3G6EE

Co-crystal structure of homoharringtonine bound to the large ribosomal subunit
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 35
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2009-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3g6eE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3g6eE01
1VQ8E 3DLLE 1VQ7E 1QVFE 3CCQE 1M90G 5DM7E 1S72E 2QA4E 4IOAE 1VQME 4WF9E 3G71E 3CC7E 3CCUE 5GADG 5JVGE 3CCVE 1NJIG 4WCEE 2OTLE 1VQLE 1YJWE 1KC8G 3CCRE 3CF5E 3G4SE 1Q86G 1JJ2E 3CC2E 2ZJPE 3CXCE 2QEXE 3CMAE 3CCLE 1KD1G 1VQKE 2OTJE 4WFAE 4U67E 2CQLA 3CCSE 1VQ6E 3CC4E 3OW2E 1Q82G 1K8AG 3CD6E 4IO9E 1YJ9E 4WFBE 1Q7YG 5MLCH 1YJNE 1VQ9E 3CCME 1VQ4E 3J7ZG 1KQSE 1N8RG 1VQ5E 3CPWE 1K9MG 1VQNE 5DM6E 1VQPE 3G6EE 2ZJRE 1RL6A 3I56E 1YITE 4WFNE 5AN9B 1W2BE 1YIJE 5H1SI 1Q81G 3I55E 1VQOE 1QVGE 1YHQE 3CMEE 2ZJQE 3PIPE 1K73G 5GAHG 5JVHE 4IOCE 5GAGG 1YI2E 3CCJE 4UY8G 5HL7E 3CCEE 3PIOE 5GAEG 1M1KG
chains in the Genus database with same CATH superfamily
3IG9A 1VQ8E 3DLLE 1VQ7E 2FKGA 1QVFE 3CCQE 1M90G 5DM7E 2OY8A 1S72E 2QA4E 4IOAE 1VQME 4WF9E 3G71E 3CC7E 3CCUE 5GADG 5JVGE 3CCVE 1NJIG 4WCEE 1RJLC 2OTLE 1VQLE 1YJWE 1KC8G 2OL8O 3CCRE 3CF5E 3G4SE 1Q86G 1JJ2E 3CC2E 3AUMO 2OY7A 2ZJPE 3CXCE 2QEXE 3CMAE 3CCLE 1KD1G 1VQKE 2OTJE 4WFAE 4U67E 2HKDA 2CQLA 5B3MO 3CCSE 1VQ6E 2PI3O 3CC4E 3OW2E 2G8CO 3CKGA 3CKFA 1Q82G 1K8AG 3CD6E 4IO9E 1YJ9E 3IGEA 4WFBE 1Q7YG 5MLCH 1YJNE 1VQ9E 3CCME 1VQ4E 3J7ZG 1KQSE 1N8RG 1VQ5E 1FJ1E 3CPWE 1K9MG 1VQNE 2OYBO 5DM6E 1VQPE 5B10O 3G6EE 2ZJRE 1RL6A 3I56E 3EC5A 1OSPO 2OL6O 1YITE 4WFNE 1P4PA 2AF5A 2I5ZO 5AN9B 1W2BE 1YIJE 5H1SI 1Q81G 2FKJA 3I55E 1VQOE 1QVGE 1YHQE 2OY5O 5B2AO 5B11O 3CMEE 2ZJQE 3PIPE 1K73G 5GAHG 2I5VO 2OY1O 5JVHE 4IOCE 5GAGG 1YI2E 3CCJE 4UY8G 2OL7A 5HL7E 3CCEE 3PIOE 5GAEG 1M1KG
chains in the Genus database with same CATH topology
1VQ8E 3DLLE 1VQ7E 1QVFE 3CCQE 1M90G 5DM7E 1S72E 2QA4E 4IOAE 1VQME 4WF9E 3G71E 3CC7E 3CCUE 5GADG 5JVGE 3CCVE 1NJIG 4WCEE 2OTLE 1VQLE 1YJWE 1KC8G 3CCRE 3CF5E 3G4SE 1Q86G 1JJ2E 3CC2E 2ZJPE 3CXCE 2QEXE 3CMAE 3CCLE 1KD1G 1VQKE 2OTJE 4WFAE 4U67E 2CQLA 3CCSE 1VQ6E 3CC4E 3OW2E 1Q82G 1K8AG 3CD6E 4IO9E 1YJ9E 4WFBE 1Q7YG 5MLCH 1YJNE 1VQ9E 3CCME 1VQ4E 3J7ZG 1KQSE 1N8RG 1VQ5E 3CPWE 1K9MG 1VQNE 5DM6E 1VQPE 3G6EE 2ZJRE 1RL6A 3I56E 1YITE 4WFNE 5AN9B 1W2BE 1YIJE 5H1SI 1Q81G 3I55E 1VQOE 1QVGE 1YHQE 3CMEE 2ZJQE 3PIPE 1K73G 5GAHG 5JVHE 4IOCE 5GAGG 1YI2E 3CCJE 4UY8G 5HL7E 3CCEE 3PIOE 5GAEG 1M1KG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ8 E;  3DLL E;  1VQ7 E;  1QVF E;  3CCQ E;  1M90 G;  5DM7 E;  1S72 E;  2QA4 E;  4IOA E;  1VQM E;  4WF9 E;  3G71 E;  3CC7 E;  3CCU E;  5GAD G;  5JVG E;  3CCV E;  1NJI G;  4WCE E;  2OTL E;  1VQL E;  1YJW E;  1KC8 G;  3CCR E;  3CF5 E;  3G4S E;  1Q86 G;  1JJ2 E;  3CC2 E;  2ZJP E;  3CXC E;  2QEX E;  3CMA E;  3CCL E;  1KD1 G;  1VQK E;  2OTJ E;  4WFA E;  4U67 E;  2CQL A;  3CCS E;  1VQ6 E;  3CC4 E;  3OW2 E;  1Q82 G;  1K8A G;  3CD6 E;  4IO9 E;  1YJ9 E;  4WFB E;  1Q7Y G;  5MLC H;  1YJN E;  1VQ9 E;  3CCM E;  1VQ4 E;  3J7Z G;  1KQS E;  1N8R G;  1VQ5 E;  3CPW E;  1K9M G;  1VQN E;  5DM6 E;  1VQP E;  3G6E E;  2ZJR E;  1RL6 A;  3I56 E;  1YIT E;  4WFN E;  5AN9 B;  1W2B E;  1YIJ E;  5H1S I;  1Q81 G;  3I55 E;  1VQO E;  1QVG E;  1YHQ E;  3CME E;  2ZJQ E;  3PIP E;  1K73 G;  5GAH G;  5JVH E;  4IOC E;  5GAG G;  1YI2 E;  3CCJ E;  4UY8 G;  5HL7 E;  3CCE E;  3PIO E;  5GAE G;  1M1K G; 
#chains in the Genus database with same CATH topology
 3IG9 A;  1VQ8 E;  3DLL E;  1VQ7 E;  2FKG A;  1QVF E;  3CCQ E;  1M90 G;  5DM7 E;  2OY8 A;  1S72 E;  2QA4 E;  4IOA E;  1VQM E;  4WF9 E;  3G71 E;  3CC7 E;  3CCU E;  5GAD G;  5JVG E;  3CCV E;  1NJI G;  4WCE E;  1RJL C;  2OTL E;  1VQL E;  1YJW E;  1KC8 G;  2OL8 O;  3CCR E;  3CF5 E;  3G4S E;  1Q86 G;  1JJ2 E;  3CC2 E;  3AUM O;  2OY7 A;  2ZJP E;  3CXC E;  2QEX E;  3CMA E;  3CCL E;  1KD1 G;  1VQK E;  2OTJ E;  4WFA E;  4U67 E;  2HKD A;  2CQL A;  5B3M O;  3CCS E;  1VQ6 E;  2PI3 O;  3CC4 E;  3OW2 E;  2G8C O;  3CKG A;  3CKF A;  1Q82 G;  1K8A G;  3CD6 E;  4IO9 E;  1YJ9 E;  3IGE A;  4WFB E;  1Q7Y G;  5MLC H;  1YJN E;  1VQ9 E;  3CCM E;  1VQ4 E;  3J7Z G;  1KQS E;  1N8R G;  1VQ5 E;  1FJ1 E;  3CPW E;  1K9M G;  1VQN E;  2OYB O;  5DM6 E;  1VQP E;  5B10 O;  3G6E E;  2ZJR E;  1RL6 A;  3I56 E;  3EC5 A;  1OSP O;  2OL6 O;  1YIT E;  4WFN E;  1P4P A;  2AF5 A;  2I5Z O;  5AN9 B;  1W2B E;  1YIJ E;  5H1S I;  1Q81 G;  2FKJ A;  3I55 E;  1VQO E;  1QVG E;  1YHQ E;  2OY5 O;  5B2A O;  5B11 O;  3CME E;  2ZJQ E;  3PIP E;  1K73 G;  5GAH G;  2I5V O;  2OY1 O;  5JVH E;  4IOC E;  5GAG G;  1YI2 E;  3CCJ E;  4UY8 G;  2OL7 A;  5HL7 E;  3CCE E;  3PIO E;  5GAE G;  1M1K G; 
#chains in the Genus database with same CATH homology
 1VQ8 E;  3DLL E;  1VQ7 E;  1QVF E;  3CCQ E;  1M90 G;  5DM7 E;  1S72 E;  2QA4 E;  4IOA E;  1VQM E;  4WF9 E;  3G71 E;  3CC7 E;  3CCU E;  5GAD G;  5JVG E;  3CCV E;  1NJI G;  4WCE E;  2OTL E;  1VQL E;  1YJW E;  1KC8 G;  3CCR E;  3CF5 E;  3G4S E;  1Q86 G;  1JJ2 E;  3CC2 E;  2ZJP E;  3CXC E;  2QEX E;  3CMA E;  3CCL E;  1KD1 G;  1VQK E;  2OTJ E;  4WFA E;  4U67 E;  2CQL A;  3CCS E;  1VQ6 E;  3CC4 E;  3OW2 E;  1Q82 G;  1K8A G;  3CD6 E;  4IO9 E;  1YJ9 E;  4WFB E;  1Q7Y G;  5MLC H;  1YJN E;  1VQ9 E;  3CCM E;  1VQ4 E;  3J7Z G;  1KQS E;  1N8R G;  1VQ5 E;  3CPW E;  1K9M G;  1VQN E;  5DM6 E;  1VQP E;  3G6E E;  2ZJR E;  1RL6 A;  3I56 E;  1YIT E;  4WFN E;  5AN9 B;  1W2B E;  1YIJ E;  5H1S I;  1Q81 G;  3I55 E;  1VQO E;  1QVG E;  1YHQ E;  3CME E;  2ZJQ E;  3PIP E;  1K73 G;  5GAH G;  5JVH E;  4IOC E;  5GAG G;  1YI2 E;  3CCJ E;  4UY8 G;  5HL7 E;  3CCE E;  3PIO E;  5GAE G;  1M1K G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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