3CXCE

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE01
4IOAE 4WFBE 1M90G 5MLCH 1S72E 5HL7E 1VQ9E 1YHQE 5GAHG 5H1SI 1VQ4E 2OTJE 1N8RG 1QVGE 1KQSE 1RL6A 1YJ9E 1K73G 1YJWE 3CCUE 2QEXE 1Q7YG 4WF9E 2CQLA 1JJ2E 5AN9B 3PIPE 3CCLE 5GADG 2OTLE 3I56E 3PIOE 1W2BE 3CCME 1VQ6E 1VQNE 4IOCE 1VQOE 4UY8G 4WFNE 2ZJRE 1VQPE 5JVHE 4WCEE 3CCSE 3CCQE 1QVFE 5DM7E 1NJIG 1K9MG 3CMAE 3CCJE 3CMEE 3CCEE 3J7ZG 2QA4E 2ZJQE 2ZJPE 3G6EE 3CC4E 3CC2E 3CD6E 3G4SE 1YJNE 5GAGG 1YI2E 1Q82G 1VQLE 4U67E 1M1KG 3CPWE 5DM6E 1VQME 1KD1G 3G71E 4IO9E 3CCVE 5JVGE 1K8AG 1Q86G 3DLLE 3OW2E 3I55E 3CXCE 5GAEG 4WFAE 3CF5E 1Q81G 1VQ5E 1KC8G 1VQKE 3CC7E 3CCRE 1VQ8E 1YIJE 1YITE 1VQ7E
chains in the Genus database with same CATH superfamily
4IOAE 4WFBE 1M90G 5MLCH 1S72E 5HL7E 1VQ9E 2FKGA 2PI3O 1YHQE 5GAHG 5H1SI 1VQ4E 2OTJE 1N8RG 1QVGE 1KQSE 3AUMO 2G8CO 1RL6A 1YJ9E 1K73G 1YJWE 3CCUE 2QEXE 1Q7YG 3CKGA 4WF9E 2CQLA 1JJ2E 5AN9B 3PIPE 3CCLE 5GADG 2OY7A 2OTLE 3IG9A 3I56E 3PIOE 1W2BE 3CCME 1VQ6E 1VQNE 4IOCE 1VQOE 1YIJE 4UY8G 4WFNE 2ZJRE 1VQPE 5JVHE 4WCEE 5B2AO 3CCSE 3CCQE 1P4PA 3EC5A 1QVFE 5DM7E 1NJIG 3IGEA 1K9MG 3CMAE 3CCJE 3CMEE 2OYBO 2OY1O 2AF5A 3CCEE 3J7ZG 2QA4E 2ZJQE 2ZJPE 3G6EE 3CC4E 2I5VO 3CC2E 2OL6O 3CD6E 3G4SE 1YJNE 2FKJA 5GAGG 1YI2E 1OSPO 1Q82G 1FJ1E 1VQLE 4U67E 1M1KG 3CPWE 5DM6E 1VQME 1KD1G 1RJLC 3G71E 3CCVE 4IO9E 5JVGE 2OY5O 2I5ZO 1K8AG 1Q86G 3DLLE 3OW2E 3I55E 3CXCE 2OY8A 5GAEG 4WFAE 2OL8O 5B3MO 3CF5E 1Q81G 1VQ5E 2HKDA 2OL7A 1KC8G 5B10O 1VQKE 3CKFA 3CC7E 3CCRE 1VQ8E 5B11O 1YITE 1VQ7E
chains in the Genus database with same CATH topology
4IOAE 4WFBE 1M90G 5MLCH 1S72E 5HL7E 1VQ9E 1YHQE 5GAHG 5H1SI 1VQ4E 2OTJE 1N8RG 1QVGE 1KQSE 1RL6A 1YJ9E 1K73G 1YJWE 3CCUE 2QEXE 1Q7YG 4WF9E 2CQLA 1JJ2E 5AN9B 3PIPE 3CCLE 5GADG 2OTLE 3I56E 3PIOE 1W2BE 3CCME 1VQ6E 1VQNE 4IOCE 1VQOE 4UY8G 4WFNE 2ZJRE 1VQPE 5JVHE 4WCEE 3CCSE 3CCQE 1QVFE 5DM7E 1NJIG 1K9MG 3CMAE 3CCJE 3CMEE 3CCEE 3J7ZG 2QA4E 2ZJQE 2ZJPE 3G6EE 3CC4E 3CC2E 3CD6E 3G4SE 1YJNE 5GAGG 1YI2E 1Q82G 1VQLE 4U67E 1M1KG 3CPWE 5DM6E 1VQME 1KD1G 3G71E 4IO9E 3CCVE 5JVGE 1K8AG 1Q86G 3DLLE 3OW2E 3I55E 3CXCE 5GAEG 4WFAE 3CF5E 1Q81G 1VQ5E 1KC8G 1VQKE 3CC7E 3CCRE 1VQ8E 1YIJE 1YITE 1VQ7E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IOA E;  4WFB E;  1M90 G;  5MLC H;  1S72 E;  5HL7 E;  1VQ9 E;  1YHQ E;  5GAH G;  5H1S I;  1VQ4 E;  2OTJ E;  1N8R G;  1QVG E;  1KQS E;  1RL6 A;  1YJ9 E;  1K73 G;  1YJW E;  3CCU E;  2QEX E;  1Q7Y G;  4WF9 E;  2CQL A;  1JJ2 E;  5AN9 B;  3PIP E;  3CCL E;  5GAD G;  2OTL E;  3I56 E;  3PIO E;  1W2B E;  3CCM E;  1VQ6 E;  1VQN E;  4IOC E;  1VQO E;  4UY8 G;  4WFN E;  2ZJR E;  1VQP E;  5JVH E;  4WCE E;  3CCS E;  3CCQ E;  1QVF E;  5DM7 E;  1NJI G;  1K9M G;  3CMA E;  3CCJ E;  3CME E;  3CCE E;  3J7Z G;  2QA4 E;  2ZJQ E;  2ZJP E;  3G6E E;  3CC4 E;  3CC2 E;  3CD6 E;  3G4S E;  1YJN E;  5GAG G;  1YI2 E;  1Q82 G;  1VQL E;  4U67 E;  1M1K G;  3CPW E;  5DM6 E;  1VQM E;  1KD1 G;  3G71 E;  4IO9 E;  3CCV E;  5JVG E;  1K8A G;  1Q86 G;  3DLL E;  3OW2 E;  3I55 E;  3CXC E;  5GAE G;  4WFA E;  3CF5 E;  1Q81 G;  1VQ5 E;  1KC8 G;  1VQK E;  3CC7 E;  3CCR E;  1VQ8 E;  1YIJ E;  1YIT E;  1VQ7 E; 
#chains in the Genus database with same CATH topology
 4IOA E;  4WFB E;  1M90 G;  5MLC H;  1S72 E;  5HL7 E;  1VQ9 E;  2FKG A;  2PI3 O;  1YHQ E;  5GAH G;  5H1S I;  1VQ4 E;  2OTJ E;  1N8R G;  1QVG E;  1KQS E;  3AUM O;  2G8C O;  1RL6 A;  1YJ9 E;  1K73 G;  1YJW E;  3CCU E;  2QEX E;  1Q7Y G;  3CKG A;  4WF9 E;  2CQL A;  1JJ2 E;  5AN9 B;  3PIP E;  3CCL E;  5GAD G;  2OY7 A;  2OTL E;  3IG9 A;  3I56 E;  3PIO E;  1W2B E;  3CCM E;  1VQ6 E;  1VQN E;  4IOC E;  1VQO E;  1YIJ E;  4UY8 G;  4WFN E;  2ZJR E;  1VQP E;  5JVH E;  4WCE E;  5B2A O;  3CCS E;  3CCQ E;  1P4P A;  3EC5 A;  1QVF E;  5DM7 E;  1NJI G;  3IGE A;  1K9M G;  3CMA E;  3CCJ E;  3CME E;  2OYB O;  2OY1 O;  2AF5 A;  3CCE E;  3J7Z G;  2QA4 E;  2ZJQ E;  2ZJP E;  3G6E E;  3CC4 E;  2I5V O;  3CC2 E;  2OL6 O;  3CD6 E;  3G4S E;  1YJN E;  2FKJ A;  5GAG G;  1YI2 E;  1OSP O;  1Q82 G;  1FJ1 E;  1VQL E;  4U67 E;  1M1K G;  3CPW E;  5DM6 E;  1VQM E;  1KD1 G;  1RJL C;  3G71 E;  3CCV E;  4IO9 E;  5JVG E;  2OY5 O;  2I5Z O;  1K8A G;  1Q86 G;  3DLL E;  3OW2 E;  3I55 E;  3CXC E;  2OY8 A;  5GAE G;  4WFA E;  2OL8 O;  5B3M O;  3CF5 E;  1Q81 G;  1VQ5 E;  2HKD A;  2OL7 A;  1KC8 G;  5B10 O;  1VQK E;  3CKF A;  3CC7 E;  3CCR E;  1VQ8 E;  5B11 O;  1YIT E;  1VQ7 E; 
#chains in the Genus database with same CATH homology
 4IOA E;  4WFB E;  1M90 G;  5MLC H;  1S72 E;  5HL7 E;  1VQ9 E;  1YHQ E;  5GAH G;  5H1S I;  1VQ4 E;  2OTJ E;  1N8R G;  1QVG E;  1KQS E;  1RL6 A;  1YJ9 E;  1K73 G;  1YJW E;  3CCU E;  2QEX E;  1Q7Y G;  4WF9 E;  2CQL A;  1JJ2 E;  5AN9 B;  3PIP E;  3CCL E;  5GAD G;  2OTL E;  3I56 E;  3PIO E;  1W2B E;  3CCM E;  1VQ6 E;  1VQN E;  4IOC E;  1VQO E;  4UY8 G;  4WFN E;  2ZJR E;  1VQP E;  5JVH E;  4WCE E;  3CCS E;  3CCQ E;  1QVF E;  5DM7 E;  1NJI G;  1K9M G;  3CMA E;  3CCJ E;  3CME E;  3CCE E;  3J7Z G;  2QA4 E;  2ZJQ E;  2ZJP E;  3G6E E;  3CC4 E;  3CC2 E;  3CD6 E;  3G4S E;  1YJN E;  5GAG G;  1YI2 E;  1Q82 G;  1VQL E;  4U67 E;  1M1K G;  3CPW E;  5DM6 E;  1VQM E;  1KD1 G;  3G71 E;  4IO9 E;  3CCV E;  5JVG E;  1K8A G;  1Q86 G;  3DLL E;  3OW2 E;  3I55 E;  3CXC E;  5GAE G;  4WFA E;  3CF5 E;  1Q81 G;  1VQ5 E;  1KC8 G;  1VQK E;  3CC7 E;  3CCR E;  1VQ8 E;  1YIJ E;  1YIT E;  1VQ7 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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