3CCLE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cclE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cclE01
1Q82G 4UY8G 3G71E 1KC8G 3G6EE 1VQOE 3CCRE 1M90G 2QA4E 3PIPE 1VQ9E 5AN9B 3CCSE 1K9MG 3CC4E 3CC2E 4U67E 1VQLE 1VQPE 1YI2E 1YJ9E 2ZJPE 1QVFE 1YIJE 3CCUE 5GADG 2OTJE 3CC7E 1Q7YG 4IOCE 3I56E 2ZJQE 3CXCE 1YHQE 4WFNE 3OW2E 1VQME 1VQ7E 4WFAE 3CF5E 3CPWE 1KQSE 2ZJRE 5GAGG 4IO9E 1VQNE 4WF9E 5DM7E 5MLCH 5GAEG 1VQ6E 1YITE 5H1SI 3PIOE 1VQ4E 2OTLE 1N8RG 3CCQE 5GAHG 3CMEE 1NJIG 3CD6E 5HL7E 3I55E 3CCJE 3G4SE 1JJ2E 1KD1G 4WCEE 3CCME 2QEXE 5JVHE 4IOAE 1K8AG 5JVGE 3CCVE 3CCEE 1Q81G 3J7ZG 3CCLE 3CMAE 1VQ5E 1S72E 5DM6E 4WFBE 1W2BE 1QVGE 1VQKE 1Q86G 3DLLE 1M1KG 1RL6A 2CQLA 1VQ8E 1YJWE 1YJNE 1K73G
chains in the Genus database with same CATH superfamily
1Q82G 4UY8G 2OL6O 2OYBO 3G71E 1KC8G 3G6EE 1VQOE 3CCRE 1OSPO 1M90G 2QA4E 3PIPE 2HKDA 1VQ9E 5AN9B 3CCSE 1K9MG 3CC4E 3CC2E 2I5ZO 3CKGA 4U67E 1VQLE 1VQPE 5B3MO 5B11O 1YI2E 1YJ9E 2ZJPE 1QVFE 1YIJE 3CCUE 5GADG 2OTJE 2I5VO 3CC7E 5B10O 3IGEA 1Q7YG 4IOCE 3I56E 2ZJQE 3CXCE 1YHQE 3AUMO 2OY5O 4WFNE 3OW2E 1VQME 1VQ7E 4WFAE 3CF5E 3CPWE 3EC5A 2ZJRE 1KQSE 5GAGG 4IO9E 1VQNE 2OL7A 4WF9E 5DM7E 5MLCH 5GAEG 1VQ6E 1YITE 2PI3O 2FKJA 1FJ1E 5H1SI 2OY8A 3PIOE 1VQ4E 2OTLE 1N8RG 3CCQE 5GAHG 3CMEE 1NJIG 3CD6E 2FKGA 5HL7E 3I55E 3CCJE 3G4SE 1JJ2E 1KD1G 4WCEE 2G8CO 3CCME 2QEXE 5B2AO 5JVHE 4IOAE 1K8AG 1RJLC 5JVGE 3CCVE 3CCEE 1Q81G 3J7ZG 3CCLE 2OY7A 3CMAE 1VQ5E 2OL8O 2OY1O 2AF5A 3IG9A 1S72E 5DM6E 4WFBE 1W2BE 1QVGE 1VQKE 1Q86G 3DLLE 1M1KG 1RL6A 2CQLA 1VQ8E 1P4PA 3CKFA 1YJWE 1YJNE 1K73G
chains in the Genus database with same CATH topology
1Q82G 4UY8G 3G71E 1KC8G 3G6EE 1VQOE 3CCRE 1M90G 2QA4E 3PIPE 1VQ9E 5AN9B 3CCSE 1K9MG 3CC4E 3CC2E 4U67E 1VQLE 1VQPE 1YI2E 1YJ9E 2ZJPE 1QVFE 1YIJE 3CCUE 5GADG 2OTJE 3CC7E 1Q7YG 4IOCE 3I56E 2ZJQE 3CXCE 1YHQE 4WFNE 3OW2E 1VQME 1VQ7E 4WFAE 3CF5E 3CPWE 1KQSE 2ZJRE 5GAGG 4IO9E 1VQNE 4WF9E 5DM7E 5MLCH 5GAEG 1VQ6E 1YITE 5H1SI 3PIOE 1VQ4E 2OTLE 1N8RG 3CCQE 5GAHG 3CMEE 1NJIG 3CD6E 5HL7E 3I55E 3CCJE 3G4SE 1JJ2E 1KD1G 4WCEE 3CCME 2QEXE 5JVHE 4IOAE 1K8AG 5JVGE 3CCVE 3CCEE 1Q81G 3J7ZG 3CCLE 3CMAE 1VQ5E 1S72E 5DM6E 4WFBE 1W2BE 1QVGE 1VQKE 1Q86G 3DLLE 1M1KG 1RL6A 2CQLA 1VQ8E 1YJWE 1YJNE 1K73G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q82 G;  4UY8 G;  3G71 E;  1KC8 G;  3G6E E;  1VQO E;  3CCR E;  1M90 G;  2QA4 E;  3PIP E;  1VQ9 E;  5AN9 B;  3CCS E;  1K9M G;  3CC4 E;  3CC2 E;  4U67 E;  1VQL E;  1VQP E;  1YI2 E;  1YJ9 E;  2ZJP E;  1QVF E;  1YIJ E;  3CCU E;  5GAD G;  2OTJ E;  3CC7 E;  1Q7Y G;  4IOC E;  3I56 E;  2ZJQ E;  3CXC E;  1YHQ E;  4WFN E;  3OW2 E;  1VQM E;  1VQ7 E;  4WFA E;  3CF5 E;  3CPW E;  1KQS E;  2ZJR E;  5GAG G;  4IO9 E;  1VQN E;  4WF9 E;  5DM7 E;  5MLC H;  5GAE G;  1VQ6 E;  1YIT E;  5H1S I;  3PIO E;  1VQ4 E;  2OTL E;  1N8R G;  3CCQ E;  5GAH G;  3CME E;  1NJI G;  3CD6 E;  5HL7 E;  3I55 E;  3CCJ E;  3G4S E;  1JJ2 E;  1KD1 G;  4WCE E;  3CCM E;  2QEX E;  5JVH E;  4IOA E;  1K8A G;  5JVG E;  3CCV E;  3CCE E;  1Q81 G;  3J7Z G;  3CCL E;  3CMA E;  1VQ5 E;  1S72 E;  5DM6 E;  4WFB E;  1W2B E;  1QVG E;  1VQK E;  1Q86 G;  3DLL E;  1M1K G;  1RL6 A;  2CQL A;  1VQ8 E;  1YJW E;  1YJN E;  1K73 G; 
#chains in the Genus database with same CATH topology
 1Q82 G;  4UY8 G;  2OL6 O;  2OYB O;  3G71 E;  1KC8 G;  3G6E E;  1VQO E;  3CCR E;  1OSP O;  1M90 G;  2QA4 E;  3PIP E;  2HKD A;  1VQ9 E;  5AN9 B;  3CCS E;  1K9M G;  3CC4 E;  3CC2 E;  2I5Z O;  3CKG A;  4U67 E;  1VQL E;  1VQP E;  5B3M O;  5B11 O;  1YI2 E;  1YJ9 E;  2ZJP E;  1QVF E;  1YIJ E;  3CCU E;  5GAD G;  2OTJ E;  2I5V O;  3CC7 E;  5B10 O;  3IGE A;  1Q7Y G;  4IOC E;  3I56 E;  2ZJQ E;  3CXC E;  1YHQ E;  3AUM O;  2OY5 O;  4WFN E;  3OW2 E;  1VQM E;  1VQ7 E;  4WFA E;  3CF5 E;  3CPW E;  3EC5 A;  2ZJR E;  1KQS E;  5GAG G;  4IO9 E;  1VQN E;  2OL7 A;  4WF9 E;  5DM7 E;  5MLC H;  5GAE G;  1VQ6 E;  1YIT E;  2PI3 O;  2FKJ A;  1FJ1 E;  5H1S I;  2OY8 A;  3PIO E;  1VQ4 E;  2OTL E;  1N8R G;  3CCQ E;  5GAH G;  3CME E;  1NJI G;  3CD6 E;  2FKG A;  5HL7 E;  3I55 E;  3CCJ E;  3G4S E;  1JJ2 E;  1KD1 G;  4WCE E;  2G8C O;  3CCM E;  2QEX E;  5B2A O;  5JVH E;  4IOA E;  1K8A G;  1RJL C;  5JVG E;  3CCV E;  3CCE E;  1Q81 G;  3J7Z G;  3CCL E;  2OY7 A;  3CMA E;  1VQ5 E;  2OL8 O;  2OY1 O;  2AF5 A;  3IG9 A;  1S72 E;  5DM6 E;  4WFB E;  1W2B E;  1QVG E;  1VQK E;  1Q86 G;  3DLL E;  1M1K G;  1RL6 A;  2CQL A;  1VQ8 E;  1P4P A;  3CKF A;  1YJW E;  1YJN E;  1K73 G; 
#chains in the Genus database with same CATH homology
 1Q82 G;  4UY8 G;  3G71 E;  1KC8 G;  3G6E E;  1VQO E;  3CCR E;  1M90 G;  2QA4 E;  3PIP E;  1VQ9 E;  5AN9 B;  3CCS E;  1K9M G;  3CC4 E;  3CC2 E;  4U67 E;  1VQL E;  1VQP E;  1YI2 E;  1YJ9 E;  2ZJP E;  1QVF E;  1YIJ E;  3CCU E;  5GAD G;  2OTJ E;  3CC7 E;  1Q7Y G;  4IOC E;  3I56 E;  2ZJQ E;  3CXC E;  1YHQ E;  4WFN E;  3OW2 E;  1VQM E;  1VQ7 E;  4WFA E;  3CF5 E;  3CPW E;  1KQS E;  2ZJR E;  5GAG G;  4IO9 E;  1VQN E;  4WF9 E;  5DM7 E;  5MLC H;  5GAE G;  1VQ6 E;  1YIT E;  5H1S I;  3PIO E;  1VQ4 E;  2OTL E;  1N8R G;  3CCQ E;  5GAH G;  3CME E;  1NJI G;  3CD6 E;  5HL7 E;  3I55 E;  3CCJ E;  3G4S E;  1JJ2 E;  1KD1 G;  4WCE E;  3CCM E;  2QEX E;  5JVH E;  4IOA E;  1K8A G;  5JVG E;  3CCV E;  3CCE E;  1Q81 G;  3J7Z G;  3CCL E;  3CMA E;  1VQ5 E;  1S72 E;  5DM6 E;  4WFB E;  1W2B E;  1QVG E;  1VQK E;  1Q86 G;  3DLL E;  1M1K G;  1RL6 A;  2CQL A;  1VQ8 E;  1YJW E;  1YJN E;  1K73 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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