3CXCE

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 37
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE01
1VQKE 3CF5E 1YI2E 4WFNE 1Q86G 5DM7E 1YITE 1YIJE 4IOAE 4WFBE 2CQLA 3J7ZG 1VQOE 5HL7E 3G71E 3CCRE 4WCEE 3I55E 1Q7YG 3CD6E 1YJNE 5GAGG 4IOCE 1YJ9E 2QA4E 1W2BE 1VQME 1VQ8E 4UY8G 2QEXE 5DM6E 1M1KG 3CCME 1JJ2E 4WF9E 3PIPE 1S72E 1K73G 1KC8G 2OTLE 3CCEE 3CPWE 3DLLE 5JVHE 2ZJRE 1VQNE 3CXCE 1N8RG 3G4SE 3CC7E 1VQ7E 1K9MG 1VQ4E 5GAEG 1Q81G 1VQ9E 1VQ6E 5GADG 3CC2E 1NJIG 1YHQE 1KQSE 3CMEE 3CCJE 1KD1G 3CC4E 4U67E 3G6EE 1Q82G 3CCQE 2OTJE 5MLCH 3CCSE 1RL6A 3CCUE 1QVGE 3CCLE 1QVFE 4WFAE 5AN9B 3I56E 2ZJQE 2ZJPE 1YJWE 5H1SI 5GAHG 1VQ5E 1K8AG 4IO9E 1VQPE 1VQLE 3PIOE 3CMAE 3OW2E 3CCVE 5JVGE 1M90G
chains in the Genus database with same CATH superfamily
1VQKE 3CF5E 1YI2E 4WFNE 1Q86G 5DM7E 1YITE 1YIJE 4IOAE 4WFBE 2CQLA 3J7ZG 1VQOE 2OY8A 5HL7E 3G71E 3CCRE 4WCEE 3I55E 1Q7YG 3CD6E 5GAGG 1YJNE 4IOCE 1YJ9E 2QA4E 1W2BE 3IGEA 1VQME 1VQ8E 4UY8G 2QEXE 1OSPO 5DM6E 1P4PA 3AUMO 1M1KG 2PI3O 3CCME 1JJ2E 2AF5A 4WF9E 5B10O 3PIPE 1S72E 1K73G 1KC8G 2OTLE 3CCEE 3CPWE 2I5ZO 3DLLE 5JVHE 2ZJRE 1VQNE 2FKGA 3CXCE 3G4SE 1N8RG 3CC7E 1VQ7E 1K9MG 1VQ4E 5GAEG 5B3MO 1Q81G 1VQ9E 1VQ6E 2FKJA 5GADG 3IG9A 3CC2E 1NJIG 1YHQE 1KQSE 3CMEE 3CCJE 1KD1G 3CC4E 2OL7A 2G8CO 2I5VO 1FJ1E 4U67E 3G6EE 1Q82G 3CCQE 2OTJE 5MLCH 3CCSE 1RL6A 3CCUE 3CKGA 1QVGE 3CCLE 3CKFA 1QVFE 2OY7A 2OYBO 4WFAE 5AN9B 2OY1O 2OY5O 2OL8O 3I56E 2ZJQE 2ZJPE 1YJWE 3EC5A 5H1SI 5GAHG 1VQ5E 1RJLC 1K8AG 5B2AO 5B11O 4IO9E 1VQPE 1VQLE 3PIOE 3CMAE 3OW2E 3CCVE 5JVGE 1M90G 2OL6O 2HKDA
chains in the Genus database with same CATH topology
1VQKE 3CF5E 1YI2E 4WFNE 1Q86G 5DM7E 1YITE 1YIJE 4IOAE 4WFBE 2CQLA 3J7ZG 1VQOE 5HL7E 3G71E 3CCRE 4WCEE 3I55E 1Q7YG 3CD6E 1YJNE 5GAGG 4IOCE 1YJ9E 2QA4E 1W2BE 1VQME 1VQ8E 4UY8G 2QEXE 5DM6E 1M1KG 3CCME 1JJ2E 4WF9E 3PIPE 1S72E 1K73G 1KC8G 2OTLE 3CCEE 3CPWE 3DLLE 5JVHE 2ZJRE 1VQNE 3CXCE 1N8RG 3G4SE 3CC7E 1VQ7E 1K9MG 1VQ4E 5GAEG 1Q81G 1VQ9E 1VQ6E 5GADG 3CC2E 1NJIG 1YHQE 1KQSE 3CMEE 3CCJE 1KD1G 3CC4E 4U67E 3G6EE 1Q82G 3CCQE 2OTJE 5MLCH 3CCSE 1RL6A 3CCUE 1QVGE 3CCLE 1QVFE 4WFAE 5AN9B 3I56E 2ZJQE 2ZJPE 1YJWE 5H1SI 5GAHG 1VQ5E 1K8AG 4IO9E 1VQPE 1VQLE 3PIOE 3CMAE 3OW2E 3CCVE 5JVGE 1M90G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQK E;  3CF5 E;  1YI2 E;  4WFN E;  1Q86 G;  5DM7 E;  1YIT E;  1YIJ E;  4IOA E;  4WFB E;  2CQL A;  3J7Z G;  1VQO E;  5HL7 E;  3G71 E;  3CCR E;  4WCE E;  3I55 E;  1Q7Y G;  3CD6 E;  1YJN E;  5GAG G;  4IOC E;  1YJ9 E;  2QA4 E;  1W2B E;  1VQM E;  1VQ8 E;  4UY8 G;  2QEX E;  5DM6 E;  1M1K G;  3CCM E;  1JJ2 E;  4WF9 E;  3PIP E;  1S72 E;  1K73 G;  1KC8 G;  2OTL E;  3CCE E;  3CPW E;  3DLL E;  5JVH E;  2ZJR E;  1VQN E;  3CXC E;  1N8R G;  3G4S E;  3CC7 E;  1VQ7 E;  1K9M G;  1VQ4 E;  5GAE G;  1Q81 G;  1VQ9 E;  1VQ6 E;  5GAD G;  3CC2 E;  1NJI G;  1YHQ E;  1KQS E;  3CME E;  3CCJ E;  1KD1 G;  3CC4 E;  4U67 E;  3G6E E;  1Q82 G;  3CCQ E;  2OTJ E;  5MLC H;  3CCS E;  1RL6 A;  3CCU E;  1QVG E;  3CCL E;  1QVF E;  4WFA E;  5AN9 B;  3I56 E;  2ZJQ E;  2ZJP E;  1YJW E;  5H1S I;  5GAH G;  1VQ5 E;  1K8A G;  4IO9 E;  1VQP E;  1VQL E;  3PIO E;  3CMA E;  3OW2 E;  3CCV E;  5JVG E;  1M90 G; 
#chains in the Genus database with same CATH topology
 1VQK E;  3CF5 E;  1YI2 E;  4WFN E;  1Q86 G;  5DM7 E;  1YIT E;  1YIJ E;  4IOA E;  4WFB E;  2CQL A;  3J7Z G;  1VQO E;  2OY8 A;  5HL7 E;  3G71 E;  3CCR E;  4WCE E;  3I55 E;  1Q7Y G;  3CD6 E;  5GAG G;  1YJN E;  4IOC E;  1YJ9 E;  2QA4 E;  1W2B E;  3IGE A;  1VQM E;  1VQ8 E;  4UY8 G;  2QEX E;  1OSP O;  5DM6 E;  1P4P A;  3AUM O;  1M1K G;  2PI3 O;  3CCM E;  1JJ2 E;  2AF5 A;  4WF9 E;  5B10 O;  3PIP E;  1S72 E;  1K73 G;  1KC8 G;  2OTL E;  3CCE E;  3CPW E;  2I5Z O;  3DLL E;  5JVH E;  2ZJR E;  1VQN E;  2FKG A;  3CXC E;  3G4S E;  1N8R G;  3CC7 E;  1VQ7 E;  1K9M G;  1VQ4 E;  5GAE G;  5B3M O;  1Q81 G;  1VQ9 E;  1VQ6 E;  2FKJ A;  5GAD G;  3IG9 A;  3CC2 E;  1NJI G;  1YHQ E;  1KQS E;  3CME E;  3CCJ E;  1KD1 G;  3CC4 E;  2OL7 A;  2G8C O;  2I5V O;  1FJ1 E;  4U67 E;  3G6E E;  1Q82 G;  3CCQ E;  2OTJ E;  5MLC H;  3CCS E;  1RL6 A;  3CCU E;  3CKG A;  1QVG E;  3CCL E;  3CKF A;  1QVF E;  2OY7 A;  2OYB O;  4WFA E;  5AN9 B;  2OY1 O;  2OY5 O;  2OL8 O;  3I56 E;  2ZJQ E;  2ZJP E;  1YJW E;  3EC5 A;  5H1S I;  5GAH G;  1VQ5 E;  1RJL C;  1K8A G;  5B2A O;  5B11 O;  4IO9 E;  1VQP E;  1VQL E;  3PIO E;  3CMA E;  3OW2 E;  3CCV E;  5JVG E;  1M90 G;  2OL6 O;  2HKD A; 
#chains in the Genus database with same CATH homology
 1VQK E;  3CF5 E;  1YI2 E;  4WFN E;  1Q86 G;  5DM7 E;  1YIT E;  1YIJ E;  4IOA E;  4WFB E;  2CQL A;  3J7Z G;  1VQO E;  5HL7 E;  3G71 E;  3CCR E;  4WCE E;  3I55 E;  1Q7Y G;  3CD6 E;  1YJN E;  5GAG G;  4IOC E;  1YJ9 E;  2QA4 E;  1W2B E;  1VQM E;  1VQ8 E;  4UY8 G;  2QEX E;  5DM6 E;  1M1K G;  3CCM E;  1JJ2 E;  4WF9 E;  3PIP E;  1S72 E;  1K73 G;  1KC8 G;  2OTL E;  3CCE E;  3CPW E;  3DLL E;  5JVH E;  2ZJR E;  1VQN E;  3CXC E;  1N8R G;  3G4S E;  3CC7 E;  1VQ7 E;  1K9M G;  1VQ4 E;  5GAE G;  1Q81 G;  1VQ9 E;  1VQ6 E;  5GAD G;  3CC2 E;  1NJI G;  1YHQ E;  1KQS E;  3CME E;  3CCJ E;  1KD1 G;  3CC4 E;  4U67 E;  3G6E E;  1Q82 G;  3CCQ E;  2OTJ E;  5MLC H;  3CCS E;  1RL6 A;  3CCU E;  1QVG E;  3CCL E;  1QVF E;  4WFA E;  5AN9 B;  3I56 E;  2ZJQ E;  2ZJP E;  1YJW E;  5H1S I;  5GAH G;  1VQ5 E;  1K8A G;  4IO9 E;  1VQP E;  1VQL E;  3PIO E;  3CMA E;  3OW2 E;  3CCV E;  5JVG E;  1M90 G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...