1M9CC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) m-type complex.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 49
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9cC00
1M9YC 4DGAC 4U0CA 3H4EA 4E91A 2M8PA 1P7NA 2V4XA 3MGEA 2X82A 3NTEA 1GWPA 4NX4C 4B4NA 5HGNA 3H47A 1M9DC 4PH3A 4XFZA 4J93A 1AK4C 2XGYA 4HTWA 4U0BA 2KGFA 2PWOA 2XDEA 2LF4A 1M9EC 2XGVA 4U0DA 4XFYA 1M9CC 4INBA 4WYMA 3P05A 2X83A 2M8NA 1D1DA 2GOLB 4PH0A 5HGKA 4XFXA 5JPAA 1M9FC 2JPRA 5HGLA 1QRJA 4LQWC 4XRQA 2PXRC 2WLVB 2PWMA 1E6JP 2Y4ZA 1G03A 1U7KA 3BP9A 2M8LA 2EIAA 1L6NA 5HGMA 1EM9A 1M9XC 5HGOA 4U0AA 4PH2A 2XGUA 4E92A 4QNBA 4XROA 1AFVA 2GONA 4U0EA 4U0FA 4DGEC 1EIAA 2WLVA 2X2DD
chains in the Genus database with same CATH superfamily
1M9YC 4DGAC 4U0CA 3H4EA 4E91A 2M8PA 1P7NA 2V4XA 3MGEA 2X82A 3NTEA 1GWPA 4NX4C 4B4NA 5HGNA 3H47A 1M9DC 4PH3A 4XFZA 4J93A 1AK4C 2XGYA 4HTWA 4U0BA 2KGFA 2PWOA 2XDEA 2LF4A 1M9EC 2XGVA 4U0DA 4XFYA 1M9CC 4INBA 4WYMA 3P05A 2X83A 2M8NA 1D1DA 2GOLB 4PH0A 5HGKA 4XFXA 5JPAA 1M9FC 2JPRA 5HGLA 1QRJA 4LQWC 4XRQA 2PXRC 2WLVB 2PWMA 1E6JP 2Y4ZA 1G03A 1U7KA 3BP9A 2M8LA 2EIAA 1L6NA 5HGMA 1EM9A 1M9XC 5HGOA 4U0AA 4PH2A 2XGUA 4E92A 4QNBA 4XROA 1AFVA 2GONA 4U0EA 4U0FA 4DGEC 1EIAA 2WLVA 2X2DD
chains in the Genus database with same CATH topology
1M9YC 4DGAC 4U0CA 3H4EA 4E91A 2M8PA 1P7NA 2V4XA 3MGEA 2X82A 3NTEA 1GWPA 4NX4C 4B4NA 5HGNA 3H47A 1M9DC 4PH3A 4XFZA 4J93A 1AK4C 2XGYA 4HTWA 4U0BA 2KGFA 2PWOA 2XDEA 2LF4A 1M9EC 2XGVA 4U0DA 4XFYA 1M9CC 4INBA 4WYMA 3P05A 2X83A 2M8NA 1D1DA 2GOLB 4PH0A 5HGKA 4XFXA 5JPAA 1M9FC 2JPRA 5HGLA 1QRJA 4LQWC 4XRQA 2PXRC 2WLVB 2PWMA 1E6JP 2Y4ZA 1G03A 1U7KA 3BP9A 2M8LA 2EIAA 1L6NA 5HGMA 1EM9A 1M9XC 5HGOA 4U0AA 4PH2A 2XGUA 4E92A 4QNBA 4XROA 1AFVA 2GONA 4U0EA 4U0FA 4DGEC 1EIAA 2WLVA 2X2DD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M9Y C;  4DGA C;  4U0C A;  3H4E A;  4E91 A;  2M8P A;  1P7N A;  2V4X A;  3MGE A;  2X82 A;  3NTE A;  1GWP A;  4NX4 C;  4B4N A;  5HGN A;  3H47 A;  1M9D C;  4PH3 A;  4XFZ A;  4J93 A;  1AK4 C;  2XGY A;  4HTW A;  4U0B A;  2KGF A;  2PWO A;  2XDE A;  2LF4 A;  1M9E C;  2XGV A;  4U0D A;  4XFY A;  1M9C C;  4INB A;  4WYM A;  3P05 A;  2X83 A;  2M8N A;  1D1D A;  2GOL B;  4PH0 A;  5HGK A;  4XFX A;  5JPA A;  1M9F C;  2JPR A;  5HGL A;  1QRJ A;  4LQW C;  4XRQ A;  2PXR C;  2WLV B;  2PWM A;  1E6J P;  2Y4Z A;  1G03 A;  1U7K A;  3BP9 A;  2M8L A;  2EIA A;  1L6N A;  5HGM A;  1EM9 A;  1M9X C;  5HGO A;  4U0A A;  4PH2 A;  2XGU A;  4E92 A;  4QNB A;  4XRO A;  1AFV A;  2GON A;  4U0E A;  4U0F A;  4DGE C;  1EIA A;  2WLV A;  2X2D D; 
#chains in the Genus database with same CATH topology
 1M9Y C;  4DGA C;  4U0C A;  3H4E A;  4E91 A;  2M8P A;  1P7N A;  2V4X A;  3MGE A;  2X82 A;  3NTE A;  1GWP A;  4NX4 C;  4B4N A;  5HGN A;  3H47 A;  1M9D C;  4PH3 A;  4XFZ A;  4J93 A;  1AK4 C;  2XGY A;  4HTW A;  4U0B A;  2KGF A;  2PWO A;  2XDE A;  2LF4 A;  1M9E C;  2XGV A;  4U0D A;  4XFY A;  1M9C C;  4INB A;  4WYM A;  3P05 A;  2X83 A;  2M8N A;  1D1D A;  2GOL B;  4PH0 A;  5HGK A;  4XFX A;  5JPA A;  1M9F C;  2JPR A;  5HGL A;  1QRJ A;  4LQW C;  4XRQ A;  2PXR C;  2WLV B;  2PWM A;  1E6J P;  2Y4Z A;  1G03 A;  1U7K A;  3BP9 A;  2M8L A;  2EIA A;  1L6N A;  5HGM A;  1EM9 A;  1M9X C;  5HGO A;  4U0A A;  4PH2 A;  2XGU A;  4E92 A;  4QNB A;  4XRO A;  1AFV A;  2GON A;  4U0E A;  4U0F A;  4DGE C;  1EIA A;  2WLV A;  2X2D D; 
#chains in the Genus database with same CATH homology
 1M9Y C;  4DGA C;  4U0C A;  3H4E A;  4E91 A;  2M8P A;  1P7N A;  2V4X A;  3MGE A;  2X82 A;  3NTE A;  1GWP A;  4NX4 C;  4B4N A;  5HGN A;  3H47 A;  1M9D C;  4PH3 A;  4XFZ A;  4J93 A;  1AK4 C;  2XGY A;  4HTW A;  4U0B A;  2KGF A;  2PWO A;  2XDE A;  2LF4 A;  1M9E C;  2XGV A;  4U0D A;  4XFY A;  1M9C C;  4INB A;  4WYM A;  3P05 A;  2X83 A;  2M8N A;  1D1D A;  2GOL B;  4PH0 A;  5HGK A;  4XFX A;  5JPA A;  1M9F C;  2JPR A;  5HGL A;  1QRJ A;  4LQW C;  4XRQ A;  2PXR C;  2WLV B;  2PWM A;  1E6J P;  2Y4Z A;  1G03 A;  1U7K A;  3BP9 A;  2M8L A;  2EIA A;  1L6N A;  5HGM A;  1EM9 A;  1M9X C;  5HGO A;  4U0A A;  4PH2 A;  2XGU A;  4E92 A;  4QNB A;  4XRO A;  1AFV A;  2GON A;  4U0E A;  4U0F A;  4DGE C;  1EIA A;  2WLV A;  2X2D D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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