4IOAE

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4ioaE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4ioaE01
3G6EE 3CCJE 3CCSE 3DLLE 5H1SI 3G4SE 3CCQE 3CXCE 1VQ4E 5JVGE 5MLCH 5HL7E 3I55E 5DM6E 3CCRE 1VQPE 5GAHG 1JJ2E 2CQLA 1RL6A 2OTJE 1W2BE 3CPWE 3CCME 3CMAE 5AN9B 1YITE 1YHQE 1KQSE 3G71E 2ZJQE 3CC4E 1N8RG 1Q7YG 1KC8G 4WFBE 1VQ7E 1VQ5E 5JVHE 1VQNE 1NJIG 2ZJPE 2ZJRE 1YIJE 1VQKE 4WFAE 5GADG 2QA4E 3PIPE 1Q86G 4WF9E 3CF5E 5GAGG 4IOAE 5GAEG 4UY8G 4WCEE 4U67E 1M90G 3CCUE 4WFNE 1VQOE 1Q81G 1QVGE 1VQLE 1Q82G 1YJNE 1K8AG 3CC2E 1S72E 4IOCE 1VQ6E 3CCVE 1K73G 1M1KG 1K9MG 3CCEE 1KD1G 5DM7E 3I56E 3CD6E 1VQ9E 1VQ8E 4IO9E 1QVFE 3PIOE 3CCLE 3CC7E 1YI2E 1YJWE 1YJ9E 2QEXE 2OTLE 3J7ZG 3OW2E 1VQME 3CMEE
chains in the Genus database with same CATH superfamily
3G6EE 3CCJE 3CCSE 3DLLE 5H1SI 3G4SE 3CCQE 5B2AO 3CXCE 1VQ4E 5JVGE 5MLCH 5HL7E 3I55E 2I5VO 5DM6E 3CCRE 1VQPE 5GAHG 1JJ2E 2CQLA 1RL6A 2OTJE 3CPWE 3CCME 1W2BE 3CMAE 3EC5A 5AN9B 1YITE 1YHQE 1KQSE 3G71E 1P4PA 5B10O 2ZJQE 3CC4E 1N8RG 1Q7YG 1KC8G 4WFBE 1VQ7E 1VQ5E 5JVHE 1VQNE 3IGEA 1NJIG 2OL7A 3CKGA 2ZJPE 2ZJRE 1YIJE 1VQKE 4WFAE 3IG9A 5GADG 2QA4E 3PIPE 2I5ZO 1Q86G 4WF9E 3CF5E 5GAGG 4IOAE 2OY8A 5GAEG 4UY8G 4WCEE 2FKJA 4U67E 1M90G 3CCUE 4WFNE 2PI3O 1RJLC 1VQOE 1Q81G 5B3MO 2OY5O 1FJ1E 1QVGE 1VQLE 2OL6O 1Q82G 2AF5A 1YJNE 1K8AG 3CC2E 1S72E 4IOCE 1VQ6E 3CCVE 1K73G 1M1KG 1K9MG 3CCEE 3CKFA 1OSPO 1KD1G 5DM7E 3I56E 2FKGA 3CD6E 5B11O 1VQ9E 2OYBO 1VQ8E 4IO9E 1QVFE 3PIOE 3CCLE 3CC7E 3AUMO 1YI2E 1YJWE 2OY1O 2G8CO 2OY7A 1YJ9E 2HKDA 2QEXE 2OTLE 3J7ZG 2OL8O 3OW2E 1VQME 3CMEE
chains in the Genus database with same CATH topology
3G6EE 3CCJE 3CCSE 3DLLE 5H1SI 3G4SE 3CCQE 3CXCE 1VQ4E 5JVGE 5MLCH 5HL7E 3I55E 5DM6E 3CCRE 1VQPE 5GAHG 1JJ2E 2CQLA 1RL6A 2OTJE 1W2BE 3CPWE 3CCME 3CMAE 5AN9B 1YITE 1YHQE 1KQSE 3G71E 2ZJQE 3CC4E 1N8RG 1Q7YG 1KC8G 4WFBE 1VQ7E 1VQ5E 5JVHE 1VQNE 1NJIG 2ZJPE 2ZJRE 1YIJE 1VQKE 4WFAE 5GADG 2QA4E 3PIPE 1Q86G 4WF9E 3CF5E 5GAGG 4IOAE 5GAEG 4UY8G 4WCEE 4U67E 1M90G 3CCUE 4WFNE 1VQOE 1Q81G 1QVGE 1VQLE 1Q82G 1YJNE 1K8AG 3CC2E 1S72E 4IOCE 1VQ6E 3CCVE 1K73G 1M1KG 1K9MG 3CCEE 1KD1G 5DM7E 3I56E 3CD6E 1VQ9E 1VQ8E 4IO9E 1QVFE 3PIOE 3CCLE 3CC7E 1YI2E 1YJWE 1YJ9E 2QEXE 2OTLE 3J7ZG 3OW2E 1VQME 3CMEE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E E;  3CCJ E;  3CCS E;  3DLL E;  5H1S I;  3G4S E;  3CCQ E;  3CXC E;  1VQ4 E;  5JVG E;  5MLC H;  5HL7 E;  3I55 E;  5DM6 E;  3CCR E;  1VQP E;  5GAH G;  1JJ2 E;  2CQL A;  1RL6 A;  2OTJ E;  1W2B E;  3CPW E;  3CCM E;  3CMA E;  5AN9 B;  1YIT E;  1YHQ E;  1KQS E;  3G71 E;  2ZJQ E;  3CC4 E;  1N8R G;  1Q7Y G;  1KC8 G;  4WFB E;  1VQ7 E;  1VQ5 E;  5JVH E;  1VQN E;  1NJI G;  2ZJP E;  2ZJR E;  1YIJ E;  1VQK E;  4WFA E;  5GAD G;  2QA4 E;  3PIP E;  1Q86 G;  4WF9 E;  3CF5 E;  5GAG G;  4IOA E;  5GAE G;  4UY8 G;  4WCE E;  4U67 E;  1M90 G;  3CCU E;  4WFN E;  1VQO E;  1Q81 G;  1QVG E;  1VQL E;  1Q82 G;  1YJN E;  1K8A G;  3CC2 E;  1S72 E;  4IOC E;  1VQ6 E;  3CCV E;  1K73 G;  1M1K G;  1K9M G;  3CCE E;  1KD1 G;  5DM7 E;  3I56 E;  3CD6 E;  1VQ9 E;  1VQ8 E;  4IO9 E;  1QVF E;  3PIO E;  3CCL E;  3CC7 E;  1YI2 E;  1YJW E;  1YJ9 E;  2QEX E;  2OTL E;  3J7Z G;  3OW2 E;  1VQM E;  3CME E; 
#chains in the Genus database with same CATH topology
 3G6E E;  3CCJ E;  3CCS E;  3DLL E;  5H1S I;  3G4S E;  3CCQ E;  5B2A O;  3CXC E;  1VQ4 E;  5JVG E;  5MLC H;  5HL7 E;  3I55 E;  2I5V O;  5DM6 E;  3CCR E;  1VQP E;  5GAH G;  1JJ2 E;  2CQL A;  1RL6 A;  2OTJ E;  3CPW E;  3CCM E;  1W2B E;  3CMA E;  3EC5 A;  5AN9 B;  1YIT E;  1YHQ E;  1KQS E;  3G71 E;  1P4P A;  5B10 O;  2ZJQ E;  3CC4 E;  1N8R G;  1Q7Y G;  1KC8 G;  4WFB E;  1VQ7 E;  1VQ5 E;  5JVH E;  1VQN E;  3IGE A;  1NJI G;  2OL7 A;  3CKG A;  2ZJP E;  2ZJR E;  1YIJ E;  1VQK E;  4WFA E;  3IG9 A;  5GAD G;  2QA4 E;  3PIP E;  2I5Z O;  1Q86 G;  4WF9 E;  3CF5 E;  5GAG G;  4IOA E;  2OY8 A;  5GAE G;  4UY8 G;  4WCE E;  2FKJ A;  4U67 E;  1M90 G;  3CCU E;  4WFN E;  2PI3 O;  1RJL C;  1VQO E;  1Q81 G;  5B3M O;  2OY5 O;  1FJ1 E;  1QVG E;  1VQL E;  2OL6 O;  1Q82 G;  2AF5 A;  1YJN E;  1K8A G;  3CC2 E;  1S72 E;  4IOC E;  1VQ6 E;  3CCV E;  1K73 G;  1M1K G;  1K9M G;  3CCE E;  3CKF A;  1OSP O;  1KD1 G;  5DM7 E;  3I56 E;  2FKG A;  3CD6 E;  5B11 O;  1VQ9 E;  2OYB O;  1VQ8 E;  4IO9 E;  1QVF E;  3PIO E;  3CCL E;  3CC7 E;  3AUM O;  1YI2 E;  1YJW E;  2OY1 O;  2G8C O;  2OY7 A;  1YJ9 E;  2HKD A;  2QEX E;  2OTL E;  3J7Z G;  2OL8 O;  3OW2 E;  1VQM E;  3CME E; 
#chains in the Genus database with same CATH homology
 3G6E E;  3CCJ E;  3CCS E;  3DLL E;  5H1S I;  3G4S E;  3CCQ E;  3CXC E;  1VQ4 E;  5JVG E;  5MLC H;  5HL7 E;  3I55 E;  5DM6 E;  3CCR E;  1VQP E;  5GAH G;  1JJ2 E;  2CQL A;  1RL6 A;  2OTJ E;  1W2B E;  3CPW E;  3CCM E;  3CMA E;  5AN9 B;  1YIT E;  1YHQ E;  1KQS E;  3G71 E;  2ZJQ E;  3CC4 E;  1N8R G;  1Q7Y G;  1KC8 G;  4WFB E;  1VQ7 E;  1VQ5 E;  5JVH E;  1VQN E;  1NJI G;  2ZJP E;  2ZJR E;  1YIJ E;  1VQK E;  4WFA E;  5GAD G;  2QA4 E;  3PIP E;  1Q86 G;  4WF9 E;  3CF5 E;  5GAG G;  4IOA E;  5GAE G;  4UY8 G;  4WCE E;  4U67 E;  1M90 G;  3CCU E;  4WFN E;  1VQO E;  1Q81 G;  1QVG E;  1VQL E;  1Q82 G;  1YJN E;  1K8A G;  3CC2 E;  1S72 E;  4IOC E;  1VQ6 E;  3CCV E;  1K73 G;  1M1K G;  1K9M G;  3CCE E;  1KD1 G;  5DM7 E;  3I56 E;  3CD6 E;  1VQ9 E;  1VQ8 E;  4IO9 E;  1QVF E;  3PIO E;  3CCL E;  3CC7 E;  1YI2 E;  1YJW E;  1YJ9 E;  2QEX E;  2OTL E;  3J7Z G;  3OW2 E;  1VQM E;  3CME E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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