3CCQE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccqE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccqE01
1JJ2E 1Q82G 1KD1G 1VQ7E 4WF9E 3CCME 3CF5E 1M1KG 3G4SE 4WCEE 1N8RG 5HL7E 1QVGE 4WFNE 4IO9E 1S72E 2QEXE 5AN9B 5GADG 1VQOE 3CMAE 5GAHG 3CXCE 1YITE 3CC4E 3I55E 3G71E 2ZJQE 2ZJPE 4WFAE 1VQ8E 3CPWE 1VQLE 1VQ4E 1VQ5E 4WFBE 5JVHE 1K73G 1Q81G 2OTJE 3CCEE 3OW2E 1W2BE 4UY8G 1YIJE 3CD6E 1M90G 1KQSE 3CCUE 5H1SI 1Q7YG 5DM7E 3CCLE 5DM6E 1YHQE 4U67E 3PIPE 2OTLE 4IOCE 1VQ6E 3CCSE 3CCQE 1Q86G 2ZJRE 3PIOE 1K8AG 5JVGE 1YJWE 3CMEE 1VQPE 3CCVE 2QA4E 3DLLE 4IOAE 1NJIG 1VQNE 3I56E 1QVFE 3CC7E 1KC8G 3CCRE 3CCJE 1VQME 1YJ9E 2CQLA 5MLCH 3J7ZG 1YI2E 1VQKE 5GAEG 5GAGG 3CC2E 1VQ9E 1YJNE 1RL6A 1K9MG 3G6EE
chains in the Genus database with same CATH superfamily
1JJ2E 1Q82G 1KD1G 1VQ7E 4WF9E 3CCME 3CF5E 1M1KG 2OL6O 3G4SE 4WCEE 1N8RG 5HL7E 1QVGE 3IG9A 3CKFA 4WFNE 4IO9E 1S72E 2QEXE 2OL7A 5AN9B 5GADG 1VQOE 3CMAE 5GAHG 3CXCE 1YITE 3CC4E 3I55E 3G71E 2FKGA 2ZJQE 3AUMO 2ZJPE 4WFAE 2OY1O 2FKJA 1VQ8E 3CPWE 1VQLE 1VQ4E 1VQ5E 4WFBE 3CKGA 5JVHE 1K73G 5B2AO 2OY8A 1Q81G 2OY5O 2OTJE 3CCEE 3OW2E 2AF5A 1W2BE 4UY8G 1YIJE 5B3MO 3CD6E 1M90G 1KQSE 1RJLC 3CCUE 5H1SI 1P4PA 1Q7YG 5DM7E 3CCLE 5DM6E 1YHQE 4U67E 3PIPE 2OTLE 2I5ZO 4IOCE 1VQ6E 3CCSE 3CCQE 1Q86G 2ZJRE 3PIOE 1K8AG 5JVGE 1OSPO 2OYBO 2I5VO 1YJWE 3CMEE 1VQPE 3CCVE 2QA4E 3DLLE 4IOAE 1NJIG 1VQNE 3I56E 1QVFE 2HKDA 3CC7E 3CCRE 3CCJE 1VQME 1YJ9E 1KC8G 2CQLA 3EC5A 5MLCH 2OL8O 2PI3O 3J7ZG 1YI2E 1VQKE 1FJ1E 5GAEG 5B10O 5GAGG 3CC2E 1VQ9E 5B11O 1YJNE 3IGEA 1RL6A 2G8CO 1K9MG 2OY7A 3G6EE
chains in the Genus database with same CATH topology
1JJ2E 1Q82G 1KD1G 1VQ7E 4WF9E 3CCME 3CF5E 1M1KG 3G4SE 4WCEE 1N8RG 5HL7E 1QVGE 4WFNE 4IO9E 1S72E 2QEXE 5AN9B 5GADG 1VQOE 3CMAE 5GAHG 3CXCE 1YITE 3CC4E 3I55E 3G71E 2ZJQE 2ZJPE 4WFAE 1VQ8E 3CPWE 1VQLE 1VQ4E 1VQ5E 4WFBE 5JVHE 1K73G 1Q81G 2OTJE 3CCEE 3OW2E 1W2BE 4UY8G 1YIJE 3CD6E 1M90G 1KQSE 3CCUE 5H1SI 1Q7YG 5DM7E 3CCLE 5DM6E 1YHQE 4U67E 3PIPE 2OTLE 4IOCE 1VQ6E 3CCSE 3CCQE 1Q86G 2ZJRE 3PIOE 1K8AG 5JVGE 1YJWE 3CMEE 1VQPE 3CCVE 2QA4E 3DLLE 4IOAE 1NJIG 1VQNE 3I56E 1QVFE 3CC7E 1KC8G 3CCRE 3CCJE 1VQME 1YJ9E 2CQLA 5MLCH 3J7ZG 1YI2E 1VQKE 5GAEG 5GAGG 3CC2E 1VQ9E 1YJNE 1RL6A 1K9MG 3G6EE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JJ2 E;  1Q82 G;  1KD1 G;  1VQ7 E;  4WF9 E;  3CCM E;  3CF5 E;  1M1K G;  3G4S E;  4WCE E;  1N8R G;  5HL7 E;  1QVG E;  4WFN E;  4IO9 E;  1S72 E;  2QEX E;  5AN9 B;  5GAD G;  1VQO E;  3CMA E;  5GAH G;  3CXC E;  1YIT E;  3CC4 E;  3I55 E;  3G71 E;  2ZJQ E;  2ZJP E;  4WFA E;  1VQ8 E;  3CPW E;  1VQL E;  1VQ4 E;  1VQ5 E;  4WFB E;  5JVH E;  1K73 G;  1Q81 G;  2OTJ E;  3CCE E;  3OW2 E;  1W2B E;  4UY8 G;  1YIJ E;  3CD6 E;  1M90 G;  1KQS E;  3CCU E;  5H1S I;  1Q7Y G;  5DM7 E;  3CCL E;  5DM6 E;  1YHQ E;  4U67 E;  3PIP E;  2OTL E;  4IOC E;  1VQ6 E;  3CCS E;  3CCQ E;  1Q86 G;  2ZJR E;  3PIO E;  1K8A G;  5JVG E;  1YJW E;  3CME E;  1VQP E;  3CCV E;  2QA4 E;  3DLL E;  4IOA E;  1NJI G;  1VQN E;  3I56 E;  1QVF E;  3CC7 E;  1KC8 G;  3CCR E;  3CCJ E;  1VQM E;  1YJ9 E;  2CQL A;  5MLC H;  3J7Z G;  1YI2 E;  1VQK E;  5GAE G;  5GAG G;  3CC2 E;  1VQ9 E;  1YJN E;  1RL6 A;  1K9M G;  3G6E E; 
#chains in the Genus database with same CATH topology
 1JJ2 E;  1Q82 G;  1KD1 G;  1VQ7 E;  4WF9 E;  3CCM E;  3CF5 E;  1M1K G;  2OL6 O;  3G4S E;  4WCE E;  1N8R G;  5HL7 E;  1QVG E;  3IG9 A;  3CKF A;  4WFN E;  4IO9 E;  1S72 E;  2QEX E;  2OL7 A;  5AN9 B;  5GAD G;  1VQO E;  3CMA E;  5GAH G;  3CXC E;  1YIT E;  3CC4 E;  3I55 E;  3G71 E;  2FKG A;  2ZJQ E;  3AUM O;  2ZJP E;  4WFA E;  2OY1 O;  2FKJ A;  1VQ8 E;  3CPW E;  1VQL E;  1VQ4 E;  1VQ5 E;  4WFB E;  3CKG A;  5JVH E;  1K73 G;  5B2A O;  2OY8 A;  1Q81 G;  2OY5 O;  2OTJ E;  3CCE E;  3OW2 E;  2AF5 A;  1W2B E;  4UY8 G;  1YIJ E;  5B3M O;  3CD6 E;  1M90 G;  1KQS E;  1RJL C;  3CCU E;  5H1S I;  1P4P A;  1Q7Y G;  5DM7 E;  3CCL E;  5DM6 E;  1YHQ E;  4U67 E;  3PIP E;  2OTL E;  2I5Z O;  4IOC E;  1VQ6 E;  3CCS E;  3CCQ E;  1Q86 G;  2ZJR E;  3PIO E;  1K8A G;  5JVG E;  1OSP O;  2OYB O;  2I5V O;  1YJW E;  3CME E;  1VQP E;  3CCV E;  2QA4 E;  3DLL E;  4IOA E;  1NJI G;  1VQN E;  3I56 E;  1QVF E;  2HKD A;  3CC7 E;  3CCR E;  3CCJ E;  1VQM E;  1YJ9 E;  1KC8 G;  2CQL A;  3EC5 A;  5MLC H;  2OL8 O;  2PI3 O;  3J7Z G;  1YI2 E;  1VQK E;  1FJ1 E;  5GAE G;  5B10 O;  5GAG G;  3CC2 E;  1VQ9 E;  5B11 O;  1YJN E;  3IGE A;  1RL6 A;  2G8C O;  1K9M G;  2OY7 A;  3G6E E; 
#chains in the Genus database with same CATH homology
 1JJ2 E;  1Q82 G;  1KD1 G;  1VQ7 E;  4WF9 E;  3CCM E;  3CF5 E;  1M1K G;  3G4S E;  4WCE E;  1N8R G;  5HL7 E;  1QVG E;  4WFN E;  4IO9 E;  1S72 E;  2QEX E;  5AN9 B;  5GAD G;  1VQO E;  3CMA E;  5GAH G;  3CXC E;  1YIT E;  3CC4 E;  3I55 E;  3G71 E;  2ZJQ E;  2ZJP E;  4WFA E;  1VQ8 E;  3CPW E;  1VQL E;  1VQ4 E;  1VQ5 E;  4WFB E;  5JVH E;  1K73 G;  1Q81 G;  2OTJ E;  3CCE E;  3OW2 E;  1W2B E;  4UY8 G;  1YIJ E;  3CD6 E;  1M90 G;  1KQS E;  3CCU E;  5H1S I;  1Q7Y G;  5DM7 E;  3CCL E;  5DM6 E;  1YHQ E;  4U67 E;  3PIP E;  2OTL E;  4IOC E;  1VQ6 E;  3CCS E;  3CCQ E;  1Q86 G;  2ZJR E;  3PIO E;  1K8A G;  5JVG E;  1YJW E;  3CME E;  1VQP E;  3CCV E;  2QA4 E;  3DLL E;  4IOA E;  1NJI G;  1VQN E;  3I56 E;  1QVF E;  3CC7 E;  1KC8 G;  3CCR E;  3CCJ E;  1VQM E;  1YJ9 E;  2CQL A;  5MLC H;  3J7Z G;  1YI2 E;  1VQK E;  5GAE G;  5GAG G;  3CC2 E;  1VQ9 E;  1YJN E;  1RL6 A;  1K9M G;  3G6E E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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