1AK4C

Human cyclophilin a bound to the amino-terminal domain of hiv-1 capsid
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
145
structure length
145
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
pubmed doi rcsb
molecule tags Viral protein/isomerase
source organism Homo sapiens
molecule keywords CYCLOPHILIN A
total genus 45
structure length 145
sequence length 145
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 1997-05-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1ak4C00
4LQWC 2KGFA 4B4NA 1D1DA 4E91A 2Y4ZA 4HTWA 4XFYA 2X83A 5HGOA 1QRJA 2XGYA 2XGVA 4WYMA 1EIAA 1E6JP 4PH2A 5HGMA 4U0EA 2WLVB 4DGAC 3H47A 4XRQA 1L6NA 5JPAA 4DGEC 1GWPA 1M9EC 3NTEA 3H4EA 3BP9A 5HGKA 2WLVA 4NX4C 2GONA 4PH0A 2X82A 4QNBA 1M9XC 2PWMA 1EM9A 1M9FC 4E92A 2M8NA 1G03A 4U0BA 1U7KA 1AFVA 2V4XA 4INBA 4XROA 2XDEA 4PH3A 4U0AA 2XGUA 4XFZA 1M9CC 5HGLA 5HGNA 2X2DD 3MGEA 2LF4A 1P7NA 4U0CA 2PXRC 4XFXA 4J93A 2GOLB 2M8PA 3P05A 2PWOA 2JPRA 4U0DA 1M9YC 1M9DC 2M8LA 2EIAA 4U0FA 1AK4C
chains in the Genus database with same CATH superfamily
4LQWC 2KGFA 4B4NA 1D1DA 4E91A 2Y4ZA 4HTWA 4XFYA 2X83A 5HGOA 1QRJA 2XGYA 2XGVA 4WYMA 1EIAA 1E6JP 4PH2A 5HGMA 4U0EA 2WLVB 4DGAC 3H47A 4XRQA 1L6NA 5JPAA 4DGEC 1GWPA 1M9EC 3NTEA 3H4EA 3BP9A 5HGKA 2WLVA 4NX4C 2GONA 4PH0A 2X82A 4QNBA 1M9XC 2PWMA 1EM9A 1M9FC 4E92A 2M8NA 1G03A 4U0BA 1U7KA 1AFVA 2V4XA 4INBA 4XROA 2XDEA 4PH3A 4U0AA 2XGUA 4XFZA 1M9CC 5HGLA 5HGNA 2X2DD 3MGEA 2LF4A 1P7NA 4U0CA 2PXRC 4XFXA 4J93A 2GOLB 2M8PA 3P05A 2PWOA 2JPRA 4U0DA 1M9YC 1M9DC 2M8LA 2EIAA 4U0FA 1AK4C
chains in the Genus database with same CATH topology
4LQWC 2KGFA 4B4NA 1D1DA 4E91A 2Y4ZA 4HTWA 4XFYA 2X83A 5HGOA 1QRJA 2XGYA 2XGVA 4WYMA 1EIAA 1E6JP 4PH2A 5HGMA 4U0EA 2WLVB 4DGAC 3H47A 4XRQA 1L6NA 5JPAA 4DGEC 1GWPA 1M9EC 3NTEA 3H4EA 3BP9A 5HGKA 2WLVA 4NX4C 2GONA 4PH0A 2X82A 4QNBA 1M9XC 2PWMA 1EM9A 1M9FC 4E92A 2M8NA 1G03A 4U0BA 1U7KA 1AFVA 2V4XA 4INBA 4XROA 2XDEA 4PH3A 4U0AA 2XGUA 4XFZA 1M9CC 5HGLA 5HGNA 2X2DD 3MGEA 2LF4A 1P7NA 4U0CA 2PXRC 4XFXA 4J93A 2GOLB 2M8PA 3P05A 2PWOA 2JPRA 4U0DA 1M9YC 1M9DC 2M8LA 2EIAA 4U0FA 1AK4C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LQW C;  2KGF A;  4B4N A;  1D1D A;  4E91 A;  2Y4Z A;  4HTW A;  4XFY A;  2X83 A;  5HGO A;  1QRJ A;  2XGY A;  2XGV A;  4WYM A;  1EIA A;  1E6J P;  4PH2 A;  5HGM A;  4U0E A;  2WLV B;  4DGA C;  3H47 A;  4XRQ A;  1L6N A;  5JPA A;  4DGE C;  1GWP A;  1M9E C;  3NTE A;  3H4E A;  3BP9 A;  5HGK A;  2WLV A;  4NX4 C;  2GON A;  4PH0 A;  2X82 A;  4QNB A;  1M9X C;  2PWM A;  1EM9 A;  1M9F C;  4E92 A;  2M8N A;  1G03 A;  4U0B A;  1U7K A;  1AFV A;  2V4X A;  4INB A;  4XRO A;  2XDE A;  4PH3 A;  4U0A A;  2XGU A;  4XFZ A;  1M9C C;  5HGL A;  5HGN A;  2X2D D;  3MGE A;  2LF4 A;  1P7N A;  4U0C A;  2PXR C;  4XFX A;  4J93 A;  2GOL B;  2M8P A;  3P05 A;  2PWO A;  2JPR A;  4U0D A;  1M9Y C;  1M9D C;  2M8L A;  2EIA A;  4U0F A;  1AK4 C; 
#chains in the Genus database with same CATH topology
 4LQW C;  2KGF A;  4B4N A;  1D1D A;  4E91 A;  2Y4Z A;  4HTW A;  4XFY A;  2X83 A;  5HGO A;  1QRJ A;  2XGY A;  2XGV A;  4WYM A;  1EIA A;  1E6J P;  4PH2 A;  5HGM A;  4U0E A;  2WLV B;  4DGA C;  3H47 A;  4XRQ A;  1L6N A;  5JPA A;  4DGE C;  1GWP A;  1M9E C;  3NTE A;  3H4E A;  3BP9 A;  5HGK A;  2WLV A;  4NX4 C;  2GON A;  4PH0 A;  2X82 A;  4QNB A;  1M9X C;  2PWM A;  1EM9 A;  1M9F C;  4E92 A;  2M8N A;  1G03 A;  4U0B A;  1U7K A;  1AFV A;  2V4X A;  4INB A;  4XRO A;  2XDE A;  4PH3 A;  4U0A A;  2XGU A;  4XFZ A;  1M9C C;  5HGL A;  5HGN A;  2X2D D;  3MGE A;  2LF4 A;  1P7N A;  4U0C A;  2PXR C;  4XFX A;  4J93 A;  2GOL B;  2M8P A;  3P05 A;  2PWO A;  2JPR A;  4U0D A;  1M9Y C;  1M9D C;  2M8L A;  2EIA A;  4U0F A;  1AK4 C; 
#chains in the Genus database with same CATH homology
 4LQW C;  2KGF A;  4B4N A;  1D1D A;  4E91 A;  2Y4Z A;  4HTW A;  4XFY A;  2X83 A;  5HGO A;  1QRJ A;  2XGY A;  2XGV A;  4WYM A;  1EIA A;  1E6J P;  4PH2 A;  5HGM A;  4U0E A;  2WLV B;  4DGA C;  3H47 A;  4XRQ A;  1L6N A;  5JPA A;  4DGE C;  1GWP A;  1M9E C;  3NTE A;  3H4E A;  3BP9 A;  5HGK A;  2WLV A;  4NX4 C;  2GON A;  4PH0 A;  2X82 A;  4QNB A;  1M9X C;  2PWM A;  1EM9 A;  1M9F C;  4E92 A;  2M8N A;  1G03 A;  4U0B A;  1U7K A;  1AFV A;  2V4X A;  4INB A;  4XRO A;  2XDE A;  4PH3 A;  4U0A A;  2XGU A;  4XFZ A;  1M9C C;  5HGL A;  5HGN A;  2X2D D;  3MGE A;  2LF4 A;  1P7N A;  4U0C A;  2PXR C;  4XFX A;  4J93 A;  2GOL B;  2M8P A;  3P05 A;  2PWO A;  2JPR A;  4U0D A;  1M9Y C;  1M9D C;  2M8L A;  2EIA A;  4U0F A;  1AK4 C; 
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similar chains in the pdb database (?% sequence similarity)

 
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