3CCJE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccjE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccjE01
4WF9E 3CCEE 1YJNE 1NJIG 5GAHG 5AN9B 1Q81G 1N8RG 1QVGE 1K73G 5GADG 3G6EE 1VQME 1VQ7E 4UY8G 1RL6A 5HL7E 5GAEG 3I56E 1QVFE 3CC7E 1VQ5E 5GAGG 2CQLA 1VQ6E 4WFAE 3CCLE 4WFNE 3CCVE 3CXCE 1YJ9E 1M1KG 3G4SE 1YI2E 2QEXE 3CC2E 1M90G 3CCME 3G71E 1VQ8E 1KD1G 1YHQE 3PIPE 5H1SI 2ZJRE 3CD6E 3CMAE 1VQNE 3PIOE 1YIJE 4IOAE 3DLLE 3OW2E 1Q82G 1VQOE 4WCEE 1KC8G 1VQ9E 4IOCE 3CC4E 3CCQE 3CCUE 1VQLE 1VQKE 1JJ2E 2ZJPE 1VQ4E 1W2BE 3J7ZG 5DM6E 2OTLE 2QA4E 3CF5E 4IO9E 3CPWE 3CCRE 1YJWE 2OTJE 3CCJE 5JVGE 5JVHE 1Q7YG 1S72E 1Q86G 5MLCH 4WFBE 1VQPE 3I55E 1YITE 1KQSE 1K9MG 5DM7E 1K8AG 4U67E 3CCSE 2ZJQE 3CMEE
chains in the Genus database with same CATH superfamily
4WF9E 3CCEE 1YJNE 1NJIG 5GAHG 5AN9B 1Q81G 1N8RG 1QVGE 1K73G 5GADG 2I5ZO 3G6EE 1VQME 1VQ7E 3IGEA 4UY8G 1RL6A 5HL7E 5GAEG 3I56E 1QVFE 3CC7E 2OY7A 1VQ5E 2PI3O 5GAGG 2CQLA 1VQ6E 4WFAE 3CCLE 4WFNE 3CKFA 3CCVE 3CXCE 1YJ9E 1M1KG 3G4SE 1YI2E 3AUMO 1P4PA 2QEXE 3CC2E 1M90G 3CCME 3G71E 1VQ8E 1KD1G 1YHQE 3PIPE 5H1SI 5B11O 2ZJRE 3CD6E 3CMAE 1RJLC 2HKDA 1VQNE 2OY8A 3PIOE 5B3MO 1YIJE 1OSPO 4IOAE 3DLLE 5B2AO 1FJ1E 3OW2E 2G8CO 2I5VO 1Q82G 1VQOE 4WCEE 1KC8G 1VQ9E 4IOCE 2OL7A 3CC4E 3CCQE 3CCUE 1VQLE 1VQKE 1JJ2E 2ZJPE 1VQ4E 1W2BE 5B10O 3J7ZG 5DM6E 2OL6O 2OTLE 2QA4E 3CF5E 4IO9E 3EC5A 3CPWE 2FKGA 3CCRE 2OY1O 1YJWE 2OTJE 2OL8O 3CCJE 5JVGE 5JVHE 1Q7YG 1S72E 2OY5O 1Q86G 3CKGA 3IG9A 5MLCH 2OYBO 4WFBE 2FKJA 3I55E 1VQPE 1YITE 1KQSE 5DM7E 1K8AG 1K9MG 4U67E 3CCSE 2ZJQE 3CMEE 2AF5A
chains in the Genus database with same CATH topology
4WF9E 3CCEE 1YJNE 1NJIG 5GAHG 5AN9B 1Q81G 1N8RG 1QVGE 1K73G 5GADG 3G6EE 1VQME 1VQ7E 4UY8G 1RL6A 5HL7E 5GAEG 3I56E 1QVFE 3CC7E 1VQ5E 5GAGG 2CQLA 1VQ6E 4WFAE 3CCLE 4WFNE 3CCVE 3CXCE 1YJ9E 1M1KG 3G4SE 1YI2E 2QEXE 3CC2E 1M90G 3CCME 3G71E 1VQ8E 1KD1G 1YHQE 3PIPE 5H1SI 2ZJRE 3CD6E 3CMAE 1VQNE 3PIOE 1YIJE 4IOAE 3DLLE 3OW2E 1Q82G 1VQOE 4WCEE 1KC8G 1VQ9E 4IOCE 3CC4E 3CCQE 3CCUE 1VQLE 1VQKE 1JJ2E 2ZJPE 1VQ4E 1W2BE 3J7ZG 5DM6E 2OTLE 2QA4E 3CF5E 4IO9E 3CPWE 3CCRE 1YJWE 2OTJE 3CCJE 5JVGE 5JVHE 1Q7YG 1S72E 1Q86G 5MLCH 4WFBE 1VQPE 3I55E 1YITE 1KQSE 1K9MG 5DM7E 1K8AG 4U67E 3CCSE 2ZJQE 3CMEE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WF9 E;  3CCE E;  1YJN E;  1NJI G;  5GAH G;  5AN9 B;  1Q81 G;  1N8R G;  1QVG E;  1K73 G;  5GAD G;  3G6E E;  1VQM E;  1VQ7 E;  4UY8 G;  1RL6 A;  5HL7 E;  5GAE G;  3I56 E;  1QVF E;  3CC7 E;  1VQ5 E;  5GAG G;  2CQL A;  1VQ6 E;  4WFA E;  3CCL E;  4WFN E;  3CCV E;  3CXC E;  1YJ9 E;  1M1K G;  3G4S E;  1YI2 E;  2QEX E;  3CC2 E;  1M90 G;  3CCM E;  3G71 E;  1VQ8 E;  1KD1 G;  1YHQ E;  3PIP E;  5H1S I;  2ZJR E;  3CD6 E;  3CMA E;  1VQN E;  3PIO E;  1YIJ E;  4IOA E;  3DLL E;  3OW2 E;  1Q82 G;  1VQO E;  4WCE E;  1KC8 G;  1VQ9 E;  4IOC E;  3CC4 E;  3CCQ E;  3CCU E;  1VQL E;  1VQK E;  1JJ2 E;  2ZJP E;  1VQ4 E;  1W2B E;  3J7Z G;  5DM6 E;  2OTL E;  2QA4 E;  3CF5 E;  4IO9 E;  3CPW E;  3CCR E;  1YJW E;  2OTJ E;  3CCJ E;  5JVG E;  5JVH E;  1Q7Y G;  1S72 E;  1Q86 G;  5MLC H;  4WFB E;  1VQP E;  3I55 E;  1YIT E;  1KQS E;  1K9M G;  5DM7 E;  1K8A G;  4U67 E;  3CCS E;  2ZJQ E;  3CME E; 
#chains in the Genus database with same CATH topology
 4WF9 E;  3CCE E;  1YJN E;  1NJI G;  5GAH G;  5AN9 B;  1Q81 G;  1N8R G;  1QVG E;  1K73 G;  5GAD G;  2I5Z O;  3G6E E;  1VQM E;  1VQ7 E;  3IGE A;  4UY8 G;  1RL6 A;  5HL7 E;  5GAE G;  3I56 E;  1QVF E;  3CC7 E;  2OY7 A;  1VQ5 E;  2PI3 O;  5GAG G;  2CQL A;  1VQ6 E;  4WFA E;  3CCL E;  4WFN E;  3CKF A;  3CCV E;  3CXC E;  1YJ9 E;  1M1K G;  3G4S E;  1YI2 E;  3AUM O;  1P4P A;  2QEX E;  3CC2 E;  1M90 G;  3CCM E;  3G71 E;  1VQ8 E;  1KD1 G;  1YHQ E;  3PIP E;  5H1S I;  5B11 O;  2ZJR E;  3CD6 E;  3CMA E;  1RJL C;  2HKD A;  1VQN E;  2OY8 A;  3PIO E;  5B3M O;  1YIJ E;  1OSP O;  4IOA E;  3DLL E;  5B2A O;  1FJ1 E;  3OW2 E;  2G8C O;  2I5V O;  1Q82 G;  1VQO E;  4WCE E;  1KC8 G;  1VQ9 E;  4IOC E;  2OL7 A;  3CC4 E;  3CCQ E;  3CCU E;  1VQL E;  1VQK E;  1JJ2 E;  2ZJP E;  1VQ4 E;  1W2B E;  5B10 O;  3J7Z G;  5DM6 E;  2OL6 O;  2OTL E;  2QA4 E;  3CF5 E;  4IO9 E;  3EC5 A;  3CPW E;  2FKG A;  3CCR E;  2OY1 O;  1YJW E;  2OTJ E;  2OL8 O;  3CCJ E;  5JVG E;  5JVH E;  1Q7Y G;  1S72 E;  2OY5 O;  1Q86 G;  3CKG A;  3IG9 A;  5MLC H;  2OYB O;  4WFB E;  2FKJ A;  3I55 E;  1VQP E;  1YIT E;  1KQS E;  5DM7 E;  1K8A G;  1K9M G;  4U67 E;  3CCS E;  2ZJQ E;  3CME E;  2AF5 A; 
#chains in the Genus database with same CATH homology
 4WF9 E;  3CCE E;  1YJN E;  1NJI G;  5GAH G;  5AN9 B;  1Q81 G;  1N8R G;  1QVG E;  1K73 G;  5GAD G;  3G6E E;  1VQM E;  1VQ7 E;  4UY8 G;  1RL6 A;  5HL7 E;  5GAE G;  3I56 E;  1QVF E;  3CC7 E;  1VQ5 E;  5GAG G;  2CQL A;  1VQ6 E;  4WFA E;  3CCL E;  4WFN E;  3CCV E;  3CXC E;  1YJ9 E;  1M1K G;  3G4S E;  1YI2 E;  2QEX E;  3CC2 E;  1M90 G;  3CCM E;  3G71 E;  1VQ8 E;  1KD1 G;  1YHQ E;  3PIP E;  5H1S I;  2ZJR E;  3CD6 E;  3CMA E;  1VQN E;  3PIO E;  1YIJ E;  4IOA E;  3DLL E;  3OW2 E;  1Q82 G;  1VQO E;  4WCE E;  1KC8 G;  1VQ9 E;  4IOC E;  3CC4 E;  3CCQ E;  3CCU E;  1VQL E;  1VQK E;  1JJ2 E;  2ZJP E;  1VQ4 E;  1W2B E;  3J7Z G;  5DM6 E;  2OTL E;  2QA4 E;  3CF5 E;  4IO9 E;  3CPW E;  3CCR E;  1YJW E;  2OTJ E;  3CCJ E;  5JVG E;  5JVH E;  1Q7Y G;  1S72 E;  1Q86 G;  5MLC H;  4WFB E;  1VQP E;  3I55 E;  1YIT E;  1KQS E;  1K9M G;  5DM7 E;  1K8A G;  4U67 E;  3CCS E;  2ZJQ E;  3CME E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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