3PIPE

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 23
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pipE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3pipE01
3I55E 3CCQE 1YJWE 4WF9E 3CCUE 2CQLA 1YHQE 4IOCE 4U67E 2QA4E 1VQKE 3I56E 5HL7E 3CMEE 1N8RG 2OTJE 3G4SE 1S72E 1YI2E 1KQSE 3PIPE 5GAEG 4WCEE 1QVGE 3CCLE 1JJ2E 1Q7YG 3OW2E 2ZJRE 2QEXE 1Q82G 2ZJQE 1VQ9E 1VQ8E 1Q81G 3G71E 1VQ6E 1K73G 3DLLE 1VQLE 1M1KG 3CMAE 1YJNE 1K9MG 1Q86G 1VQ7E 3CCME 1M90G 4WFNE 3PIOE 3CXCE 5AN9B 3CD6E 4IOAE 1VQME 4WFAE 5DM7E 1VQOE 3CCVE 5H1SI 5DM6E 3CC7E 1W2BE 3J7ZG 3CCSE 1VQ5E 5GAHG 1VQPE 1VQNE 3CF5E 5JVGE 1NJIG 1YITE 2OTLE 4UY8G 4WFBE 3CC2E 1YJ9E 1YIJE 3CCJE 1VQ4E 3G6EE 1KD1G 5MLCH 3CC4E 5JVHE 1KC8G 5GAGG 1QVFE 5GADG 2ZJPE 3CCEE 1RL6A 1K8AG 3CPWE 4IO9E 3CCRE
chains in the Genus database with same CATH superfamily
3I55E 3CCQE 1YJWE 4WF9E 2OY8A 3CCUE 2CQLA 1YHQE 4IOCE 2FKJA 1FJ1E 4U67E 2QA4E 1VQKE 3I56E 5HL7E 3CMEE 1N8RG 2OTJE 3AUMO 3G4SE 1S72E 1YI2E 1KQSE 2OL6O 3PIPE 5B10O 5GAEG 4WCEE 3IG9A 1QVGE 2OY1O 3CCLE 1JJ2E 1Q7YG 3OW2E 2ZJRE 2QEXE 1Q82G 3CKFA 2ZJQE 1VQ9E 1VQ8E 1Q81G 5B2AO 2OY7A 3G71E 1VQ6E 1K73G 3DLLE 1VQLE 5B3MO 1M1KG 3CMAE 1YJNE 1K9MG 1Q86G 1VQ7E 2OL8O 3CCME 2OY5O 1M90G 4WFNE 2PI3O 2OL7A 2FKGA 2OYBO 3PIOE 3CXCE 5AN9B 3CD6E 4IOAE 5B11O 1VQME 4WFAE 5DM7E 1VQOE 1RJLC 3CCVE 5H1SI 5DM6E 3CC7E 1W2BE 3J7ZG 3CCSE 3IGEA 1VQ5E 5GAHG 1VQPE 1VQNE 3CF5E 5JVGE 3CKGA 1NJIG 1YITE 2I5VO 2OTLE 4UY8G 4WFBE 3CC2E 2I5ZO 1YJ9E 1YIJE 1OSPO 2HKDA 3CCJE 2AF5A 1VQ4E 3G6EE 1KD1G 1P4PA 5MLCH 3CC4E 5JVHE 1KC8G 5GAGG 1QVFE 5GADG 2ZJPE 3CCEE 1RL6A 1K8AG 2G8CO 3EC5A 3CPWE 4IO9E 3CCRE
chains in the Genus database with same CATH topology
3I55E 3CCQE 1YJWE 4WF9E 3CCUE 2CQLA 1YHQE 4IOCE 4U67E 2QA4E 1VQKE 3I56E 5HL7E 3CMEE 1N8RG 2OTJE 3G4SE 1S72E 1YI2E 1KQSE 3PIPE 5GAEG 4WCEE 1QVGE 3CCLE 1JJ2E 1Q7YG 3OW2E 2ZJRE 2QEXE 1Q82G 2ZJQE 1VQ9E 1VQ8E 1Q81G 3G71E 1VQ6E 1K73G 3DLLE 1VQLE 1M1KG 3CMAE 1YJNE 1K9MG 1Q86G 1VQ7E 3CCME 1M90G 4WFNE 3PIOE 3CXCE 5AN9B 3CD6E 4IOAE 1VQME 4WFAE 5DM7E 1VQOE 3CCVE 5H1SI 5DM6E 3CC7E 1W2BE 3J7ZG 3CCSE 1VQ5E 5GAHG 1VQPE 1VQNE 3CF5E 5JVGE 1NJIG 1YITE 2OTLE 4UY8G 4WFBE 3CC2E 1YJ9E 1YIJE 3CCJE 1VQ4E 3G6EE 1KD1G 5MLCH 3CC4E 5JVHE 1KC8G 5GAGG 1QVFE 5GADG 2ZJPE 3CCEE 1RL6A 1K8AG 3CPWE 4IO9E 3CCRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I55 E;  3CCQ E;  1YJW E;  4WF9 E;  3CCU E;  2CQL A;  1YHQ E;  4IOC E;  4U67 E;  2QA4 E;  1VQK E;  3I56 E;  5HL7 E;  3CME E;  1N8R G;  2OTJ E;  3G4S E;  1S72 E;  1YI2 E;  1KQS E;  3PIP E;  5GAE G;  4WCE E;  1QVG E;  3CCL E;  1JJ2 E;  1Q7Y G;  3OW2 E;  2ZJR E;  2QEX E;  1Q82 G;  2ZJQ E;  1VQ9 E;  1VQ8 E;  1Q81 G;  3G71 E;  1VQ6 E;  1K73 G;  3DLL E;  1VQL E;  1M1K G;  3CMA E;  1YJN E;  1K9M G;  1Q86 G;  1VQ7 E;  3CCM E;  1M90 G;  4WFN E;  3PIO E;  3CXC E;  5AN9 B;  3CD6 E;  4IOA E;  1VQM E;  4WFA E;  5DM7 E;  1VQO E;  3CCV E;  5H1S I;  5DM6 E;  3CC7 E;  1W2B E;  3J7Z G;  3CCS E;  1VQ5 E;  5GAH G;  1VQP E;  1VQN E;  3CF5 E;  5JVG E;  1NJI G;  1YIT E;  2OTL E;  4UY8 G;  4WFB E;  3CC2 E;  1YJ9 E;  1YIJ E;  3CCJ E;  1VQ4 E;  3G6E E;  1KD1 G;  5MLC H;  3CC4 E;  5JVH E;  1KC8 G;  5GAG G;  1QVF E;  5GAD G;  2ZJP E;  3CCE E;  1RL6 A;  1K8A G;  3CPW E;  4IO9 E;  3CCR E; 
#chains in the Genus database with same CATH topology
 3I55 E;  3CCQ E;  1YJW E;  4WF9 E;  2OY8 A;  3CCU E;  2CQL A;  1YHQ E;  4IOC E;  2FKJ A;  1FJ1 E;  4U67 E;  2QA4 E;  1VQK E;  3I56 E;  5HL7 E;  3CME E;  1N8R G;  2OTJ E;  3AUM O;  3G4S E;  1S72 E;  1YI2 E;  1KQS E;  2OL6 O;  3PIP E;  5B10 O;  5GAE G;  4WCE E;  3IG9 A;  1QVG E;  2OY1 O;  3CCL E;  1JJ2 E;  1Q7Y G;  3OW2 E;  2ZJR E;  2QEX E;  1Q82 G;  3CKF A;  2ZJQ E;  1VQ9 E;  1VQ8 E;  1Q81 G;  5B2A O;  2OY7 A;  3G71 E;  1VQ6 E;  1K73 G;  3DLL E;  1VQL E;  5B3M O;  1M1K G;  3CMA E;  1YJN E;  1K9M G;  1Q86 G;  1VQ7 E;  2OL8 O;  3CCM E;  2OY5 O;  1M90 G;  4WFN E;  2PI3 O;  2OL7 A;  2FKG A;  2OYB O;  3PIO E;  3CXC E;  5AN9 B;  3CD6 E;  4IOA E;  5B11 O;  1VQM E;  4WFA E;  5DM7 E;  1VQO E;  1RJL C;  3CCV E;  5H1S I;  5DM6 E;  3CC7 E;  1W2B E;  3J7Z G;  3CCS E;  3IGE A;  1VQ5 E;  5GAH G;  1VQP E;  1VQN E;  3CF5 E;  5JVG E;  3CKG A;  1NJI G;  1YIT E;  2I5V O;  2OTL E;  4UY8 G;  4WFB E;  3CC2 E;  2I5Z O;  1YJ9 E;  1YIJ E;  1OSP O;  2HKD A;  3CCJ E;  2AF5 A;  1VQ4 E;  3G6E E;  1KD1 G;  1P4P A;  5MLC H;  3CC4 E;  5JVH E;  1KC8 G;  5GAG G;  1QVF E;  5GAD G;  2ZJP E;  3CCE E;  1RL6 A;  1K8A G;  2G8C O;  3EC5 A;  3CPW E;  4IO9 E;  3CCR E; 
#chains in the Genus database with same CATH homology
 3I55 E;  3CCQ E;  1YJW E;  4WF9 E;  3CCU E;  2CQL A;  1YHQ E;  4IOC E;  4U67 E;  2QA4 E;  1VQK E;  3I56 E;  5HL7 E;  3CME E;  1N8R G;  2OTJ E;  3G4S E;  1S72 E;  1YI2 E;  1KQS E;  3PIP E;  5GAE G;  4WCE E;  1QVG E;  3CCL E;  1JJ2 E;  1Q7Y G;  3OW2 E;  2ZJR E;  2QEX E;  1Q82 G;  2ZJQ E;  1VQ9 E;  1VQ8 E;  1Q81 G;  3G71 E;  1VQ6 E;  1K73 G;  3DLL E;  1VQL E;  1M1K G;  3CMA E;  1YJN E;  1K9M G;  1Q86 G;  1VQ7 E;  3CCM E;  1M90 G;  4WFN E;  3PIO E;  3CXC E;  5AN9 B;  3CD6 E;  4IOA E;  1VQM E;  4WFA E;  5DM7 E;  1VQO E;  3CCV E;  5H1S I;  5DM6 E;  3CC7 E;  1W2B E;  3J7Z G;  3CCS E;  1VQ5 E;  5GAH G;  1VQP E;  1VQN E;  3CF5 E;  5JVG E;  1NJI G;  1YIT E;  2OTL E;  4UY8 G;  4WFB E;  3CC2 E;  1YJ9 E;  1YIJ E;  3CCJ E;  1VQ4 E;  3G6E E;  1KD1 G;  5MLC H;  3CC4 E;  5JVH E;  1KC8 G;  5GAG G;  1QVF E;  5GAD G;  2ZJP E;  3CCE E;  1RL6 A;  1K8A G;  3CPW E;  4IO9 E;  3CCR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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