3CCME

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccmE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccmE01
1Q86G 5DM7E 1VQ8E 3CD6E 5HL7E 1S72E 3CC2E 1W2BE 1VQNE 5GAEG 1YHQE 1N8RG 2OTLE 2ZJRE 3CCVE 3CCLE 3CMAE 1QVFE 3CCEE 5JVHE 3G71E 1Q81G 1VQKE 2ZJQE 3PIOE 3CCME 3CF5E 1JJ2E 1K9MG 5GAGG 1VQOE 1RL6A 3CCRE 2ZJPE 3I55E 3CCUE 1NJIG 1YIJE 5DM6E 1VQ7E 1VQPE 3OW2E 4WF9E 3CC7E 1VQ4E 1YJWE 3I56E 1QVGE 4U67E 3J7ZG 4WFAE 3CXCE 1VQME 2CQLA 3CPWE 3PIPE 5H1SI 3DLLE 3G6EE 2QEXE 2QA4E 1YITE 3CC4E 1VQ9E 1K73G 5GAHG 1VQ6E 2OTJE 1YI2E 5MLCH 5JVGE 1YJ9E 4IOCE 3CMEE 1KD1G 1VQLE 1K8AG 1KQSE 4IO9E 1YJNE 3CCSE 1Q7YG 4UY8G 1KC8G 5AN9B 3CCQE 5GADG 3G4SE 4WFNE 4WFBE 3CCJE 4IOAE 1M90G 1Q82G 1M1KG 4WCEE 1VQ5E
chains in the Genus database with same CATH superfamily
2I5VO 1P4PA 5B11O 2G8CO 2OYBO 2OL7A 3EC5A 1Q86G 5DM7E 1VQ8E 3CD6E 5HL7E 1S72E 3CC2E 1W2BE 1VQNE 2HKDA 5GAEG 1YHQE 1N8RG 2OTLE 2ZJRE 2PI3O 5B2AO 3CCVE 3CCLE 3CMAE 2OL6O 1QVFE 3CCEE 5JVHE 3G71E 1Q81G 3CKFA 1VQKE 2OY5O 2OY7A 2ZJQE 3PIOE 3CCME 3CF5E 1JJ2E 1K9MG 5GAGG 1VQOE 1RL6A 3CCRE 2ZJPE 3I55E 3CCUE 1NJIG 3AUMO 2FKJA 5B10O 1YIJE 5DM6E 1VQ7E 1VQPE 3OW2E 4WF9E 2AF5A 3CC7E 1VQ4E 1YJWE 2OY1O 3CKGA 2OY8A 3I56E 1QVGE 4U67E 3IGEA 3J7ZG 4WFAE 3CXCE 1VQME 2CQLA 2I5ZO 3CPWE 3PIPE 5H1SI 3DLLE 3G6EE 2QEXE 2QA4E 1YITE 3CC4E 1VQ9E 5B3MO 1K73G 5GAHG 1VQ6E 2OTJE 1YI2E 5MLCH 2OL8O 1OSPO 5JVGE 1YJ9E 4IOCE 3CMEE 1KD1G 1VQLE 1K8AG 1KQSE 4IO9E 1YJNE 3CCSE 1Q7YG 4UY8G 1KC8G 1RJLC 5AN9B 3CCQE 5GADG 3G4SE 4WFNE 4WFBE 3CCJE 4IOAE 1M90G 1Q82G 1FJ1E 2FKGA 1M1KG 4WCEE 1VQ5E 3IG9A
chains in the Genus database with same CATH topology
1Q86G 5DM7E 1VQ8E 3CD6E 5HL7E 1S72E 3CC2E 1W2BE 1VQNE 5GAEG 1YHQE 1N8RG 2OTLE 2ZJRE 3CCVE 3CCLE 3CMAE 1QVFE 3CCEE 5JVHE 3G71E 1Q81G 1VQKE 2ZJQE 3PIOE 3CCME 3CF5E 1JJ2E 1K9MG 5GAGG 1VQOE 1RL6A 3CCRE 2ZJPE 3I55E 3CCUE 1NJIG 1YIJE 5DM6E 1VQ7E 1VQPE 3OW2E 4WF9E 3CC7E 1VQ4E 1YJWE 3I56E 1QVGE 4U67E 3J7ZG 4WFAE 3CXCE 1VQME 2CQLA 3CPWE 3PIPE 5H1SI 3DLLE 3G6EE 2QEXE 2QA4E 1YITE 3CC4E 1VQ9E 1K73G 5GAHG 1VQ6E 2OTJE 1YI2E 5MLCH 5JVGE 1YJ9E 4IOCE 3CMEE 1KD1G 1VQLE 1K8AG 1KQSE 4IO9E 1YJNE 3CCSE 1Q7YG 4UY8G 1KC8G 5AN9B 3CCQE 5GADG 3G4SE 4WFNE 4WFBE 3CCJE 4IOAE 1M90G 1Q82G 1M1KG 4WCEE 1VQ5E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q86 G;  5DM7 E;  1VQ8 E;  3CD6 E;  5HL7 E;  1S72 E;  3CC2 E;  1W2B E;  1VQN E;  5GAE G;  1YHQ E;  1N8R G;  2OTL E;  2ZJR E;  3CCV E;  3CCL E;  3CMA E;  1QVF E;  3CCE E;  5JVH E;  3G71 E;  1Q81 G;  1VQK E;  2ZJQ E;  3PIO E;  3CCM E;  3CF5 E;  1JJ2 E;  1K9M G;  5GAG G;  1VQO E;  1RL6 A;  3CCR E;  2ZJP E;  3I55 E;  3CCU E;  1NJI G;  1YIJ E;  5DM6 E;  1VQ7 E;  1VQP E;  3OW2 E;  4WF9 E;  3CC7 E;  1VQ4 E;  1YJW E;  3I56 E;  1QVG E;  4U67 E;  3J7Z G;  4WFA E;  3CXC E;  1VQM E;  2CQL A;  3CPW E;  3PIP E;  5H1S I;  3DLL E;  3G6E E;  2QEX E;  2QA4 E;  1YIT E;  3CC4 E;  1VQ9 E;  1K73 G;  5GAH G;  1VQ6 E;  2OTJ E;  1YI2 E;  5MLC H;  5JVG E;  1YJ9 E;  4IOC E;  3CME E;  1KD1 G;  1VQL E;  1K8A G;  1KQS E;  4IO9 E;  1YJN E;  3CCS E;  1Q7Y G;  4UY8 G;  1KC8 G;  5AN9 B;  3CCQ E;  5GAD G;  3G4S E;  4WFN E;  4WFB E;  3CCJ E;  4IOA E;  1M90 G;  1Q82 G;  1M1K G;  4WCE E;  1VQ5 E; 
#chains in the Genus database with same CATH topology
 2I5V O;  1P4P A;  5B11 O;  2G8C O;  2OYB O;  2OL7 A;  3EC5 A;  1Q86 G;  5DM7 E;  1VQ8 E;  3CD6 E;  5HL7 E;  1S72 E;  3CC2 E;  1W2B E;  1VQN E;  2HKD A;  5GAE G;  1YHQ E;  1N8R G;  2OTL E;  2ZJR E;  2PI3 O;  5B2A O;  3CCV E;  3CCL E;  3CMA E;  2OL6 O;  1QVF E;  3CCE E;  5JVH E;  3G71 E;  1Q81 G;  3CKF A;  1VQK E;  2OY5 O;  2OY7 A;  2ZJQ E;  3PIO E;  3CCM E;  3CF5 E;  1JJ2 E;  1K9M G;  5GAG G;  1VQO E;  1RL6 A;  3CCR E;  2ZJP E;  3I55 E;  3CCU E;  1NJI G;  3AUM O;  2FKJ A;  5B10 O;  1YIJ E;  5DM6 E;  1VQ7 E;  1VQP E;  3OW2 E;  4WF9 E;  2AF5 A;  3CC7 E;  1VQ4 E;  1YJW E;  2OY1 O;  3CKG A;  2OY8 A;  3I56 E;  1QVG E;  4U67 E;  3IGE A;  3J7Z G;  4WFA E;  3CXC E;  1VQM E;  2CQL A;  2I5Z O;  3CPW E;  3PIP E;  5H1S I;  3DLL E;  3G6E E;  2QEX E;  2QA4 E;  1YIT E;  3CC4 E;  1VQ9 E;  5B3M O;  1K73 G;  5GAH G;  1VQ6 E;  2OTJ E;  1YI2 E;  5MLC H;  2OL8 O;  1OSP O;  5JVG E;  1YJ9 E;  4IOC E;  3CME E;  1KD1 G;  1VQL E;  1K8A G;  1KQS E;  4IO9 E;  1YJN E;  3CCS E;  1Q7Y G;  4UY8 G;  1KC8 G;  1RJL C;  5AN9 B;  3CCQ E;  5GAD G;  3G4S E;  4WFN E;  4WFB E;  3CCJ E;  4IOA E;  1M90 G;  1Q82 G;  1FJ1 E;  2FKG A;  1M1K G;  4WCE E;  1VQ5 E;  3IG9 A; 
#chains in the Genus database with same CATH homology
 1Q86 G;  5DM7 E;  1VQ8 E;  3CD6 E;  5HL7 E;  1S72 E;  3CC2 E;  1W2B E;  1VQN E;  5GAE G;  1YHQ E;  1N8R G;  2OTL E;  2ZJR E;  3CCV E;  3CCL E;  3CMA E;  1QVF E;  3CCE E;  5JVH E;  3G71 E;  1Q81 G;  1VQK E;  2ZJQ E;  3PIO E;  3CCM E;  3CF5 E;  1JJ2 E;  1K9M G;  5GAG G;  1VQO E;  1RL6 A;  3CCR E;  2ZJP E;  3I55 E;  3CCU E;  1NJI G;  1YIJ E;  5DM6 E;  1VQ7 E;  1VQP E;  3OW2 E;  4WF9 E;  3CC7 E;  1VQ4 E;  1YJW E;  3I56 E;  1QVG E;  4U67 E;  3J7Z G;  4WFA E;  3CXC E;  1VQM E;  2CQL A;  3CPW E;  3PIP E;  5H1S I;  3DLL E;  3G6E E;  2QEX E;  2QA4 E;  1YIT E;  3CC4 E;  1VQ9 E;  1K73 G;  5GAH G;  1VQ6 E;  2OTJ E;  1YI2 E;  5MLC H;  5JVG E;  1YJ9 E;  4IOC E;  3CME E;  1KD1 G;  1VQL E;  1K8A G;  1KQS E;  4IO9 E;  1YJN E;  3CCS E;  1Q7Y G;  4UY8 G;  1KC8 G;  5AN9 B;  3CCQ E;  5GAD G;  3G4S E;  4WFN E;  4WFB E;  3CCJ E;  4IOA E;  1M90 G;  1Q82 G;  1M1K G;  4WCE E;  1VQ5 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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