4IOAE

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4ioaE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4ioaE01
2CQLA 1JJ2E 1QVFE 4UY8G 4WFAE 3G6EE 3G71E 3OW2E 1VQ9E 3CCSE 4WFBE 5GAHG 3G4SE 1YHQE 5HL7E 1KD1G 5GAGG 2QEXE 1KQSE 3CCME 1K73G 1VQOE 1VQME 3CD6E 1K9MG 1N8RG 3CPWE 1Q81G 1Q7YG 1YIJE 2OTJE 1S72E 1YITE 1KC8G 4WCEE 5H1SI 1Q82G 3CCJE 3CCLE 4WFNE 5GAEG 5JVGE 1VQLE 1NJIG 1QVGE 4IOCE 3PIOE 1YJWE 2ZJQE 3CC7E 3I56E 3CMAE 2ZJRE 1YI2E 3CCUE 3CF5E 4WF9E 3CMEE 5GADG 3CXCE 3CCRE 1VQNE 1RL6A 1YJNE 1VQ7E 3CC2E 2QA4E 1VQ5E 3DLLE 2ZJPE 1YJ9E 1VQ6E 3PIPE 5DM6E 3CCVE 5DM7E 1Q86G 4IO9E 1VQ4E 3CCQE 5MLCH 3CCEE 1VQ8E 4IOAE 1M1KG 1W2BE 1VQPE 1M90G 4U67E 2OTLE 3I55E 3J7ZG 5AN9B 1VQKE 5JVHE 1K8AG 3CC4E
chains in the Genus database with same CATH superfamily
2CQLA 1JJ2E 1QVFE 4UY8G 4WFAE 3IG9A 3G6EE 3G71E 3OW2E 1VQ9E 3CCSE 4WFBE 5GAHG 3G4SE 3CKFA 1YHQE 5HL7E 1KD1G 5GAGG 2FKJA 2QEXE 5B3MO 3AUMO 2OL7A 1KQSE 3CCME 1FJ1E 3EC5A 1K73G 1VQOE 1VQME 3CD6E 2FKGA 1K9MG 1N8RG 3CPWE 1P4PA 2OL6O 1Q81G 1Q7YG 5B10O 1YIJE 2OTJE 1S72E 1YITE 1KC8G 2OY8A 4WCEE 5H1SI 1Q82G 2AF5A 3CCJE 3CCLE 4WFNE 5GAEG 5JVGE 1VQLE 1NJIG 1QVGE 3IGEA 4IOCE 3PIOE 1YJWE 2ZJQE 2OY7A 3CC7E 3I56E 2OY5O 3CMAE 2ZJRE 1YI2E 2I5ZO 3CCUE 3CF5E 4WF9E 3CKGA 3CMEE 5GADG 3CXCE 3CCRE 1VQNE 1RL6A 1YJNE 2PI3O 1VQ7E 3CC2E 2QA4E 1VQ5E 3DLLE 2ZJPE 1YJ9E 1VQ6E 2OL8O 3PIPE 5B2AO 5B11O 5DM6E 2OYBO 3CCVE 5DM7E 1Q86G 2I5VO 4IO9E 1VQ4E 3CCQE 5MLCH 1OSPO 3CCEE 1VQ8E 2OY1O 4IOAE 1M1KG 1W2BE 2G8CO 2HKDA 1RJLC 1VQPE 1M90G 4U67E 2OTLE 3I55E 3J7ZG 5AN9B 1VQKE 5JVHE 1K8AG 3CC4E
chains in the Genus database with same CATH topology
2CQLA 1JJ2E 1QVFE 4UY8G 4WFAE 3G6EE 3G71E 3OW2E 1VQ9E 3CCSE 4WFBE 5GAHG 3G4SE 1YHQE 5HL7E 1KD1G 5GAGG 2QEXE 1KQSE 3CCME 1K73G 1VQOE 1VQME 3CD6E 1K9MG 1N8RG 3CPWE 1Q81G 1Q7YG 1YIJE 2OTJE 1S72E 1YITE 1KC8G 4WCEE 5H1SI 1Q82G 3CCJE 3CCLE 4WFNE 5GAEG 5JVGE 1VQLE 1NJIG 1QVGE 4IOCE 3PIOE 1YJWE 2ZJQE 3CC7E 3I56E 3CMAE 2ZJRE 1YI2E 3CCUE 3CF5E 4WF9E 3CMEE 5GADG 3CXCE 3CCRE 1VQNE 1RL6A 1YJNE 1VQ7E 3CC2E 2QA4E 1VQ5E 3DLLE 2ZJPE 1YJ9E 1VQ6E 3PIPE 5DM6E 3CCVE 5DM7E 1Q86G 4IO9E 1VQ4E 3CCQE 5MLCH 3CCEE 1VQ8E 4IOAE 1M1KG 1W2BE 1VQPE 1M90G 4U67E 2OTLE 3I55E 3J7ZG 5AN9B 1VQKE 5JVHE 1K8AG 3CC4E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CQL A;  1JJ2 E;  1QVF E;  4UY8 G;  4WFA E;  3G6E E;  3G71 E;  3OW2 E;  1VQ9 E;  3CCS E;  4WFB E;  5GAH G;  3G4S E;  1YHQ E;  5HL7 E;  1KD1 G;  5GAG G;  2QEX E;  1KQS E;  3CCM E;  1K73 G;  1VQO E;  1VQM E;  3CD6 E;  1K9M G;  1N8R G;  3CPW E;  1Q81 G;  1Q7Y G;  1YIJ E;  2OTJ E;  1S72 E;  1YIT E;  1KC8 G;  4WCE E;  5H1S I;  1Q82 G;  3CCJ E;  3CCL E;  4WFN E;  5GAE G;  5JVG E;  1VQL E;  1NJI G;  1QVG E;  4IOC E;  3PIO E;  1YJW E;  2ZJQ E;  3CC7 E;  3I56 E;  3CMA E;  2ZJR E;  1YI2 E;  3CCU E;  3CF5 E;  4WF9 E;  3CME E;  5GAD G;  3CXC E;  3CCR E;  1VQN E;  1RL6 A;  1YJN E;  1VQ7 E;  3CC2 E;  2QA4 E;  1VQ5 E;  3DLL E;  2ZJP E;  1YJ9 E;  1VQ6 E;  3PIP E;  5DM6 E;  3CCV E;  5DM7 E;  1Q86 G;  4IO9 E;  1VQ4 E;  3CCQ E;  5MLC H;  3CCE E;  1VQ8 E;  4IOA E;  1M1K G;  1W2B E;  1VQP E;  1M90 G;  4U67 E;  2OTL E;  3I55 E;  3J7Z G;  5AN9 B;  1VQK E;  5JVH E;  1K8A G;  3CC4 E; 
#chains in the Genus database with same CATH topology
 2CQL A;  1JJ2 E;  1QVF E;  4UY8 G;  4WFA E;  3IG9 A;  3G6E E;  3G71 E;  3OW2 E;  1VQ9 E;  3CCS E;  4WFB E;  5GAH G;  3G4S E;  3CKF A;  1YHQ E;  5HL7 E;  1KD1 G;  5GAG G;  2FKJ A;  2QEX E;  5B3M O;  3AUM O;  2OL7 A;  1KQS E;  3CCM E;  1FJ1 E;  3EC5 A;  1K73 G;  1VQO E;  1VQM E;  3CD6 E;  2FKG A;  1K9M G;  1N8R G;  3CPW E;  1P4P A;  2OL6 O;  1Q81 G;  1Q7Y G;  5B10 O;  1YIJ E;  2OTJ E;  1S72 E;  1YIT E;  1KC8 G;  2OY8 A;  4WCE E;  5H1S I;  1Q82 G;  2AF5 A;  3CCJ E;  3CCL E;  4WFN E;  5GAE G;  5JVG E;  1VQL E;  1NJI G;  1QVG E;  3IGE A;  4IOC E;  3PIO E;  1YJW E;  2ZJQ E;  2OY7 A;  3CC7 E;  3I56 E;  2OY5 O;  3CMA E;  2ZJR E;  1YI2 E;  2I5Z O;  3CCU E;  3CF5 E;  4WF9 E;  3CKG A;  3CME E;  5GAD G;  3CXC E;  3CCR E;  1VQN E;  1RL6 A;  1YJN E;  2PI3 O;  1VQ7 E;  3CC2 E;  2QA4 E;  1VQ5 E;  3DLL E;  2ZJP E;  1YJ9 E;  1VQ6 E;  2OL8 O;  3PIP E;  5B2A O;  5B11 O;  5DM6 E;  2OYB O;  3CCV E;  5DM7 E;  1Q86 G;  2I5V O;  4IO9 E;  1VQ4 E;  3CCQ E;  5MLC H;  1OSP O;  3CCE E;  1VQ8 E;  2OY1 O;  4IOA E;  1M1K G;  1W2B E;  2G8C O;  2HKD A;  1RJL C;  1VQP E;  1M90 G;  4U67 E;  2OTL E;  3I55 E;  3J7Z G;  5AN9 B;  1VQK E;  5JVH E;  1K8A G;  3CC4 E; 
#chains in the Genus database with same CATH homology
 2CQL A;  1JJ2 E;  1QVF E;  4UY8 G;  4WFA E;  3G6E E;  3G71 E;  3OW2 E;  1VQ9 E;  3CCS E;  4WFB E;  5GAH G;  3G4S E;  1YHQ E;  5HL7 E;  1KD1 G;  5GAG G;  2QEX E;  1KQS E;  3CCM E;  1K73 G;  1VQO E;  1VQM E;  3CD6 E;  1K9M G;  1N8R G;  3CPW E;  1Q81 G;  1Q7Y G;  1YIJ E;  2OTJ E;  1S72 E;  1YIT E;  1KC8 G;  4WCE E;  5H1S I;  1Q82 G;  3CCJ E;  3CCL E;  4WFN E;  5GAE G;  5JVG E;  1VQL E;  1NJI G;  1QVG E;  4IOC E;  3PIO E;  1YJW E;  2ZJQ E;  3CC7 E;  3I56 E;  3CMA E;  2ZJR E;  1YI2 E;  3CCU E;  3CF5 E;  4WF9 E;  3CME E;  5GAD G;  3CXC E;  3CCR E;  1VQN E;  1RL6 A;  1YJN E;  1VQ7 E;  3CC2 E;  2QA4 E;  1VQ5 E;  3DLL E;  2ZJP E;  1YJ9 E;  1VQ6 E;  3PIP E;  5DM6 E;  3CCV E;  5DM7 E;  1Q86 G;  4IO9 E;  1VQ4 E;  3CCQ E;  5MLC H;  3CCE E;  1VQ8 E;  4IOA E;  1M1K G;  1W2B E;  1VQP E;  1M90 G;  4U67 E;  2OTL E;  3I55 E;  3J7Z G;  5AN9 B;  1VQK E;  5JVH E;  1K8A G;  3CC4 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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