3PIOE

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 25
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pioE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pioE01
4WFAE 5DM7E 3PIOE 3CCSE 1VQ7E 3J7ZG 3OW2E 3CCLE 1KD1G 1YI2E 1Q7YG 3CXCE 5H1SI 1M1KG 3CCUE 2CQLA 1QVFE 1VQ5E 1VQNE 2QEXE 3CCEE 1VQME 2ZJPE 1Q86G 3CPWE 5MLCH 3CMAE 1K9MG 4IOAE 5HL7E 3CD6E 5JVGE 1KQSE 3CCVE 3CMEE 4IO9E 1YIJE 3CC2E 1K8AG 1VQ9E 4WFBE 5JVHE 3G6EE 1VQKE 4WF9E 2OTLE 1VQ4E 3I55E 5AN9B 3CCJE 4U67E 1JJ2E 1KC8G 1RL6A 2ZJRE 1VQ6E 1K73G 1W2BE 1S72E 4WFNE 1YJ9E 3CC4E 1VQLE 1VQPE 1VQOE 4UY8G 5DM6E 2ZJQE 5GAGG 2OTJE 5GAEG 3DLLE 1YHQE 3CCRE 1N8RG 1YJNE 1YITE 3CCME 3G4SE 3G71E 4WCEE 1NJIG 3CC7E 5GADG 4IOCE 2QA4E 1QVGE 3I56E 3CF5E 5GAHG 1Q82G 1Q81G 3CCQE 1M90G 1VQ8E 3PIPE 1YJWE
chains in the Genus database with same CATH superfamily
4WFAE 5DM7E 3PIOE 3CCSE 1VQ7E 3J7ZG 3OW2E 3CCLE 2OYBO 2OL7A 1YI2E 1KD1G 1Q7YG 2OY5O 3CXCE 2OL8O 5H1SI 1M1KG 3CCUE 2CQLA 1QVFE 1VQ5E 2G8CO 2QEXE 1VQNE 3CCEE 1VQME 2ZJPE 2OL6O 1Q86G 3CPWE 5MLCH 1FJ1E 3CMAE 1K9MG 3AUMO 4IOAE 5HL7E 3CD6E 2OY7A 2I5ZO 5JVGE 1KQSE 3CCVE 3CKGA 3CMEE 4IO9E 1YIJE 3CC2E 1K8AG 3CKFA 2OY1O 2PI3O 1VQ9E 4WFBE 5JVHE 3G6EE 1RJLC 1VQKE 4WF9E 2OY8A 2HKDA 2OTLE 1VQ4E 3I55E 2FKJA 5AN9B 1OSPO 3CCJE 4U67E 1JJ2E 1KC8G 1RL6A 5B3MO 2ZJRE 1VQ6E 5B11O 5B10O 1K73G 1W2BE 3IGEA 1S72E 5B2AO 4WFNE 1YJ9E 3CC4E 2AF5A 1VQLE 1VQPE 1VQOE 4UY8G 5DM6E 2ZJQE 5GAGG 2OTJE 5GAEG 3DLLE 1YHQE 3CCRE 1N8RG 3IG9A 1P4PA 1YJNE 1YITE 3CCME 3G4SE 3G71E 4WCEE 1NJIG 3CC7E 5GADG 4IOCE 2QA4E 3EC5A 1QVGE 3I56E 3CF5E 5GAHG 1Q82G 2FKGA 1Q81G 3CCQE 1M90G 1VQ8E 3PIPE 1YJWE 2I5VO
chains in the Genus database with same CATH topology
4WFAE 5DM7E 3PIOE 3CCSE 1VQ7E 3J7ZG 3OW2E 3CCLE 1KD1G 1YI2E 1Q7YG 3CXCE 5H1SI 1M1KG 3CCUE 2CQLA 1QVFE 1VQ5E 1VQNE 2QEXE 3CCEE 1VQME 2ZJPE 1Q86G 3CPWE 5MLCH 3CMAE 1K9MG 4IOAE 5HL7E 3CD6E 5JVGE 1KQSE 3CCVE 3CMEE 4IO9E 1YIJE 3CC2E 1K8AG 1VQ9E 4WFBE 5JVHE 3G6EE 1VQKE 4WF9E 2OTLE 1VQ4E 3I55E 5AN9B 3CCJE 4U67E 1JJ2E 1KC8G 1RL6A 2ZJRE 1VQ6E 1K73G 1W2BE 1S72E 4WFNE 1YJ9E 3CC4E 1VQLE 1VQPE 1VQOE 4UY8G 5DM6E 2ZJQE 5GAGG 2OTJE 5GAEG 3DLLE 1YHQE 3CCRE 1N8RG 1YJNE 1YITE 3CCME 3G4SE 3G71E 4WCEE 1NJIG 3CC7E 5GADG 4IOCE 2QA4E 1QVGE 3I56E 3CF5E 5GAHG 1Q82G 1Q81G 3CCQE 1M90G 1VQ8E 3PIPE 1YJWE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA E;  5DM7 E;  3PIO E;  3CCS E;  1VQ7 E;  3J7Z G;  3OW2 E;  3CCL E;  1KD1 G;  1YI2 E;  1Q7Y G;  3CXC E;  5H1S I;  1M1K G;  3CCU E;  2CQL A;  1QVF E;  1VQ5 E;  1VQN E;  2QEX E;  3CCE E;  1VQM E;  2ZJP E;  1Q86 G;  3CPW E;  5MLC H;  3CMA E;  1K9M G;  4IOA E;  5HL7 E;  3CD6 E;  5JVG E;  1KQS E;  3CCV E;  3CME E;  4IO9 E;  1YIJ E;  3CC2 E;  1K8A G;  1VQ9 E;  4WFB E;  5JVH E;  3G6E E;  1VQK E;  4WF9 E;  2OTL E;  1VQ4 E;  3I55 E;  5AN9 B;  3CCJ E;  4U67 E;  1JJ2 E;  1KC8 G;  1RL6 A;  2ZJR E;  1VQ6 E;  1K73 G;  1W2B E;  1S72 E;  4WFN E;  1YJ9 E;  3CC4 E;  1VQL E;  1VQP E;  1VQO E;  4UY8 G;  5DM6 E;  2ZJQ E;  5GAG G;  2OTJ E;  5GAE G;  3DLL E;  1YHQ E;  3CCR E;  1N8R G;  1YJN E;  1YIT E;  3CCM E;  3G4S E;  3G71 E;  4WCE E;  1NJI G;  3CC7 E;  5GAD G;  4IOC E;  2QA4 E;  1QVG E;  3I56 E;  3CF5 E;  5GAH G;  1Q82 G;  1Q81 G;  3CCQ E;  1M90 G;  1VQ8 E;  3PIP E;  1YJW E; 
#chains in the Genus database with same CATH topology
 4WFA E;  5DM7 E;  3PIO E;  3CCS E;  1VQ7 E;  3J7Z G;  3OW2 E;  3CCL E;  2OYB O;  2OL7 A;  1YI2 E;  1KD1 G;  1Q7Y G;  2OY5 O;  3CXC E;  2OL8 O;  5H1S I;  1M1K G;  3CCU E;  2CQL A;  1QVF E;  1VQ5 E;  2G8C O;  2QEX E;  1VQN E;  3CCE E;  1VQM E;  2ZJP E;  2OL6 O;  1Q86 G;  3CPW E;  5MLC H;  1FJ1 E;  3CMA E;  1K9M G;  3AUM O;  4IOA E;  5HL7 E;  3CD6 E;  2OY7 A;  2I5Z O;  5JVG E;  1KQS E;  3CCV E;  3CKG A;  3CME E;  4IO9 E;  1YIJ E;  3CC2 E;  1K8A G;  3CKF A;  2OY1 O;  2PI3 O;  1VQ9 E;  4WFB E;  5JVH E;  3G6E E;  1RJL C;  1VQK E;  4WF9 E;  2OY8 A;  2HKD A;  2OTL E;  1VQ4 E;  3I55 E;  2FKJ A;  5AN9 B;  1OSP O;  3CCJ E;  4U67 E;  1JJ2 E;  1KC8 G;  1RL6 A;  5B3M O;  2ZJR E;  1VQ6 E;  5B11 O;  5B10 O;  1K73 G;  1W2B E;  3IGE A;  1S72 E;  5B2A O;  4WFN E;  1YJ9 E;  3CC4 E;  2AF5 A;  1VQL E;  1VQP E;  1VQO E;  4UY8 G;  5DM6 E;  2ZJQ E;  5GAG G;  2OTJ E;  5GAE G;  3DLL E;  1YHQ E;  3CCR E;  1N8R G;  3IG9 A;  1P4P A;  1YJN E;  1YIT E;  3CCM E;  3G4S E;  3G71 E;  4WCE E;  1NJI G;  3CC7 E;  5GAD G;  4IOC E;  2QA4 E;  3EC5 A;  1QVG E;  3I56 E;  3CF5 E;  5GAH G;  1Q82 G;  2FKG A;  1Q81 G;  3CCQ E;  1M90 G;  1VQ8 E;  3PIP E;  1YJW E;  2I5V O; 
#chains in the Genus database with same CATH homology
 4WFA E;  5DM7 E;  3PIO E;  3CCS E;  1VQ7 E;  3J7Z G;  3OW2 E;  3CCL E;  1KD1 G;  1YI2 E;  1Q7Y G;  3CXC E;  5H1S I;  1M1K G;  3CCU E;  2CQL A;  1QVF E;  1VQ5 E;  1VQN E;  2QEX E;  3CCE E;  1VQM E;  2ZJP E;  1Q86 G;  3CPW E;  5MLC H;  3CMA E;  1K9M G;  4IOA E;  5HL7 E;  3CD6 E;  5JVG E;  1KQS E;  3CCV E;  3CME E;  4IO9 E;  1YIJ E;  3CC2 E;  1K8A G;  1VQ9 E;  4WFB E;  5JVH E;  3G6E E;  1VQK E;  4WF9 E;  2OTL E;  1VQ4 E;  3I55 E;  5AN9 B;  3CCJ E;  4U67 E;  1JJ2 E;  1KC8 G;  1RL6 A;  2ZJR E;  1VQ6 E;  1K73 G;  1W2B E;  1S72 E;  4WFN E;  1YJ9 E;  3CC4 E;  1VQL E;  1VQP E;  1VQO E;  4UY8 G;  5DM6 E;  2ZJQ E;  5GAG G;  2OTJ E;  5GAE G;  3DLL E;  1YHQ E;  3CCR E;  1N8R G;  1YJN E;  1YIT E;  3CCM E;  3G4S E;  3G71 E;  4WCE E;  1NJI G;  3CC7 E;  5GAD G;  4IOC E;  2QA4 E;  1QVG E;  3I56 E;  3CF5 E;  5GAH G;  1Q82 G;  1Q81 G;  3CCQ E;  1M90 G;  1VQ8 E;  3PIP E;  1YJW E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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