3G4SE

Co-crystal structure of tiamulin bound to the large ribosomal subunit
Total Genus 32
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 32
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2009-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3g4sE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3g4sE01
1VQ9E 1VQME 1VQ8E 1YJWE 3G71E 3CCUE 4IO9E 4IOAE 3PIOE 3G6EE 3CPWE 1YI2E 2ZJRE 3CCRE 1YIJE 1K73G 1JJ2E 4UY8G 5H1SI 5HL7E 3CD6E 5MLCH 1VQLE 3I56E 1VQ5E 3PIPE 1N8RG 1KC8G 3CF5E 4WFBE 4WFAE 5GAGG 3CCEE 4WCEE 1QVGE 4WF9E 1VQPE 1KQSE 3DLLE 2ZJPE 5DM6E 3CC7E 4U67E 2OTJE 1YITE 1VQKE 5JVGE 3CCVE 1VQ7E 1Q81G 2QEXE 3CXCE 1S72E 3CCLE 1YJ9E 3CC4E 1YHQE 5JVHE 1YJNE 1VQ4E 3CC2E 4IOCE 1Q86G 1VQ6E 2CQLA 1VQOE 5GAEG 3CCSE 5GAHG 3CMEE 3I55E 5DM7E 2OTLE 1Q82G 1M90G 5AN9B 3CCME 1Q7YG 1VQNE 3J7ZG 5GADG 1M1KG 2QA4E 4WFNE 3CCJE 3OW2E 1NJIG 1KD1G 3CMAE 3CCQE 1W2BE 1K9MG 3G4SE 1QVFE 1RL6A 1K8AG 2ZJQE
chains in the Genus database with same CATH superfamily
1VQ9E 1VQME 2PI3O 5B2AO 2G8CO 1VQ8E 1YJWE 3G71E 3CCUE 4IO9E 4IOAE 3PIOE 1FJ1E 2OL6O 3G6EE 3CPWE 1YI2E 2ZJRE 3CCRE 1YIJE 1K73G 2OY8A 1JJ2E 4UY8G 5H1SI 5HL7E 3CD6E 5MLCH 1VQLE 3I56E 1VQ5E 3PIPE 3IGEA 1N8RG 1KC8G 2OL7A 3EC5A 3CF5E 4WFBE 4WFAE 5GAGG 2FKGA 3CCEE 4WCEE 1QVGE 4WF9E 1VQPE 1KQSE 3DLLE 2ZJPE 5DM6E 3CC7E 5B3MO 3CKGA 4U67E 2OTJE 1YITE 1VQKE 5B10O 5JVGE 3IG9A 3CCVE 1VQ7E 1Q81G 2QEXE 3CXCE 1S72E 3CCLE 1YJ9E 3CC4E 1YHQE 5JVHE 2OYBO 1YJNE 1VQ4E 3CC2E 2HKDA 4IOCE 2I5VO 5B11O 1Q86G 1VQ6E 2AF5A 3AUMO 2CQLA 1VQOE 1OSPO 5GAEG 3CCSE 5GAHG 3CMEE 3I55E 2I5ZO 5DM7E 2OTLE 1Q82G 1M90G 5AN9B 3CCME 1Q7YG 1P4PA 1VQNE 1RJLC 3J7ZG 2FKJA 5GADG 2OY7A 2OY5O 1M1KG 3CKFA 2QA4E 2OY1O 4WFNE 3CCJE 3OW2E 1NJIG 1KD1G 3CMAE 3CCQE 1W2BE 1K9MG 3G4SE 1QVFE 1RL6A 1K8AG 2ZJQE 2OL8O
chains in the Genus database with same CATH topology
1VQ9E 1VQME 1VQ8E 1YJWE 3G71E 3CCUE 4IO9E 4IOAE 3PIOE 3G6EE 3CPWE 1YI2E 2ZJRE 3CCRE 1YIJE 1K73G 1JJ2E 4UY8G 5H1SI 5HL7E 3CD6E 5MLCH 1VQLE 3I56E 1VQ5E 3PIPE 1N8RG 1KC8G 3CF5E 4WFBE 4WFAE 5GAGG 3CCEE 4WCEE 1QVGE 4WF9E 1VQPE 1KQSE 3DLLE 2ZJPE 5DM6E 3CC7E 4U67E 2OTJE 1YITE 1VQKE 5JVGE 3CCVE 1VQ7E 1Q81G 2QEXE 3CXCE 1S72E 3CCLE 1YJ9E 3CC4E 1YHQE 5JVHE 1YJNE 1VQ4E 3CC2E 4IOCE 1Q86G 1VQ6E 2CQLA 1VQOE 5GAEG 3CCSE 5GAHG 3CMEE 3I55E 5DM7E 2OTLE 1Q82G 1M90G 5AN9B 3CCME 1Q7YG 1VQNE 3J7ZG 5GADG 1M1KG 2QA4E 4WFNE 3CCJE 3OW2E 1NJIG 1KD1G 3CMAE 3CCQE 1W2BE 1K9MG 3G4SE 1QVFE 1RL6A 1K8AG 2ZJQE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ9 E;  1VQM E;  1VQ8 E;  1YJW E;  3G71 E;  3CCU E;  4IO9 E;  4IOA E;  3PIO E;  3G6E E;  3CPW E;  1YI2 E;  2ZJR E;  3CCR E;  1YIJ E;  1K73 G;  1JJ2 E;  4UY8 G;  5H1S I;  5HL7 E;  3CD6 E;  5MLC H;  1VQL E;  3I56 E;  1VQ5 E;  3PIP E;  1N8R G;  1KC8 G;  3CF5 E;  4WFB E;  4WFA E;  5GAG G;  3CCE E;  4WCE E;  1QVG E;  4WF9 E;  1VQP E;  1KQS E;  3DLL E;  2ZJP E;  5DM6 E;  3CC7 E;  4U67 E;  2OTJ E;  1YIT E;  1VQK E;  5JVG E;  3CCV E;  1VQ7 E;  1Q81 G;  2QEX E;  3CXC E;  1S72 E;  3CCL E;  1YJ9 E;  3CC4 E;  1YHQ E;  5JVH E;  1YJN E;  1VQ4 E;  3CC2 E;  4IOC E;  1Q86 G;  1VQ6 E;  2CQL A;  1VQO E;  5GAE G;  3CCS E;  5GAH G;  3CME E;  3I55 E;  5DM7 E;  2OTL E;  1Q82 G;  1M90 G;  5AN9 B;  3CCM E;  1Q7Y G;  1VQN E;  3J7Z G;  5GAD G;  1M1K G;  2QA4 E;  4WFN E;  3CCJ E;  3OW2 E;  1NJI G;  1KD1 G;  3CMA E;  3CCQ E;  1W2B E;  1K9M G;  3G4S E;  1QVF E;  1RL6 A;  1K8A G;  2ZJQ E; 
#chains in the Genus database with same CATH topology
 1VQ9 E;  1VQM E;  2PI3 O;  5B2A O;  2G8C O;  1VQ8 E;  1YJW E;  3G71 E;  3CCU E;  4IO9 E;  4IOA E;  3PIO E;  1FJ1 E;  2OL6 O;  3G6E E;  3CPW E;  1YI2 E;  2ZJR E;  3CCR E;  1YIJ E;  1K73 G;  2OY8 A;  1JJ2 E;  4UY8 G;  5H1S I;  5HL7 E;  3CD6 E;  5MLC H;  1VQL E;  3I56 E;  1VQ5 E;  3PIP E;  3IGE A;  1N8R G;  1KC8 G;  2OL7 A;  3EC5 A;  3CF5 E;  4WFB E;  4WFA E;  5GAG G;  2FKG A;  3CCE E;  4WCE E;  1QVG E;  4WF9 E;  1VQP E;  1KQS E;  3DLL E;  2ZJP E;  5DM6 E;  3CC7 E;  5B3M O;  3CKG A;  4U67 E;  2OTJ E;  1YIT E;  1VQK E;  5B10 O;  5JVG E;  3IG9 A;  3CCV E;  1VQ7 E;  1Q81 G;  2QEX E;  3CXC E;  1S72 E;  3CCL E;  1YJ9 E;  3CC4 E;  1YHQ E;  5JVH E;  2OYB O;  1YJN E;  1VQ4 E;  3CC2 E;  2HKD A;  4IOC E;  2I5V O;  5B11 O;  1Q86 G;  1VQ6 E;  2AF5 A;  3AUM O;  2CQL A;  1VQO E;  1OSP O;  5GAE G;  3CCS E;  5GAH G;  3CME E;  3I55 E;  2I5Z O;  5DM7 E;  2OTL E;  1Q82 G;  1M90 G;  5AN9 B;  3CCM E;  1Q7Y G;  1P4P A;  1VQN E;  1RJL C;  3J7Z G;  2FKJ A;  5GAD G;  2OY7 A;  2OY5 O;  1M1K G;  3CKF A;  2QA4 E;  2OY1 O;  4WFN E;  3CCJ E;  3OW2 E;  1NJI G;  1KD1 G;  3CMA E;  3CCQ E;  1W2B E;  1K9M G;  3G4S E;  1QVF E;  1RL6 A;  1K8A G;  2ZJQ E;  2OL8 O; 
#chains in the Genus database with same CATH homology
 1VQ9 E;  1VQM E;  1VQ8 E;  1YJW E;  3G71 E;  3CCU E;  4IO9 E;  4IOA E;  3PIO E;  3G6E E;  3CPW E;  1YI2 E;  2ZJR E;  3CCR E;  1YIJ E;  1K73 G;  1JJ2 E;  4UY8 G;  5H1S I;  5HL7 E;  3CD6 E;  5MLC H;  1VQL E;  3I56 E;  1VQ5 E;  3PIP E;  1N8R G;  1KC8 G;  3CF5 E;  4WFB E;  4WFA E;  5GAG G;  3CCE E;  4WCE E;  1QVG E;  4WF9 E;  1VQP E;  1KQS E;  3DLL E;  2ZJP E;  5DM6 E;  3CC7 E;  4U67 E;  2OTJ E;  1YIT E;  1VQK E;  5JVG E;  3CCV E;  1VQ7 E;  1Q81 G;  2QEX E;  3CXC E;  1S72 E;  3CCL E;  1YJ9 E;  3CC4 E;  1YHQ E;  5JVH E;  1YJN E;  1VQ4 E;  3CC2 E;  4IOC E;  1Q86 G;  1VQ6 E;  2CQL A;  1VQO E;  5GAE G;  3CCS E;  5GAH G;  3CME E;  3I55 E;  5DM7 E;  2OTL E;  1Q82 G;  1M90 G;  5AN9 B;  3CCM E;  1Q7Y G;  1VQN E;  3J7Z G;  5GAD G;  1M1K G;  2QA4 E;  4WFN E;  3CCJ E;  3OW2 E;  1NJI G;  1KD1 G;  3CMA E;  3CCQ E;  1W2B E;  1K9M G;  3G4S E;  1QVF E;  1RL6 A;  1K8A G;  2ZJQ E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...