3CCEE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cceE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cceE01
2QA4E 1K9MG 3PIPE 3G4SE 1YIJE 3PIOE 3CXCE 1VQLE 1JJ2E 1M1KG 5JVHE 1QVFE 3G71E 1VQ6E 3CCRE 4IOAE 1N8RG 5JVGE 1NJIG 1YITE 3G6EE 4WCEE 1VQPE 4IO9E 1Q82G 3CCUE 3CCEE 4WFNE 4WFAE 3CMAE 3I56E 5GAEG 3CCQE 1K73G 2CQLA 3CPWE 1YJNE 1VQKE 1YJ9E 5GADG 1YI2E 2ZJRE 3OW2E 1KQSE 4WFBE 1K8AG 3DLLE 1KD1G 4UY8G 3CD6E 2QEXE 1M90G 1Q7YG 2ZJPE 5MLCH 5GAGG 1YJWE 1KC8G 1VQ5E 1W2BE 3CCSE 3CCVE 2OTLE 3CC4E 5AN9B 3CF5E 1VQ4E 1Q81G 1QVGE 4U67E 5GAHG 5H1SI 3CCLE 3CCJE 3CC2E 5DM6E 1Q86G 3CCME 3CC7E 3J7ZG 2ZJQE 3I55E 1YHQE 2OTJE 4IOCE 1RL6A 1VQOE 1VQNE 1VQ8E 1VQ9E 1VQME 1S72E 1VQ7E 3CMEE 5HL7E 5DM7E 4WF9E
chains in the Genus database with same CATH superfamily
2QA4E 1K9MG 3PIPE 3G4SE 1YIJE 3AUMO 3PIOE 3CXCE 1VQLE 1JJ2E 1M1KG 2OY8A 5JVHE 5B3MO 1QVFE 3G71E 2OY5O 1FJ1E 1VQ6E 3CCRE 4IOAE 1RJLC 1N8RG 5JVGE 1NJIG 1YITE 2PI3O 3CKGA 3G6EE 4WCEE 2OYBO 4IO9E 1VQPE 1Q82G 3CCUE 3CCEE 4WFNE 4WFAE 3CMAE 2OY1O 3I56E 3EC5A 5GAEG 3CCQE 1K73G 2CQLA 3CPWE 1YJNE 1VQKE 1P4PA 2I5VO 1YJ9E 5GADG 1YI2E 2ZJRE 3OW2E 1KQSE 4WFBE 1K8AG 3DLLE 1KD1G 2AF5A 4UY8G 3CD6E 2QEXE 1M90G 1Q7YG 2ZJPE 5MLCH 2FKGA 5GAGG 1YJWE 1KC8G 1VQ5E 1W2BE 3CCSE 3CCVE 2HKDA 2OL6O 2OTLE 2I5ZO 3CC4E 5AN9B 3CF5E 1VQ4E 1Q81G 1QVGE 4U67E 5GAHG 5H1SI 3CCLE 1OSPO 3CCJE 5B10O 3CC2E 2OL7A 5DM6E 5B11O 1Q86G 2G8CO 3CKFA 3CC7E 3CCME 2OL8O 3J7ZG 2ZJQE 3I55E 5B2AO 1YHQE 2FKJA 2OTJE 4IOCE 1RL6A 2OY7A 1VQOE 1VQNE 1VQ8E 3IGEA 1VQ9E 1VQME 1S72E 1VQ7E 3CMEE 5HL7E 5DM7E 3IG9A 4WF9E
chains in the Genus database with same CATH topology
2QA4E 1K9MG 3PIPE 3G4SE 1YIJE 3PIOE 3CXCE 1VQLE 1JJ2E 1M1KG 5JVHE 1QVFE 3G71E 1VQ6E 3CCRE 4IOAE 1N8RG 5JVGE 1NJIG 1YITE 3G6EE 4WCEE 1VQPE 4IO9E 1Q82G 3CCUE 3CCEE 4WFNE 4WFAE 3CMAE 3I56E 5GAEG 3CCQE 1K73G 2CQLA 3CPWE 1YJNE 1VQKE 1YJ9E 5GADG 1YI2E 2ZJRE 3OW2E 1KQSE 4WFBE 1K8AG 3DLLE 1KD1G 4UY8G 3CD6E 2QEXE 1M90G 1Q7YG 2ZJPE 5MLCH 5GAGG 1YJWE 1KC8G 1VQ5E 1W2BE 3CCSE 3CCVE 2OTLE 3CC4E 5AN9B 3CF5E 1VQ4E 1Q81G 1QVGE 4U67E 5GAHG 5H1SI 3CCLE 3CCJE 3CC2E 5DM6E 1Q86G 3CCME 3CC7E 3J7ZG 2ZJQE 3I55E 1YHQE 2OTJE 4IOCE 1RL6A 1VQOE 1VQNE 1VQ8E 1VQ9E 1VQME 1S72E 1VQ7E 3CMEE 5HL7E 5DM7E 4WF9E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QA4 E;  1K9M G;  3PIP E;  3G4S E;  1YIJ E;  3PIO E;  3CXC E;  1VQL E;  1JJ2 E;  1M1K G;  5JVH E;  1QVF E;  3G71 E;  1VQ6 E;  3CCR E;  4IOA E;  1N8R G;  5JVG E;  1NJI G;  1YIT E;  3G6E E;  4WCE E;  1VQP E;  4IO9 E;  1Q82 G;  3CCU E;  3CCE E;  4WFN E;  4WFA E;  3CMA E;  3I56 E;  5GAE G;  3CCQ E;  1K73 G;  2CQL A;  3CPW E;  1YJN E;  1VQK E;  1YJ9 E;  5GAD G;  1YI2 E;  2ZJR E;  3OW2 E;  1KQS E;  4WFB E;  1K8A G;  3DLL E;  1KD1 G;  4UY8 G;  3CD6 E;  2QEX E;  1M90 G;  1Q7Y G;  2ZJP E;  5MLC H;  5GAG G;  1YJW E;  1KC8 G;  1VQ5 E;  1W2B E;  3CCS E;  3CCV E;  2OTL E;  3CC4 E;  5AN9 B;  3CF5 E;  1VQ4 E;  1Q81 G;  1QVG E;  4U67 E;  5GAH G;  5H1S I;  3CCL E;  3CCJ E;  3CC2 E;  5DM6 E;  1Q86 G;  3CCM E;  3CC7 E;  3J7Z G;  2ZJQ E;  3I55 E;  1YHQ E;  2OTJ E;  4IOC E;  1RL6 A;  1VQO E;  1VQN E;  1VQ8 E;  1VQ9 E;  1VQM E;  1S72 E;  1VQ7 E;  3CME E;  5HL7 E;  5DM7 E;  4WF9 E; 
#chains in the Genus database with same CATH topology
 2QA4 E;  1K9M G;  3PIP E;  3G4S E;  1YIJ E;  3AUM O;  3PIO E;  3CXC E;  1VQL E;  1JJ2 E;  1M1K G;  2OY8 A;  5JVH E;  5B3M O;  1QVF E;  3G71 E;  2OY5 O;  1FJ1 E;  1VQ6 E;  3CCR E;  4IOA E;  1RJL C;  1N8R G;  5JVG E;  1NJI G;  1YIT E;  2PI3 O;  3CKG A;  3G6E E;  4WCE E;  2OYB O;  4IO9 E;  1VQP E;  1Q82 G;  3CCU E;  3CCE E;  4WFN E;  4WFA E;  3CMA E;  2OY1 O;  3I56 E;  3EC5 A;  5GAE G;  3CCQ E;  1K73 G;  2CQL A;  3CPW E;  1YJN E;  1VQK E;  1P4P A;  2I5V O;  1YJ9 E;  5GAD G;  1YI2 E;  2ZJR E;  3OW2 E;  1KQS E;  4WFB E;  1K8A G;  3DLL E;  1KD1 G;  2AF5 A;  4UY8 G;  3CD6 E;  2QEX E;  1M90 G;  1Q7Y G;  2ZJP E;  5MLC H;  2FKG A;  5GAG G;  1YJW E;  1KC8 G;  1VQ5 E;  1W2B E;  3CCS E;  3CCV E;  2HKD A;  2OL6 O;  2OTL E;  2I5Z O;  3CC4 E;  5AN9 B;  3CF5 E;  1VQ4 E;  1Q81 G;  1QVG E;  4U67 E;  5GAH G;  5H1S I;  3CCL E;  1OSP O;  3CCJ E;  5B10 O;  3CC2 E;  2OL7 A;  5DM6 E;  5B11 O;  1Q86 G;  2G8C O;  3CKF A;  3CC7 E;  3CCM E;  2OL8 O;  3J7Z G;  2ZJQ E;  3I55 E;  5B2A O;  1YHQ E;  2FKJ A;  2OTJ E;  4IOC E;  1RL6 A;  2OY7 A;  1VQO E;  1VQN E;  1VQ8 E;  3IGE A;  1VQ9 E;  1VQM E;  1S72 E;  1VQ7 E;  3CME E;  5HL7 E;  5DM7 E;  3IG9 A;  4WF9 E; 
#chains in the Genus database with same CATH homology
 2QA4 E;  1K9M G;  3PIP E;  3G4S E;  1YIJ E;  3PIO E;  3CXC E;  1VQL E;  1JJ2 E;  1M1K G;  5JVH E;  1QVF E;  3G71 E;  1VQ6 E;  3CCR E;  4IOA E;  1N8R G;  5JVG E;  1NJI G;  1YIT E;  3G6E E;  4WCE E;  1VQP E;  4IO9 E;  1Q82 G;  3CCU E;  3CCE E;  4WFN E;  4WFA E;  3CMA E;  3I56 E;  5GAE G;  3CCQ E;  1K73 G;  2CQL A;  3CPW E;  1YJN E;  1VQK E;  1YJ9 E;  5GAD G;  1YI2 E;  2ZJR E;  3OW2 E;  1KQS E;  4WFB E;  1K8A G;  3DLL E;  1KD1 G;  4UY8 G;  3CD6 E;  2QEX E;  1M90 G;  1Q7Y G;  2ZJP E;  5MLC H;  5GAG G;  1YJW E;  1KC8 G;  1VQ5 E;  1W2B E;  3CCS E;  3CCV E;  2OTL E;  3CC4 E;  5AN9 B;  3CF5 E;  1VQ4 E;  1Q81 G;  1QVG E;  4U67 E;  5GAH G;  5H1S I;  3CCL E;  3CCJ E;  3CC2 E;  5DM6 E;  1Q86 G;  3CCM E;  3CC7 E;  3J7Z G;  2ZJQ E;  3I55 E;  1YHQ E;  2OTJ E;  4IOC E;  1RL6 A;  1VQO E;  1VQN E;  1VQ8 E;  1VQ9 E;  1VQM E;  1S72 E;  1VQ7 E;  3CME E;  5HL7 E;  5DM7 E;  4WF9 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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