2X82A

Evolutionary basis of hiv restriction by the antiretroviral trimcyp
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
145
structure length
145
Chain Sequence
PVQHVGGTYTHIPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAAEWDVQHPIPAGPLPAGQLREPRGSDIAGTTSTVEEQIQWMFRPQNPVPVGNIYRRWIQIGLQKCVRMY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CAPSID PROTEIN P24
publication title Conformational Adaptation of Asian Macaque Trimcyp Directs Lineage Specific Antiviral Activity.
pubmed doi rcsb
source organism Human immunodeficiency virus type 2 (isolate d194)
molecule tags Viral protein
total genus 51
structure length 145
sequence length 145
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 2x82A00
2X2DD 2WLVA 2PWOA 1GWPA 1M9CC 4LQWC 4XFYA 4QNBA 4U0FA 1EIAA 3MGEA 2WLVB 2GOLB 4XFZA 3BP9A 4U0EA 1P7NA 2X82A 2LF4A 2M8NA 4XROA 2XGVA 4PH0A 1L6NA 2XGYA 2PXRC 2Y4ZA 4U0DA 1M9YC 2XDEA 1M9XC 2M8LA 2EIAA 2XGUA 1D1DA 4E92A 4B4NA 2V4XA 4U0CA 4WYMA 2KGFA 4XRQA 3H4EA 5HGNA 4E91A 1AK4C 4J93A 5HGLA 5HGKA 4XFXA 4DGEC 4PH2A 4DGAC 2GONA 1EM9A 4NX4C 5JPAA 4PH3A 2PWMA 3H47A 1M9EC 3NTEA 4INBA 1M9DC 5HGMA 1AFVA 4U0BA 2M8PA 1G03A 2JPRA 4U0AA 1U7KA 2X83A 1E6JP 3P05A 4HTWA 1QRJA 5HGOA 1M9FC
chains in the Genus database with same CATH superfamily
2X2DD 2WLVA 2PWOA 1GWPA 1M9CC 4LQWC 4XFYA 4QNBA 4U0FA 1EIAA 3MGEA 2WLVB 2GOLB 4XFZA 3BP9A 4U0EA 1P7NA 2X82A 2LF4A 2M8NA 4XROA 2XGVA 4PH0A 1L6NA 2XGYA 2PXRC 2Y4ZA 4U0DA 1M9YC 2XDEA 1M9XC 2M8LA 2EIAA 2XGUA 1D1DA 4E92A 4B4NA 2V4XA 4U0CA 4WYMA 2KGFA 4XRQA 3H4EA 5HGNA 4E91A 1AK4C 4J93A 5HGLA 5HGKA 4XFXA 4DGEC 4PH2A 4DGAC 2GONA 1EM9A 4NX4C 5JPAA 4PH3A 2PWMA 3H47A 1M9EC 3NTEA 4INBA 1M9DC 5HGMA 1AFVA 4U0BA 2M8PA 1G03A 2JPRA 4U0AA 1U7KA 2X83A 1E6JP 3P05A 4HTWA 1QRJA 5HGOA 1M9FC
chains in the Genus database with same CATH topology
2X2DD 2WLVA 2PWOA 1GWPA 1M9CC 4LQWC 4XFYA 4QNBA 4U0FA 1EIAA 3MGEA 2WLVB 2GOLB 4XFZA 3BP9A 4U0EA 1P7NA 2X82A 2LF4A 2M8NA 4XROA 2XGVA 4PH0A 1L6NA 2XGYA 2PXRC 2Y4ZA 4U0DA 1M9YC 2XDEA 1M9XC 2M8LA 2EIAA 2XGUA 1D1DA 4E92A 4B4NA 2V4XA 4U0CA 4WYMA 2KGFA 4XRQA 3H4EA 5HGNA 4E91A 1AK4C 4J93A 5HGLA 5HGKA 4XFXA 4DGEC 4PH2A 4DGAC 2GONA 1EM9A 4NX4C 5JPAA 4PH3A 2PWMA 3H47A 1M9EC 3NTEA 4INBA 1M9DC 5HGMA 1AFVA 4U0BA 2M8PA 1G03A 2JPRA 4U0AA 1U7KA 2X83A 1E6JP 3P05A 4HTWA 1QRJA 5HGOA 1M9FC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X2D D;  2WLV A;  2PWO A;  1GWP A;  1M9C C;  4LQW C;  4XFY A;  4QNB A;  4U0F A;  1EIA A;  3MGE A;  2WLV B;  2GOL B;  4XFZ A;  3BP9 A;  4U0E A;  1P7N A;  2X82 A;  2LF4 A;  2M8N A;  4XRO A;  2XGV A;  4PH0 A;  1L6N A;  2XGY A;  2PXR C;  2Y4Z A;  4U0D A;  1M9Y C;  2XDE A;  1M9X C;  2M8L A;  2EIA A;  2XGU A;  1D1D A;  4E92 A;  4B4N A;  2V4X A;  4U0C A;  4WYM A;  2KGF A;  4XRQ A;  3H4E A;  5HGN A;  4E91 A;  1AK4 C;  4J93 A;  5HGL A;  5HGK A;  4XFX A;  4DGE C;  4PH2 A;  4DGA C;  2GON A;  1EM9 A;  4NX4 C;  5JPA A;  4PH3 A;  2PWM A;  3H47 A;  1M9E C;  3NTE A;  4INB A;  1M9D C;  5HGM A;  1AFV A;  4U0B A;  2M8P A;  1G03 A;  2JPR A;  4U0A A;  1U7K A;  2X83 A;  1E6J P;  3P05 A;  4HTW A;  1QRJ A;  5HGO A;  1M9F C; 
#chains in the Genus database with same CATH topology
 2X2D D;  2WLV A;  2PWO A;  1GWP A;  1M9C C;  4LQW C;  4XFY A;  4QNB A;  4U0F A;  1EIA A;  3MGE A;  2WLV B;  2GOL B;  4XFZ A;  3BP9 A;  4U0E A;  1P7N A;  2X82 A;  2LF4 A;  2M8N A;  4XRO A;  2XGV A;  4PH0 A;  1L6N A;  2XGY A;  2PXR C;  2Y4Z A;  4U0D A;  1M9Y C;  2XDE A;  1M9X C;  2M8L A;  2EIA A;  2XGU A;  1D1D A;  4E92 A;  4B4N A;  2V4X A;  4U0C A;  4WYM A;  2KGF A;  4XRQ A;  3H4E A;  5HGN A;  4E91 A;  1AK4 C;  4J93 A;  5HGL A;  5HGK A;  4XFX A;  4DGE C;  4PH2 A;  4DGA C;  2GON A;  1EM9 A;  4NX4 C;  5JPA A;  4PH3 A;  2PWM A;  3H47 A;  1M9E C;  3NTE A;  4INB A;  1M9D C;  5HGM A;  1AFV A;  4U0B A;  2M8P A;  1G03 A;  2JPR A;  4U0A A;  1U7K A;  2X83 A;  1E6J P;  3P05 A;  4HTW A;  1QRJ A;  5HGO A;  1M9F C; 
#chains in the Genus database with same CATH homology
 2X2D D;  2WLV A;  2PWO A;  1GWP A;  1M9C C;  4LQW C;  4XFY A;  4QNB A;  4U0F A;  1EIA A;  3MGE A;  2WLV B;  2GOL B;  4XFZ A;  3BP9 A;  4U0E A;  1P7N A;  2X82 A;  2LF4 A;  2M8N A;  4XRO A;  2XGV A;  4PH0 A;  1L6N A;  2XGY A;  2PXR C;  2Y4Z A;  4U0D A;  1M9Y C;  2XDE A;  1M9X C;  2M8L A;  2EIA A;  2XGU A;  1D1D A;  4E92 A;  4B4N A;  2V4X A;  4U0C A;  4WYM A;  2KGF A;  4XRQ A;  3H4E A;  5HGN A;  4E91 A;  1AK4 C;  4J93 A;  5HGL A;  5HGK A;  4XFX A;  4DGE C;  4PH2 A;  4DGA C;  2GON A;  1EM9 A;  4NX4 C;  5JPA A;  4PH3 A;  2PWM A;  3H47 A;  1M9E C;  3NTE A;  4INB A;  1M9D C;  5HGM A;  1AFV A;  4U0B A;  2M8P A;  1G03 A;  2JPR A;  4U0A A;  1U7K A;  2X83 A;  1E6J P;  3P05 A;  4HTW A;  1QRJ A;  5HGO A;  1M9F C; 
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similar chains in the pdb database (?% sequence similarity)

 
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