4IO9E

Crystal structure of compound 4d bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 28
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4io9E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4io9E01
4WF9E 3I55E 3G6EE 3CC4E 5JVGE 1N8RG 1YJ9E 1K73G 3J7ZG 5MLCH 3CCUE 1YHQE 1VQ7E 4WFNE 1YITE 3CCME 5JVHE 1Q82G 1VQ4E 1KQSE 1QVFE 1KD1G 2CQLA 1KC8G 3CCSE 4IOCE 4WFAE 5GAGG 3DLLE 4WCEE 4U67E 2ZJPE 1Q81G 3CPWE 3CCLE 3CCRE 1VQ6E 1VQNE 2OTJE 1VQ5E 3CCQE 3CCJE 1RL6A 3CD6E 2QEXE 3G4SE 1M90G 5GADG 1VQKE 2ZJRE 1YIJE 3CF5E 1K8AG 5DM7E 1YI2E 5GAHG 1M1KG 5H1SI 3CC7E 5DM6E 3CXCE 5AN9B 1VQLE 1Q86G 1VQPE 1YJNE 4IOAE 1VQOE 1K9MG 3G71E 1W2BE 3CMEE 1VQ9E 4UY8G 1YJWE 2OTLE 3CCEE 3OW2E 1Q7YG 5HL7E 2QA4E 1VQ8E 2ZJQE 1NJIG 1S72E 1JJ2E 5GAEG 3CC2E 4IO9E 3I56E 4WFBE 1QVGE 1VQME 3CMAE 3PIPE 3CCVE 3PIOE
chains in the Genus database with same CATH superfamily
4WF9E 3I55E 3G6EE 5JVGE 3CC4E 1N8RG 1YJ9E 3CKFA 1K73G 3J7ZG 1OSPO 5MLCH 3CCUE 1YHQE 1VQ7E 4WFNE 1YITE 2OY1O 3CCME 5JVHE 2OL6O 1Q82G 2OYBO 1VQ4E 1KQSE 1QVFE 1KD1G 2CQLA 1KC8G 3CCSE 2OL8O 1RJLC 4IOCE 4WFAE 5GAGG 3DLLE 4WCEE 4U67E 2ZJPE 1Q81G 3CPWE 3CCLE 3CCRE 1VQ6E 1VQNE 5B3MO 2OTJE 3AUMO 2I5VO 2HKDA 1VQ5E 3CCQE 3CCJE 1RL6A 3CD6E 2QEXE 3G4SE 1M90G 5GADG 1VQKE 3EC5A 2ZJRE 1YIJE 2OY5O 3CF5E 1K8AG 2PI3O 5DM7E 1YI2E 1P4PA 3IGEA 2I5ZO 5GAHG 1M1KG 5H1SI 3CC7E 5DM6E 3CXCE 5AN9B 1VQLE 1Q86G 2AF5A 1VQPE 1YJNE 4IOAE 1VQOE 1K9MG 3G71E 1W2BE 1FJ1E 3CMEE 2FKGA 1VQ9E 5B10O 4UY8G 2G8CO 1YJWE 2OTLE 3CCEE 3OW2E 2OL7A 1Q7YG 5HL7E 2QA4E 1VQ8E 2FKJA 3CKGA 5B2AO 2ZJQE 1NJIG 2OY8A 3IG9A 1S72E 1JJ2E 5GAEG 3CC2E 4IO9E 2OY7A 3I56E 4WFBE 1QVGE 1VQME 3CMAE 5B11O 3PIPE 3CCVE 3PIOE
chains in the Genus database with same CATH topology
4WF9E 3I55E 3G6EE 3CC4E 5JVGE 1N8RG 1YJ9E 1K73G 3J7ZG 5MLCH 3CCUE 1YHQE 1VQ7E 4WFNE 1YITE 3CCME 5JVHE 1Q82G 1VQ4E 1KQSE 1QVFE 1KD1G 2CQLA 1KC8G 3CCSE 4IOCE 4WFAE 5GAGG 3DLLE 4WCEE 4U67E 2ZJPE 1Q81G 3CPWE 3CCLE 3CCRE 1VQ6E 1VQNE 2OTJE 1VQ5E 3CCQE 3CCJE 1RL6A 3CD6E 2QEXE 3G4SE 1M90G 5GADG 1VQKE 2ZJRE 1YIJE 3CF5E 1K8AG 5DM7E 1YI2E 5GAHG 1M1KG 5H1SI 3CC7E 5DM6E 3CXCE 5AN9B 1VQLE 1Q86G 1VQPE 1YJNE 4IOAE 1VQOE 1K9MG 3G71E 1W2BE 3CMEE 1VQ9E 4UY8G 1YJWE 2OTLE 3CCEE 3OW2E 1Q7YG 5HL7E 2QA4E 1VQ8E 2ZJQE 1NJIG 1S72E 1JJ2E 5GAEG 3CC2E 4IO9E 3I56E 4WFBE 1QVGE 1VQME 3CMAE 3PIPE 3CCVE 3PIOE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WF9 E;  3I55 E;  3G6E E;  3CC4 E;  5JVG E;  1N8R G;  1YJ9 E;  1K73 G;  3J7Z G;  5MLC H;  3CCU E;  1YHQ E;  1VQ7 E;  4WFN E;  1YIT E;  3CCM E;  5JVH E;  1Q82 G;  1VQ4 E;  1KQS E;  1QVF E;  1KD1 G;  2CQL A;  1KC8 G;  3CCS E;  4IOC E;  4WFA E;  5GAG G;  3DLL E;  4WCE E;  4U67 E;  2ZJP E;  1Q81 G;  3CPW E;  3CCL E;  3CCR E;  1VQ6 E;  1VQN E;  2OTJ E;  1VQ5 E;  3CCQ E;  3CCJ E;  1RL6 A;  3CD6 E;  2QEX E;  3G4S E;  1M90 G;  5GAD G;  1VQK E;  2ZJR E;  1YIJ E;  3CF5 E;  1K8A G;  5DM7 E;  1YI2 E;  5GAH G;  1M1K G;  5H1S I;  3CC7 E;  5DM6 E;  3CXC E;  5AN9 B;  1VQL E;  1Q86 G;  1VQP E;  1YJN E;  4IOA E;  1VQO E;  1K9M G;  3G71 E;  1W2B E;  3CME E;  1VQ9 E;  4UY8 G;  1YJW E;  2OTL E;  3CCE E;  3OW2 E;  1Q7Y G;  5HL7 E;  2QA4 E;  1VQ8 E;  2ZJQ E;  1NJI G;  1S72 E;  1JJ2 E;  5GAE G;  3CC2 E;  4IO9 E;  3I56 E;  4WFB E;  1QVG E;  1VQM E;  3CMA E;  3PIP E;  3CCV E;  3PIO E; 
#chains in the Genus database with same CATH topology
 4WF9 E;  3I55 E;  3G6E E;  5JVG E;  3CC4 E;  1N8R G;  1YJ9 E;  3CKF A;  1K73 G;  3J7Z G;  1OSP O;  5MLC H;  3CCU E;  1YHQ E;  1VQ7 E;  4WFN E;  1YIT E;  2OY1 O;  3CCM E;  5JVH E;  2OL6 O;  1Q82 G;  2OYB O;  1VQ4 E;  1KQS E;  1QVF E;  1KD1 G;  2CQL A;  1KC8 G;  3CCS E;  2OL8 O;  1RJL C;  4IOC E;  4WFA E;  5GAG G;  3DLL E;  4WCE E;  4U67 E;  2ZJP E;  1Q81 G;  3CPW E;  3CCL E;  3CCR E;  1VQ6 E;  1VQN E;  5B3M O;  2OTJ E;  3AUM O;  2I5V O;  2HKD A;  1VQ5 E;  3CCQ E;  3CCJ E;  1RL6 A;  3CD6 E;  2QEX E;  3G4S E;  1M90 G;  5GAD G;  1VQK E;  3EC5 A;  2ZJR E;  1YIJ E;  2OY5 O;  3CF5 E;  1K8A G;  2PI3 O;  5DM7 E;  1YI2 E;  1P4P A;  3IGE A;  2I5Z O;  5GAH G;  1M1K G;  5H1S I;  3CC7 E;  5DM6 E;  3CXC E;  5AN9 B;  1VQL E;  1Q86 G;  2AF5 A;  1VQP E;  1YJN E;  4IOA E;  1VQO E;  1K9M G;  3G71 E;  1W2B E;  1FJ1 E;  3CME E;  2FKG A;  1VQ9 E;  5B10 O;  4UY8 G;  2G8C O;  1YJW E;  2OTL E;  3CCE E;  3OW2 E;  2OL7 A;  1Q7Y G;  5HL7 E;  2QA4 E;  1VQ8 E;  2FKJ A;  3CKG A;  5B2A O;  2ZJQ E;  1NJI G;  2OY8 A;  3IG9 A;  1S72 E;  1JJ2 E;  5GAE G;  3CC2 E;  4IO9 E;  2OY7 A;  3I56 E;  4WFB E;  1QVG E;  1VQM E;  3CMA E;  5B11 O;  3PIP E;  3CCV E;  3PIO E; 
#chains in the Genus database with same CATH homology
 4WF9 E;  3I55 E;  3G6E E;  3CC4 E;  5JVG E;  1N8R G;  1YJ9 E;  1K73 G;  3J7Z G;  5MLC H;  3CCU E;  1YHQ E;  1VQ7 E;  4WFN E;  1YIT E;  3CCM E;  5JVH E;  1Q82 G;  1VQ4 E;  1KQS E;  1QVF E;  1KD1 G;  2CQL A;  1KC8 G;  3CCS E;  4IOC E;  4WFA E;  5GAG G;  3DLL E;  4WCE E;  4U67 E;  2ZJP E;  1Q81 G;  3CPW E;  3CCL E;  3CCR E;  1VQ6 E;  1VQN E;  2OTJ E;  1VQ5 E;  3CCQ E;  3CCJ E;  1RL6 A;  3CD6 E;  2QEX E;  3G4S E;  1M90 G;  5GAD G;  1VQK E;  2ZJR E;  1YIJ E;  3CF5 E;  1K8A G;  5DM7 E;  1YI2 E;  5GAH G;  1M1K G;  5H1S I;  3CC7 E;  5DM6 E;  3CXC E;  5AN9 B;  1VQL E;  1Q86 G;  1VQP E;  1YJN E;  4IOA E;  1VQO E;  1K9M G;  3G71 E;  1W2B E;  3CME E;  1VQ9 E;  4UY8 G;  1YJW E;  2OTL E;  3CCE E;  3OW2 E;  1Q7Y G;  5HL7 E;  2QA4 E;  1VQ8 E;  2ZJQ E;  1NJI G;  1S72 E;  1JJ2 E;  5GAE G;  3CC2 E;  4IO9 E;  3I56 E;  4WFB E;  1QVG E;  1VQM E;  3CMA E;  3PIP E;  3CCV E;  3PIO E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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