3CCUE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccuE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccuE01
2OTJE 3CCSE 1Q86G 1VQ9E 1VQ5E 4UY8G 3G71E 1YITE 3OW2E 1VQKE 1NJIG 1YJWE 1K8AG 1YHQE 1VQOE 1YJ9E 4U67E 2ZJQE 3I55E 5HL7E 5GAHG 1Q7YG 5MLCH 3CCME 5AN9B 5GAGG 4IOCE 4WFNE 3PIPE 4WFBE 3CCVE 3DLLE 2ZJPE 1VQ8E 3CCEE 3G4SE 3CCUE 3CC2E 5JVHE 1N8RG 1KD1G 3CMAE 4IOAE 3CCQE 4IO9E 1VQME 3CC7E 1YJNE 1K9MG 4WCEE 1JJ2E 1YI2E 3PIOE 1S72E 3CXCE 3CPWE 1M90G 2QA4E 2OTLE 1VQ4E 1KQSE 1QVGE 5JVGE 1VQLE 3G6EE 1VQNE 1VQPE 5DM7E 5GADG 1W2BE 1M1KG 2QEXE 3CD6E 3I56E 1RL6A 3CCRE 4WF9E 1Q81G 1KC8G 4WFAE 5H1SI 3CF5E 2ZJRE 3CC4E 5DM6E 1VQ6E 1K73G 3CCLE 5GAEG 2CQLA 1Q82G 1QVFE 1VQ7E 3CCJE 3J7ZG 3CMEE 1YIJE
chains in the Genus database with same CATH superfamily
2OTJE 3CCSE 1Q86G 1VQ9E 1VQ5E 4UY8G 3G71E 1YITE 3OW2E 5B3MO 1VQKE 2OYBO 1NJIG 1YJWE 1K8AG 2FKGA 1YHQE 1VQOE 1YJ9E 4U67E 2OY7A 2ZJQE 2OL7A 2OY1O 2I5VO 5HL7E 5GAHG 3I55E 2FKJA 5B11O 1Q7YG 5MLCH 1RJLC 3CCME 5AN9B 5GAGG 3EC5A 4IOCE 4WFNE 3PIPE 4WFBE 1P4PA 3CCVE 3DLLE 2AF5A 2ZJPE 1VQ8E 3CCEE 3G4SE 1OSPO 3CCUE 3CC2E 5JVHE 1N8RG 1KD1G 3CMAE 4IOAE 3CKGA 3CCQE 4IO9E 1VQME 3CC7E 1YJNE 1K9MG 4WCEE 3AUMO 3CKFA 1JJ2E 2OY5O 1YI2E 3PIOE 2HKDA 2OL8O 1S72E 3CXCE 2OL6O 3CPWE 1M90G 2QA4E 2OTLE 1VQ4E 3IG9A 1KQSE 1QVGE 2OY8A 5JVGE 1VQLE 3G6EE 5B10O 1VQNE 1VQPE 5DM7E 5GADG 1W2BE 3IGEA 2QEXE 1M1KG 3CD6E 3I56E 1RL6A 3CCRE 4WF9E 1Q81G 1KC8G 4WFAE 1FJ1E 5H1SI 2G8CO 3CF5E 2ZJRE 3CC4E 5DM6E 1VQ6E 1K73G 5B2AO 3CCLE 2CQLA 5GAEG 1Q82G 1QVFE 1VQ7E 3CCJE 3J7ZG 3CMEE 2I5ZO 2PI3O 1YIJE
chains in the Genus database with same CATH topology
2OTJE 3CCSE 1Q86G 1VQ9E 1VQ5E 4UY8G 3G71E 1YITE 3OW2E 1VQKE 1NJIG 1YJWE 1K8AG 1YHQE 1VQOE 1YJ9E 4U67E 2ZJQE 3I55E 5HL7E 5GAHG 1Q7YG 5MLCH 3CCME 5AN9B 5GAGG 4IOCE 4WFNE 3PIPE 4WFBE 3CCVE 3DLLE 2ZJPE 1VQ8E 3CCEE 3G4SE 3CCUE 3CC2E 5JVHE 1N8RG 1KD1G 3CMAE 4IOAE 3CCQE 4IO9E 1VQME 3CC7E 1YJNE 1K9MG 4WCEE 1JJ2E 1YI2E 3PIOE 1S72E 3CXCE 3CPWE 1M90G 2QA4E 2OTLE 1VQ4E 1KQSE 1QVGE 5JVGE 1VQLE 3G6EE 1VQNE 1VQPE 5DM7E 5GADG 1W2BE 1M1KG 2QEXE 3CD6E 3I56E 1RL6A 3CCRE 4WF9E 1Q81G 1KC8G 4WFAE 5H1SI 3CF5E 2ZJRE 3CC4E 5DM6E 1VQ6E 1K73G 3CCLE 5GAEG 2CQLA 1Q82G 1QVFE 1VQ7E 3CCJE 3J7ZG 3CMEE 1YIJE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTJ E;  3CCS E;  1Q86 G;  1VQ9 E;  1VQ5 E;  4UY8 G;  3G71 E;  1YIT E;  3OW2 E;  1VQK E;  1NJI G;  1YJW E;  1K8A G;  1YHQ E;  1VQO E;  1YJ9 E;  4U67 E;  2ZJQ E;  3I55 E;  5HL7 E;  5GAH G;  1Q7Y G;  5MLC H;  3CCM E;  5AN9 B;  5GAG G;  4IOC E;  4WFN E;  3PIP E;  4WFB E;  3CCV E;  3DLL E;  2ZJP E;  1VQ8 E;  3CCE E;  3G4S E;  3CCU E;  3CC2 E;  5JVH E;  1N8R G;  1KD1 G;  3CMA E;  4IOA E;  3CCQ E;  4IO9 E;  1VQM E;  3CC7 E;  1YJN E;  1K9M G;  4WCE E;  1JJ2 E;  1YI2 E;  3PIO E;  1S72 E;  3CXC E;  3CPW E;  1M90 G;  2QA4 E;  2OTL E;  1VQ4 E;  1KQS E;  1QVG E;  5JVG E;  1VQL E;  3G6E E;  1VQN E;  1VQP E;  5DM7 E;  5GAD G;  1W2B E;  1M1K G;  2QEX E;  3CD6 E;  3I56 E;  1RL6 A;  3CCR E;  4WF9 E;  1Q81 G;  1KC8 G;  4WFA E;  5H1S I;  3CF5 E;  2ZJR E;  3CC4 E;  5DM6 E;  1VQ6 E;  1K73 G;  3CCL E;  5GAE G;  2CQL A;  1Q82 G;  1QVF E;  1VQ7 E;  3CCJ E;  3J7Z G;  3CME E;  1YIJ E; 
#chains in the Genus database with same CATH topology
 2OTJ E;  3CCS E;  1Q86 G;  1VQ9 E;  1VQ5 E;  4UY8 G;  3G71 E;  1YIT E;  3OW2 E;  5B3M O;  1VQK E;  2OYB O;  1NJI G;  1YJW E;  1K8A G;  2FKG A;  1YHQ E;  1VQO E;  1YJ9 E;  4U67 E;  2OY7 A;  2ZJQ E;  2OL7 A;  2OY1 O;  2I5V O;  5HL7 E;  5GAH G;  3I55 E;  2FKJ A;  5B11 O;  1Q7Y G;  5MLC H;  1RJL C;  3CCM E;  5AN9 B;  5GAG G;  3EC5 A;  4IOC E;  4WFN E;  3PIP E;  4WFB E;  1P4P A;  3CCV E;  3DLL E;  2AF5 A;  2ZJP E;  1VQ8 E;  3CCE E;  3G4S E;  1OSP O;  3CCU E;  3CC2 E;  5JVH E;  1N8R G;  1KD1 G;  3CMA E;  4IOA E;  3CKG A;  3CCQ E;  4IO9 E;  1VQM E;  3CC7 E;  1YJN E;  1K9M G;  4WCE E;  3AUM O;  3CKF A;  1JJ2 E;  2OY5 O;  1YI2 E;  3PIO E;  2HKD A;  2OL8 O;  1S72 E;  3CXC E;  2OL6 O;  3CPW E;  1M90 G;  2QA4 E;  2OTL E;  1VQ4 E;  3IG9 A;  1KQS E;  1QVG E;  2OY8 A;  5JVG E;  1VQL E;  3G6E E;  5B10 O;  1VQN E;  1VQP E;  5DM7 E;  5GAD G;  1W2B E;  3IGE A;  2QEX E;  1M1K G;  3CD6 E;  3I56 E;  1RL6 A;  3CCR E;  4WF9 E;  1Q81 G;  1KC8 G;  4WFA E;  1FJ1 E;  5H1S I;  2G8C O;  3CF5 E;  2ZJR E;  3CC4 E;  5DM6 E;  1VQ6 E;  1K73 G;  5B2A O;  3CCL E;  2CQL A;  5GAE G;  1Q82 G;  1QVF E;  1VQ7 E;  3CCJ E;  3J7Z G;  3CME E;  2I5Z O;  2PI3 O;  1YIJ E; 
#chains in the Genus database with same CATH homology
 2OTJ E;  3CCS E;  1Q86 G;  1VQ9 E;  1VQ5 E;  4UY8 G;  3G71 E;  1YIT E;  3OW2 E;  1VQK E;  1NJI G;  1YJW E;  1K8A G;  1YHQ E;  1VQO E;  1YJ9 E;  4U67 E;  2ZJQ E;  3I55 E;  5HL7 E;  5GAH G;  1Q7Y G;  5MLC H;  3CCM E;  5AN9 B;  5GAG G;  4IOC E;  4WFN E;  3PIP E;  4WFB E;  3CCV E;  3DLL E;  2ZJP E;  1VQ8 E;  3CCE E;  3G4S E;  3CCU E;  3CC2 E;  5JVH E;  1N8R G;  1KD1 G;  3CMA E;  4IOA E;  3CCQ E;  4IO9 E;  1VQM E;  3CC7 E;  1YJN E;  1K9M G;  4WCE E;  1JJ2 E;  1YI2 E;  3PIO E;  1S72 E;  3CXC E;  3CPW E;  1M90 G;  2QA4 E;  2OTL E;  1VQ4 E;  1KQS E;  1QVG E;  5JVG E;  1VQL E;  3G6E E;  1VQN E;  1VQP E;  5DM7 E;  5GAD G;  1W2B E;  1M1K G;  2QEX E;  3CD6 E;  3I56 E;  1RL6 A;  3CCR E;  4WF9 E;  1Q81 G;  1KC8 G;  4WFA E;  5H1S I;  3CF5 E;  2ZJR E;  3CC4 E;  5DM6 E;  1VQ6 E;  1K73 G;  3CCL E;  5GAE G;  2CQL A;  1Q82 G;  1QVF E;  1VQ7 E;  3CCJ E;  3J7Z G;  3CME E;  1YIJ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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