3CCRE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccrE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccrE01
1K73G 5HL7E 5GAGG 1N8RG 4IO9E 3PIPE 3CF5E 3CCVE 1YIJE 1YJWE 4WFBE 3CCRE 1S72E 1QVFE 1W2BE 4WF9E 1YJ9E 3CCJE 4WCEE 4IOCE 1YITE 5GADG 5GAHG 1VQLE 2ZJPE 3CMAE 1VQNE 3CCEE 3CPWE 1YHQE 1QVGE 5MLCH 2ZJQE 3G4SE 3CC4E 5AN9B 2QEXE 1YI2E 1JJ2E 3CC2E 5JVHE 1M90G 3CMEE 1Q82G 3CD6E 3CCLE 5GAEG 3I56E 1KD1G 3CCUE 1Q81G 1VQ4E 3CXCE 1YJNE 3G6EE 3G71E 4U67E 3OW2E 2OTLE 1Q7YG 1VQ9E 1VQME 2OTJE 1VQ7E 3J7ZG 3I55E 3DLLE 3CC7E 1VQ5E 4WFAE 5H1SI 3CCME 1NJIG 1VQ6E 5JVGE 3PIOE 5DM7E 1M1KG 2ZJRE 2CQLA 1VQ8E 4IOAE 1K9MG 3CCSE 1K8AG 1KQSE 4WFNE 1VQPE 1KC8G 1RL6A 1VQKE 2QA4E 5DM6E 1Q86G 1VQOE 3CCQE 4UY8G
chains in the Genus database with same CATH superfamily
1K73G 5HL7E 5GAGG 1N8RG 4IO9E 3PIPE 3CF5E 2HKDA 3CCVE 1YIJE 1YJWE 5B3MO 5B10O 4WFBE 3CCRE 1S72E 1QVFE 1W2BE 4WF9E 1YJ9E 3CCJE 4WCEE 4IOCE 1YITE 2OY5O 2OY7A 5GADG 5GAHG 1VQLE 2ZJPE 3CMAE 2OY8A 1FJ1E 1VQNE 3CCEE 3CPWE 1YHQE 1QVGE 2PI3O 2FKJA 5MLCH 2ZJQE 3G4SE 3CC4E 5B2AO 5AN9B 2QEXE 1YI2E 1JJ2E 3CC2E 5JVHE 1M90G 3CMEE 2I5ZO 1Q82G 2G8CO 3CD6E 3CCLE 5GAEG 3I56E 2OY1O 1KD1G 3CCUE 1Q81G 1VQ4E 3CXCE 1YJNE 2OYBO 2OL7A 2I5VO 1OSPO 3AUMO 3G6EE 3G71E 5B11O 3CKFA 4U67E 3OW2E 2OTLE 2OL6O 3IG9A 1Q7YG 1VQ9E 1VQME 2OTJE 1VQ7E 3J7ZG 3I55E 3DLLE 3CC7E 1VQ5E 4WFAE 1P4PA 5H1SI 3CCME 1NJIG 1VQ6E 5JVGE 3PIOE 5DM7E 1M1KG 2ZJRE 2CQLA 1VQ8E 4IOAE 1K9MG 3CCSE 1K8AG 1KQSE 4WFNE 1VQPE 1KC8G 1RL6A 1RJLC 3CKGA 1VQKE 2QA4E 5DM6E 3IGEA 1Q86G 1VQOE 3CCQE 2FKGA 2OL8O 2AF5A 4UY8G 3EC5A
chains in the Genus database with same CATH topology
1K73G 5HL7E 5GAGG 1N8RG 4IO9E 3PIPE 3CF5E 3CCVE 1YIJE 1YJWE 4WFBE 3CCRE 1S72E 1QVFE 1W2BE 4WF9E 1YJ9E 3CCJE 4WCEE 4IOCE 1YITE 5GADG 5GAHG 1VQLE 2ZJPE 3CMAE 1VQNE 3CCEE 3CPWE 1YHQE 1QVGE 5MLCH 2ZJQE 3G4SE 3CC4E 5AN9B 2QEXE 1YI2E 1JJ2E 3CC2E 5JVHE 1M90G 3CMEE 1Q82G 3CD6E 3CCLE 5GAEG 3I56E 1KD1G 3CCUE 1Q81G 1VQ4E 3CXCE 1YJNE 3G6EE 3G71E 4U67E 3OW2E 2OTLE 1Q7YG 1VQ9E 1VQME 2OTJE 1VQ7E 3J7ZG 3I55E 3DLLE 3CC7E 1VQ5E 4WFAE 5H1SI 3CCME 1NJIG 1VQ6E 5JVGE 3PIOE 5DM7E 1M1KG 2ZJRE 2CQLA 1VQ8E 4IOAE 1K9MG 3CCSE 1K8AG 1KQSE 4WFNE 1VQPE 1KC8G 1RL6A 1VQKE 2QA4E 5DM6E 1Q86G 1VQOE 3CCQE 4UY8G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K73 G;  5HL7 E;  5GAG G;  1N8R G;  4IO9 E;  3PIP E;  3CF5 E;  3CCV E;  1YIJ E;  1YJW E;  4WFB E;  3CCR E;  1S72 E;  1QVF E;  1W2B E;  4WF9 E;  1YJ9 E;  3CCJ E;  4WCE E;  4IOC E;  1YIT E;  5GAD G;  5GAH G;  1VQL E;  2ZJP E;  3CMA E;  1VQN E;  3CCE E;  3CPW E;  1YHQ E;  1QVG E;  5MLC H;  2ZJQ E;  3G4S E;  3CC4 E;  5AN9 B;  2QEX E;  1YI2 E;  1JJ2 E;  3CC2 E;  5JVH E;  1M90 G;  3CME E;  1Q82 G;  3CD6 E;  3CCL E;  5GAE G;  3I56 E;  1KD1 G;  3CCU E;  1Q81 G;  1VQ4 E;  3CXC E;  1YJN E;  3G6E E;  3G71 E;  4U67 E;  3OW2 E;  2OTL E;  1Q7Y G;  1VQ9 E;  1VQM E;  2OTJ E;  1VQ7 E;  3J7Z G;  3I55 E;  3DLL E;  3CC7 E;  1VQ5 E;  4WFA E;  5H1S I;  3CCM E;  1NJI G;  1VQ6 E;  5JVG E;  3PIO E;  5DM7 E;  1M1K G;  2ZJR E;  2CQL A;  1VQ8 E;  4IOA E;  1K9M G;  3CCS E;  1K8A G;  1KQS E;  4WFN E;  1VQP E;  1KC8 G;  1RL6 A;  1VQK E;  2QA4 E;  5DM6 E;  1Q86 G;  1VQO E;  3CCQ E;  4UY8 G; 
#chains in the Genus database with same CATH topology
 1K73 G;  5HL7 E;  5GAG G;  1N8R G;  4IO9 E;  3PIP E;  3CF5 E;  2HKD A;  3CCV E;  1YIJ E;  1YJW E;  5B3M O;  5B10 O;  4WFB E;  3CCR E;  1S72 E;  1QVF E;  1W2B E;  4WF9 E;  1YJ9 E;  3CCJ E;  4WCE E;  4IOC E;  1YIT E;  2OY5 O;  2OY7 A;  5GAD G;  5GAH G;  1VQL E;  2ZJP E;  3CMA E;  2OY8 A;  1FJ1 E;  1VQN E;  3CCE E;  3CPW E;  1YHQ E;  1QVG E;  2PI3 O;  2FKJ A;  5MLC H;  2ZJQ E;  3G4S E;  3CC4 E;  5B2A O;  5AN9 B;  2QEX E;  1YI2 E;  1JJ2 E;  3CC2 E;  5JVH E;  1M90 G;  3CME E;  2I5Z O;  1Q82 G;  2G8C O;  3CD6 E;  3CCL E;  5GAE G;  3I56 E;  2OY1 O;  1KD1 G;  3CCU E;  1Q81 G;  1VQ4 E;  3CXC E;  1YJN E;  2OYB O;  2OL7 A;  2I5V O;  1OSP O;  3AUM O;  3G6E E;  3G71 E;  5B11 O;  3CKF A;  4U67 E;  3OW2 E;  2OTL E;  2OL6 O;  3IG9 A;  1Q7Y G;  1VQ9 E;  1VQM E;  2OTJ E;  1VQ7 E;  3J7Z G;  3I55 E;  3DLL E;  3CC7 E;  1VQ5 E;  4WFA E;  1P4P A;  5H1S I;  3CCM E;  1NJI G;  1VQ6 E;  5JVG E;  3PIO E;  5DM7 E;  1M1K G;  2ZJR E;  2CQL A;  1VQ8 E;  4IOA E;  1K9M G;  3CCS E;  1K8A G;  1KQS E;  4WFN E;  1VQP E;  1KC8 G;  1RL6 A;  1RJL C;  3CKG A;  1VQK E;  2QA4 E;  5DM6 E;  3IGE A;  1Q86 G;  1VQO E;  3CCQ E;  2FKG A;  2OL8 O;  2AF5 A;  4UY8 G;  3EC5 A; 
#chains in the Genus database with same CATH homology
 1K73 G;  5HL7 E;  5GAG G;  1N8R G;  4IO9 E;  3PIP E;  3CF5 E;  3CCV E;  1YIJ E;  1YJW E;  4WFB E;  3CCR E;  1S72 E;  1QVF E;  1W2B E;  4WF9 E;  1YJ9 E;  3CCJ E;  4WCE E;  4IOC E;  1YIT E;  5GAD G;  5GAH G;  1VQL E;  2ZJP E;  3CMA E;  1VQN E;  3CCE E;  3CPW E;  1YHQ E;  1QVG E;  5MLC H;  2ZJQ E;  3G4S E;  3CC4 E;  5AN9 B;  2QEX E;  1YI2 E;  1JJ2 E;  3CC2 E;  5JVH E;  1M90 G;  3CME E;  1Q82 G;  3CD6 E;  3CCL E;  5GAE G;  3I56 E;  1KD1 G;  3CCU E;  1Q81 G;  1VQ4 E;  3CXC E;  1YJN E;  3G6E E;  3G71 E;  4U67 E;  3OW2 E;  2OTL E;  1Q7Y G;  1VQ9 E;  1VQM E;  2OTJ E;  1VQ7 E;  3J7Z G;  3I55 E;  3DLL E;  3CC7 E;  1VQ5 E;  4WFA E;  5H1S I;  3CCM E;  1NJI G;  1VQ6 E;  5JVG E;  3PIO E;  5DM7 E;  1M1K G;  2ZJR E;  2CQL A;  1VQ8 E;  4IOA E;  1K9M G;  3CCS E;  1K8A G;  1KQS E;  4WFN E;  1VQP E;  1KC8 G;  1RL6 A;  1VQK E;  2QA4 E;  5DM6 E;  1Q86 G;  1VQO E;  3CCQ E;  4UY8 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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