4IOCE

Crystal structure of compound 4f bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
171
structure length
171
Chain Sequence
GKQPIAVPSGVTVNAQDGVFKVKGPKGELTVPYNTELTVRQDGDQLLVERPSDAQKHRALHGLTRTLVANAVKGVSDGYTINLELRGVGFRAKLTGKALEMNIGYSHPVIIEPPAGVTFAVPEPTRIDVSGIDKQLVGQVAANVRKVRKPDAYHGKGVRFVGEQIALKAGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4iocE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 4iocE01
3CCEE 1YJ9E 5GAEG 1JJ2E 1S72E 4WF9E 1QVFE 1VQME 5JVHE 3CCUE 1YJNE 1Q86G 5GAGG 1N8RG 4U67E 1Q7YG 4IOCE 1YI2E 3CCSE 3CC7E 1VQ6E 3G4SE 3OW2E 1VQ8E 1KQSE 3G71E 1K8AG 3CCME 5HL7E 4WCEE 2CQLA 2ZJRE 2OTLE 2QEXE 1K73G 3CD6E 2OTJE 1VQ7E 1KC8G 5JVGE 1NJIG 5H1SI 2ZJPE 1YIJE 4WFNE 1VQ9E 3CC4E 3CCRE 4IO9E 1RL6A 3J7ZG 3PIPE 2QA4E 5DM6E 1W2BE 1VQLE 1M90G 1VQNE 5AN9B 1Q82G 1VQKE 3I55E 3CCVE 1QVGE 5GAHG 1YHQE 3CC2E 5MLCH 3DLLE 3CCLE 3CF5E 4WFAE 3CPWE 3G6EE 3CXCE 3CCJE 1M1KG 3CMEE 1YITE 1VQ4E 3PIOE 4UY8G 1VQPE 1VQOE 4WFBE 1VQ5E 2ZJQE 3CMAE 1KD1G 4IOAE 1YJWE 3I56E 3CCQE 1K9MG 1Q81G 5DM7E 5GADG
chains in the Genus database with same CATH superfamily
3CCEE 2OL8O 3IGEA 5B11O 1YJ9E 5GAEG 1JJ2E 1S72E 4WF9E 1QVFE 1VQME 5JVHE 1OSPO 3CCUE 1YJNE 1Q86G 5GAGG 1N8RG 4U67E 1Q7YG 4IOCE 1YI2E 3CCSE 3CC7E 1VQ6E 3G4SE 3OW2E 1VQ8E 1KQSE 3G71E 2G8CO 1K8AG 2OY8A 2PI3O 2HKDA 3CCME 5HL7E 4WCEE 2CQLA 2ZJRE 2OTLE 2QEXE 1K73G 3CD6E 2OTJE 1VQ7E 1KC8G 5JVGE 5B3MO 1NJIG 5B2AO 5H1SI 2ZJPE 1YIJE 3IG9A 2AF5A 4WFNE 1VQ9E 3AUMO 3CC4E 3CCRE 4IO9E 1RL6A 3J7ZG 3PIPE 2QA4E 5DM6E 2OY7A 1W2BE 1VQLE 1M90G 1VQNE 5AN9B 1Q82G 1FJ1E 1VQKE 3I55E 3CCVE 2OY5O 1QVGE 5GAHG 1YHQE 3CC2E 2OL7A 5MLCH 3DLLE 3CCLE 3CF5E 4WFAE 3CPWE 3G6EE 3CXCE 2OY1O 1RJLC 1P4PA 3CCJE 1M1KG 3CMEE 1YITE 2FKJA 1VQ4E 3PIOE 4UY8G 2I5VO 1VQPE 1VQOE 2I5ZO 5B10O 4WFBE 1VQ5E 2ZJQE 2FKGA 3CMAE 1KD1G 3CKFA 3EC5A 4IOAE 1YJWE 3I56E 3CCQE 1K9MG 2OYBO 2OL6O 3CKGA 1Q81G 5DM7E 5GADG
chains in the Genus database with same CATH topology
3CCEE 1YJ9E 5GAEG 1JJ2E 1S72E 4WF9E 1QVFE 1VQME 5JVHE 3CCUE 1YJNE 1Q86G 5GAGG 1N8RG 4U67E 1Q7YG 4IOCE 1YI2E 3CCSE 3CC7E 1VQ6E 3G4SE 3OW2E 1VQ8E 1KQSE 3G71E 1K8AG 3CCME 5HL7E 4WCEE 2CQLA 2ZJRE 2OTLE 2QEXE 1K73G 3CD6E 2OTJE 1VQ7E 1KC8G 5JVGE 1NJIG 5H1SI 2ZJPE 1YIJE 4WFNE 1VQ9E 3CC4E 3CCRE 4IO9E 1RL6A 3J7ZG 3PIPE 2QA4E 5DM6E 1W2BE 1VQLE 1M90G 1VQNE 5AN9B 1Q82G 1VQKE 3I55E 3CCVE 1QVGE 5GAHG 1YHQE 3CC2E 5MLCH 3DLLE 3CCLE 3CF5E 4WFAE 3CPWE 3G6EE 3CXCE 3CCJE 1M1KG 3CMEE 1YITE 1VQ4E 3PIOE 4UY8G 1VQPE 1VQOE 4WFBE 1VQ5E 2ZJQE 3CMAE 1KD1G 4IOAE 1YJWE 3I56E 3CCQE 1K9MG 1Q81G 5DM7E 5GADG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CCE E;  1YJ9 E;  5GAE G;  1JJ2 E;  1S72 E;  4WF9 E;  1QVF E;  1VQM E;  5JVH E;  3CCU E;  1YJN E;  1Q86 G;  5GAG G;  1N8R G;  4U67 E;  1Q7Y G;  4IOC E;  1YI2 E;  3CCS E;  3CC7 E;  1VQ6 E;  3G4S E;  3OW2 E;  1VQ8 E;  1KQS E;  3G71 E;  1K8A G;  3CCM E;  5HL7 E;  4WCE E;  2CQL A;  2ZJR E;  2OTL E;  2QEX E;  1K73 G;  3CD6 E;  2OTJ E;  1VQ7 E;  1KC8 G;  5JVG E;  1NJI G;  5H1S I;  2ZJP E;  1YIJ E;  4WFN E;  1VQ9 E;  3CC4 E;  3CCR E;  4IO9 E;  1RL6 A;  3J7Z G;  3PIP E;  2QA4 E;  5DM6 E;  1W2B E;  1VQL E;  1M90 G;  1VQN E;  5AN9 B;  1Q82 G;  1VQK E;  3I55 E;  3CCV E;  1QVG E;  5GAH G;  1YHQ E;  3CC2 E;  5MLC H;  3DLL E;  3CCL E;  3CF5 E;  4WFA E;  3CPW E;  3G6E E;  3CXC E;  3CCJ E;  1M1K G;  3CME E;  1YIT E;  1VQ4 E;  3PIO E;  4UY8 G;  1VQP E;  1VQO E;  4WFB E;  1VQ5 E;  2ZJQ E;  3CMA E;  1KD1 G;  4IOA E;  1YJW E;  3I56 E;  3CCQ E;  1K9M G;  1Q81 G;  5DM7 E;  5GAD G; 
#chains in the Genus database with same CATH topology
 3CCE E;  2OL8 O;  3IGE A;  5B11 O;  1YJ9 E;  5GAE G;  1JJ2 E;  1S72 E;  4WF9 E;  1QVF E;  1VQM E;  5JVH E;  1OSP O;  3CCU E;  1YJN E;  1Q86 G;  5GAG G;  1N8R G;  4U67 E;  1Q7Y G;  4IOC E;  1YI2 E;  3CCS E;  3CC7 E;  1VQ6 E;  3G4S E;  3OW2 E;  1VQ8 E;  1KQS E;  3G71 E;  2G8C O;  1K8A G;  2OY8 A;  2PI3 O;  2HKD A;  3CCM E;  5HL7 E;  4WCE E;  2CQL A;  2ZJR E;  2OTL E;  2QEX E;  1K73 G;  3CD6 E;  2OTJ E;  1VQ7 E;  1KC8 G;  5JVG E;  5B3M O;  1NJI G;  5B2A O;  5H1S I;  2ZJP E;  1YIJ E;  3IG9 A;  2AF5 A;  4WFN E;  1VQ9 E;  3AUM O;  3CC4 E;  3CCR E;  4IO9 E;  1RL6 A;  3J7Z G;  3PIP E;  2QA4 E;  5DM6 E;  2OY7 A;  1W2B E;  1VQL E;  1M90 G;  1VQN E;  5AN9 B;  1Q82 G;  1FJ1 E;  1VQK E;  3I55 E;  3CCV E;  2OY5 O;  1QVG E;  5GAH G;  1YHQ E;  3CC2 E;  2OL7 A;  5MLC H;  3DLL E;  3CCL E;  3CF5 E;  4WFA E;  3CPW E;  3G6E E;  3CXC E;  2OY1 O;  1RJL C;  1P4P A;  3CCJ E;  1M1K G;  3CME E;  1YIT E;  2FKJ A;  1VQ4 E;  3PIO E;  4UY8 G;  2I5V O;  1VQP E;  1VQO E;  2I5Z O;  5B10 O;  4WFB E;  1VQ5 E;  2ZJQ E;  2FKG A;  3CMA E;  1KD1 G;  3CKF A;  3EC5 A;  4IOA E;  1YJW E;  3I56 E;  3CCQ E;  1K9M G;  2OYB O;  2OL6 O;  3CKG A;  1Q81 G;  5DM7 E;  5GAD G; 
#chains in the Genus database with same CATH homology
 3CCE E;  1YJ9 E;  5GAE G;  1JJ2 E;  1S72 E;  4WF9 E;  1QVF E;  1VQM E;  5JVH E;  3CCU E;  1YJN E;  1Q86 G;  5GAG G;  1N8R G;  4U67 E;  1Q7Y G;  4IOC E;  1YI2 E;  3CCS E;  3CC7 E;  1VQ6 E;  3G4S E;  3OW2 E;  1VQ8 E;  1KQS E;  3G71 E;  1K8A G;  3CCM E;  5HL7 E;  4WCE E;  2CQL A;  2ZJR E;  2OTL E;  2QEX E;  1K73 G;  3CD6 E;  2OTJ E;  1VQ7 E;  1KC8 G;  5JVG E;  1NJI G;  5H1S I;  2ZJP E;  1YIJ E;  4WFN E;  1VQ9 E;  3CC4 E;  3CCR E;  4IO9 E;  1RL6 A;  3J7Z G;  3PIP E;  2QA4 E;  5DM6 E;  1W2B E;  1VQL E;  1M90 G;  1VQN E;  5AN9 B;  1Q82 G;  1VQK E;  3I55 E;  3CCV E;  1QVG E;  5GAH G;  1YHQ E;  3CC2 E;  5MLC H;  3DLL E;  3CCL E;  3CF5 E;  4WFA E;  3CPW E;  3G6E E;  3CXC E;  3CCJ E;  1M1K G;  3CME E;  1YIT E;  1VQ4 E;  3PIO E;  4UY8 G;  1VQP E;  1VQO E;  4WFB E;  1VQ5 E;  2ZJQ E;  3CMA E;  1KD1 G;  4IOA E;  1YJW E;  3I56 E;  3CCQ E;  1K9M G;  1Q81 G;  5DM7 E;  5GAD G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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