3CCME

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2611u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccmE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccmE01
1KQSE 3CCJE 5DM7E 4U67E 5MLCH 4IOAE 1S72E 4WFAE 3CC7E 3CMAE 3G71E 3I55E 4WF9E 4UY8G 3J7ZG 1NJIG 3CCVE 1YJWE 1QVFE 1YJ9E 4IOCE 3PIPE 3CPWE 3CCUE 1K73G 4WCEE 1QVGE 5GAGG 3CCLE 3CCME 1VQLE 1Q7YG 1KD1G 1Q82G 1VQ8E 2OTLE 1KC8G 1VQNE 4WFBE 1VQPE 5H1SI 5GAHG 2CQLA 5GAEG 5HL7E 1N8RG 2QEXE 1M90G 1VQ6E 3PIOE 3DLLE 3CD6E 1JJ2E 3CCEE 1YITE 3I56E 3G4SE 1VQ4E 1VQME 1M1KG 2OTJE 5GADG 2ZJQE 3CCRE 1YHQE 1VQ7E 1VQKE 1YIJE 3G6EE 3OW2E 1RL6A 2QA4E 1Q86G 1K8AG 4IO9E 4WFNE 5AN9B 2ZJPE 3CCQE 3CC4E 3CCSE 1YJNE 1VQ5E 5DM6E 3CF5E 1W2BE 3CXCE 5JVGE 1VQOE 1YI2E 5JVHE 3CMEE 1K9MG 1VQ9E 3CC2E 2ZJRE 1Q81G
chains in the Genus database with same CATH superfamily
1KQSE 3CCJE 2HKDA 5DM7E 1RJLC 3EC5A 2FKGA 2OY5O 2AF5A 4U67E 5MLCH 4IOAE 1S72E 4WFAE 3CC7E 1P4PA 3CMAE 3G71E 3I55E 4WF9E 4UY8G 3J7ZG 1NJIG 3CCVE 1YJWE 1QVFE 1Q81G 1YJ9E 4IOCE 3PIPE 3CPWE 3CCUE 2OY1O 1K73G 4WCEE 2PI3O 1QVGE 5GAGG 3CCLE 3CCME 1VQLE 1Q7YG 1KD1G 1Q82G 1VQ8E 2OTLE 1KC8G 1VQNE 1OSPO 4WFBE 1VQPE 5H1SI 5GAHG 2CQLA 5GAEG 5B11O 5B3MO 5HL7E 1N8RG 2QEXE 1M90G 1VQ6E 2OL8O 3PIOE 5B2AO 3DLLE 3CD6E 1JJ2E 3CCEE 1YITE 3CKGA 3I56E 3G4SE 1VQ4E 2OYBO 3CKFA 1VQME 1M1KG 5GADG 2OTJE 2ZJQE 3CCRE 1YHQE 1VQ7E 1VQKE 3IG9A 1YIJE 1FJ1E 3G6EE 3OW2E 1RL6A 2OL7A 2QA4E 1Q86G 1K8AG 4IO9E 2I5ZO 4WFNE 2FKJA 5AN9B 3IGEA 2ZJPE 3CCQE 3CC4E 3AUMO 3CCSE 1YJNE 2I5VO 1VQ5E 5DM6E 3CF5E 2OY8A 1W2BE 3CXCE 5JVGE 1VQOE 2OL6O 1YI2E 5JVHE 2OY7A 3CMEE 2G8CO 1K9MG 1VQ9E 3CC2E 2ZJRE 5B10O
chains in the Genus database with same CATH topology
1KQSE 3CCJE 5DM7E 4U67E 5MLCH 4IOAE 1S72E 4WFAE 3CC7E 3CMAE 3G71E 3I55E 4WF9E 4UY8G 3J7ZG 1NJIG 3CCVE 1YJWE 1QVFE 1YJ9E 4IOCE 3PIPE 3CPWE 3CCUE 1K73G 4WCEE 1QVGE 5GAGG 3CCLE 3CCME 1VQLE 1Q7YG 1KD1G 1Q82G 1VQ8E 2OTLE 1KC8G 1VQNE 4WFBE 1VQPE 5H1SI 5GAHG 2CQLA 5GAEG 5HL7E 1N8RG 2QEXE 1M90G 1VQ6E 3PIOE 3DLLE 3CD6E 1JJ2E 3CCEE 1YITE 3I56E 3G4SE 1VQ4E 1VQME 1M1KG 2OTJE 5GADG 2ZJQE 3CCRE 1YHQE 1VQ7E 1VQKE 1YIJE 3G6EE 3OW2E 1RL6A 2QA4E 1Q86G 1K8AG 4IO9E 4WFNE 5AN9B 2ZJPE 3CCQE 3CC4E 3CCSE 1YJNE 1VQ5E 5DM6E 3CF5E 1W2BE 3CXCE 5JVGE 1VQOE 1YI2E 5JVHE 3CMEE 1K9MG 1VQ9E 3CC2E 2ZJRE 1Q81G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KQS E;  3CCJ E;  5DM7 E;  4U67 E;  5MLC H;  4IOA E;  1S72 E;  4WFA E;  3CC7 E;  3CMA E;  3G71 E;  3I55 E;  4WF9 E;  4UY8 G;  3J7Z G;  1NJI G;  3CCV E;  1YJW E;  1QVF E;  1YJ9 E;  4IOC E;  3PIP E;  3CPW E;  3CCU E;  1K73 G;  4WCE E;  1QVG E;  5GAG G;  3CCL E;  3CCM E;  1VQL E;  1Q7Y G;  1KD1 G;  1Q82 G;  1VQ8 E;  2OTL E;  1KC8 G;  1VQN E;  4WFB E;  1VQP E;  5H1S I;  5GAH G;  2CQL A;  5GAE G;  5HL7 E;  1N8R G;  2QEX E;  1M90 G;  1VQ6 E;  3PIO E;  3DLL E;  3CD6 E;  1JJ2 E;  3CCE E;  1YIT E;  3I56 E;  3G4S E;  1VQ4 E;  1VQM E;  1M1K G;  2OTJ E;  5GAD G;  2ZJQ E;  3CCR E;  1YHQ E;  1VQ7 E;  1VQK E;  1YIJ E;  3G6E E;  3OW2 E;  1RL6 A;  2QA4 E;  1Q86 G;  1K8A G;  4IO9 E;  4WFN E;  5AN9 B;  2ZJP E;  3CCQ E;  3CC4 E;  3CCS E;  1YJN E;  1VQ5 E;  5DM6 E;  3CF5 E;  1W2B E;  3CXC E;  5JVG E;  1VQO E;  1YI2 E;  5JVH E;  3CME E;  1K9M G;  1VQ9 E;  3CC2 E;  2ZJR E;  1Q81 G; 
#chains in the Genus database with same CATH topology
 1KQS E;  3CCJ E;  2HKD A;  5DM7 E;  1RJL C;  3EC5 A;  2FKG A;  2OY5 O;  2AF5 A;  4U67 E;  5MLC H;  4IOA E;  1S72 E;  4WFA E;  3CC7 E;  1P4P A;  3CMA E;  3G71 E;  3I55 E;  4WF9 E;  4UY8 G;  3J7Z G;  1NJI G;  3CCV E;  1YJW E;  1QVF E;  1Q81 G;  1YJ9 E;  4IOC E;  3PIP E;  3CPW E;  3CCU E;  2OY1 O;  1K73 G;  4WCE E;  2PI3 O;  1QVG E;  5GAG G;  3CCL E;  3CCM E;  1VQL E;  1Q7Y G;  1KD1 G;  1Q82 G;  1VQ8 E;  2OTL E;  1KC8 G;  1VQN E;  1OSP O;  4WFB E;  1VQP E;  5H1S I;  5GAH G;  2CQL A;  5GAE G;  5B11 O;  5B3M O;  5HL7 E;  1N8R G;  2QEX E;  1M90 G;  1VQ6 E;  2OL8 O;  3PIO E;  5B2A O;  3DLL E;  3CD6 E;  1JJ2 E;  3CCE E;  1YIT E;  3CKG A;  3I56 E;  3G4S E;  1VQ4 E;  2OYB O;  3CKF A;  1VQM E;  1M1K G;  5GAD G;  2OTJ E;  2ZJQ E;  3CCR E;  1YHQ E;  1VQ7 E;  1VQK E;  3IG9 A;  1YIJ E;  1FJ1 E;  3G6E E;  3OW2 E;  1RL6 A;  2OL7 A;  2QA4 E;  1Q86 G;  1K8A G;  4IO9 E;  2I5Z O;  4WFN E;  2FKJ A;  5AN9 B;  3IGE A;  2ZJP E;  3CCQ E;  3CC4 E;  3AUM O;  3CCS E;  1YJN E;  2I5V O;  1VQ5 E;  5DM6 E;  3CF5 E;  2OY8 A;  1W2B E;  3CXC E;  5JVG E;  1VQO E;  2OL6 O;  1YI2 E;  5JVH E;  2OY7 A;  3CME E;  2G8C O;  1K9M G;  1VQ9 E;  3CC2 E;  2ZJR E;  5B10 O; 
#chains in the Genus database with same CATH homology
 1KQS E;  3CCJ E;  5DM7 E;  4U67 E;  5MLC H;  4IOA E;  1S72 E;  4WFA E;  3CC7 E;  3CMA E;  3G71 E;  3I55 E;  4WF9 E;  4UY8 G;  3J7Z G;  1NJI G;  3CCV E;  1YJW E;  1QVF E;  1YJ9 E;  4IOC E;  3PIP E;  3CPW E;  3CCU E;  1K73 G;  4WCE E;  1QVG E;  5GAG G;  3CCL E;  3CCM E;  1VQL E;  1Q7Y G;  1KD1 G;  1Q82 G;  1VQ8 E;  2OTL E;  1KC8 G;  1VQN E;  4WFB E;  1VQP E;  5H1S I;  5GAH G;  2CQL A;  5GAE G;  5HL7 E;  1N8R G;  2QEX E;  1M90 G;  1VQ6 E;  3PIO E;  3DLL E;  3CD6 E;  1JJ2 E;  3CCE E;  1YIT E;  3I56 E;  3G4S E;  1VQ4 E;  1VQM E;  1M1K G;  2OTJ E;  5GAD G;  2ZJQ E;  3CCR E;  1YHQ E;  1VQ7 E;  1VQK E;  1YIJ E;  3G6E E;  3OW2 E;  1RL6 A;  2QA4 E;  1Q86 G;  1K8A G;  4IO9 E;  4WFN E;  5AN9 B;  2ZJP E;  3CCQ E;  3CC4 E;  3CCS E;  1YJN E;  1VQ5 E;  5DM6 E;  3CF5 E;  1W2B E;  3CXC E;  5JVG E;  1VQO E;  1YI2 E;  5JVH E;  3CME E;  1K9M G;  1VQ9 E;  3CC2 E;  2ZJR E;  1Q81 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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