3CCME

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccmE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccmE01
1VQ7E 4WF9E 3I55E 1YJWE 1VQME 1Q86G 1QVFE 1VQ8E 2ZJQE 3CCSE 4WFNE 1VQPE 1VQNE 1YHQE 1YJNE 2QA4E 2OTJE 3DLLE 5GADG 3CCVE 3CCQE 1K73G 1VQ6E 3PIPE 1YITE 5HL7E 5AN9B 1YI2E 3OW2E 4IOCE 1RL6A 3CCLE 3CCJE 5GAEG 1K8AG 5GAHG 5GAGG 5H1SI 2OTLE 5JVGE 5DM7E 3CPWE 3CC4E 1Q7YG 4IO9E 1Q82G 3CMAE 5JVHE 3CCME 3CD6E 1M90G 3CCEE 5MLCH 3G6EE 2ZJPE 3CXCE 3CC7E 1M1KG 2CQLA 1YJ9E 2QEXE 3CF5E 1QVGE 1Q81G 4WFAE 3CCRE 3PIOE 1K9MG 2ZJRE 3G4SE 1VQ5E 4IOAE 5DM6E 3CC2E 4UY8G 1VQ9E 1W2BE 3G71E 3CMEE 1JJ2E 1VQ4E 1S72E 1NJIG 1KD1G 3CCUE 3I56E 1VQOE 1KC8G 1VQKE 1N8RG 3J7ZG 4WFBE 1YIJE 4U67E 4WCEE 1VQLE 1KQSE
chains in the Genus database with same CATH superfamily
1VQ7E 4WF9E 3I55E 1YJWE 1VQME 2G8CO 1Q86G 3AUMO 1QVFE 5B10O 1VQ8E 2ZJQE 3CCSE 4WFNE 1VQPE 1VQNE 1YHQE 1YJNE 3IGEA 2HKDA 1FJ1E 2QA4E 2OTJE 3DLLE 5B11O 5GADG 2OY5O 3CCVE 3CCQE 1K73G 1VQ6E 3PIPE 1YITE 5HL7E 2I5VO 5AN9B 1YI2E 3OW2E 4IOCE 1OSPO 1RL6A 3CKFA 3CCLE 3CCJE 2FKGA 1P4PA 5GAEG 1K8AG 5GAHG 5GAGG 5H1SI 2OL7A 2OYBO 2OTLE 5JVGE 3CKGA 5DM7E 3CPWE 3CC4E 3EC5A 1Q7YG 5B3MO 4IO9E 1Q82G 3CMAE 5JVHE 3CCME 3CD6E 1M90G 3CCEE 5MLCH 3G6EE 2OY8A 2ZJPE 3CXCE 3CC7E 1M1KG 5B2AO 2CQLA 1YJ9E 2I5ZO 2QEXE 3CF5E 1QVGE 1Q81G 4WFAE 3CCRE 2FKJA 2AF5A 3PIOE 1RJLC 2OY1O 1K9MG 2ZJRE 3G4SE 1VQ5E 4IOAE 5DM6E 3CC2E 4UY8G 1VQ9E 1W2BE 2OL6O 2OL8O 3G71E 3CMEE 1JJ2E 1VQ4E 1S72E 1NJIG 2OY7A 1KD1G 3CCUE 3I56E 1VQOE 1KC8G 1VQKE 1N8RG 3J7ZG 4WFBE 1YIJE 4U67E 2PI3O 3IG9A 4WCEE 1VQLE 1KQSE
chains in the Genus database with same CATH topology
1VQ7E 4WF9E 3I55E 1YJWE 1VQME 1Q86G 1QVFE 1VQ8E 2ZJQE 3CCSE 4WFNE 1VQPE 1VQNE 1YHQE 1YJNE 2QA4E 2OTJE 3DLLE 5GADG 3CCVE 3CCQE 1K73G 1VQ6E 3PIPE 1YITE 5HL7E 5AN9B 1YI2E 3OW2E 4IOCE 1RL6A 3CCLE 3CCJE 5GAEG 1K8AG 5GAHG 5GAGG 5H1SI 2OTLE 5JVGE 5DM7E 3CPWE 3CC4E 1Q7YG 4IO9E 1Q82G 3CMAE 5JVHE 3CCME 3CD6E 1M90G 3CCEE 5MLCH 3G6EE 2ZJPE 3CXCE 3CC7E 1M1KG 2CQLA 1YJ9E 2QEXE 3CF5E 1QVGE 1Q81G 4WFAE 3CCRE 3PIOE 1K9MG 2ZJRE 3G4SE 1VQ5E 4IOAE 5DM6E 3CC2E 4UY8G 1VQ9E 1W2BE 3G71E 3CMEE 1JJ2E 1VQ4E 1S72E 1NJIG 1KD1G 3CCUE 3I56E 1VQOE 1KC8G 1VQKE 1N8RG 3J7ZG 4WFBE 1YIJE 4U67E 4WCEE 1VQLE 1KQSE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ7 E;  4WF9 E;  3I55 E;  1YJW E;  1VQM E;  1Q86 G;  1QVF E;  1VQ8 E;  2ZJQ E;  3CCS E;  4WFN E;  1VQP E;  1VQN E;  1YHQ E;  1YJN E;  2QA4 E;  2OTJ E;  3DLL E;  5GAD G;  3CCV E;  3CCQ E;  1K73 G;  1VQ6 E;  3PIP E;  1YIT E;  5HL7 E;  5AN9 B;  1YI2 E;  3OW2 E;  4IOC E;  1RL6 A;  3CCL E;  3CCJ E;  5GAE G;  1K8A G;  5GAH G;  5GAG G;  5H1S I;  2OTL E;  5JVG E;  5DM7 E;  3CPW E;  3CC4 E;  1Q7Y G;  4IO9 E;  1Q82 G;  3CMA E;  5JVH E;  3CCM E;  3CD6 E;  1M90 G;  3CCE E;  5MLC H;  3G6E E;  2ZJP E;  3CXC E;  3CC7 E;  1M1K G;  2CQL A;  1YJ9 E;  2QEX E;  3CF5 E;  1QVG E;  1Q81 G;  4WFA E;  3CCR E;  3PIO E;  1K9M G;  2ZJR E;  3G4S E;  1VQ5 E;  4IOA E;  5DM6 E;  3CC2 E;  4UY8 G;  1VQ9 E;  1W2B E;  3G71 E;  3CME E;  1JJ2 E;  1VQ4 E;  1S72 E;  1NJI G;  1KD1 G;  3CCU E;  3I56 E;  1VQO E;  1KC8 G;  1VQK E;  1N8R G;  3J7Z G;  4WFB E;  1YIJ E;  4U67 E;  4WCE E;  1VQL E;  1KQS E; 
#chains in the Genus database with same CATH topology
 1VQ7 E;  4WF9 E;  3I55 E;  1YJW E;  1VQM E;  2G8C O;  1Q86 G;  3AUM O;  1QVF E;  5B10 O;  1VQ8 E;  2ZJQ E;  3CCS E;  4WFN E;  1VQP E;  1VQN E;  1YHQ E;  1YJN E;  3IGE A;  2HKD A;  1FJ1 E;  2QA4 E;  2OTJ E;  3DLL E;  5B11 O;  5GAD G;  2OY5 O;  3CCV E;  3CCQ E;  1K73 G;  1VQ6 E;  3PIP E;  1YIT E;  5HL7 E;  2I5V O;  5AN9 B;  1YI2 E;  3OW2 E;  4IOC E;  1OSP O;  1RL6 A;  3CKF A;  3CCL E;  3CCJ E;  2FKG A;  1P4P A;  5GAE G;  1K8A G;  5GAH G;  5GAG G;  5H1S I;  2OL7 A;  2OYB O;  2OTL E;  5JVG E;  3CKG A;  5DM7 E;  3CPW E;  3CC4 E;  3EC5 A;  1Q7Y G;  5B3M O;  4IO9 E;  1Q82 G;  3CMA E;  5JVH E;  3CCM E;  3CD6 E;  1M90 G;  3CCE E;  5MLC H;  3G6E E;  2OY8 A;  2ZJP E;  3CXC E;  3CC7 E;  1M1K G;  5B2A O;  2CQL A;  1YJ9 E;  2I5Z O;  2QEX E;  3CF5 E;  1QVG E;  1Q81 G;  4WFA E;  3CCR E;  2FKJ A;  2AF5 A;  3PIO E;  1RJL C;  2OY1 O;  1K9M G;  2ZJR E;  3G4S E;  1VQ5 E;  4IOA E;  5DM6 E;  3CC2 E;  4UY8 G;  1VQ9 E;  1W2B E;  2OL6 O;  2OL8 O;  3G71 E;  3CME E;  1JJ2 E;  1VQ4 E;  1S72 E;  1NJI G;  2OY7 A;  1KD1 G;  3CCU E;  3I56 E;  1VQO E;  1KC8 G;  1VQK E;  1N8R G;  3J7Z G;  4WFB E;  1YIJ E;  4U67 E;  2PI3 O;  3IG9 A;  4WCE E;  1VQL E;  1KQS E; 
#chains in the Genus database with same CATH homology
 1VQ7 E;  4WF9 E;  3I55 E;  1YJW E;  1VQM E;  1Q86 G;  1QVF E;  1VQ8 E;  2ZJQ E;  3CCS E;  4WFN E;  1VQP E;  1VQN E;  1YHQ E;  1YJN E;  2QA4 E;  2OTJ E;  3DLL E;  5GAD G;  3CCV E;  3CCQ E;  1K73 G;  1VQ6 E;  3PIP E;  1YIT E;  5HL7 E;  5AN9 B;  1YI2 E;  3OW2 E;  4IOC E;  1RL6 A;  3CCL E;  3CCJ E;  5GAE G;  1K8A G;  5GAH G;  5GAG G;  5H1S I;  2OTL E;  5JVG E;  5DM7 E;  3CPW E;  3CC4 E;  1Q7Y G;  4IO9 E;  1Q82 G;  3CMA E;  5JVH E;  3CCM E;  3CD6 E;  1M90 G;  3CCE E;  5MLC H;  3G6E E;  2ZJP E;  3CXC E;  3CC7 E;  1M1K G;  2CQL A;  1YJ9 E;  2QEX E;  3CF5 E;  1QVG E;  1Q81 G;  4WFA E;  3CCR E;  3PIO E;  1K9M G;  2ZJR E;  3G4S E;  1VQ5 E;  4IOA E;  5DM6 E;  3CC2 E;  4UY8 G;  1VQ9 E;  1W2B E;  3G71 E;  3CME E;  1JJ2 E;  1VQ4 E;  1S72 E;  1NJI G;  1KD1 G;  3CCU E;  3I56 E;  1VQO E;  1KC8 G;  1VQK E;  1N8R G;  3J7Z G;  4WFB E;  1YIJ E;  4U67 E;  4WCE E;  1VQL E;  1KQS E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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