4IO9E

Crystal structure of compound 4d bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome/ribosome inhibitor
publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule keywords 23S ribosomal RNA
total genus 28
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4io9E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4io9E01
1VQ7E 3CC4E 1VQ6E 3CC7E 5DM7E 3CCQE 2ZJQE 4WFAE 1YJNE 2ZJPE 3CMEE 3PIOE 3CCSE 3CCVE 3J7ZG 1VQNE 3CMAE 3CCJE 1YI2E 5GADG 3OW2E 2OTLE 5HL7E 3G71E 1JJ2E 1YIJE 2ZJRE 5GAGG 4WFNE 2OTJE 3CCME 1VQME 1KQSE 1N8RG 4UY8G 3CF5E 3I55E 1Q82G 4IOAE 2CQLA 5JVHE 5MLCH 5GAEG 5AN9B 1NJIG 1VQ4E 1YJ9E 1Q81G 3CD6E 1VQ9E 1YJWE 4IO9E 5H1SI 1KD1G 1K8AG 1M90G 1K73G 4U67E 1QVFE 1Q86G 1S72E 1Q7YG 1M1KG 3CCLE 1VQOE 3CPWE 3CCRE 1W2BE 2QEXE 1VQ8E 1K9MG 3CC2E 1VQLE 2QA4E 4WCEE 1QVGE 5JVGE 1YHQE 5DM6E 1VQ5E 3DLLE 3CXCE 3G6EE 1VQKE 1KC8G 3PIPE 4IOCE 3CCEE 1YITE 5GAHG 3G4SE 1RL6A 1VQPE 4WF9E 3I56E 3CCUE 4WFBE
chains in the Genus database with same CATH superfamily
1VQ7E 3CC4E 1VQ6E 3CC7E 5DM7E 3CCQE 2ZJQE 4WFAE 2HKDA 1YJNE 2ZJPE 3CMEE 3CCSE 3IG9A 3PIOE 3CCVE 3J7ZG 1VQNE 3CMAE 3CCJE 5B2AO 1YI2E 5GADG 3OW2E 5B3MO 2OTLE 5HL7E 3G71E 1JJ2E 1YIJE 2ZJRE 5GAGG 4WFNE 2OTJE 3CCME 2OY7A 1VQME 1KQSE 1N8RG 3AUMO 4UY8G 3CF5E 3I55E 1Q82G 4IOAE 2OY1O 2CQLA 2FKJA 5JVHE 2PI3O 5MLCH 5GAEG 2OL7A 2I5ZO 5AN9B 1NJIG 2OYBO 1VQ4E 2FKGA 3CKFA 1YJ9E 3EC5A 2OL8O 1Q81G 3CD6E 1VQ9E 1YJWE 4IO9E 5H1SI 2AF5A 1KD1G 1K8AG 1M90G 2I5VO 1K73G 4U67E 1QVFE 1Q86G 1S72E 1Q7YG 1M1KG 3CCLE 1OSPO 1VQOE 3CPWE 3CCRE 1W2BE 2QEXE 1VQ8E 1K9MG 3CC2E 1VQLE 2QA4E 4WCEE 1QVGE 5JVGE 1YHQE 5DM6E 5B10O 1VQ5E 3DLLE 2OY8A 3CXCE 1FJ1E 3G6EE 1VQKE 1KC8G 3PIPE 4IOCE 3CCEE 1YITE 5GAHG 3G4SE 2OY5O 1RL6A 2G8CO 1RJLC 1VQPE 4WF9E 3IGEA 5B11O 3I56E 3CKGA 1P4PA 3CCUE 4WFBE 2OL6O
chains in the Genus database with same CATH topology
1VQ7E 3CC4E 1VQ6E 3CC7E 5DM7E 3CCQE 2ZJQE 4WFAE 1YJNE 2ZJPE 3CMEE 3PIOE 3CCSE 3CCVE 3J7ZG 1VQNE 3CMAE 3CCJE 1YI2E 5GADG 3OW2E 2OTLE 5HL7E 3G71E 1JJ2E 1YIJE 2ZJRE 5GAGG 4WFNE 2OTJE 3CCME 1VQME 1KQSE 1N8RG 4UY8G 3CF5E 3I55E 1Q82G 4IOAE 2CQLA 5JVHE 5MLCH 5GAEG 5AN9B 1NJIG 1VQ4E 1YJ9E 1Q81G 3CD6E 1VQ9E 1YJWE 4IO9E 5H1SI 1KD1G 1K8AG 1M90G 1K73G 4U67E 1QVFE 1Q86G 1S72E 1Q7YG 1M1KG 3CCLE 1VQOE 3CPWE 3CCRE 1W2BE 2QEXE 1VQ8E 1K9MG 3CC2E 1VQLE 2QA4E 4WCEE 1QVGE 5JVGE 1YHQE 5DM6E 1VQ5E 3DLLE 3CXCE 3G6EE 1VQKE 1KC8G 3PIPE 4IOCE 3CCEE 1YITE 5GAHG 3G4SE 1RL6A 1VQPE 4WF9E 3I56E 3CCUE 4WFBE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ7 E;  3CC4 E;  1VQ6 E;  3CC7 E;  5DM7 E;  3CCQ E;  2ZJQ E;  4WFA E;  1YJN E;  2ZJP E;  3CME E;  3PIO E;  3CCS E;  3CCV E;  3J7Z G;  1VQN E;  3CMA E;  3CCJ E;  1YI2 E;  5GAD G;  3OW2 E;  2OTL E;  5HL7 E;  3G71 E;  1JJ2 E;  1YIJ E;  2ZJR E;  5GAG G;  4WFN E;  2OTJ E;  3CCM E;  1VQM E;  1KQS E;  1N8R G;  4UY8 G;  3CF5 E;  3I55 E;  1Q82 G;  4IOA E;  2CQL A;  5JVH E;  5MLC H;  5GAE G;  5AN9 B;  1NJI G;  1VQ4 E;  1YJ9 E;  1Q81 G;  3CD6 E;  1VQ9 E;  1YJW E;  4IO9 E;  5H1S I;  1KD1 G;  1K8A G;  1M90 G;  1K73 G;  4U67 E;  1QVF E;  1Q86 G;  1S72 E;  1Q7Y G;  1M1K G;  3CCL E;  1VQO E;  3CPW E;  3CCR E;  1W2B E;  2QEX E;  1VQ8 E;  1K9M G;  3CC2 E;  1VQL E;  2QA4 E;  4WCE E;  1QVG E;  5JVG E;  1YHQ E;  5DM6 E;  1VQ5 E;  3DLL E;  3CXC E;  3G6E E;  1VQK E;  1KC8 G;  3PIP E;  4IOC E;  3CCE E;  1YIT E;  5GAH G;  3G4S E;  1RL6 A;  1VQP E;  4WF9 E;  3I56 E;  3CCU E;  4WFB E; 
#chains in the Genus database with same CATH topology
 1VQ7 E;  3CC4 E;  1VQ6 E;  3CC7 E;  5DM7 E;  3CCQ E;  2ZJQ E;  4WFA E;  2HKD A;  1YJN E;  2ZJP E;  3CME E;  3CCS E;  3IG9 A;  3PIO E;  3CCV E;  3J7Z G;  1VQN E;  3CMA E;  3CCJ E;  5B2A O;  1YI2 E;  5GAD G;  3OW2 E;  5B3M O;  2OTL E;  5HL7 E;  3G71 E;  1JJ2 E;  1YIJ E;  2ZJR E;  5GAG G;  4WFN E;  2OTJ E;  3CCM E;  2OY7 A;  1VQM E;  1KQS E;  1N8R G;  3AUM O;  4UY8 G;  3CF5 E;  3I55 E;  1Q82 G;  4IOA E;  2OY1 O;  2CQL A;  2FKJ A;  5JVH E;  2PI3 O;  5MLC H;  5GAE G;  2OL7 A;  2I5Z O;  5AN9 B;  1NJI G;  2OYB O;  1VQ4 E;  2FKG A;  3CKF A;  1YJ9 E;  3EC5 A;  2OL8 O;  1Q81 G;  3CD6 E;  1VQ9 E;  1YJW E;  4IO9 E;  5H1S I;  2AF5 A;  1KD1 G;  1K8A G;  1M90 G;  2I5V O;  1K73 G;  4U67 E;  1QVF E;  1Q86 G;  1S72 E;  1Q7Y G;  1M1K G;  3CCL E;  1OSP O;  1VQO E;  3CPW E;  3CCR E;  1W2B E;  2QEX E;  1VQ8 E;  1K9M G;  3CC2 E;  1VQL E;  2QA4 E;  4WCE E;  1QVG E;  5JVG E;  1YHQ E;  5DM6 E;  5B10 O;  1VQ5 E;  3DLL E;  2OY8 A;  3CXC E;  1FJ1 E;  3G6E E;  1VQK E;  1KC8 G;  3PIP E;  4IOC E;  3CCE E;  1YIT E;  5GAH G;  3G4S E;  2OY5 O;  1RL6 A;  2G8C O;  1RJL C;  1VQP E;  4WF9 E;  3IGE A;  5B11 O;  3I56 E;  3CKG A;  1P4P A;  3CCU E;  4WFB E;  2OL6 O; 
#chains in the Genus database with same CATH homology
 1VQ7 E;  3CC4 E;  1VQ6 E;  3CC7 E;  5DM7 E;  3CCQ E;  2ZJQ E;  4WFA E;  1YJN E;  2ZJP E;  3CME E;  3PIO E;  3CCS E;  3CCV E;  3J7Z G;  1VQN E;  3CMA E;  3CCJ E;  1YI2 E;  5GAD G;  3OW2 E;  2OTL E;  5HL7 E;  3G71 E;  1JJ2 E;  1YIJ E;  2ZJR E;  5GAG G;  4WFN E;  2OTJ E;  3CCM E;  1VQM E;  1KQS E;  1N8R G;  4UY8 G;  3CF5 E;  3I55 E;  1Q82 G;  4IOA E;  2CQL A;  5JVH E;  5MLC H;  5GAE G;  5AN9 B;  1NJI G;  1VQ4 E;  1YJ9 E;  1Q81 G;  3CD6 E;  1VQ9 E;  1YJW E;  4IO9 E;  5H1S I;  1KD1 G;  1K8A G;  1M90 G;  1K73 G;  4U67 E;  1QVF E;  1Q86 G;  1S72 E;  1Q7Y G;  1M1K G;  3CCL E;  1VQO E;  3CPW E;  3CCR E;  1W2B E;  2QEX E;  1VQ8 E;  1K9M G;  3CC2 E;  1VQL E;  2QA4 E;  4WCE E;  1QVG E;  5JVG E;  1YHQ E;  5DM6 E;  1VQ5 E;  3DLL E;  3CXC E;  3G6E E;  1VQK E;  1KC8 G;  3PIP E;  4IOC E;  3CCE E;  1YIT E;  5GAH G;  3G4S E;  1RL6 A;  1VQP E;  4WF9 E;  3I56 E;  3CCU E;  4WFB E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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