3CD6E

Co-cystal of large ribosomal subunit mutant g2616a with cc-puromycin
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 39
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cd6E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cd6E01
3CCME 5HL7E 1YJWE 2ZJPE 4WFNE 3CMEE 1K9MG 3J7ZG 1Q82G 5GAGG 1VQLE 1VQOE 2QEXE 3CCSE 2OTLE 5GADG 3G4SE 3CCEE 1KD1G 5H1SI 3PIPE 1M1KG 2ZJRE 1VQPE 1VQ9E 1YITE 3OW2E 1NJIG 1VQ4E 3CCJE 4IOCE 3CCRE 1YJNE 4IOAE 3G71E 1S72E 5GAEG 3CCQE 1VQ6E 2OTJE 1K73G 3DLLE 3CCVE 3CD6E 3I55E 3CXCE 1YHQE 3PIOE 4UY8G 1QVGE 1RL6A 1N8RG 4WF9E 2QA4E 3I56E 3CPWE 4IO9E 3CCLE 1VQ7E 3CC4E 5JVGE 5DM7E 5GAHG 4U67E 1Q81G 2ZJQE 4WCEE 2CQLA 1QVFE 3CCUE 5AN9B 3CC2E 1JJ2E 1VQKE 1YJ9E 1M90G 4WFBE 1KQSE 1VQNE 1VQME 4WFAE 1VQ5E 5DM6E 5JVHE 1W2BE 1Q7YG 3CC7E 1KC8G 3CMAE 5MLCH 1VQ8E 3G6EE 1YI2E 3CF5E 1YIJE 1Q86G 1K8AG
chains in the Genus database with same CATH superfamily
3CCME 2OY5O 5HL7E 1YJWE 2ZJPE 4WFNE 2OL7A 3IGEA 3CMEE 1K9MG 3J7ZG 5B11O 1Q82G 1FJ1E 5GAGG 2G8CO 5B2AO 2OL8O 1VQLE 1VQOE 2QEXE 2OY7A 2OL6O 3CCSE 2OTLE 2OY1O 5GADG 3G4SE 3CCEE 2I5VO 2OYBO 1KD1G 5H1SI 3PIPE 1M1KG 2ZJRE 1VQPE 2HKDA 1P4PA 2FKJA 1OSPO 1VQ9E 1YITE 3OW2E 1NJIG 1VQ4E 3CCJE 4IOCE 3CCRE 1YJNE 4IOAE 3G71E 1S72E 5GAEG 3CCQE 1VQ6E 2OTJE 1K73G 3CKGA 3DLLE 3EC5A 3CCVE 3CD6E 2OY8A 3AUMO 3I55E 3CXCE 1YHQE 3PIOE 4UY8G 1QVGE 1RL6A 1N8RG 4WF9E 1RJLC 3CKFA 3I56E 2QA4E 3CPWE 4IO9E 3CCLE 1VQ7E 2I5ZO 3CC4E 5JVGE 3IG9A 5DM7E 5GAHG 5B3MO 4U67E 1Q81G 2ZJQE 2CQLA 4WCEE 1QVFE 3CCUE 5AN9B 3CC2E 2PI3O 1JJ2E 1VQKE 1YJ9E 2AF5A 1M90G 4WFBE 1KQSE 1VQNE 1VQME 4WFAE 1VQ5E 5DM6E 5JVHE 1W2BE 1Q7YG 3CC7E 1KC8G 2FKGA 3CMAE 5B10O 5MLCH 1VQ8E 3G6EE 1YI2E 3CF5E 1YIJE 1Q86G 1K8AG
chains in the Genus database with same CATH topology
3CCME 5HL7E 1YJWE 2ZJPE 4WFNE 3CMEE 1K9MG 3J7ZG 1Q82G 5GAGG 1VQLE 1VQOE 2QEXE 3CCSE 2OTLE 5GADG 3G4SE 3CCEE 1KD1G 5H1SI 3PIPE 1M1KG 2ZJRE 1VQPE 1VQ9E 1YITE 3OW2E 1NJIG 1VQ4E 3CCJE 4IOCE 3CCRE 1YJNE 4IOAE 3G71E 1S72E 5GAEG 3CCQE 1VQ6E 2OTJE 1K73G 3DLLE 3CCVE 3CD6E 3I55E 3CXCE 1YHQE 3PIOE 4UY8G 1QVGE 1RL6A 1N8RG 4WF9E 2QA4E 3I56E 3CPWE 4IO9E 3CCLE 1VQ7E 3CC4E 5JVGE 5DM7E 5GAHG 4U67E 1Q81G 2ZJQE 4WCEE 2CQLA 1QVFE 3CCUE 5AN9B 3CC2E 1JJ2E 1VQKE 1YJ9E 1M90G 4WFBE 1KQSE 1VQNE 1VQME 4WFAE 1VQ5E 5DM6E 5JVHE 1W2BE 1Q7YG 3CC7E 1KC8G 3CMAE 5MLCH 1VQ8E 3G6EE 1YI2E 3CF5E 1YIJE 1Q86G 1K8AG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCM E;  5HL7 E;  1YJW E;  2ZJP E;  4WFN E;  3CME E;  1K9M G;  3J7Z G;  1Q82 G;  5GAG G;  1VQL E;  1VQO E;  2QEX E;  3CCS E;  2OTL E;  5GAD G;  3G4S E;  3CCE E;  1KD1 G;  5H1S I;  3PIP E;  1M1K G;  2ZJR E;  1VQP E;  1VQ9 E;  1YIT E;  3OW2 E;  1NJI G;  1VQ4 E;  3CCJ E;  4IOC E;  3CCR E;  1YJN E;  4IOA E;  3G71 E;  1S72 E;  5GAE G;  3CCQ E;  1VQ6 E;  2OTJ E;  1K73 G;  3DLL E;  3CCV E;  3CD6 E;  3I55 E;  3CXC E;  1YHQ E;  3PIO E;  4UY8 G;  1QVG E;  1RL6 A;  1N8R G;  4WF9 E;  2QA4 E;  3I56 E;  3CPW E;  4IO9 E;  3CCL E;  1VQ7 E;  3CC4 E;  5JVG E;  5DM7 E;  5GAH G;  4U67 E;  1Q81 G;  2ZJQ E;  4WCE E;  2CQL A;  1QVF E;  3CCU E;  5AN9 B;  3CC2 E;  1JJ2 E;  1VQK E;  1YJ9 E;  1M90 G;  4WFB E;  1KQS E;  1VQN E;  1VQM E;  4WFA E;  1VQ5 E;  5DM6 E;  5JVH E;  1W2B E;  1Q7Y G;  3CC7 E;  1KC8 G;  3CMA E;  5MLC H;  1VQ8 E;  3G6E E;  1YI2 E;  3CF5 E;  1YIJ E;  1Q86 G;  1K8A G; 
#chains in the Genus database with same CATH topology
 3CCM E;  2OY5 O;  5HL7 E;  1YJW E;  2ZJP E;  4WFN E;  2OL7 A;  3IGE A;  3CME E;  1K9M G;  3J7Z G;  5B11 O;  1Q82 G;  1FJ1 E;  5GAG G;  2G8C O;  5B2A O;  2OL8 O;  1VQL E;  1VQO E;  2QEX E;  2OY7 A;  2OL6 O;  3CCS E;  2OTL E;  2OY1 O;  5GAD G;  3G4S E;  3CCE E;  2I5V O;  2OYB O;  1KD1 G;  5H1S I;  3PIP E;  1M1K G;  2ZJR E;  1VQP E;  2HKD A;  1P4P A;  2FKJ A;  1OSP O;  1VQ9 E;  1YIT E;  3OW2 E;  1NJI G;  1VQ4 E;  3CCJ E;  4IOC E;  3CCR E;  1YJN E;  4IOA E;  3G71 E;  1S72 E;  5GAE G;  3CCQ E;  1VQ6 E;  2OTJ E;  1K73 G;  3CKG A;  3DLL E;  3EC5 A;  3CCV E;  3CD6 E;  2OY8 A;  3AUM O;  3I55 E;  3CXC E;  1YHQ E;  3PIO E;  4UY8 G;  1QVG E;  1RL6 A;  1N8R G;  4WF9 E;  1RJL C;  3CKF A;  3I56 E;  2QA4 E;  3CPW E;  4IO9 E;  3CCL E;  1VQ7 E;  2I5Z O;  3CC4 E;  5JVG E;  3IG9 A;  5DM7 E;  5GAH G;  5B3M O;  4U67 E;  1Q81 G;  2ZJQ E;  2CQL A;  4WCE E;  1QVF E;  3CCU E;  5AN9 B;  3CC2 E;  2PI3 O;  1JJ2 E;  1VQK E;  1YJ9 E;  2AF5 A;  1M90 G;  4WFB E;  1KQS E;  1VQN E;  1VQM E;  4WFA E;  1VQ5 E;  5DM6 E;  5JVH E;  1W2B E;  1Q7Y G;  3CC7 E;  1KC8 G;  2FKG A;  3CMA E;  5B10 O;  5MLC H;  1VQ8 E;  3G6E E;  1YI2 E;  3CF5 E;  1YIJ E;  1Q86 G;  1K8A G; 
#chains in the Genus database with same CATH homology
 3CCM E;  5HL7 E;  1YJW E;  2ZJP E;  4WFN E;  3CME E;  1K9M G;  3J7Z G;  1Q82 G;  5GAG G;  1VQL E;  1VQO E;  2QEX E;  3CCS E;  2OTL E;  5GAD G;  3G4S E;  3CCE E;  1KD1 G;  5H1S I;  3PIP E;  1M1K G;  2ZJR E;  1VQP E;  1VQ9 E;  1YIT E;  3OW2 E;  1NJI G;  1VQ4 E;  3CCJ E;  4IOC E;  3CCR E;  1YJN E;  4IOA E;  3G71 E;  1S72 E;  5GAE G;  3CCQ E;  1VQ6 E;  2OTJ E;  1K73 G;  3DLL E;  3CCV E;  3CD6 E;  3I55 E;  3CXC E;  1YHQ E;  3PIO E;  4UY8 G;  1QVG E;  1RL6 A;  1N8R G;  4WF9 E;  2QA4 E;  3I56 E;  3CPW E;  4IO9 E;  3CCL E;  1VQ7 E;  3CC4 E;  5JVG E;  5DM7 E;  5GAH G;  4U67 E;  1Q81 G;  2ZJQ E;  4WCE E;  2CQL A;  1QVF E;  3CCU E;  5AN9 B;  3CC2 E;  1JJ2 E;  1VQK E;  1YJ9 E;  1M90 G;  4WFB E;  1KQS E;  1VQN E;  1VQM E;  4WFA E;  1VQ5 E;  5DM6 E;  5JVH E;  1W2B E;  1Q7Y G;  3CC7 E;  1KC8 G;  3CMA E;  5MLC H;  1VQ8 E;  3G6E E;  1YI2 E;  3CF5 E;  1YIJ E;  1Q86 G;  1K8A G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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