3CC4E

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 36
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc4E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc4E01
3CCLE 3CMAE 5MLCH 2QA4E 1YJWE 3I56E 1VQ8E 5GADG 5DM6E 1VQ7E 3CCJE 3J7ZG 2QEXE 3CCVE 4IOAE 3CCQE 1VQ4E 1YIJE 2ZJRE 5JVHE 3CCSE 1VQME 3CC2E 4UY8G 2ZJPE 4WFBE 1VQPE 5DM7E 3OW2E 3CMEE 1S72E 4WCEE 1N8RG 1Q81G 4U67E 3G6EE 5GAHG 4WF9E 1W2BE 1Q86G 1K8AG 3G71E 1M1KG 3CPWE 1NJIG 1KQSE 4IOCE 1VQ9E 3CCRE 3CCUE 3CCEE 2ZJQE 1Q82G 5H1SI 1YI2E 1YJ9E 1VQKE 5AN9B 5GAEG 1VQNE 3PIOE 3CXCE 1VQ6E 1RL6A 1VQOE 1K73G 2OTJE 3CCME 3I55E 1QVGE 3CC4E 1YHQE 1K9MG 3G4SE 4WFAE 1YJNE 1Q7YG 3CC7E 3PIPE 1KD1G 5JVGE 4IO9E 2CQLA 1YITE 1VQ5E 5HL7E 1VQLE 1KC8G 3DLLE 1QVFE 3CF5E 1M90G 5GAGG 1JJ2E 2OTLE 3CD6E 4WFNE
chains in the Genus database with same CATH superfamily
3CCLE 1P4PA 3CMAE 5MLCH 2QA4E 1YJWE 3I56E 1VQ8E 5GADG 5DM6E 1VQ7E 3CCJE 3J7ZG 2QEXE 3CCVE 3IG9A 2OL8O 2OL7A 3CKGA 4IOAE 3CCQE 1VQ4E 1YIJE 1OSPO 2ZJRE 5JVHE 3CCSE 1VQME 3CC2E 4UY8G 2OY1O 2ZJPE 2FKGA 2OL6O 4WFBE 1VQPE 3CKFA 5DM7E 3OW2E 2I5ZO 3CMEE 1S72E 1FJ1E 4WCEE 1N8RG 1Q81G 3AUMO 2OYBO 4U67E 5GAHG 3G6EE 4WF9E 1W2BE 1Q86G 1K8AG 3G71E 1M1KG 3CPWE 1NJIG 1RJLC 1KQSE 4IOCE 1VQ9E 3CCRE 3CCUE 2I5VO 2OY5O 3CCEE 3IGEA 2ZJQE 1Q82G 5H1SI 1YI2E 1YJ9E 1VQKE 5AN9B 5GAEG 5B11O 1VQNE 2G8CO 3PIOE 3CXCE 1VQ6E 2OY8A 1RL6A 1VQOE 1K73G 2OTJE 2PI3O 3CCME 3I55E 1QVGE 3CC4E 1YHQE 1K9MG 3G4SE 2OY7A 4WFAE 2FKJA 1YJNE 1Q7YG 5B3MO 3EC5A 5B10O 3CC7E 3PIPE 1KD1G 5JVGE 4IO9E 5B2AO 2CQLA 1YITE 1VQ5E 5HL7E 1VQLE 1KC8G 2HKDA 3DLLE 1QVFE 3CF5E 1M90G 5GAGG 1JJ2E 2OTLE 3CD6E 2AF5A 4WFNE
chains in the Genus database with same CATH topology
3CCLE 3CMAE 5MLCH 2QA4E 1YJWE 3I56E 1VQ8E 5GADG 5DM6E 1VQ7E 3CCJE 3J7ZG 2QEXE 3CCVE 4IOAE 3CCQE 1VQ4E 1YIJE 2ZJRE 5JVHE 3CCSE 1VQME 3CC2E 4UY8G 2ZJPE 4WFBE 1VQPE 5DM7E 3OW2E 3CMEE 1S72E 4WCEE 1N8RG 1Q81G 4U67E 3G6EE 5GAHG 4WF9E 1W2BE 1Q86G 1K8AG 3G71E 1M1KG 3CPWE 1NJIG 1KQSE 4IOCE 1VQ9E 3CCRE 3CCUE 3CCEE 2ZJQE 1Q82G 5H1SI 1YI2E 1YJ9E 1VQKE 5AN9B 5GAEG 1VQNE 3PIOE 3CXCE 1VQ6E 1RL6A 1VQOE 1K73G 2OTJE 3CCME 3I55E 1QVGE 3CC4E 1YHQE 1K9MG 3G4SE 4WFAE 1YJNE 1Q7YG 3CC7E 3PIPE 1KD1G 5JVGE 4IO9E 2CQLA 1YITE 1VQ5E 5HL7E 1VQLE 1KC8G 3DLLE 1QVFE 3CF5E 1M90G 5GAGG 1JJ2E 2OTLE 3CD6E 4WFNE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCL E;  3CMA E;  5MLC H;  2QA4 E;  1YJW E;  3I56 E;  1VQ8 E;  5GAD G;  5DM6 E;  1VQ7 E;  3CCJ E;  3J7Z G;  2QEX E;  3CCV E;  4IOA E;  3CCQ E;  1VQ4 E;  1YIJ E;  2ZJR E;  5JVH E;  3CCS E;  1VQM E;  3CC2 E;  4UY8 G;  2ZJP E;  4WFB E;  1VQP E;  5DM7 E;  3OW2 E;  3CME E;  1S72 E;  4WCE E;  1N8R G;  1Q81 G;  4U67 E;  3G6E E;  5GAH G;  4WF9 E;  1W2B E;  1Q86 G;  1K8A G;  3G71 E;  1M1K G;  3CPW E;  1NJI G;  1KQS E;  4IOC E;  1VQ9 E;  3CCR E;  3CCU E;  3CCE E;  2ZJQ E;  1Q82 G;  5H1S I;  1YI2 E;  1YJ9 E;  1VQK E;  5AN9 B;  5GAE G;  1VQN E;  3PIO E;  3CXC E;  1VQ6 E;  1RL6 A;  1VQO E;  1K73 G;  2OTJ E;  3CCM E;  3I55 E;  1QVG E;  3CC4 E;  1YHQ E;  1K9M G;  3G4S E;  4WFA E;  1YJN E;  1Q7Y G;  3CC7 E;  3PIP E;  1KD1 G;  5JVG E;  4IO9 E;  2CQL A;  1YIT E;  1VQ5 E;  5HL7 E;  1VQL E;  1KC8 G;  3DLL E;  1QVF E;  3CF5 E;  1M90 G;  5GAG G;  1JJ2 E;  2OTL E;  3CD6 E;  4WFN E; 
#chains in the Genus database with same CATH topology
 3CCL E;  1P4P A;  3CMA E;  5MLC H;  2QA4 E;  1YJW E;  3I56 E;  1VQ8 E;  5GAD G;  5DM6 E;  1VQ7 E;  3CCJ E;  3J7Z G;  2QEX E;  3CCV E;  3IG9 A;  2OL8 O;  2OL7 A;  3CKG A;  4IOA E;  3CCQ E;  1VQ4 E;  1YIJ E;  1OSP O;  2ZJR E;  5JVH E;  3CCS E;  1VQM E;  3CC2 E;  4UY8 G;  2OY1 O;  2ZJP E;  2FKG A;  2OL6 O;  4WFB E;  1VQP E;  3CKF A;  5DM7 E;  3OW2 E;  2I5Z O;  3CME E;  1S72 E;  1FJ1 E;  4WCE E;  1N8R G;  1Q81 G;  3AUM O;  2OYB O;  4U67 E;  5GAH G;  3G6E E;  4WF9 E;  1W2B E;  1Q86 G;  1K8A G;  3G71 E;  1M1K G;  3CPW E;  1NJI G;  1RJL C;  1KQS E;  4IOC E;  1VQ9 E;  3CCR E;  3CCU E;  2I5V O;  2OY5 O;  3CCE E;  3IGE A;  2ZJQ E;  1Q82 G;  5H1S I;  1YI2 E;  1YJ9 E;  1VQK E;  5AN9 B;  5GAE G;  5B11 O;  1VQN E;  2G8C O;  3PIO E;  3CXC E;  1VQ6 E;  2OY8 A;  1RL6 A;  1VQO E;  1K73 G;  2OTJ E;  2PI3 O;  3CCM E;  3I55 E;  1QVG E;  3CC4 E;  1YHQ E;  1K9M G;  3G4S E;  2OY7 A;  4WFA E;  2FKJ A;  1YJN E;  1Q7Y G;  5B3M O;  3EC5 A;  5B10 O;  3CC7 E;  3PIP E;  1KD1 G;  5JVG E;  4IO9 E;  5B2A O;  2CQL A;  1YIT E;  1VQ5 E;  5HL7 E;  1VQL E;  1KC8 G;  2HKD A;  3DLL E;  1QVF E;  3CF5 E;  1M90 G;  5GAG G;  1JJ2 E;  2OTL E;  3CD6 E;  2AF5 A;  4WFN E; 
#chains in the Genus database with same CATH homology
 3CCL E;  3CMA E;  5MLC H;  2QA4 E;  1YJW E;  3I56 E;  1VQ8 E;  5GAD G;  5DM6 E;  1VQ7 E;  3CCJ E;  3J7Z G;  2QEX E;  3CCV E;  4IOA E;  3CCQ E;  1VQ4 E;  1YIJ E;  2ZJR E;  5JVH E;  3CCS E;  1VQM E;  3CC2 E;  4UY8 G;  2ZJP E;  4WFB E;  1VQP E;  5DM7 E;  3OW2 E;  3CME E;  1S72 E;  4WCE E;  1N8R G;  1Q81 G;  4U67 E;  3G6E E;  5GAH G;  4WF9 E;  1W2B E;  1Q86 G;  1K8A G;  3G71 E;  1M1K G;  3CPW E;  1NJI G;  1KQS E;  4IOC E;  1VQ9 E;  3CCR E;  3CCU E;  3CCE E;  2ZJQ E;  1Q82 G;  5H1S I;  1YI2 E;  1YJ9 E;  1VQK E;  5AN9 B;  5GAE G;  1VQN E;  3PIO E;  3CXC E;  1VQ6 E;  1RL6 A;  1VQO E;  1K73 G;  2OTJ E;  3CCM E;  3I55 E;  1QVG E;  3CC4 E;  1YHQ E;  1K9M G;  3G4S E;  4WFA E;  1YJN E;  1Q7Y G;  3CC7 E;  3PIP E;  1KD1 G;  5JVG E;  4IO9 E;  2CQL A;  1YIT E;  1VQ5 E;  5HL7 E;  1VQL E;  1KC8 G;  3DLL E;  1QVF E;  3CF5 E;  1M90 G;  5GAG G;  1JJ2 E;  2OTL E;  3CD6 E;  4WFN E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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