3CPWE

The structure of the antibiotic linezolid bound to the large ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cpwE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cpwE01
1M90G 1Q81G 1VQKE 3CCEE 1KD1G 4UY8G 1VQ7E 1YJNE 1YJWE 1KC8G 3CF5E 1YJ9E 3CD6E 1QVFE 4IOCE 2ZJQE 1S72E 5GAEG 3CC4E 1VQLE 2ZJRE 2QA4E 1YI2E 5GAGG 3G4SE 5DM6E 4WCEE 1NJIG 3CCRE 4IOAE 3CXCE 1Q86G 5JVHE 1RL6A 1VQ6E 3PIOE 3I56E 4WFAE 3I55E 1VQ4E 3CPWE 1VQPE 1VQNE 3CCME 1VQOE 3CMAE 1KQSE 3CMEE 1VQ9E 1YITE 1K9MG 5HL7E 3OW2E 1K8AG 3PIPE 3CCUE 2CQLA 2OTJE 1VQ8E 4WFNE 1K73G 4IO9E 3G71E 3DLLE 1N8RG 1JJ2E 3CCQE 1VQME 1YIJE 3CC7E 4WFBE 1VQ5E 2QEXE 3CCVE 1QVGE 2OTLE 1Q82G 4U67E 2ZJPE 4WF9E 3J7ZG 5MLCH 5AN9B 1Q7YG 3CCLE 1W2BE 5GAHG 5JVGE 3CCSE 3CCJE 3G6EE 1M1KG 5DM7E 3CC2E 1YHQE 5GADG 5H1SI
chains in the Genus database with same CATH superfamily
1M90G 1Q81G 1VQKE 3CCEE 1KD1G 2I5ZO 4UY8G 1VQ7E 1YJNE 1YJWE 1KC8G 3CF5E 1YJ9E 3CD6E 1QVFE 2FKJA 1FJ1E 4IOCE 2ZJQE 1S72E 2AF5A 5GAEG 3CC4E 5B11O 2ZJRE 2OY7A 1VQLE 2QA4E 2HKDA 1YI2E 5GAGG 3IG9A 3G4SE 5DM6E 1OSPO 4WCEE 1NJIG 2G8CO 3EC5A 3CCRE 2PI3O 3CXCE 4IOAE 1Q86G 1RJLC 5JVHE 2FKGA 5B3MO 1RL6A 1P4PA 1VQ6E 2OY5O 3PIOE 3I56E 4WFAE 3I55E 1VQ4E 3CPWE 1VQPE 1VQNE 3CCME 1VQOE 3CMAE 2OL6O 1KQSE 3CMEE 1VQ9E 1YITE 2OL8O 1K9MG 5HL7E 3OW2E 3IGEA 1K8AG 3PIPE 3CCUE 2CQLA 2OTJE 1VQ8E 4WFNE 1K73G 4IO9E 3G71E 2OYBO 3DLLE 1N8RG 1JJ2E 3CCQE 2I5VO 2OL7A 1VQME 3CKFA 5B2AO 1YIJE 3CC7E 4WFBE 2OY1O 1VQ5E 3CKGA 2QEXE 3CCVE 1QVGE 2OTLE 1Q82G 3AUMO 4U67E 2ZJPE 4WF9E 3J7ZG 2OY8A 5MLCH 5AN9B 1Q7YG 3CCLE 1W2BE 5GAHG 5JVGE 3CCSE 3CCJE 3G6EE 5B10O 1M1KG 5DM7E 3CC2E 1YHQE 5GADG 5H1SI
chains in the Genus database with same CATH topology
1M90G 1Q81G 1VQKE 3CCEE 1KD1G 4UY8G 1VQ7E 1YJNE 1YJWE 1KC8G 3CF5E 1YJ9E 3CD6E 1QVFE 4IOCE 2ZJQE 1S72E 5GAEG 3CC4E 1VQLE 2ZJRE 2QA4E 1YI2E 5GAGG 3G4SE 5DM6E 4WCEE 1NJIG 3CCRE 4IOAE 3CXCE 1Q86G 5JVHE 1RL6A 1VQ6E 3PIOE 3I56E 4WFAE 3I55E 1VQ4E 3CPWE 1VQPE 1VQNE 3CCME 1VQOE 3CMAE 1KQSE 3CMEE 1VQ9E 1YITE 1K9MG 5HL7E 3OW2E 1K8AG 3PIPE 3CCUE 2CQLA 2OTJE 1VQ8E 4WFNE 1K73G 4IO9E 3G71E 3DLLE 1N8RG 1JJ2E 3CCQE 1VQME 1YIJE 3CC7E 4WFBE 1VQ5E 2QEXE 3CCVE 1QVGE 2OTLE 1Q82G 4U67E 2ZJPE 4WF9E 3J7ZG 5MLCH 5AN9B 1Q7YG 3CCLE 1W2BE 5GAHG 5JVGE 3CCSE 3CCJE 3G6EE 1M1KG 5DM7E 3CC2E 1YHQE 5GADG 5H1SI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 G;  1Q81 G;  1VQK E;  3CCE E;  1KD1 G;  4UY8 G;  1VQ7 E;  1YJN E;  1YJW E;  1KC8 G;  3CF5 E;  1YJ9 E;  3CD6 E;  1QVF E;  4IOC E;  2ZJQ E;  1S72 E;  5GAE G;  3CC4 E;  1VQL E;  2ZJR E;  2QA4 E;  1YI2 E;  5GAG G;  3G4S E;  5DM6 E;  4WCE E;  1NJI G;  3CCR E;  4IOA E;  3CXC E;  1Q86 G;  5JVH E;  1RL6 A;  1VQ6 E;  3PIO E;  3I56 E;  4WFA E;  3I55 E;  1VQ4 E;  3CPW E;  1VQP E;  1VQN E;  3CCM E;  1VQO E;  3CMA E;  1KQS E;  3CME E;  1VQ9 E;  1YIT E;  1K9M G;  5HL7 E;  3OW2 E;  1K8A G;  3PIP E;  3CCU E;  2CQL A;  2OTJ E;  1VQ8 E;  4WFN E;  1K73 G;  4IO9 E;  3G71 E;  3DLL E;  1N8R G;  1JJ2 E;  3CCQ E;  1VQM E;  1YIJ E;  3CC7 E;  4WFB E;  1VQ5 E;  2QEX E;  3CCV E;  1QVG E;  2OTL E;  1Q82 G;  4U67 E;  2ZJP E;  4WF9 E;  3J7Z G;  5MLC H;  5AN9 B;  1Q7Y G;  3CCL E;  1W2B E;  5GAH G;  5JVG E;  3CCS E;  3CCJ E;  3G6E E;  1M1K G;  5DM7 E;  3CC2 E;  1YHQ E;  5GAD G;  5H1S I; 
#chains in the Genus database with same CATH topology
 1M90 G;  1Q81 G;  1VQK E;  3CCE E;  1KD1 G;  2I5Z O;  4UY8 G;  1VQ7 E;  1YJN E;  1YJW E;  1KC8 G;  3CF5 E;  1YJ9 E;  3CD6 E;  1QVF E;  2FKJ A;  1FJ1 E;  4IOC E;  2ZJQ E;  1S72 E;  2AF5 A;  5GAE G;  3CC4 E;  5B11 O;  2ZJR E;  2OY7 A;  1VQL E;  2QA4 E;  2HKD A;  1YI2 E;  5GAG G;  3IG9 A;  3G4S E;  5DM6 E;  1OSP O;  4WCE E;  1NJI G;  2G8C O;  3EC5 A;  3CCR E;  2PI3 O;  3CXC E;  4IOA E;  1Q86 G;  1RJL C;  5JVH E;  2FKG A;  5B3M O;  1RL6 A;  1P4P A;  1VQ6 E;  2OY5 O;  3PIO E;  3I56 E;  4WFA E;  3I55 E;  1VQ4 E;  3CPW E;  1VQP E;  1VQN E;  3CCM E;  1VQO E;  3CMA E;  2OL6 O;  1KQS E;  3CME E;  1VQ9 E;  1YIT E;  2OL8 O;  1K9M G;  5HL7 E;  3OW2 E;  3IGE A;  1K8A G;  3PIP E;  3CCU E;  2CQL A;  2OTJ E;  1VQ8 E;  4WFN E;  1K73 G;  4IO9 E;  3G71 E;  2OYB O;  3DLL E;  1N8R G;  1JJ2 E;  3CCQ E;  2I5V O;  2OL7 A;  1VQM E;  3CKF A;  5B2A O;  1YIJ E;  3CC7 E;  4WFB E;  2OY1 O;  1VQ5 E;  3CKG A;  2QEX E;  3CCV E;  1QVG E;  2OTL E;  1Q82 G;  3AUM O;  4U67 E;  2ZJP E;  4WF9 E;  3J7Z G;  2OY8 A;  5MLC H;  5AN9 B;  1Q7Y G;  3CCL E;  1W2B E;  5GAH G;  5JVG E;  3CCS E;  3CCJ E;  3G6E E;  5B10 O;  1M1K G;  5DM7 E;  3CC2 E;  1YHQ E;  5GAD G;  5H1S I; 
#chains in the Genus database with same CATH homology
 1M90 G;  1Q81 G;  1VQK E;  3CCE E;  1KD1 G;  4UY8 G;  1VQ7 E;  1YJN E;  1YJW E;  1KC8 G;  3CF5 E;  1YJ9 E;  3CD6 E;  1QVF E;  4IOC E;  2ZJQ E;  1S72 E;  5GAE G;  3CC4 E;  1VQL E;  2ZJR E;  2QA4 E;  1YI2 E;  5GAG G;  3G4S E;  5DM6 E;  4WCE E;  1NJI G;  3CCR E;  4IOA E;  3CXC E;  1Q86 G;  5JVH E;  1RL6 A;  1VQ6 E;  3PIO E;  3I56 E;  4WFA E;  3I55 E;  1VQ4 E;  3CPW E;  1VQP E;  1VQN E;  3CCM E;  1VQO E;  3CMA E;  1KQS E;  3CME E;  1VQ9 E;  1YIT E;  1K9M G;  5HL7 E;  3OW2 E;  1K8A G;  3PIP E;  3CCU E;  2CQL A;  2OTJ E;  1VQ8 E;  4WFN E;  1K73 G;  4IO9 E;  3G71 E;  3DLL E;  1N8R G;  1JJ2 E;  3CCQ E;  1VQM E;  1YIJ E;  3CC7 E;  4WFB E;  1VQ5 E;  2QEX E;  3CCV E;  1QVG E;  2OTL E;  1Q82 G;  4U67 E;  2ZJP E;  4WF9 E;  3J7Z G;  5MLC H;  5AN9 B;  1Q7Y G;  3CCL E;  1W2B E;  5GAH G;  5JVG E;  3CCS E;  3CCJ E;  3G6E E;  1M1K G;  5DM7 E;  3CC2 E;  1YHQ E;  5GAD G;  5H1S I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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