3CCEE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cceE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cceE01
3CCSE 5JVHE 4WF9E 1NJIG 5GAEG 1VQLE 4UY8G 1YI2E 1K73G 3J7ZG 4WCEE 3OW2E 1S72E 1K8AG 3CC4E 3CCRE 1RL6A 1YJWE 3PIPE 5AN9B 1KQSE 5DM7E 1VQ7E 3CMEE 3PIOE 3CCLE 5MLCH 4IO9E 3CCEE 1YJNE 1VQ6E 2QEXE 1W2BE 1VQNE 1N8RG 3G6EE 1VQ4E 2ZJQE 1YITE 3CXCE 3CCQE 1Q86G 1KC8G 3I56E 5DM6E 3G4SE 1JJ2E 1Q81G 4IOCE 5GAHG 4WFNE 3CD6E 2OTLE 5GADG 5GAGG 2ZJRE 5HL7E 1KD1G 3DLLE 2OTJE 3CC7E 1Q82G 4WFBE 4U67E 1M1KG 1M90G 1VQ8E 1QVFE 1Q7YG 1VQ9E 3CMAE 1VQME 3I55E 1VQ5E 4IOAE 3CC2E 3CCME 1VQOE 3CCVE 3CF5E 3CPWE 5H1SI 1YHQE 5JVGE 2QA4E 1QVGE 1YJ9E 3CCUE 2CQLA 3CCJE 1VQPE 1YIJE 3G71E 1K9MG 2ZJPE 4WFAE 1VQKE
chains in the Genus database with same CATH superfamily
1FJ1E 3CCSE 2OY8A 5JVHE 4WF9E 1NJIG 5GAEG 1VQLE 4UY8G 5B3MO 1YI2E 1K73G 3J7ZG 4WCEE 3OW2E 1S72E 1K8AG 3CC4E 3IG9A 3CCRE 2OY1O 1RL6A 1YJWE 3PIPE 5AN9B 3CKGA 5DM7E 1KQSE 1VQ7E 1RJLC 3CMEE 3PIOE 2OY5O 5B10O 3CCLE 5MLCH 1P4PA 3CCEE 5B11O 4IO9E 1YJNE 1VQ6E 2QEXE 1W2BE 2OL8O 1VQNE 1N8RG 3G6EE 1VQ4E 2ZJQE 1YITE 3CXCE 3CCQE 1Q86G 1KC8G 3I56E 5DM6E 3G4SE 1JJ2E 1Q81G 4IOCE 5GAHG 4WFNE 3CD6E 2OTLE 2OYBO 2AF5A 2OL7A 5GADG 5GAGG 2PI3O 2ZJRE 5HL7E 1KD1G 3DLLE 2OTJE 3CC7E 1Q82G 4WFBE 4U67E 1M1KG 5B2AO 1M90G 1VQ8E 1QVFE 1Q7YG 2FKJA 1VQ9E 3IGEA 3CMAE 1VQME 3I55E 1VQ5E 4IOAE 3CC2E 3CCME 2HKDA 2G8CO 1VQOE 3CCVE 3CF5E 1OSPO 3CPWE 2I5ZO 5H1SI 1YHQE 2OL6O 5JVGE 2FKGA 2QA4E 1QVGE 3AUMO 1YJ9E 3CCUE 2CQLA 3CCJE 1VQPE 1YIJE 3EC5A 3G71E 2OY7A 2I5VO 1K9MG 2ZJPE 4WFAE 1VQKE 3CKFA
chains in the Genus database with same CATH topology
3CCSE 5JVHE 4WF9E 1NJIG 5GAEG 1VQLE 4UY8G 1YI2E 1K73G 3J7ZG 4WCEE 3OW2E 1S72E 1K8AG 3CC4E 3CCRE 1RL6A 1YJWE 3PIPE 5AN9B 1KQSE 5DM7E 1VQ7E 3CMEE 3PIOE 3CCLE 5MLCH 4IO9E 3CCEE 1YJNE 1VQ6E 2QEXE 1W2BE 1VQNE 1N8RG 3G6EE 1VQ4E 2ZJQE 1YITE 3CXCE 3CCQE 1Q86G 1KC8G 3I56E 5DM6E 3G4SE 1JJ2E 1Q81G 4IOCE 5GAHG 4WFNE 3CD6E 2OTLE 5GADG 5GAGG 2ZJRE 5HL7E 1KD1G 3DLLE 2OTJE 3CC7E 1Q82G 4WFBE 4U67E 1M1KG 1M90G 1VQ8E 1QVFE 1Q7YG 1VQ9E 3CMAE 1VQME 3I55E 1VQ5E 4IOAE 3CC2E 3CCME 1VQOE 3CCVE 3CF5E 3CPWE 5H1SI 1YHQE 5JVGE 2QA4E 1QVGE 1YJ9E 3CCUE 2CQLA 3CCJE 1VQPE 1YIJE 3G71E 1K9MG 2ZJPE 4WFAE 1VQKE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCS E;  5JVH E;  4WF9 E;  1NJI G;  5GAE G;  1VQL E;  4UY8 G;  1YI2 E;  1K73 G;  3J7Z G;  4WCE E;  3OW2 E;  1S72 E;  1K8A G;  3CC4 E;  3CCR E;  1RL6 A;  1YJW E;  3PIP E;  5AN9 B;  1KQS E;  5DM7 E;  1VQ7 E;  3CME E;  3PIO E;  3CCL E;  5MLC H;  4IO9 E;  3CCE E;  1YJN E;  1VQ6 E;  2QEX E;  1W2B E;  1VQN E;  1N8R G;  3G6E E;  1VQ4 E;  2ZJQ E;  1YIT E;  3CXC E;  3CCQ E;  1Q86 G;  1KC8 G;  3I56 E;  5DM6 E;  3G4S E;  1JJ2 E;  1Q81 G;  4IOC E;  5GAH G;  4WFN E;  3CD6 E;  2OTL E;  5GAD G;  5GAG G;  2ZJR E;  5HL7 E;  1KD1 G;  3DLL E;  2OTJ E;  3CC7 E;  1Q82 G;  4WFB E;  4U67 E;  1M1K G;  1M90 G;  1VQ8 E;  1QVF E;  1Q7Y G;  1VQ9 E;  3CMA E;  1VQM E;  3I55 E;  1VQ5 E;  4IOA E;  3CC2 E;  3CCM E;  1VQO E;  3CCV E;  3CF5 E;  3CPW E;  5H1S I;  1YHQ E;  5JVG E;  2QA4 E;  1QVG E;  1YJ9 E;  3CCU E;  2CQL A;  3CCJ E;  1VQP E;  1YIJ E;  3G71 E;  1K9M G;  2ZJP E;  4WFA E;  1VQK E; 
#chains in the Genus database with same CATH topology
 1FJ1 E;  3CCS E;  2OY8 A;  5JVH E;  4WF9 E;  1NJI G;  5GAE G;  1VQL E;  4UY8 G;  5B3M O;  1YI2 E;  1K73 G;  3J7Z G;  4WCE E;  3OW2 E;  1S72 E;  1K8A G;  3CC4 E;  3IG9 A;  3CCR E;  2OY1 O;  1RL6 A;  1YJW E;  3PIP E;  5AN9 B;  3CKG A;  5DM7 E;  1KQS E;  1VQ7 E;  1RJL C;  3CME E;  3PIO E;  2OY5 O;  5B10 O;  3CCL E;  5MLC H;  1P4P A;  3CCE E;  5B11 O;  4IO9 E;  1YJN E;  1VQ6 E;  2QEX E;  1W2B E;  2OL8 O;  1VQN E;  1N8R G;  3G6E E;  1VQ4 E;  2ZJQ E;  1YIT E;  3CXC E;  3CCQ E;  1Q86 G;  1KC8 G;  3I56 E;  5DM6 E;  3G4S E;  1JJ2 E;  1Q81 G;  4IOC E;  5GAH G;  4WFN E;  3CD6 E;  2OTL E;  2OYB O;  2AF5 A;  2OL7 A;  5GAD G;  5GAG G;  2PI3 O;  2ZJR E;  5HL7 E;  1KD1 G;  3DLL E;  2OTJ E;  3CC7 E;  1Q82 G;  4WFB E;  4U67 E;  1M1K G;  5B2A O;  1M90 G;  1VQ8 E;  1QVF E;  1Q7Y G;  2FKJ A;  1VQ9 E;  3IGE A;  3CMA E;  1VQM E;  3I55 E;  1VQ5 E;  4IOA E;  3CC2 E;  3CCM E;  2HKD A;  2G8C O;  1VQO E;  3CCV E;  3CF5 E;  1OSP O;  3CPW E;  2I5Z O;  5H1S I;  1YHQ E;  2OL6 O;  5JVG E;  2FKG A;  2QA4 E;  1QVG E;  3AUM O;  1YJ9 E;  3CCU E;  2CQL A;  3CCJ E;  1VQP E;  1YIJ E;  3EC5 A;  3G71 E;  2OY7 A;  2I5V O;  1K9M G;  2ZJP E;  4WFA E;  1VQK E;  3CKF A; 
#chains in the Genus database with same CATH homology
 3CCS E;  5JVH E;  4WF9 E;  1NJI G;  5GAE G;  1VQL E;  4UY8 G;  1YI2 E;  1K73 G;  3J7Z G;  4WCE E;  3OW2 E;  1S72 E;  1K8A G;  3CC4 E;  3CCR E;  1RL6 A;  1YJW E;  3PIP E;  5AN9 B;  1KQS E;  5DM7 E;  1VQ7 E;  3CME E;  3PIO E;  3CCL E;  5MLC H;  4IO9 E;  3CCE E;  1YJN E;  1VQ6 E;  2QEX E;  1W2B E;  1VQN E;  1N8R G;  3G6E E;  1VQ4 E;  2ZJQ E;  1YIT E;  3CXC E;  3CCQ E;  1Q86 G;  1KC8 G;  3I56 E;  5DM6 E;  3G4S E;  1JJ2 E;  1Q81 G;  4IOC E;  5GAH G;  4WFN E;  3CD6 E;  2OTL E;  5GAD G;  5GAG G;  2ZJR E;  5HL7 E;  1KD1 G;  3DLL E;  2OTJ E;  3CC7 E;  1Q82 G;  4WFB E;  4U67 E;  1M1K G;  1M90 G;  1VQ8 E;  1QVF E;  1Q7Y G;  1VQ9 E;  3CMA E;  1VQM E;  3I55 E;  1VQ5 E;  4IOA E;  3CC2 E;  3CCM E;  1VQO E;  3CCV E;  3CF5 E;  3CPW E;  5H1S I;  1YHQ E;  5JVG E;  2QA4 E;  1QVG E;  1YJ9 E;  3CCU E;  2CQL A;  3CCJ E;  1VQP E;  1YIJ E;  3G71 E;  1K9M G;  2ZJP E;  4WFA E;  1VQK E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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