3CC7E

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc7E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cc7E01
1VQ9E 3PIOE 3CMAE 1Q81G 1W2BE 3CC4E 1KQSE 5GAGG 2ZJQE 3CF5E 1VQ6E 1M1KG 2CQLA 3CCEE 3CPWE 2ZJPE 3G4SE 3CMEE 1S72E 3CCME 3CCUE 1VQOE 5JVGE 1VQNE 5GAHG 5DM7E 1NJIG 1VQ7E 1K9MG 2ZJRE 1YJ9E 1VQME 3DLLE 1YJWE 4WFBE 3G71E 1VQPE 1YI2E 3CD6E 5HL7E 3PIPE 1YITE 2OTLE 3OW2E 1VQ4E 1QVGE 1K8AG 3CC7E 5AN9B 4IOAE 3CCJE 1K73G 4WFAE 1Q86G 1Q7YG 3G6EE 3CCSE 4IOCE 3CCQE 1KD1G 5GADG 1VQLE 4WF9E 1N8RG 5MLCH 1KC8G 4IO9E 4WFNE 2QA4E 3I55E 1QVFE 5JVHE 1Q82G 5H1SI 4U67E 1VQ8E 3I56E 1YHQE 4WCEE 2QEXE 1VQKE 2OTJE 1YJNE 3CXCE 4UY8G 3CCRE 3J7ZG 1M90G 3CCVE 1YIJE 3CCLE 1RL6A 5GAEG 3CC2E 5DM6E 1JJ2E 1VQ5E
chains in the Genus database with same CATH superfamily
1VQ9E 3PIOE 3CMAE 1Q81G 3IGEA 2FKGA 1W2BE 2OY7A 3CC4E 1KQSE 5GAGG 2ZJQE 3CF5E 1VQ6E 3EC5A 1M1KG 2CQLA 3CCEE 3CPWE 2ZJPE 3G4SE 3CMEE 1S72E 3CCME 3CCUE 1VQOE 5JVGE 1VQNE 2I5ZO 3IG9A 5GAHG 5DM7E 1NJIG 2PI3O 1VQ7E 1K9MG 2G8CO 5B11O 2ZJRE 1OSPO 1YJ9E 1VQME 3DLLE 1YJWE 4WFBE 1FJ1E 3G71E 1VQPE 2OY1O 1YI2E 3CD6E 5HL7E 3PIPE 1YITE 2OTLE 3OW2E 1VQ4E 1QVGE 1K8AG 3CC7E 5B10O 2I5VO 5AN9B 3CKFA 2OL6O 2OL7A 3CCJE 4IOAE 1K73G 4WFAE 1Q86G 2OY5O 1Q7YG 3G6EE 3CCSE 4IOCE 3CCQE 1KD1G 5GADG 1VQLE 2OY8A 4WF9E 1N8RG 5MLCH 1KC8G 4IO9E 4WFNE 2QA4E 2AF5A 2OYBO 3I55E 1QVFE 5JVHE 1Q82G 5H1SI 4U67E 1VQ8E 3I56E 1P4PA 1YHQE 4WCEE 2QEXE 3CKGA 1VQKE 2OTJE 1YJNE 3CXCE 5B2AO 4UY8G 3CCRE 2OL8O 3J7ZG 1M90G 3CCVE 1RJLC 1YIJE 3CCLE 1RL6A 5GAEG 3CC2E 5DM6E 2FKJA 1JJ2E 3AUMO 2HKDA 1VQ5E 5B3MO
chains in the Genus database with same CATH topology
1VQ9E 3PIOE 3CMAE 1Q81G 1W2BE 3CC4E 1KQSE 5GAGG 2ZJQE 3CF5E 1VQ6E 1M1KG 2CQLA 3CCEE 3CPWE 2ZJPE 3G4SE 3CMEE 1S72E 3CCME 3CCUE 1VQOE 5JVGE 1VQNE 5GAHG 5DM7E 1NJIG 1VQ7E 1K9MG 2ZJRE 1YJ9E 1VQME 3DLLE 1YJWE 4WFBE 3G71E 1VQPE 1YI2E 3CD6E 5HL7E 3PIPE 1YITE 2OTLE 3OW2E 1VQ4E 1QVGE 1K8AG 3CC7E 5AN9B 4IOAE 3CCJE 1K73G 4WFAE 1Q86G 1Q7YG 3G6EE 3CCSE 4IOCE 3CCQE 1KD1G 5GADG 1VQLE 4WF9E 1N8RG 5MLCH 1KC8G 4IO9E 4WFNE 2QA4E 3I55E 1QVFE 5JVHE 1Q82G 5H1SI 4U67E 1VQ8E 3I56E 1YHQE 4WCEE 2QEXE 1VQKE 2OTJE 1YJNE 3CXCE 4UY8G 3CCRE 3J7ZG 1M90G 3CCVE 1YIJE 3CCLE 1RL6A 5GAEG 3CC2E 5DM6E 1JJ2E 1VQ5E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ9 E;  3PIO E;  3CMA E;  1Q81 G;  1W2B E;  3CC4 E;  1KQS E;  5GAG G;  2ZJQ E;  3CF5 E;  1VQ6 E;  1M1K G;  2CQL A;  3CCE E;  3CPW E;  2ZJP E;  3G4S E;  3CME E;  1S72 E;  3CCM E;  3CCU E;  1VQO E;  5JVG E;  1VQN E;  5GAH G;  5DM7 E;  1NJI G;  1VQ7 E;  1K9M G;  2ZJR E;  1YJ9 E;  1VQM E;  3DLL E;  1YJW E;  4WFB E;  3G71 E;  1VQP E;  1YI2 E;  3CD6 E;  5HL7 E;  3PIP E;  1YIT E;  2OTL E;  3OW2 E;  1VQ4 E;  1QVG E;  1K8A G;  3CC7 E;  5AN9 B;  4IOA E;  3CCJ E;  1K73 G;  4WFA E;  1Q86 G;  1Q7Y G;  3G6E E;  3CCS E;  4IOC E;  3CCQ E;  1KD1 G;  5GAD G;  1VQL E;  4WF9 E;  1N8R G;  5MLC H;  1KC8 G;  4IO9 E;  4WFN E;  2QA4 E;  3I55 E;  1QVF E;  5JVH E;  1Q82 G;  5H1S I;  4U67 E;  1VQ8 E;  3I56 E;  1YHQ E;  4WCE E;  2QEX E;  1VQK E;  2OTJ E;  1YJN E;  3CXC E;  4UY8 G;  3CCR E;  3J7Z G;  1M90 G;  3CCV E;  1YIJ E;  3CCL E;  1RL6 A;  5GAE G;  3CC2 E;  5DM6 E;  1JJ2 E;  1VQ5 E; 
#chains in the Genus database with same CATH topology
 1VQ9 E;  3PIO E;  3CMA E;  1Q81 G;  3IGE A;  2FKG A;  1W2B E;  2OY7 A;  3CC4 E;  1KQS E;  5GAG G;  2ZJQ E;  3CF5 E;  1VQ6 E;  3EC5 A;  1M1K G;  2CQL A;  3CCE E;  3CPW E;  2ZJP E;  3G4S E;  3CME E;  1S72 E;  3CCM E;  3CCU E;  1VQO E;  5JVG E;  1VQN E;  2I5Z O;  3IG9 A;  5GAH G;  5DM7 E;  1NJI G;  2PI3 O;  1VQ7 E;  1K9M G;  2G8C O;  5B11 O;  2ZJR E;  1OSP O;  1YJ9 E;  1VQM E;  3DLL E;  1YJW E;  4WFB E;  1FJ1 E;  3G71 E;  1VQP E;  2OY1 O;  1YI2 E;  3CD6 E;  5HL7 E;  3PIP E;  1YIT E;  2OTL E;  3OW2 E;  1VQ4 E;  1QVG E;  1K8A G;  3CC7 E;  5B10 O;  2I5V O;  5AN9 B;  3CKF A;  2OL6 O;  2OL7 A;  3CCJ E;  4IOA E;  1K73 G;  4WFA E;  1Q86 G;  2OY5 O;  1Q7Y G;  3G6E E;  3CCS E;  4IOC E;  3CCQ E;  1KD1 G;  5GAD G;  1VQL E;  2OY8 A;  4WF9 E;  1N8R G;  5MLC H;  1KC8 G;  4IO9 E;  4WFN E;  2QA4 E;  2AF5 A;  2OYB O;  3I55 E;  1QVF E;  5JVH E;  1Q82 G;  5H1S I;  4U67 E;  1VQ8 E;  3I56 E;  1P4P A;  1YHQ E;  4WCE E;  2QEX E;  3CKG A;  1VQK E;  2OTJ E;  1YJN E;  3CXC E;  5B2A O;  4UY8 G;  3CCR E;  2OL8 O;  3J7Z G;  1M90 G;  3CCV E;  1RJL C;  1YIJ E;  3CCL E;  1RL6 A;  5GAE G;  3CC2 E;  5DM6 E;  2FKJ A;  1JJ2 E;  3AUM O;  2HKD A;  1VQ5 E;  5B3M O; 
#chains in the Genus database with same CATH homology
 1VQ9 E;  3PIO E;  3CMA E;  1Q81 G;  1W2B E;  3CC4 E;  1KQS E;  5GAG G;  2ZJQ E;  3CF5 E;  1VQ6 E;  1M1K G;  2CQL A;  3CCE E;  3CPW E;  2ZJP E;  3G4S E;  3CME E;  1S72 E;  3CCM E;  3CCU E;  1VQO E;  5JVG E;  1VQN E;  5GAH G;  5DM7 E;  1NJI G;  1VQ7 E;  1K9M G;  2ZJR E;  1YJ9 E;  1VQM E;  3DLL E;  1YJW E;  4WFB E;  3G71 E;  1VQP E;  1YI2 E;  3CD6 E;  5HL7 E;  3PIP E;  1YIT E;  2OTL E;  3OW2 E;  1VQ4 E;  1QVG E;  1K8A G;  3CC7 E;  5AN9 B;  4IOA E;  3CCJ E;  1K73 G;  4WFA E;  1Q86 G;  1Q7Y G;  3G6E E;  3CCS E;  4IOC E;  3CCQ E;  1KD1 G;  5GAD G;  1VQL E;  4WF9 E;  1N8R G;  5MLC H;  1KC8 G;  4IO9 E;  4WFN E;  2QA4 E;  3I55 E;  1QVF E;  5JVH E;  1Q82 G;  5H1S I;  4U67 E;  1VQ8 E;  3I56 E;  1YHQ E;  4WCE E;  2QEX E;  1VQK E;  2OTJ E;  1YJN E;  3CXC E;  4UY8 G;  3CCR E;  3J7Z G;  1M90 G;  3CCV E;  1YIJ E;  3CCL E;  1RL6 A;  5GAE G;  3CC2 E;  5DM6 E;  1JJ2 E;  1VQ5 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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