3CXCE

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cxcE01
1VQ8E 3CCVE 1NJIG 5GADG 2QEXE 1RL6A 2ZJQE 1VQME 3CMEE 5H1SI 1Q86G 5GAEG 4WFAE 4WFNE 3CPWE 3CMAE 1KD1G 3CCJE 3CCQE 4WCEE 1Q82G 1VQKE 3G4SE 5JVGE 1VQOE 3CC4E 4IOAE 4WFBE 2OTLE 3PIOE 3CCEE 1K73G 3CD6E 3CCUE 3CCME 4U67E 3OW2E 5DM7E 1KC8G 1VQNE 4WF9E 1YJNE 2CQLA 1M1KG 3DLLE 1YI2E 3CC2E 3G6EE 4UY8G 1VQ6E 3CCRE 2QA4E 4IO9E 1YHQE 1K8AG 5JVHE 1S72E 1KQSE 1VQ7E 3J7ZG 1YITE 1QVGE 2ZJRE 1VQ9E 1K9MG 1YJ9E 1VQ4E 1YJWE 1VQ5E 3CF5E 1N8RG 3CCLE 1VQPE 3G71E 5AN9B 5HL7E 5MLCH 1W2BE 3CC7E 1YIJE 5DM6E 3CXCE 1M90G 4IOCE 2ZJPE 5GAGG 5GAHG 1Q7YG 1QVFE 3I56E 3I55E 1VQLE 3CCSE 1JJ2E 1Q81G 3PIPE 2OTJE
chains in the Genus database with same CATH superfamily
1VQ8E 3CCVE 1NJIG 2I5VO 5B11O 5GADG 2QEXE 1RL6A 1RJLC 2OY7A 1VQME 2ZJQE 3CMEE 5H1SI 1Q86G 5GAEG 4WFAE 4WFNE 3CPWE 2I5ZO 3CMAE 1KD1G 2OL6O 3CCJE 3CCQE 4WCEE 1Q82G 1VQKE 3G4SE 5JVGE 1VQOE 3CC4E 4IOAE 4WFBE 2OTLE 3PIOE 3CCEE 1K73G 1FJ1E 3CD6E 3CCUE 2G8CO 3CCME 4U67E 3OW2E 5DM7E 1KC8G 1VQNE 4WF9E 1YJNE 2CQLA 2FKGA 1M1KG 5B3MO 3DLLE 1YI2E 3CC2E 2OL8O 3G6EE 4UY8G 3AUMO 2HKDA 1VQ6E 2OY5O 3CCRE 2QA4E 4IO9E 2OYBO 1YHQE 2OY1O 1K8AG 5JVHE 1S72E 1KQSE 1VQ7E 3IG9A 3J7ZG 1YITE 1QVGE 3EC5A 2ZJRE 5B2AO 1VQ9E 1K9MG 1YJ9E 1VQ4E 1YJWE 1VQ5E 2AF5A 3CF5E 1N8RG 2OTJE 3CCLE 1VQPE 3G71E 3CKFA 2FKJA 1OSPO 5AN9B 5HL7E 5MLCH 1W2BE 2OY8A 3IGEA 3CC7E 1YIJE 3CKGA 5DM6E 1P4PA 3CXCE 1M90G 4IOCE 2ZJPE 5GAGG 5B10O 5GAHG 1Q7YG 1QVFE 3I56E 3I55E 1VQLE 3CCSE 1JJ2E 1Q81G 3PIPE 2PI3O 2OL7A
chains in the Genus database with same CATH topology
1VQ8E 3CCVE 1NJIG 5GADG 2QEXE 1RL6A 2ZJQE 1VQME 3CMEE 5H1SI 1Q86G 5GAEG 4WFAE 4WFNE 3CPWE 3CMAE 1KD1G 3CCJE 3CCQE 4WCEE 1Q82G 1VQKE 3G4SE 5JVGE 1VQOE 3CC4E 4IOAE 4WFBE 2OTLE 3PIOE 3CCEE 1K73G 3CD6E 3CCUE 3CCME 4U67E 3OW2E 5DM7E 1KC8G 1VQNE 4WF9E 1YJNE 2CQLA 1M1KG 3DLLE 1YI2E 3CC2E 3G6EE 4UY8G 1VQ6E 3CCRE 2QA4E 4IO9E 1YHQE 1K8AG 5JVHE 1S72E 1KQSE 1VQ7E 3J7ZG 1YITE 1QVGE 2ZJRE 1VQ9E 1K9MG 1YJ9E 1VQ4E 1YJWE 1VQ5E 3CF5E 1N8RG 3CCLE 1VQPE 3G71E 5AN9B 5HL7E 5MLCH 1W2BE 3CC7E 1YIJE 5DM6E 3CXCE 1M90G 4IOCE 2ZJPE 5GAGG 5GAHG 1Q7YG 1QVFE 3I56E 3I55E 1VQLE 3CCSE 1JJ2E 1Q81G 3PIPE 2OTJE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ8 E;  3CCV E;  1NJI G;  5GAD G;  2QEX E;  1RL6 A;  2ZJQ E;  1VQM E;  3CME E;  5H1S I;  1Q86 G;  5GAE G;  4WFA E;  4WFN E;  3CPW E;  3CMA E;  1KD1 G;  3CCJ E;  3CCQ E;  4WCE E;  1Q82 G;  1VQK E;  3G4S E;  5JVG E;  1VQO E;  3CC4 E;  4IOA E;  4WFB E;  2OTL E;  3PIO E;  3CCE E;  1K73 G;  3CD6 E;  3CCU E;  3CCM E;  4U67 E;  3OW2 E;  5DM7 E;  1KC8 G;  1VQN E;  4WF9 E;  1YJN E;  2CQL A;  1M1K G;  3DLL E;  1YI2 E;  3CC2 E;  3G6E E;  4UY8 G;  1VQ6 E;  3CCR E;  2QA4 E;  4IO9 E;  1YHQ E;  1K8A G;  5JVH E;  1S72 E;  1KQS E;  1VQ7 E;  3J7Z G;  1YIT E;  1QVG E;  2ZJR E;  1VQ9 E;  1K9M G;  1YJ9 E;  1VQ4 E;  1YJW E;  1VQ5 E;  3CF5 E;  1N8R G;  3CCL E;  1VQP E;  3G71 E;  5AN9 B;  5HL7 E;  5MLC H;  1W2B E;  3CC7 E;  1YIJ E;  5DM6 E;  3CXC E;  1M90 G;  4IOC E;  2ZJP E;  5GAG G;  5GAH G;  1Q7Y G;  1QVF E;  3I56 E;  3I55 E;  1VQL E;  3CCS E;  1JJ2 E;  1Q81 G;  3PIP E;  2OTJ E; 
#chains in the Genus database with same CATH topology
 1VQ8 E;  3CCV E;  1NJI G;  2I5V O;  5B11 O;  5GAD G;  2QEX E;  1RL6 A;  1RJL C;  2OY7 A;  1VQM E;  2ZJQ E;  3CME E;  5H1S I;  1Q86 G;  5GAE G;  4WFA E;  4WFN E;  3CPW E;  2I5Z O;  3CMA E;  1KD1 G;  2OL6 O;  3CCJ E;  3CCQ E;  4WCE E;  1Q82 G;  1VQK E;  3G4S E;  5JVG E;  1VQO E;  3CC4 E;  4IOA E;  4WFB E;  2OTL E;  3PIO E;  3CCE E;  1K73 G;  1FJ1 E;  3CD6 E;  3CCU E;  2G8C O;  3CCM E;  4U67 E;  3OW2 E;  5DM7 E;  1KC8 G;  1VQN E;  4WF9 E;  1YJN E;  2CQL A;  2FKG A;  1M1K G;  5B3M O;  3DLL E;  1YI2 E;  3CC2 E;  2OL8 O;  3G6E E;  4UY8 G;  3AUM O;  2HKD A;  1VQ6 E;  2OY5 O;  3CCR E;  2QA4 E;  4IO9 E;  2OYB O;  1YHQ E;  2OY1 O;  1K8A G;  5JVH E;  1S72 E;  1KQS E;  1VQ7 E;  3IG9 A;  3J7Z G;  1YIT E;  1QVG E;  3EC5 A;  2ZJR E;  5B2A O;  1VQ9 E;  1K9M G;  1YJ9 E;  1VQ4 E;  1YJW E;  1VQ5 E;  2AF5 A;  3CF5 E;  1N8R G;  2OTJ E;  3CCL E;  1VQP E;  3G71 E;  3CKF A;  2FKJ A;  1OSP O;  5AN9 B;  5HL7 E;  5MLC H;  1W2B E;  2OY8 A;  3IGE A;  3CC7 E;  1YIJ E;  3CKG A;  5DM6 E;  1P4P A;  3CXC E;  1M90 G;  4IOC E;  2ZJP E;  5GAG G;  5B10 O;  5GAH G;  1Q7Y G;  1QVF E;  3I56 E;  3I55 E;  1VQL E;  3CCS E;  1JJ2 E;  1Q81 G;  3PIP E;  2PI3 O;  2OL7 A; 
#chains in the Genus database with same CATH homology
 1VQ8 E;  3CCV E;  1NJI G;  5GAD G;  2QEX E;  1RL6 A;  2ZJQ E;  1VQM E;  3CME E;  5H1S I;  1Q86 G;  5GAE G;  4WFA E;  4WFN E;  3CPW E;  3CMA E;  1KD1 G;  3CCJ E;  3CCQ E;  4WCE E;  1Q82 G;  1VQK E;  3G4S E;  5JVG E;  1VQO E;  3CC4 E;  4IOA E;  4WFB E;  2OTL E;  3PIO E;  3CCE E;  1K73 G;  3CD6 E;  3CCU E;  3CCM E;  4U67 E;  3OW2 E;  5DM7 E;  1KC8 G;  1VQN E;  4WF9 E;  1YJN E;  2CQL A;  1M1K G;  3DLL E;  1YI2 E;  3CC2 E;  3G6E E;  4UY8 G;  1VQ6 E;  3CCR E;  2QA4 E;  4IO9 E;  1YHQ E;  1K8A G;  5JVH E;  1S72 E;  1KQS E;  1VQ7 E;  3J7Z G;  1YIT E;  1QVG E;  2ZJR E;  1VQ9 E;  1K9M G;  1YJ9 E;  1VQ4 E;  1YJW E;  1VQ5 E;  3CF5 E;  1N8R G;  3CCL E;  1VQP E;  3G71 E;  5AN9 B;  5HL7 E;  5MLC H;  1W2B E;  3CC7 E;  1YIJ E;  5DM6 E;  3CXC E;  1M90 G;  4IOC E;  2ZJP E;  5GAG G;  5GAH G;  1Q7Y G;  1QVF E;  3I56 E;  3I55 E;  1VQL E;  3CCS E;  1JJ2 E;  1Q81 G;  3PIP E;  2OTJ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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