4IOAE

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4ioaE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4ioaE01
1KC8G 1VQNE 3CC2E 4WFNE 5JVGE 3I56E 1W2BE 1RL6A 1QVFE 1YJ9E 1VQ5E 5DM7E 3CCJE 3OW2E 1JJ2E 1VQ6E 1QVGE 1YHQE 1Q82G 1Q81G 3CPWE 4U67E 3CC7E 2QEXE 3G4SE 2OTJE 1VQME 3CD6E 1VQ4E 5HL7E 3PIPE 5DM6E 3CMAE 5GADG 1Q7YG 3G6EE 5GAHG 3CCVE 3CCRE 1K73G 3CXCE 1YJNE 4UY8G 3CCLE 5GAGG 5MLCH 5GAEG 3CCQE 1M1KG 3CCME 4IOAE 1YIJE 4IO9E 2ZJPE 5AN9B 1YJWE 4IOCE 1VQKE 2QA4E 5H1SI 3I55E 1YI2E 3DLLE 1NJIG 1M90G 4WF9E 1K8AG 3CC4E 3CF5E 1VQOE 4WFAE 1VQLE 1VQ9E 3CCEE 1KQSE 1YITE 5JVHE 2ZJRE 3CCUE 1N8RG 4WCEE 4WFBE 2CQLA 1K9MG 1VQPE 3PIOE 3CMEE 1S72E 3G71E 1VQ7E 3J7ZG 1KD1G 3CCSE 1Q86G 2ZJQE 1VQ8E 2OTLE
chains in the Genus database with same CATH superfamily
1KC8G 1VQNE 2OY5O 3CC2E 4WFNE 5JVGE 3I56E 1W2BE 1RL6A 1QVFE 1YJ9E 1VQ5E 1OSPO 3CKGA 5DM7E 3CKFA 3CCJE 2OY1O 2I5ZO 3OW2E 1JJ2E 1VQ6E 1QVGE 1YHQE 1Q82G 1Q81G 3CPWE 4U67E 3CC7E 2QEXE 3G4SE 2OTJE 1VQME 2OL8O 3CD6E 1VQ4E 5HL7E 1RJLC 2PI3O 3PIPE 5DM6E 3CMAE 5GADG 1Q7YG 3G6EE 5B2AO 5GAHG 1P4PA 3CCVE 3CCRE 1K73G 3CXCE 1YJNE 4UY8G 3CCLE 2OY8A 5GAGG 5B11O 5MLCH 5GAEG 3CCQE 1M1KG 3CCME 2G8CO 4IOAE 3IG9A 1YIJE 3IGEA 2OY7A 4IO9E 2OL7A 2ZJPE 5AN9B 1YJWE 4IOCE 1VQKE 2QA4E 2FKJA 2HKDA 5H1SI 3I55E 1FJ1E 1YI2E 3DLLE 1NJIG 1M90G 4WF9E 1K8AG 2FKGA 2OYBO 3CC4E 3CF5E 1VQOE 4WFAE 5B10O 1VQLE 2I5VO 1VQ9E 3CCEE 1KQSE 1YITE 5JVHE 2ZJRE 3CCUE 1N8RG 2OL6O 4WCEE 4WFBE 2CQLA 3AUMO 2AF5A 1K9MG 1VQPE 3PIOE 5B3MO 3CMEE 1S72E 3G71E 1VQ7E 3J7ZG 1KD1G 3CCSE 1Q86G 2ZJQE 3EC5A 1VQ8E 2OTLE
chains in the Genus database with same CATH topology
1KC8G 1VQNE 3CC2E 4WFNE 5JVGE 3I56E 1W2BE 1RL6A 1QVFE 1YJ9E 1VQ5E 5DM7E 3CCJE 3OW2E 1JJ2E 1VQ6E 1QVGE 1YHQE 1Q82G 1Q81G 3CPWE 4U67E 3CC7E 2QEXE 3G4SE 2OTJE 1VQME 3CD6E 1VQ4E 5HL7E 3PIPE 5DM6E 3CMAE 5GADG 1Q7YG 3G6EE 5GAHG 3CCVE 3CCRE 1K73G 3CXCE 1YJNE 4UY8G 3CCLE 5GAGG 5MLCH 5GAEG 3CCQE 1M1KG 3CCME 4IOAE 1YIJE 4IO9E 2ZJPE 5AN9B 1YJWE 4IOCE 1VQKE 2QA4E 5H1SI 3I55E 1YI2E 3DLLE 1NJIG 1M90G 4WF9E 1K8AG 3CC4E 3CF5E 1VQOE 4WFAE 1VQLE 1VQ9E 3CCEE 1KQSE 1YITE 5JVHE 2ZJRE 3CCUE 1N8RG 4WCEE 4WFBE 2CQLA 1K9MG 1VQPE 3PIOE 3CMEE 1S72E 3G71E 1VQ7E 3J7ZG 1KD1G 3CCSE 1Q86G 2ZJQE 1VQ8E 2OTLE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KC8 G;  1VQN E;  3CC2 E;  4WFN E;  5JVG E;  3I56 E;  1W2B E;  1RL6 A;  1QVF E;  1YJ9 E;  1VQ5 E;  5DM7 E;  3CCJ E;  3OW2 E;  1JJ2 E;  1VQ6 E;  1QVG E;  1YHQ E;  1Q82 G;  1Q81 G;  3CPW E;  4U67 E;  3CC7 E;  2QEX E;  3G4S E;  2OTJ E;  1VQM E;  3CD6 E;  1VQ4 E;  5HL7 E;  3PIP E;  5DM6 E;  3CMA E;  5GAD G;  1Q7Y G;  3G6E E;  5GAH G;  3CCV E;  3CCR E;  1K73 G;  3CXC E;  1YJN E;  4UY8 G;  3CCL E;  5GAG G;  5MLC H;  5GAE G;  3CCQ E;  1M1K G;  3CCM E;  4IOA E;  1YIJ E;  4IO9 E;  2ZJP E;  5AN9 B;  1YJW E;  4IOC E;  1VQK E;  2QA4 E;  5H1S I;  3I55 E;  1YI2 E;  3DLL E;  1NJI G;  1M90 G;  4WF9 E;  1K8A G;  3CC4 E;  3CF5 E;  1VQO E;  4WFA E;  1VQL E;  1VQ9 E;  3CCE E;  1KQS E;  1YIT E;  5JVH E;  2ZJR E;  3CCU E;  1N8R G;  4WCE E;  4WFB E;  2CQL A;  1K9M G;  1VQP E;  3PIO E;  3CME E;  1S72 E;  3G71 E;  1VQ7 E;  3J7Z G;  1KD1 G;  3CCS E;  1Q86 G;  2ZJQ E;  1VQ8 E;  2OTL E; 
#chains in the Genus database with same CATH topology
 1KC8 G;  1VQN E;  2OY5 O;  3CC2 E;  4WFN E;  5JVG E;  3I56 E;  1W2B E;  1RL6 A;  1QVF E;  1YJ9 E;  1VQ5 E;  1OSP O;  3CKG A;  5DM7 E;  3CKF A;  3CCJ E;  2OY1 O;  2I5Z O;  3OW2 E;  1JJ2 E;  1VQ6 E;  1QVG E;  1YHQ E;  1Q82 G;  1Q81 G;  3CPW E;  4U67 E;  3CC7 E;  2QEX E;  3G4S E;  2OTJ E;  1VQM E;  2OL8 O;  3CD6 E;  1VQ4 E;  5HL7 E;  1RJL C;  2PI3 O;  3PIP E;  5DM6 E;  3CMA E;  5GAD G;  1Q7Y G;  3G6E E;  5B2A O;  5GAH G;  1P4P A;  3CCV E;  3CCR E;  1K73 G;  3CXC E;  1YJN E;  4UY8 G;  3CCL E;  2OY8 A;  5GAG G;  5B11 O;  5MLC H;  5GAE G;  3CCQ E;  1M1K G;  3CCM E;  2G8C O;  4IOA E;  3IG9 A;  1YIJ E;  3IGE A;  2OY7 A;  4IO9 E;  2OL7 A;  2ZJP E;  5AN9 B;  1YJW E;  4IOC E;  1VQK E;  2QA4 E;  2FKJ A;  2HKD A;  5H1S I;  3I55 E;  1FJ1 E;  1YI2 E;  3DLL E;  1NJI G;  1M90 G;  4WF9 E;  1K8A G;  2FKG A;  2OYB O;  3CC4 E;  3CF5 E;  1VQO E;  4WFA E;  5B10 O;  1VQL E;  2I5V O;  1VQ9 E;  3CCE E;  1KQS E;  1YIT E;  5JVH E;  2ZJR E;  3CCU E;  1N8R G;  2OL6 O;  4WCE E;  4WFB E;  2CQL A;  3AUM O;  2AF5 A;  1K9M G;  1VQP E;  3PIO E;  5B3M O;  3CME E;  1S72 E;  3G71 E;  1VQ7 E;  3J7Z G;  1KD1 G;  3CCS E;  1Q86 G;  2ZJQ E;  3EC5 A;  1VQ8 E;  2OTL E; 
#chains in the Genus database with same CATH homology
 1KC8 G;  1VQN E;  3CC2 E;  4WFN E;  5JVG E;  3I56 E;  1W2B E;  1RL6 A;  1QVF E;  1YJ9 E;  1VQ5 E;  5DM7 E;  3CCJ E;  3OW2 E;  1JJ2 E;  1VQ6 E;  1QVG E;  1YHQ E;  1Q82 G;  1Q81 G;  3CPW E;  4U67 E;  3CC7 E;  2QEX E;  3G4S E;  2OTJ E;  1VQM E;  3CD6 E;  1VQ4 E;  5HL7 E;  3PIP E;  5DM6 E;  3CMA E;  5GAD G;  1Q7Y G;  3G6E E;  5GAH G;  3CCV E;  3CCR E;  1K73 G;  3CXC E;  1YJN E;  4UY8 G;  3CCL E;  5GAG G;  5MLC H;  5GAE G;  3CCQ E;  1M1K G;  3CCM E;  4IOA E;  1YIJ E;  4IO9 E;  2ZJP E;  5AN9 B;  1YJW E;  4IOC E;  1VQK E;  2QA4 E;  5H1S I;  3I55 E;  1YI2 E;  3DLL E;  1NJI G;  1M90 G;  4WF9 E;  1K8A G;  3CC4 E;  3CF5 E;  1VQO E;  4WFA E;  1VQL E;  1VQ9 E;  3CCE E;  1KQS E;  1YIT E;  5JVH E;  2ZJR E;  3CCU E;  1N8R G;  4WCE E;  4WFB E;  2CQL A;  1K9M G;  1VQP E;  3PIO E;  3CME E;  1S72 E;  3G71 E;  1VQ7 E;  3J7Z G;  1KD1 G;  3CCS E;  1Q86 G;  2ZJQ E;  1VQ8 E;  2OTL E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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