3CCQE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccqE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccqE01
3CC4E 3CCLE 3CXCE 1YITE 1Q86G 1YHQE 1M90G 3I56E 2ZJRE 3CC7E 1YIJE 2ZJQE 1VQOE 1YI2E 5DM6E 5AN9B 5H1SI 1K73G 3CCUE 3DLLE 1VQ4E 5GAHG 1NJIG 1VQ9E 4IOCE 2ZJPE 1K9MG 1QVGE 3G6EE 2OTJE 4IOAE 1VQ5E 4U67E 5JVGE 1KC8G 1K8AG 5DM7E 2CQLA 1YJWE 2QA4E 1VQ8E 1RL6A 1Q7YG 4IO9E 3CMAE 4WFAE 1JJ2E 3CCME 4WFBE 3CF5E 3PIPE 3CCQE 5JVHE 3CCRE 1YJNE 1W2BE 2OTLE 1VQNE 5HL7E 3CPWE 1Q81G 1M1KG 1KD1G 3CCVE 3CMEE 1VQKE 1VQLE 1KQSE 3J7ZG 3I55E 1VQ7E 1Q82G 3CCJE 5GAEG 4WFNE 1N8RG 2QEXE 1VQ6E 3CCSE 4UY8G 3G71E 3OW2E 1VQPE 3CD6E 5MLCH 5GAGG 5GADG 1VQME 1S72E 1QVFE 3CC2E 1YJ9E 4WCEE 3G4SE 3PIOE 3CCEE 4WF9E
chains in the Genus database with same CATH superfamily
2OL7A 3CC4E 3CCLE 1RJLC 3CXCE 1YITE 2OY8A 1Q86G 5B2AO 1YHQE 1M90G 3I56E 2OL8O 2ZJRE 3CC7E 1YIJE 2FKGA 2ZJQE 1VQOE 1YI2E 5DM6E 5AN9B 5H1SI 1K73G 3CCUE 3DLLE 1VQ4E 5GAHG 1NJIG 1VQ9E 4IOCE 5B10O 2ZJPE 1K9MG 1QVGE 3G6EE 2OTJE 4IOAE 1VQ5E 4U67E 5JVGE 1KC8G 1K8AG 1P4PA 5DM7E 2PI3O 2CQLA 1YJWE 3CKFA 2QA4E 1VQ8E 1RL6A 1Q7YG 4IO9E 2OL6O 2HKDA 5B11O 3CMAE 2OY5O 4WFAE 3EC5A 2G8CO 5B3MO 1JJ2E 3CCME 4WFBE 3CF5E 3PIPE 2OY7A 3CCQE 3IGEA 5JVHE 3CCRE 2OY1O 1YJNE 1W2BE 2OTLE 2AF5A 1VQNE 5HL7E 3AUMO 3CPWE 1OSPO 1Q81G 1M1KG 1KD1G 2I5ZO 2FKJA 3CCVE 3CMEE 1VQKE 1VQLE 1KQSE 3CKGA 3J7ZG 3I55E 1VQ7E 1Q82G 3CCJE 5GAEG 4WFNE 1N8RG 3IG9A 2QEXE 1VQ6E 3CCSE 4UY8G 3G71E 1FJ1E 3OW2E 1VQPE 3CD6E 5MLCH 5GAGG 5GADG 2I5VO 1VQME 1S72E 1QVFE 3CC2E 1YJ9E 4WCEE 3G4SE 3PIOE 2OYBO 3CCEE 4WF9E
chains in the Genus database with same CATH topology
3CC4E 3CCLE 3CXCE 1YITE 1Q86G 1YHQE 1M90G 3I56E 2ZJRE 3CC7E 1YIJE 2ZJQE 1VQOE 1YI2E 5DM6E 5AN9B 5H1SI 1K73G 3CCUE 3DLLE 1VQ4E 5GAHG 1NJIG 1VQ9E 4IOCE 2ZJPE 1K9MG 1QVGE 3G6EE 2OTJE 4IOAE 1VQ5E 4U67E 5JVGE 1KC8G 1K8AG 5DM7E 2CQLA 1YJWE 2QA4E 1VQ8E 1RL6A 1Q7YG 4IO9E 3CMAE 4WFAE 1JJ2E 3CCME 4WFBE 3CF5E 3PIPE 3CCQE 5JVHE 3CCRE 1YJNE 1W2BE 2OTLE 1VQNE 5HL7E 3CPWE 1Q81G 1M1KG 1KD1G 3CCVE 3CMEE 1VQKE 1VQLE 1KQSE 3J7ZG 3I55E 1VQ7E 1Q82G 3CCJE 5GAEG 4WFNE 1N8RG 2QEXE 1VQ6E 3CCSE 4UY8G 3G71E 3OW2E 1VQPE 3CD6E 5MLCH 5GAGG 5GADG 1VQME 1S72E 1QVFE 3CC2E 1YJ9E 4WCEE 3G4SE 3PIOE 3CCEE 4WF9E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CC4 E;  3CCL E;  3CXC E;  1YIT E;  1Q86 G;  1YHQ E;  1M90 G;  3I56 E;  2ZJR E;  3CC7 E;  1YIJ E;  2ZJQ E;  1VQO E;  1YI2 E;  5DM6 E;  5AN9 B;  5H1S I;  1K73 G;  3CCU E;  3DLL E;  1VQ4 E;  5GAH G;  1NJI G;  1VQ9 E;  4IOC E;  2ZJP E;  1K9M G;  1QVG E;  3G6E E;  2OTJ E;  4IOA E;  1VQ5 E;  4U67 E;  5JVG E;  1KC8 G;  1K8A G;  5DM7 E;  2CQL A;  1YJW E;  2QA4 E;  1VQ8 E;  1RL6 A;  1Q7Y G;  4IO9 E;  3CMA E;  4WFA E;  1JJ2 E;  3CCM E;  4WFB E;  3CF5 E;  3PIP E;  3CCQ E;  5JVH E;  3CCR E;  1YJN E;  1W2B E;  2OTL E;  1VQN E;  5HL7 E;  3CPW E;  1Q81 G;  1M1K G;  1KD1 G;  3CCV E;  3CME E;  1VQK E;  1VQL E;  1KQS E;  3J7Z G;  3I55 E;  1VQ7 E;  1Q82 G;  3CCJ E;  5GAE G;  4WFN E;  1N8R G;  2QEX E;  1VQ6 E;  3CCS E;  4UY8 G;  3G71 E;  3OW2 E;  1VQP E;  3CD6 E;  5MLC H;  5GAG G;  5GAD G;  1VQM E;  1S72 E;  1QVF E;  3CC2 E;  1YJ9 E;  4WCE E;  3G4S E;  3PIO E;  3CCE E;  4WF9 E; 
#chains in the Genus database with same CATH topology
 2OL7 A;  3CC4 E;  3CCL E;  1RJL C;  3CXC E;  1YIT E;  2OY8 A;  1Q86 G;  5B2A O;  1YHQ E;  1M90 G;  3I56 E;  2OL8 O;  2ZJR E;  3CC7 E;  1YIJ E;  2FKG A;  2ZJQ E;  1VQO E;  1YI2 E;  5DM6 E;  5AN9 B;  5H1S I;  1K73 G;  3CCU E;  3DLL E;  1VQ4 E;  5GAH G;  1NJI G;  1VQ9 E;  4IOC E;  5B10 O;  2ZJP E;  1K9M G;  1QVG E;  3G6E E;  2OTJ E;  4IOA E;  1VQ5 E;  4U67 E;  5JVG E;  1KC8 G;  1K8A G;  1P4P A;  5DM7 E;  2PI3 O;  2CQL A;  1YJW E;  3CKF A;  2QA4 E;  1VQ8 E;  1RL6 A;  1Q7Y G;  4IO9 E;  2OL6 O;  2HKD A;  5B11 O;  3CMA E;  2OY5 O;  4WFA E;  3EC5 A;  2G8C O;  5B3M O;  1JJ2 E;  3CCM E;  4WFB E;  3CF5 E;  3PIP E;  2OY7 A;  3CCQ E;  3IGE A;  5JVH E;  3CCR E;  2OY1 O;  1YJN E;  1W2B E;  2OTL E;  2AF5 A;  1VQN E;  5HL7 E;  3AUM O;  3CPW E;  1OSP O;  1Q81 G;  1M1K G;  1KD1 G;  2I5Z O;  2FKJ A;  3CCV E;  3CME E;  1VQK E;  1VQL E;  1KQS E;  3CKG A;  3J7Z G;  3I55 E;  1VQ7 E;  1Q82 G;  3CCJ E;  5GAE G;  4WFN E;  1N8R G;  3IG9 A;  2QEX E;  1VQ6 E;  3CCS E;  4UY8 G;  3G71 E;  1FJ1 E;  3OW2 E;  1VQP E;  3CD6 E;  5MLC H;  5GAG G;  5GAD G;  2I5V O;  1VQM E;  1S72 E;  1QVF E;  3CC2 E;  1YJ9 E;  4WCE E;  3G4S E;  3PIO E;  2OYB O;  3CCE E;  4WF9 E; 
#chains in the Genus database with same CATH homology
 3CC4 E;  3CCL E;  3CXC E;  1YIT E;  1Q86 G;  1YHQ E;  1M90 G;  3I56 E;  2ZJR E;  3CC7 E;  1YIJ E;  2ZJQ E;  1VQO E;  1YI2 E;  5DM6 E;  5AN9 B;  5H1S I;  1K73 G;  3CCU E;  3DLL E;  1VQ4 E;  5GAH G;  1NJI G;  1VQ9 E;  4IOC E;  2ZJP E;  1K9M G;  1QVG E;  3G6E E;  2OTJ E;  4IOA E;  1VQ5 E;  4U67 E;  5JVG E;  1KC8 G;  1K8A G;  5DM7 E;  2CQL A;  1YJW E;  2QA4 E;  1VQ8 E;  1RL6 A;  1Q7Y G;  4IO9 E;  3CMA E;  4WFA E;  1JJ2 E;  3CCM E;  4WFB E;  3CF5 E;  3PIP E;  3CCQ E;  5JVH E;  3CCR E;  1YJN E;  1W2B E;  2OTL E;  1VQN E;  5HL7 E;  3CPW E;  1Q81 G;  1M1K G;  1KD1 G;  3CCV E;  3CME E;  1VQK E;  1VQL E;  1KQS E;  3J7Z G;  3I55 E;  1VQ7 E;  1Q82 G;  3CCJ E;  5GAE G;  4WFN E;  1N8R G;  2QEX E;  1VQ6 E;  3CCS E;  4UY8 G;  3G71 E;  3OW2 E;  1VQP E;  3CD6 E;  5MLC H;  5GAG G;  5GAD G;  1VQM E;  1S72 E;  1QVF E;  3CC2 E;  1YJ9 E;  4WCE E;  3G4S E;  3PIO E;  3CCE E;  4WF9 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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