9 B;  3CCL E;  4U67 E;  5DM7 E;  4IOC E;  1YJ9 E;  4WFA E;  1NJI G;  1YJN E;  1M90 G;  3CPW E;  3CD6 E;  3CXC E;  1VQ6 E;  5JVH E;  5GAE G;  1VQ5 E;  2QEX E;  2QA4 E;  1VQK E;  1YHQ E;  2OTJ E;  3CCE E;  1W2B E;  1YJW E;  4WF9 E;  1Q7Y G;  5GAD G;  3CCJ E;  3G71 E;  2ZJP E;  1VQ8 E;  3I56 E;  5MLC H;  1VQM E;  1VQL E;  1YIT E;  1Q81 G;  1N8R G;  1VQ7 E;  1KQS E;  1VQP E;  3PIO E;  5GAG G;  4WFN E;  3CC4 E;  3CME E;  3OW2 E;  3CMA E;  5H1S I;  1K9M G;  5GAH G;  4WCE E;  1QVF E;  1VQ4 E;  1RL6 A;  1KD1 G;  5JVG E;  3CF5 E;  3G4S E;  2OTL E;  4IOA E;  1YIJ E;  3CCU E;  2CQL A;  2ZJQ E;  3CC7 E;  4WFB E;  2ZJR E;  1JJ2 E;  3CCM E;  3DLL E;  3CC2 E;  1VQ9 E;  5HL7 E;  3I55 E;  1S72 E;  3CCR E;  1VQN E;  3CCV E;  3J7Z G;  1M1K G;  1K73 G;  1YI2 E;  1QVG E;  4IO9 E;  1KC8 G;  3G6E E;  5DM6 E;  1Q82 G;  3PIP E; 
#chains in the Genus database with same CATH topology
 3CCS E;  4UY8 G;  1VQO E;  1K8A G;  1Q86 G;  3CCQ E;  5AN9 B;  3CCL E;  2OY1 O;  4U67 E;  1OSP O;  2FKG A;  5B10 O;  3IGE A;  5DM7 E;  4IOC E;  2G8C O;  1YJ9 E;  4WFA E;  1NJI G;  1YJN E;  1M90 G;  3CPW E;  3CD6 E;  3CXC E;  1VQ6 E;  5JVH E;  5GAE G;  1VQ5 E;  2QEX E;  2QA4 E;  2OL8 O;  1VQK E;  1YHQ E;  2OTJ E;  3CCE E;  1W2B E;  1P4P A;  1YJW E;  4WF9 E;  1Q7Y G;  2OL6 O;  2OL7 A;  5GAD G;  3CCJ E;  3G71 E;  2ZJP E;  1VQ8 E;  3I56 E;  5MLC H;  1VQM E;  3IG9 A;  1VQL E;  2OY7 A;  2PI3 O;  1YIT E;  3CKG A;  5B3M O;  1Q81 G;  1N8R G;  1VQ7 E;  1KQS E;  1VQP E;  3PIO E;  5GAG G;  3CKF A;  4WFN E;  1RJL C;  3CC4 E;  3CME E;  3AUM O;  3OW2 E;  3CMA E;  5H1S I;  1K9M G;  5B2A O;  5GAH G;  2FKJ A;  2I5Z O;  4WCE E;  1QVF E;  1VQ4 E;  1RL6 A;  1KD1 G;  5JVG E;  3CF5 E;  3G4S E;  2OTL E;  4IOA E;  2OY8 A;  2I5V O;  3CCU E;  1FJ1 E;  1YIJ E;  2OY5 O;  2CQL A;  2ZJQ E;  2AF5 A;  3CC7 E;  4WFB E;  2ZJR E;  1JJ2 E;  3CCM E;  3EC5 A;  3DLL E;  3CC2 E;  1VQ9 E;  5HL7 E;  3I55 E;  1S72 E;  3CCR E;  1VQN E;  3CCV E;  3J7Z G;  1M1K G;  1K73 G;  1YI2 E;  1QVG E;  4IO9 E;  1KC8 G;  3G6E E;  5DM6 E;  5B11 O;  2OYB O;  2HKD A;  1Q82 G;  3PIP E; 
#chains in the Genus database with same CATH homology
 3CCS E;  4UY8 G;  1VQO E;  1K8A G;  1Q86 G;  3CCQ E;  5AN9 B;  3CCL E;  4U67 E;  5DM7 E;  4IOC E;  1YJ9 E;  4WFA E;  1NJI G;  1YJN E;  1M90 G;  3CPW E;  3CD6 E;  3CXC E;  1VQ6 E;  5JVH E;  5GAE G;  1VQ5 E;  2QEX E;  2QA4 E;  1VQK E;  1YHQ E;  2OTJ E;  3CCE E;  1W2B E;  1YJW E;  4WF9 E;  1Q7Y G;  5GAD G;  3CCJ E;  3G71 E;  2ZJP E;  1VQ8 E;  3I56 E;  5MLC H;  1VQM E;  1VQL E;  1YIT E;  1Q81 G;  1N8R G;  1VQ7 E;  1KQS E;  1VQP E;  3PIO E;  5GAG G;  4WFN E;  3CC4 E;  3CME E;  3OW2 E;  3CMA E;  5H1S I;  1K9M G;  5GAH G;  4WCE E;  1QVF E;  1VQ4 E;  1RL6 A;  1KD1 G;  5JVG E;  3CF5 E;  3G4S E;  2OTL E;  4IOA E;  1YIJ E;  3CCU E;  2CQL A;  2ZJQ E;  3CC7 E;  4WFB E;  2ZJR E;  1JJ2 E;  3CCM E;  3DLL E;  3CC2 E;  1VQ9 E;  5HL7 E;  3I55 E;  1S72 E;  3CCR E;  1VQN E;  3CCV E;  3J7Z G;  1M1K G;  1K73 G;  1YI2 E;  1QVG E;  4IO9 E;  1KC8 G;  3G6E E;  5DM6 E;  1Q82 G;  3PIP E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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