3PIPE

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 23
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pipE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pipE01
1K73G 4UY8G 3CXCE 3CPWE 2QA4E 4IOAE 1JJ2E 3CCRE 2ZJPE 3I56E 3CCUE 3CCLE 5MLCH 1VQKE 4U67E 5H1SI 3PIOE 4WFNE 3CMAE 3CC7E 1W2BE 1YJWE 4IO9E 5GAGG 3CCQE 3G6EE 1VQ7E 1KQSE 3G4SE 1YHQE 3CC4E 3CC2E 3CCME 2ZJQE 1KC8G 1VQME 1VQ5E 3CCJE 5JVGE 1YIJE 5AN9B 1M90G 4IOCE 5DM7E 3CCSE 1VQPE 1K8AG 1YJ9E 2CQLA 4WF9E 3G71E 3CF5E 1Q81G 1Q82G 1RL6A 1YI2E 1YJNE 1QVFE 4WCEE 1VQ9E 5HL7E 1YITE 1KD1G 1VQ8E 4WFBE 1Q86G 1S72E 1NJIG 3CCEE 3DLLE 1VQ4E 4WFAE 1VQLE 2OTLE 1K9MG 2OTJE 1VQOE 3CD6E 5GADG 5DM6E 2QEXE 1Q7YG 1VQ6E 2ZJRE 3CCVE 5GAHG 1M1KG 3CMEE 3I55E 3OW2E 1N8RG 1QVGE 5JVHE 3PIPE 1VQNE 5GAEG 3J7ZG
chains in the Genus database with same CATH superfamily
1K73G 4UY8G 3CXCE 3IG9A 3CPWE 2QA4E 4IOAE 1JJ2E 3CCRE 2ZJPE 3I56E 3CCUE 3AUMO 3CCLE 1RJLC 2OY1O 5MLCH 1VQKE 4U67E 2OYBO 5H1SI 2OL8O 3PIOE 4WFNE 3CMAE 3CC7E 1W2BE 1YJWE 4IO9E 5GAGG 2I5VO 2PI3O 3CCQE 3IGEA 2FKJA 3G6EE 1VQ7E 2OY5O 1KQSE 3G4SE 1YHQE 2OL7A 3CC4E 3CC2E 3CCME 2ZJQE 1KC8G 1VQME 3CKFA 1VQ5E 3CCJE 5JVGE 1YIJE 5AN9B 1M90G 4IOCE 5DM7E 3CCSE 1VQPE 1K8AG 1OSPO 1YJ9E 2CQLA 4WF9E 3G71E 5B3MO 3CF5E 1Q81G 1FJ1E 1Q82G 1RL6A 1YI2E 1YJNE 1QVFE 4WCEE 1VQ9E 5HL7E 2I5ZO 1YITE 1KD1G 2HKDA 2OY8A 1VQ8E 4WFBE 1Q86G 1S72E 1NJIG 3CCEE 2OL6O 3EC5A 2G8CO 3DLLE 1VQ4E 4WFAE 1VQLE 2OTLE 3CKGA 1K9MG 2OTJE 1VQOE 3CD6E 5B11O 5B2AO 5GADG 5DM6E 2QEXE 1Q7YG 1VQ6E 2ZJRE 3CCVE 5GAHG 1M1KG 3CMEE 3I55E 3OW2E 2OY7A 1N8RG 2FKGA 1QVGE 2AF5A 5JVHE 1P4PA 3PIPE 5B10O 1VQNE 5GAEG 3J7ZG
chains in the Genus database with same CATH topology
1K73G 4UY8G 3CXCE 3CPWE 2QA4E 4IOAE 1JJ2E 3CCRE 2ZJPE 3I56E 3CCUE 3CCLE 5MLCH 1VQKE 4U67E 5H1SI 3PIOE 4WFNE 3CMAE 3CC7E 1W2BE 1YJWE 4IO9E 5GAGG 3CCQE 3G6EE 1VQ7E 1KQSE 3G4SE 1YHQE 3CC4E 3CC2E 3CCME 2ZJQE 1KC8G 1VQME 1VQ5E 3CCJE 5JVGE 1YIJE 5AN9B 1M90G 4IOCE 5DM7E 3CCSE 1VQPE 1K8AG 1YJ9E 2CQLA 4WF9E 3G71E 3CF5E 1Q81G 1Q82G 1RL6A 1YI2E 1YJNE 1QVFE 4WCEE 1VQ9E 5HL7E 1YITE 1KD1G 1VQ8E 4WFBE 1Q86G 1S72E 1NJIG 3CCEE 3DLLE 1VQ4E 4WFAE 1VQLE 2OTLE 1K9MG 2OTJE 1VQOE 3CD6E 5GADG 5DM6E 2QEXE 1Q7YG 1VQ6E 2ZJRE 3CCVE 5GAHG 1M1KG 3CMEE 3I55E 3OW2E 1N8RG 1QVGE 5JVHE 3PIPE 1VQNE 5GAEG 3J7ZG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K73 G;  4UY8 G;  3CXC E;  3CPW E;  2QA4 E;  4IOA E;  1JJ2 E;  3CCR E;  2ZJP E;  3I56 E;  3CCU E;  3CCL E;  5MLC H;  1VQK E;  4U67 E;  5H1S I;  3PIO E;  4WFN E;  3CMA E;  3CC7 E;  1W2B E;  1YJW E;  4IO9 E;  5GAG G;  3CCQ E;  3G6E E;  1VQ7 E;  1KQS E;  3G4S E;  1YHQ E;  3CC4 E;  3CC2 E;  3CCM E;  2ZJQ E;  1KC8 G;  1VQM E;  1VQ5 E;  3CCJ E;  5JVG E;  1YIJ E;  5AN9 B;  1M90 G;  4IOC E;  5DM7 E;  3CCS E;  1VQP E;  1K8A G;  1YJ9 E;  2CQL A;  4WF9 E;  3G71 E;  3CF5 E;  1Q81 G;  1Q82 G;  1RL6 A;  1YI2 E;  1YJN E;  1QVF E;  4WCE E;  1VQ9 E;  5HL7 E;  1YIT E;  1KD1 G;  1VQ8 E;  4WFB E;  1Q86 G;  1S72 E;  1NJI G;  3CCE E;  3DLL E;  1VQ4 E;  4WFA E;  1VQL E;  2OTL E;  1K9M G;  2OTJ E;  1VQO E;  3CD6 E;  5GAD G;  5DM6 E;  2QEX E;  1Q7Y G;  1VQ6 E;  2ZJR E;  3CCV E;  5GAH G;  1M1K G;  3CME E;  3I55 E;  3OW2 E;  1N8R G;  1QVG E;  5JVH E;  3PIP E;  1VQN E;  5GAE G;  3J7Z G; 
#chains in the Genus database with same CATH topology
 1K73 G;  4UY8 G;  3CXC E;  3IG9 A;  3CPW E;  2QA4 E;  4IOA E;  1JJ2 E;  3CCR E;  2ZJP E;  3I56 E;  3CCU E;  3AUM O;  3CCL E;  1RJL C;  2OY1 O;  5MLC H;  1VQK E;  4U67 E;  2OYB O;  5H1S I;  2OL8 O;  3PIO E;  4WFN E;  3CMA E;  3CC7 E;  1W2B E;  1YJW E;  4IO9 E;  5GAG G;  2I5V O;  2PI3 O;  3CCQ E;  3IGE A;  2FKJ A;  3G6E E;  1VQ7 E;  2OY5 O;  1KQS E;  3G4S E;  1YHQ E;  2OL7 A;  3CC4 E;  3CC2 E;  3CCM E;  2ZJQ E;  1KC8 G;  1VQM E;  3CKF A;  1VQ5 E;  3CCJ E;  5JVG E;  1YIJ E;  5AN9 B;  1M90 G;  4IOC E;  5DM7 E;  3CCS E;  1VQP E;  1K8A G;  1OSP O;  1YJ9 E;  2CQL A;  4WF9 E;  3G71 E;  5B3M O;  3CF5 E;  1Q81 G;  1FJ1 E;  1Q82 G;  1RL6 A;  1YI2 E;  1YJN E;  1QVF E;  4WCE E;  1VQ9 E;  5HL7 E;  2I5Z O;  1YIT E;  1KD1 G;  2HKD A;  2OY8 A;  1VQ8 E;  4WFB E;  1Q86 G;  1S72 E;  1NJI G;  3CCE E;  2OL6 O;  3EC5 A;  2G8C O;  3DLL E;  1VQ4 E;  4WFA E;  1VQL E;  2OTL E;  3CKG A;  1K9M G;  2OTJ E;  1VQO E;  3CD6 E;  5B11 O;  5B2A O;  5GAD G;  5DM6 E;  2QEX E;  1Q7Y G;  1VQ6 E;  2ZJR E;  3CCV E;  5GAH G;  1M1K G;  3CME E;  3I55 E;  3OW2 E;  2OY7 A;  1N8R G;  2FKG A;  1QVG E;  2AF5 A;  5JVH E;  1P4P A;  3PIP E;  5B10 O;  1VQN E;  5GAE G;  3J7Z G; 
#chains in the Genus database with same CATH homology
 1K73 G;  4UY8 G;  3CXC E;  3CPW E;  2QA4 E;  4IOA E;  1JJ2 E;  3CCR E;  2ZJP E;  3I56 E;  3CCU E;  3CCL E;  5MLC H;  1VQK E;  4U67 E;  5H1S I;  3PIO E;  4WFN E;  3CMA E;  3CC7 E;  1W2B E;  1YJW E;  4IO9 E;  5GAG G;  3CCQ E;  3G6E E;  1VQ7 E;  1KQS E;  3G4S E;  1YHQ E;  3CC4 E;  3CC2 E;  3CCM E;  2ZJQ E;  1KC8 G;  1VQM E;  1VQ5 E;  3CCJ E;  5JVG E;  1YIJ E;  5AN9 B;  1M90 G;  4IOC E;  5DM7 E;  3CCS E;  1VQP E;  1K8A G;  1YJ9 E;  2CQL A;  4WF9 E;  3G71 E;  3CF5 E;  1Q81 G;  1Q82 G;  1RL6 A;  1YI2 E;  1YJN E;  1QVF E;  4WCE E;  1VQ9 E;  5HL7 E;  1YIT E;  1KD1 G;  1VQ8 E;  4WFB E;  1Q86 G;  1S72 E;  1NJI G;  3CCE E;  3DLL E;  1VQ4 E;  4WFA E;  1VQL E;  2OTL E;  1K9M G;  2OTJ E;  1VQO E;  3CD6 E;  5GAD G;  5DM6 E;  2QEX E;  1Q7Y G;  1VQ6 E;  2ZJR E;  3CCV E;  5GAH G;  1M1K G;  3CME E;  3I55 E;  3OW2 E;  1N8R G;  1QVG E;  5JVH E;  3PIP E;  1VQN E;  5GAE G;  3J7Z G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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