4DGAC

Trimcyp cyclophilin domain from macaca mulatta: hiv-1 ca(o-loop) complex
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
145
structure length
138
Chain Sequence
PIVVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPTGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Macaca mulatta
molecule keywords TRIMCyp
total genus 48
structure length 138
sequence length 145
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-01-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4dgaC00
2EIAA 2M8LA 4E92A 4INBA 4NX4C 2X2DD 4HTWA 4DGAC 4XFZA 4B4NA 1M9YC 4XFXA 5HGLA 3P05A 3H4EA 4WYMA 3NTEA 2M8PA 1M9DC 2KGFA 1GWPA 2WLVB 3H47A 1L6NA 4U0DA 1M9FC 5HGMA 1M9CC 4QNBA 1G03A 2LF4A 2X83A 4E91A 4U0BA 1M9EC 2PWOA 1QRJA 2X82A 4PH0A 2XGYA 1EM9A 1U7KA 4PH3A 2M8NA 2Y4ZA 2PWMA 5JPAA 2PXRC 2V4XA 1AFVA 4U0FA 4XROA 1D1DA 1M9XC 2GONA 5HGOA 4XRQA 4DGEC 2WLVA 4XFYA 4PH2A 4U0CA 2XDEA 1AK4C 4LQWC 4U0AA 2GOLB 5HGNA 1P7NA 2JPRA 4U0EA 4J93A 5HGKA 2XGVA 3MGEA 2XGUA 1EIAA 3BP9A 1E6JP
chains in the Genus database with same CATH superfamily
2EIAA 2M8LA 4E92A 4INBA 4NX4C 2X2DD 4HTWA 4DGAC 4XFZA 4B4NA 1M9YC 4XFXA 5HGLA 3P05A 3H4EA 4WYMA 3NTEA 2M8PA 1M9DC 2KGFA 1GWPA 2WLVB 3H47A 1L6NA 4U0DA 1M9FC 5HGMA 1M9CC 4QNBA 1G03A 2LF4A 2X83A 4E91A 4U0BA 1M9EC 2PWOA 1QRJA 2X82A 4PH0A 2XGYA 1EM9A 1U7KA 4PH3A 2M8NA 2Y4ZA 2PWMA 5JPAA 2PXRC 2V4XA 1AFVA 4U0FA 4XROA 1D1DA 1M9XC 2GONA 5HGOA 4XRQA 4DGEC 2WLVA 4XFYA 4PH2A 4U0CA 2XDEA 1AK4C 4LQWC 4U0AA 2GOLB 5HGNA 1P7NA 2JPRA 4U0EA 4J93A 5HGKA 2XGVA 3MGEA 2XGUA 1EIAA 3BP9A 1E6JP
chains in the Genus database with same CATH topology
2EIAA 2M8LA 4E92A 4INBA 4NX4C 2X2DD 4HTWA 4DGAC 4XFZA 4B4NA 1M9YC 4XFXA 5HGLA 3P05A 3H4EA 4WYMA 3NTEA 2M8PA 1M9DC 2KGFA 1GWPA 2WLVB 3H47A 1L6NA 4U0DA 1M9FC 5HGMA 1M9CC 4QNBA 1G03A 2LF4A 2X83A 4E91A 4U0BA 1M9EC 2PWOA 1QRJA 2X82A 4PH0A 2XGYA 1EM9A 1U7KA 4PH3A 2M8NA 2Y4ZA 2PWMA 5JPAA 2PXRC 2V4XA 1AFVA 4U0FA 4XROA 1D1DA 1M9XC 2GONA 5HGOA 4XRQA 4DGEC 2WLVA 4XFYA 4PH2A 4U0CA 2XDEA 1AK4C 4LQWC 4U0AA 2GOLB 5HGNA 1P7NA 2JPRA 4U0EA 4J93A 5HGKA 2XGVA 3MGEA 2XGUA 1EIAA 3BP9A 1E6JP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EIA A;  2M8L A;  4E92 A;  4INB A;  4NX4 C;  2X2D D;  4HTW A;  4DGA C;  4XFZ A;  4B4N A;  1M9Y C;  4XFX A;  5HGL A;  3P05 A;  3H4E A;  4WYM A;  3NTE A;  2M8P A;  1M9D C;  2KGF A;  1GWP A;  2WLV B;  3H47 A;  1L6N A;  4U0D A;  1M9F C;  5HGM A;  1M9C C;  4QNB A;  1G03 A;  2LF4 A;  2X83 A;  4E91 A;  4U0B A;  1M9E C;  2PWO A;  1QRJ A;  2X82 A;  4PH0 A;  2XGY A;  1EM9 A;  1U7K A;  4PH3 A;  2M8N A;  2Y4Z A;  2PWM A;  5JPA A;  2PXR C;  2V4X A;  1AFV A;  4U0F A;  4XRO A;  1D1D A;  1M9X C;  2GON A;  5HGO A;  4XRQ A;  4DGE C;  2WLV A;  4XFY A;  4PH2 A;  4U0C A;  2XDE A;  1AK4 C;  4LQW C;  4U0A A;  2GOL B;  5HGN A;  1P7N A;  2JPR A;  4U0E A;  4J93 A;  5HGK A;  2XGV A;  3MGE A;  2XGU A;  1EIA A;  3BP9 A;  1E6J P; 
#chains in the Genus database with same CATH topology
 2EIA A;  2M8L A;  4E92 A;  4INB A;  4NX4 C;  2X2D D;  4HTW A;  4DGA C;  4XFZ A;  4B4N A;  1M9Y C;  4XFX A;  5HGL A;  3P05 A;  3H4E A;  4WYM A;  3NTE A;  2M8P A;  1M9D C;  2KGF A;  1GWP A;  2WLV B;  3H47 A;  1L6N A;  4U0D A;  1M9F C;  5HGM A;  1M9C C;  4QNB A;  1G03 A;  2LF4 A;  2X83 A;  4E91 A;  4U0B A;  1M9E C;  2PWO A;  1QRJ A;  2X82 A;  4PH0 A;  2XGY A;  1EM9 A;  1U7K A;  4PH3 A;  2M8N A;  2Y4Z A;  2PWM A;  5JPA A;  2PXR C;  2V4X A;  1AFV A;  4U0F A;  4XRO A;  1D1D A;  1M9X C;  2GON A;  5HGO A;  4XRQ A;  4DGE C;  2WLV A;  4XFY A;  4PH2 A;  4U0C A;  2XDE A;  1AK4 C;  4LQW C;  4U0A A;  2GOL B;  5HGN A;  1P7N A;  2JPR A;  4U0E A;  4J93 A;  5HGK A;  2XGV A;  3MGE A;  2XGU A;  1EIA A;  3BP9 A;  1E6J P; 
#chains in the Genus database with same CATH homology
 2EIA A;  2M8L A;  4E92 A;  4INB A;  4NX4 C;  2X2D D;  4HTW A;  4DGA C;  4XFZ A;  4B4N A;  1M9Y C;  4XFX A;  5HGL A;  3P05 A;  3H4E A;  4WYM A;  3NTE A;  2M8P A;  1M9D C;  2KGF A;  1GWP A;  2WLV B;  3H47 A;  1L6N A;  4U0D A;  1M9F C;  5HGM A;  1M9C C;  4QNB A;  1G03 A;  2LF4 A;  2X83 A;  4E91 A;  4U0B A;  1M9E C;  2PWO A;  1QRJ A;  2X82 A;  4PH0 A;  2XGY A;  1EM9 A;  1U7K A;  4PH3 A;  2M8N A;  2Y4Z A;  2PWM A;  5JPA A;  2PXR C;  2V4X A;  1AFV A;  4U0F A;  4XRO A;  1D1D A;  1M9X C;  2GON A;  5HGO A;  4XRQ A;  4DGE C;  2WLV A;  4XFY A;  4PH2 A;  4U0C A;  2XDE A;  1AK4 C;  4LQW C;  4U0A A;  2GOL B;  5HGN A;  1P7N A;  2JPR A;  4U0E A;  4J93 A;  5HGK A;  2XGV A;  3MGE A;  2XGU A;  1EIA A;  3BP9 A;  1E6J P; 
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similar chains in the pdb database (?% sequence similarity)

 
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