3CCVE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccvE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3ccvE01
5JVHE 1RL6A 1YITE 3CCME 1QVFE 2ZJRE 4IOAE 1Q82G 1M90G 3PIOE 1VQ9E 1KQSE 3CCSE 1K9MG 3G71E 1K8AG 3CXCE 3CCLE 1VQ6E 5HL7E 3CPWE 5JVGE 1YHQE 1JJ2E 2ZJPE 2QA4E 3CMAE 1YI2E 3G6EE 3PIPE 1VQKE 3CC7E 1VQME 2QEXE 3CCVE 3G4SE 3CMEE 5GAEG 1VQPE 1S72E 5MLCH 2CQLA 3CCQE 3J7ZG 3DLLE 5DM6E 3CF5E 1VQ7E 1W2BE 3CCJE 5GADG 4UY8G 3I55E 1QVGE 1VQ4E 1K73G 1VQNE 1YJ9E 4WCEE 1Q81G 1YIJE 3CCEE 5GAGG 1KC8G 1YJWE 1VQOE 1N8RG 5GAHG 3I56E 1YJNE 4WFAE 3CD6E 4IOCE 3CCUE 1VQ8E 3CCRE 1Q7YG 3CC4E 4IO9E 4WF9E 4U67E 1VQ5E 5H1SI 2ZJQE 1NJIG 4WFBE 1VQLE 1KD1G 3OW2E 5AN9B 2OTLE 1Q86G 2OTJE 4WFNE 1M1KG 3CC2E 5DM7E
chains in the Genus database with same CATH superfamily
5JVHE 1RL6A 1YITE 3CCME 1QVFE 2PI3O 5B10O 2ZJRE 4IOAE 1Q82G 1M90G 2OY8A 3PIOE 1VQ9E 1KQSE 3CCSE 5B3MO 1RJLC 1K9MG 3G71E 1K8AG 3CXCE 2OYBO 3CCLE 3EC5A 5B11O 1VQ6E 5HL7E 3CPWE 5JVGE 1YHQE 1JJ2E 1FJ1E 2ZJPE 2QA4E 3CMAE 1YI2E 3G6EE 3PIPE 1VQKE 2FKGA 3CC7E 1VQME 2QEXE 3CCVE 3G4SE 3CMEE 2I5ZO 5GAEG 1VQPE 3IGEA 1S72E 1OSPO 5MLCH 2CQLA 3CCQE 3J7ZG 3IG9A 2OL7A 3DLLE 2OL8O 5DM6E 3CF5E 1VQ7E 1W2BE 5B2AO 3CCJE 2G8CO 5GADG 3CKFA 2OY5O 2FKJA 4UY8G 3I55E 1QVGE 2HKDA 3AUMO 1P4PA 1VQ4E 1K73G 1VQNE 1YJ9E 4WCEE 1Q81G 1YIJE 3CCEE 5GAGG 1KC8G 1YJWE 2OY1O 3CKGA 1VQOE 1N8RG 2OL6O 5GAHG 3I56E 1YJNE 4WFAE 3CD6E 2OY7A 4IOCE 3CCUE 1VQ8E 3CCRE 1Q7YG 3CC4E 4IO9E 4WF9E 4U67E 1VQ5E 5H1SI 2ZJQE 1NJIG 4WFBE 1VQLE 1KD1G 3OW2E 2AF5A 5AN9B 2OTLE 1Q86G 2OTJE 4WFNE 1M1KG 3CC2E 5DM7E 2I5VO
chains in the Genus database with same CATH topology
5JVHE 1RL6A 1YITE 3CCME 1QVFE 2ZJRE 4IOAE 1Q82G 1M90G 3PIOE 1VQ9E 1KQSE 3CCSE 1K9MG 3G71E 1K8AG 3CXCE 3CCLE 1VQ6E 5HL7E 3CPWE 5JVGE 1YHQE 1JJ2E 2ZJPE 2QA4E 3CMAE 1YI2E 3G6EE 3PIPE 1VQKE 3CC7E 1VQME 2QEXE 3CCVE 3G4SE 3CMEE 5GAEG 1VQPE 1S72E 5MLCH 2CQLA 3CCQE 3J7ZG 3DLLE 5DM6E 3CF5E 1VQ7E 1W2BE 3CCJE 5GADG 4UY8G 3I55E 1QVGE 1VQ4E 1K73G 1VQNE 1YJ9E 4WCEE 1Q81G 1YIJE 3CCEE 5GAGG 1KC8G 1YJWE 1VQOE 1N8RG 5GAHG 3I56E 1YJNE 4WFAE 3CD6E 4IOCE 3CCUE 1VQ8E 3CCRE 1Q7YG 3CC4E 4IO9E 4WF9E 4U67E 1VQ5E 5H1SI 2ZJQE 1NJIG 4WFBE 1VQLE 1KD1G 3OW2E 5AN9B 2OTLE 1Q86G 2OTJE 4WFNE 1M1KG 3CC2E 5DM7E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVH E;  1RL6 A;  1YIT E;  3CCM E;  1QVF E;  2ZJR E;  4IOA E;  1Q82 G;  1M90 G;  3PIO E;  1VQ9 E;  1KQS E;  3CCS E;  1K9M G;  3G71 E;  1K8A G;  3CXC E;  3CCL E;  1VQ6 E;  5HL7 E;  3CPW E;  5JVG E;  1YHQ E;  1JJ2 E;  2ZJP E;  2QA4 E;  3CMA E;  1YI2 E;  3G6E E;  3PIP E;  1VQK E;  3CC7 E;  1VQM E;  2QEX E;  3CCV E;  3G4S E;  3CME E;  5GAE G;  1VQP E;  1S72 E;  5MLC H;  2CQL A;  3CCQ E;  3J7Z G;  3DLL E;  5DM6 E;  3CF5 E;  1VQ7 E;  1W2B E;  3CCJ E;  5GAD G;  4UY8 G;  3I55 E;  1QVG E;  1VQ4 E;  1K73 G;  1VQN E;  1YJ9 E;  4WCE E;  1Q81 G;  1YIJ E;  3CCE E;  5GAG G;  1KC8 G;  1YJW E;  1VQO E;  1N8R G;  5GAH G;  3I56 E;  1YJN E;  4WFA E;  3CD6 E;  4IOC E;  3CCU E;  1VQ8 E;  3CCR E;  1Q7Y G;  3CC4 E;  4IO9 E;  4WF9 E;  4U67 E;  1VQ5 E;  5H1S I;  2ZJQ E;  1NJI G;  4WFB E;  1VQL E;  1KD1 G;  3OW2 E;  5AN9 B;  2OTL E;  1Q86 G;  2OTJ E;  4WFN E;  1M1K G;  3CC2 E;  5DM7 E; 
#chains in the Genus database with same CATH topology
 5JVH E;  1RL6 A;  1YIT E;  3CCM E;  1QVF E;  2PI3 O;  5B10 O;  2ZJR E;  4IOA E;  1Q82 G;  1M90 G;  2OY8 A;  3PIO E;  1VQ9 E;  1KQS E;  3CCS E;  5B3M O;  1RJL C;  1K9M G;  3G71 E;  1K8A G;  3CXC E;  2OYB O;  3CCL E;  3EC5 A;  5B11 O;  1VQ6 E;  5HL7 E;  3CPW E;  5JVG E;  1YHQ E;  1JJ2 E;  1FJ1 E;  2ZJP E;  2QA4 E;  3CMA E;  1YI2 E;  3G6E E;  3PIP E;  1VQK E;  2FKG A;  3CC7 E;  1VQM E;  2QEX E;  3CCV E;  3G4S E;  3CME E;  2I5Z O;  5GAE G;  1VQP E;  3IGE A;  1S72 E;  1OSP O;  5MLC H;  2CQL A;  3CCQ E;  3J7Z G;  3IG9 A;  2OL7 A;  3DLL E;  2OL8 O;  5DM6 E;  3CF5 E;  1VQ7 E;  1W2B E;  5B2A O;  3CCJ E;  2G8C O;  5GAD G;  3CKF A;  2OY5 O;  2FKJ A;  4UY8 G;  3I55 E;  1QVG E;  2HKD A;  3AUM O;  1P4P A;  1VQ4 E;  1K73 G;  1VQN E;  1YJ9 E;  4WCE E;  1Q81 G;  1YIJ E;  3CCE E;  5GAG G;  1KC8 G;  1YJW E;  2OY1 O;  3CKG A;  1VQO E;  1N8R G;  2OL6 O;  5GAH G;  3I56 E;  1YJN E;  4WFA E;  3CD6 E;  2OY7 A;  4IOC E;  3CCU E;  1VQ8 E;  3CCR E;  1Q7Y G;  3CC4 E;  4IO9 E;  4WF9 E;  4U67 E;  1VQ5 E;  5H1S I;  2ZJQ E;  1NJI G;  4WFB E;  1VQL E;  1KD1 G;  3OW2 E;  2AF5 A;  5AN9 B;  2OTL E;  1Q86 G;  2OTJ E;  4WFN E;  1M1K G;  3CC2 E;  5DM7 E;  2I5V O; 
#chains in the Genus database with same CATH homology
 5JVH E;  1RL6 A;  1YIT E;  3CCM E;  1QVF E;  2ZJR E;  4IOA E;  1Q82 G;  1M90 G;  3PIO E;  1VQ9 E;  1KQS E;  3CCS E;  1K9M G;  3G71 E;  1K8A G;  3CXC E;  3CCL E;  1VQ6 E;  5HL7 E;  3CPW E;  5JVG E;  1YHQ E;  1JJ2 E;  2ZJP E;  2QA4 E;  3CMA E;  1YI2 E;  3G6E E;  3PIP E;  1VQK E;  3CC7 E;  1VQM E;  2QEX E;  3CCV E;  3G4S E;  3CME E;  5GAE G;  1VQP E;  1S72 E;  5MLC H;  2CQL A;  3CCQ E;  3J7Z G;  3DLL E;  5DM6 E;  3CF5 E;  1VQ7 E;  1W2B E;  3CCJ E;  5GAD G;  4UY8 G;  3I55 E;  1QVG E;  1VQ4 E;  1K73 G;  1VQN E;  1YJ9 E;  4WCE E;  1Q81 G;  1YIJ E;  3CCE E;  5GAG G;  1KC8 G;  1YJW E;  1VQO E;  1N8R G;  5GAH G;  3I56 E;  1YJN E;  4WFA E;  3CD6 E;  4IOC E;  3CCU E;  1VQ8 E;  3CCR E;  1Q7Y G;  3CC4 E;  4IO9 E;  4WF9 E;  4U67 E;  1VQ5 E;  5H1S I;  2ZJQ E;  1NJI G;  4WFB E;  1VQL E;  1KD1 G;  3OW2 E;  5AN9 B;  2OTL E;  1Q86 G;  2OTJ E;  4WFN E;  1M1K G;  3CC2 E;  5DM7 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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