3CCJE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccjE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccjE01
5JVGE 3CCEE 1M90G 3CMAE 1VQ4E 1YIJE 2OTLE 1QVFE 1VQ7E 1YHQE 1RL6A 2ZJQE 2OTJE 3OW2E 1Q81G 3G71E 5GADG 5H1SI 2ZJPE 3G4SE 4WFNE 5AN9B 3I56E 1KD1G 4IO9E 5GAHG 4IOCE 3I55E 1YJWE 1Q82G 1VQKE 3CMEE 1YJNE 1JJ2E 1YI2E 1K73G 3CCUE 3CF5E 3CPWE 4U67E 1K8AG 1VQPE 1VQME 3CD6E 5MLCH 1NJIG 2QEXE 4WFBE 3CCRE 1VQ6E 3CCME 1QVGE 5DM6E 1N8RG 1M1KG 4IOAE 4WFAE 1KQSE 1S72E 4WCEE 1Q7YG 3CXCE 1VQLE 3PIPE 3PIOE 1YJ9E 1YITE 3CC4E 1KC8G 1K9MG 1VQOE 2CQLA 1VQ5E 3CCLE 2QA4E 1VQNE 3CCJE 3DLLE 3G6EE 3CCVE 2ZJRE 4UY8G 5DM7E 1Q86G 1VQ8E 1W2BE 1VQ9E 3CCQE 4WF9E 3CCSE 5GAEG 3CC7E 3CC2E 5JVHE 5GAGG 5HL7E 3J7ZG
chains in the Genus database with same CATH superfamily
5B3MO 3EC5A 2AF5A 5JVGE 5B2AO 3IGEA 3CCEE 1M90G 3CMAE 1VQ4E 1YIJE 3AUMO 2OTLE 1VQ7E 1QVFE 1YHQE 1RL6A 2ZJQE 2OYBO 2OTJE 3OW2E 1Q81G 3G71E 5GADG 5H1SI 2ZJPE 3G4SE 4WFNE 5AN9B 3I56E 1KD1G 4IO9E 5GAHG 4IOCE 2OY7A 1OSPO 3I55E 1YJWE 1Q82G 1VQKE 2FKGA 3CMEE 1P4PA 1YJNE 1JJ2E 1YI2E 1K73G 3CCUE 3CF5E 3IG9A 3CPWE 4U67E 1K8AG 1VQPE 1VQME 3CD6E 5MLCH 1NJIG 2QEXE 4WFBE 3CCRE 1VQ6E 3CCME 1QVGE 5DM6E 1N8RG 1M1KG 4IOAE 4WFAE 1KQSE 1S72E 4WCEE 3CKGA 1Q7YG 2OL6O 3CXCE 1VQLE 3PIPE 3CKFA 3PIOE 2I5ZO 2G8CO 1YJ9E 1RJLC 3CC4E 1YITE 1KC8G 2FKJA 1K9MG 1VQOE 2CQLA 1VQ5E 3CCLE 2OY5O 2QA4E 1VQNE 3CCJE 3DLLE 3G6EE 1FJ1E 3CCVE 2ZJRE 4UY8G 2I5VO 2OY8A 5DM7E 2OL7A 2PI3O 5B10O 1Q86G 1VQ8E 2OL8O 1W2BE 2OY1O 1VQ9E 3CCQE 4WF9E 3CCSE 5GAEG 3CC7E 3CC2E 5JVHE 5B11O 5GAGG 5HL7E 3J7ZG 2HKDA
chains in the Genus database with same CATH topology
5JVGE 3CCEE 1M90G 3CMAE 1VQ4E 1YIJE 2OTLE 1QVFE 1VQ7E 1YHQE 1RL6A 2ZJQE 2OTJE 3OW2E 1Q81G 3G71E 5GADG 5H1SI 2ZJPE 3G4SE 4WFNE 5AN9B 3I56E 1KD1G 4IO9E 5GAHG 4IOCE 3I55E 1YJWE 1Q82G 1VQKE 3CMEE 1YJNE 1JJ2E 1YI2E 1K73G 3CCUE 3CF5E 3CPWE 4U67E 1K8AG 1VQPE 1VQME 3CD6E 5MLCH 1NJIG 2QEXE 4WFBE 3CCRE 1VQ6E 3CCME 1QVGE 5DM6E 1N8RG 1M1KG 4IOAE 4WFAE 1KQSE 1S72E 4WCEE 1Q7YG 3CXCE 1VQLE 3PIPE 3PIOE 1YJ9E 1YITE 3CC4E 1KC8G 1K9MG 1VQOE 2CQLA 1VQ5E 3CCLE 2QA4E 1VQNE 3CCJE 3DLLE 3G6EE 3CCVE 2ZJRE 4UY8G 5DM7E 1Q86G 1VQ8E 1W2BE 1VQ9E 3CCQE 4WF9E 3CCSE 5GAEG 3CC7E 3CC2E 5JVHE 5GAGG 5HL7E 3J7ZG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVG E;  3CCE E;  1M90 G;  3CMA E;  1VQ4 E;  1YIJ E;  2OTL E;  1QVF E;  1VQ7 E;  1YHQ E;  1RL6 A;  2ZJQ E;  2OTJ E;  3OW2 E;  1Q81 G;  3G71 E;  5GAD G;  5H1S I;  2ZJP E;  3G4S E;  4WFN E;  5AN9 B;  3I56 E;  1KD1 G;  4IO9 E;  5GAH G;  4IOC E;  3I55 E;  1YJW E;  1Q82 G;  1VQK E;  3CME E;  1YJN E;  1JJ2 E;  1YI2 E;  1K73 G;  3CCU E;  3CF5 E;  3CPW E;  4U67 E;  1K8A G;  1VQP E;  1VQM E;  3CD6 E;  5MLC H;  1NJI G;  2QEX E;  4WFB E;  3CCR E;  1VQ6 E;  3CCM E;  1QVG E;  5DM6 E;  1N8R G;  1M1K G;  4IOA E;  4WFA E;  1KQS E;  1S72 E;  4WCE E;  1Q7Y G;  3CXC E;  1VQL E;  3PIP E;  3PIO E;  1YJ9 E;  1YIT E;  3CC4 E;  1KC8 G;  1K9M G;  1VQO E;  2CQL A;  1VQ5 E;  3CCL E;  2QA4 E;  1VQN E;  3CCJ E;  3DLL E;  3G6E E;  3CCV E;  2ZJR E;  4UY8 G;  5DM7 E;  1Q86 G;  1VQ8 E;  1W2B E;  1VQ9 E;  3CCQ E;  4WF9 E;  3CCS E;  5GAE G;  3CC7 E;  3CC2 E;  5JVH E;  5GAG G;  5HL7 E;  3J7Z G; 
#chains in the Genus database with same CATH topology
 5B3M O;  3EC5 A;  2AF5 A;  5JVG E;  5B2A O;  3IGE A;  3CCE E;  1M90 G;  3CMA E;  1VQ4 E;  1YIJ E;  3AUM O;  2OTL E;  1VQ7 E;  1QVF E;  1YHQ E;  1RL6 A;  2ZJQ E;  2OYB O;  2OTJ E;  3OW2 E;  1Q81 G;  3G71 E;  5GAD G;  5H1S I;  2ZJP E;  3G4S E;  4WFN E;  5AN9 B;  3I56 E;  1KD1 G;  4IO9 E;  5GAH G;  4IOC E;  2OY7 A;  1OSP O;  3I55 E;  1YJW E;  1Q82 G;  1VQK E;  2FKG A;  3CME E;  1P4P A;  1YJN E;  1JJ2 E;  1YI2 E;  1K73 G;  3CCU E;  3CF5 E;  3IG9 A;  3CPW E;  4U67 E;  1K8A G;  1VQP E;  1VQM E;  3CD6 E;  5MLC H;  1NJI G;  2QEX E;  4WFB E;  3CCR E;  1VQ6 E;  3CCM E;  1QVG E;  5DM6 E;  1N8R G;  1M1K G;  4IOA E;  4WFA E;  1KQS E;  1S72 E;  4WCE E;  3CKG A;  1Q7Y G;  2OL6 O;  3CXC E;  1VQL E;  3PIP E;  3CKF A;  3PIO E;  2I5Z O;  2G8C O;  1YJ9 E;  1RJL C;  3CC4 E;  1YIT E;  1KC8 G;  2FKJ A;  1K9M G;  1VQO E;  2CQL A;  1VQ5 E;  3CCL E;  2OY5 O;  2QA4 E;  1VQN E;  3CCJ E;  3DLL E;  3G6E E;  1FJ1 E;  3CCV E;  2ZJR E;  4UY8 G;  2I5V O;  2OY8 A;  5DM7 E;  2OL7 A;  2PI3 O;  5B10 O;  1Q86 G;  1VQ8 E;  2OL8 O;  1W2B E;  2OY1 O;  1VQ9 E;  3CCQ E;  4WF9 E;  3CCS E;  5GAE G;  3CC7 E;  3CC2 E;  5JVH E;  5B11 O;  5GAG G;  5HL7 E;  3J7Z G;  2HKD A; 
#chains in the Genus database with same CATH homology
 5JVG E;  3CCE E;  1M90 G;  3CMA E;  1VQ4 E;  1YIJ E;  2OTL E;  1QVF E;  1VQ7 E;  1YHQ E;  1RL6 A;  2ZJQ E;  2OTJ E;  3OW2 E;  1Q81 G;  3G71 E;  5GAD G;  5H1S I;  2ZJP E;  3G4S E;  4WFN E;  5AN9 B;  3I56 E;  1KD1 G;  4IO9 E;  5GAH G;  4IOC E;  3I55 E;  1YJW E;  1Q82 G;  1VQK E;  3CME E;  1YJN E;  1JJ2 E;  1YI2 E;  1K73 G;  3CCU E;  3CF5 E;  3CPW E;  4U67 E;  1K8A G;  1VQP E;  1VQM E;  3CD6 E;  5MLC H;  1NJI G;  2QEX E;  4WFB E;  3CCR E;  1VQ6 E;  3CCM E;  1QVG E;  5DM6 E;  1N8R G;  1M1K G;  4IOA E;  4WFA E;  1KQS E;  1S72 E;  4WCE E;  1Q7Y G;  3CXC E;  1VQL E;  3PIP E;  3PIO E;  1YJ9 E;  1YIT E;  3CC4 E;  1KC8 G;  1K9M G;  1VQO E;  2CQL A;  1VQ5 E;  3CCL E;  2QA4 E;  1VQN E;  3CCJ E;  3DLL E;  3G6E E;  3CCV E;  2ZJR E;  4UY8 G;  5DM7 E;  1Q86 G;  1VQ8 E;  1W2B E;  1VQ9 E;  3CCQ E;  4WF9 E;  3CCS E;  5GAE G;  3CC7 E;  3CC2 E;  5JVH E;  5GAG G;  5HL7 E;  3J7Z G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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