3PIOE

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 25
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pioE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pioE01
3CC4E 3OW2E 3G4SE 5GAHG 3CCRE 2ZJRE 3CCME 5GAEG 1VQ9E 3DLLE 2OTLE 1YJNE 1QVGE 5JVHE 5HL7E 1NJIG 3CF5E 3CXCE 5H1SI 5DM7E 1VQ6E 1K9MG 3PIOE 1N8RG 1KQSE 1YIJE 4WFBE 2QEXE 1YITE 1QVFE 1Q81G 1KC8G 1K73G 5DM6E 1VQ4E 1VQLE 3J7ZG 3CC2E 1M90G 3CMAE 1VQKE 5GADG 4UY8G 3G71E 1VQ7E 3CMEE 5GAGG 1K8AG 3G6EE 3CCLE 2ZJPE 1VQ8E 4U67E 3CCEE 3I56E 3PIPE 1VQ5E 1M1KG 3CCVE 3CD6E 1YJWE 1S72E 3CCUE 1VQPE 1VQNE 2OTJE 2CQLA 4WFAE 1VQOE 1JJ2E 4IOAE 1YI2E 2QA4E 1KD1G 2ZJQE 1VQME 3CCQE 4WFNE 4IO9E 1W2BE 4IOCE 3CCSE 4WCEE 1RL6A 5MLCH 1Q82G 3I55E 1YJ9E 3CPWE 5JVGE 3CC7E 1Q86G 1YHQE 1Q7YG 5AN9B 3CCJE 4WF9E
chains in the Genus database with same CATH superfamily
2FKJA 5B3MO 1FJ1E 3CC4E 3OW2E 3G4SE 5GAHG 3CCRE 2ZJRE 3CCME 2OY7A 5GAEG 1VQ9E 3DLLE 2OL6O 2OTLE 1YJNE 2I5VO 1QVGE 5JVHE 5HL7E 1NJIG 3CF5E 3CXCE 5H1SI 2OY1O 5DM7E 1VQ6E 1K9MG 3PIOE 1N8RG 1KQSE 1YIJE 4WFBE 2I5ZO 2QEXE 2G8CO 1YITE 1QVFE 1Q81G 5DM6E 1K73G 1KC8G 1VQ4E 1VQLE 2OL7A 2AF5A 3J7ZG 3CC2E 1M90G 3CMAE 1VQKE 5GADG 4UY8G 3G71E 1VQ7E 3CMEE 5GAGG 1K8AG 3G6EE 5B11O 3CCLE 2ZJPE 1RJLC 3CKFA 1VQ8E 4U67E 3CCEE 2HKDA 3I56E 3PIPE 1OSPO 1VQ5E 1M1KG 3CCVE 2OY5O 3CD6E 2OYBO 3CKGA 1YJWE 1S72E 5B2AO 3CCUE 3AUMO 1VQPE 1VQNE 2OTJE 2CQLA 4WFAE 1VQOE 1JJ2E 5B10O 4IOAE 1YI2E 2QA4E 1KD1G 1P4PA 2OL8O 2ZJQE 1VQME 2OY8A 3CCQE 4WFNE 4IO9E 1W2BE 4IOCE 2FKGA 3CCSE 4WCEE 1RL6A 5MLCH 1Q82G 2PI3O 3I55E 1YJ9E 3IG9A 3EC5A 3CPWE 3IGEA 5JVGE 3CC7E 1Q86G 1YHQE 1Q7YG 5AN9B 3CCJE 4WF9E
chains in the Genus database with same CATH topology
3CC4E 3OW2E 3G4SE 5GAHG 3CCRE 2ZJRE 3CCME 5GAEG 1VQ9E 3DLLE 2OTLE 1YJNE 1QVGE 5JVHE 5HL7E 1NJIG 3CF5E 3CXCE 5H1SI 5DM7E 1VQ6E 1K9MG 3PIOE 1N8RG 1KQSE 1YIJE 4WFBE 2QEXE 1YITE 1QVFE 1Q81G 1KC8G 1K73G 5DM6E 1VQ4E 1VQLE 3J7ZG 3CC2E 1M90G 3CMAE 1VQKE 5GADG 4UY8G 3G71E 1VQ7E 3CMEE 5GAGG 1K8AG 3G6EE 3CCLE 2ZJPE 1VQ8E 4U67E 3CCEE 3I56E 3PIPE 1VQ5E 1M1KG 3CCVE 3CD6E 1YJWE 1S72E 3CCUE 1VQPE 1VQNE 2OTJE 2CQLA 4WFAE 1VQOE 1JJ2E 4IOAE 1YI2E 2QA4E 1KD1G 2ZJQE 1VQME 3CCQE 4WFNE 4IO9E 1W2BE 4IOCE 3CCSE 4WCEE 1RL6A 5MLCH 1Q82G 3I55E 1YJ9E 3CPWE 5JVGE 3CC7E 1Q86G 1YHQE 1Q7YG 5AN9B 3CCJE 4WF9E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CC4 E;  3OW2 E;  3G4S E;  5GAH G;  3CCR E;  2ZJR E;  3CCM E;  5GAE G;  1VQ9 E;  3DLL E;  2OTL E;  1YJN E;  1QVG E;  5JVH E;  5HL7 E;  1NJI G;  3CF5 E;  3CXC E;  5H1S I;  5DM7 E;  1VQ6 E;  1K9M G;  3PIO E;  1N8R G;  1KQS E;  1YIJ E;  4WFB E;  2QEX E;  1YIT E;  1QVF E;  1Q81 G;  1KC8 G;  1K73 G;  5DM6 E;  1VQ4 E;  1VQL E;  3J7Z G;  3CC2 E;  1M90 G;  3CMA E;  1VQK E;  5GAD G;  4UY8 G;  3G71 E;  1VQ7 E;  3CME E;  5GAG G;  1K8A G;  3G6E E;  3CCL E;  2ZJP E;  1VQ8 E;  4U67 E;  3CCE E;  3I56 E;  3PIP E;  1VQ5 E;  1M1K G;  3CCV E;  3CD6 E;  1YJW E;  1S72 E;  3CCU E;  1VQP E;  1VQN E;  2OTJ E;  2CQL A;  4WFA E;  1VQO E;  1JJ2 E;  4IOA E;  1YI2 E;  2QA4 E;  1KD1 G;  2ZJQ E;  1VQM E;  3CCQ E;  4WFN E;  4IO9 E;  1W2B E;  4IOC E;  3CCS E;  4WCE E;  1RL6 A;  5MLC H;  1Q82 G;  3I55 E;  1YJ9 E;  3CPW E;  5JVG E;  3CC7 E;  1Q86 G;  1YHQ E;  1Q7Y G;  5AN9 B;  3CCJ E;  4WF9 E; 
#chains in the Genus database with same CATH topology
 2FKJ A;  5B3M O;  1FJ1 E;  3CC4 E;  3OW2 E;  3G4S E;  5GAH G;  3CCR E;  2ZJR E;  3CCM E;  2OY7 A;  5GAE G;  1VQ9 E;  3DLL E;  2OL6 O;  2OTL E;  1YJN E;  2I5V O;  1QVG E;  5JVH E;  5HL7 E;  1NJI G;  3CF5 E;  3CXC E;  5H1S I;  2OY1 O;  5DM7 E;  1VQ6 E;  1K9M G;  3PIO E;  1N8R G;  1KQS E;  1YIJ E;  4WFB E;  2I5Z O;  2QEX E;  2G8C O;  1YIT E;  1QVF E;  1Q81 G;  5DM6 E;  1K73 G;  1KC8 G;  1VQ4 E;  1VQL E;  2OL7 A;  2AF5 A;  3J7Z G;  3CC2 E;  1M90 G;  3CMA E;  1VQK E;  5GAD G;  4UY8 G;  3G71 E;  1VQ7 E;  3CME E;  5GAG G;  1K8A G;  3G6E E;  5B11 O;  3CCL E;  2ZJP E;  1RJL C;  3CKF A;  1VQ8 E;  4U67 E;  3CCE E;  2HKD A;  3I56 E;  3PIP E;  1OSP O;  1VQ5 E;  1M1K G;  3CCV E;  2OY5 O;  3CD6 E;  2OYB O;  3CKG A;  1YJW E;  1S72 E;  5B2A O;  3CCU E;  3AUM O;  1VQP E;  1VQN E;  2OTJ E;  2CQL A;  4WFA E;  1VQO E;  1JJ2 E;  5B10 O;  4IOA E;  1YI2 E;  2QA4 E;  1KD1 G;  1P4P A;  2OL8 O;  2ZJQ E;  1VQM E;  2OY8 A;  3CCQ E;  4WFN E;  4IO9 E;  1W2B E;  4IOC E;  2FKG A;  3CCS E;  4WCE E;  1RL6 A;  5MLC H;  1Q82 G;  2PI3 O;  3I55 E;  1YJ9 E;  3IG9 A;  3EC5 A;  3CPW E;  3IGE A;  5JVG E;  3CC7 E;  1Q86 G;  1YHQ E;  1Q7Y G;  5AN9 B;  3CCJ E;  4WF9 E; 
#chains in the Genus database with same CATH homology
 3CC4 E;  3OW2 E;  3G4S E;  5GAH G;  3CCR E;  2ZJR E;  3CCM E;  5GAE G;  1VQ9 E;  3DLL E;  2OTL E;  1YJN E;  1QVG E;  5JVH E;  5HL7 E;  1NJI G;  3CF5 E;  3CXC E;  5H1S I;  5DM7 E;  1VQ6 E;  1K9M G;  3PIO E;  1N8R G;  1KQS E;  1YIJ E;  4WFB E;  2QEX E;  1YIT E;  1QVF E;  1Q81 G;  1KC8 G;  1K73 G;  5DM6 E;  1VQ4 E;  1VQL E;  3J7Z G;  3CC2 E;  1M90 G;  3CMA E;  1VQK E;  5GAD G;  4UY8 G;  3G71 E;  1VQ7 E;  3CME E;  5GAG G;  1K8A G;  3G6E E;  3CCL E;  2ZJP E;  1VQ8 E;  4U67 E;  3CCE E;  3I56 E;  3PIP E;  1VQ5 E;  1M1K G;  3CCV E;  3CD6 E;  1YJW E;  1S72 E;  3CCU E;  1VQP E;  1VQN E;  2OTJ E;  2CQL A;  4WFA E;  1VQO E;  1JJ2 E;  4IOA E;  1YI2 E;  2QA4 E;  1KD1 G;  2ZJQ E;  1VQM E;  3CCQ E;  4WFN E;  4IO9 E;  1W2B E;  4IOC E;  3CCS E;  4WCE E;  1RL6 A;  5MLC H;  1Q82 G;  3I55 E;  1YJ9 E;  3CPW E;  5JVG E;  3CC7 E;  1Q86 G;  1YHQ E;  1Q7Y G;  5AN9 B;  3CCJ E;  4WF9 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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