1M9DC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) o-type chimera complex.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 49
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9dC00
4E92A 2PWMA 2X82A 2Y4ZA 2WLVA 4XROA 4DGAC 3MGEA 2X2DD 1M9EC 2M8NA 5HGLA 2JPRA 2LF4A 2XDEA 4DGEC 5HGOA 1P7NA 1G03A 4XFYA 2XGUA 2XGYA 4U0DA 4INBA 1M9CC 4HTWA 2PXRC 4NX4C 1D1DA 4B4NA 1M9YC 4XFXA 3BP9A 4LQWC 5JPAA 4QNBA 4XFZA 1QRJA 2GONA 1AFVA 4PH3A 2X83A 4U0BA 2EIAA 4WYMA 4U0CA 1EM9A 5HGNA 1U7KA 3H4EA 1AK4C 1GWPA 2M8LA 1L6NA 3H47A 2PWOA 4E91A 4PH0A 1M9DC 4PH2A 1M9FC 4XRQA 1EIAA 1E6JP 2V4XA 2WLVB 2M8PA 4U0FA 4J93A 3NTEA 2KGFA 2GOLB 4U0AA 2XGVA 5HGMA 4U0EA 1M9XC 3P05A 5HGKA
chains in the Genus database with same CATH superfamily
4E92A 2PWMA 2X82A 2Y4ZA 2WLVA 4XROA 4DGAC 3MGEA 2X2DD 1M9EC 2M8NA 5HGLA 2JPRA 2LF4A 2XDEA 4DGEC 5HGOA 1P7NA 1G03A 4XFYA 2XGUA 2XGYA 4U0DA 4INBA 1M9CC 4HTWA 2PXRC 4NX4C 1D1DA 4B4NA 1M9YC 4XFXA 3BP9A 4LQWC 5JPAA 4QNBA 4XFZA 1QRJA 2GONA 1AFVA 4PH3A 2X83A 4U0BA 2EIAA 4WYMA 4U0CA 1EM9A 5HGNA 1U7KA 3H4EA 1AK4C 1GWPA 2M8LA 1L6NA 3H47A 2PWOA 4E91A 4PH0A 1M9DC 4PH2A 1M9FC 4XRQA 1EIAA 1E6JP 2V4XA 2WLVB 2M8PA 4U0FA 4J93A 3NTEA 2KGFA 2GOLB 4U0AA 2XGVA 5HGMA 4U0EA 1M9XC 3P05A 5HGKA
chains in the Genus database with same CATH topology
4E92A 2PWMA 2X82A 2Y4ZA 2WLVA 4XROA 4DGAC 3MGEA 2X2DD 1M9EC 2M8NA 5HGLA 2JPRA 2LF4A 2XDEA 4DGEC 5HGOA 1P7NA 1G03A 4XFYA 2XGUA 2XGYA 4U0DA 4INBA 1M9CC 4HTWA 2PXRC 4NX4C 1D1DA 4B4NA 1M9YC 4XFXA 3BP9A 4LQWC 5JPAA 4QNBA 4XFZA 1QRJA 2GONA 1AFVA 4PH3A 2X83A 4U0BA 2EIAA 4WYMA 4U0CA 1EM9A 5HGNA 1U7KA 3H4EA 1AK4C 1GWPA 2M8LA 1L6NA 3H47A 2PWOA 4E91A 4PH0A 1M9DC 4PH2A 1M9FC 4XRQA 1EIAA 1E6JP 2V4XA 2WLVB 2M8PA 4U0FA 4J93A 3NTEA 2KGFA 2GOLB 4U0AA 2XGVA 5HGMA 4U0EA 1M9XC 3P05A 5HGKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E92 A;  2PWM A;  2X82 A;  2Y4Z A;  2WLV A;  4XRO A;  4DGA C;  3MGE A;  2X2D D;  1M9E C;  2M8N A;  5HGL A;  2JPR A;  2LF4 A;  2XDE A;  4DGE C;  5HGO A;  1P7N A;  1G03 A;  4XFY A;  2XGU A;  2XGY A;  4U0D A;  4INB A;  1M9C C;  4HTW A;  2PXR C;  4NX4 C;  1D1D A;  4B4N A;  1M9Y C;  4XFX A;  3BP9 A;  4LQW C;  5JPA A;  4QNB A;  4XFZ A;  1QRJ A;  2GON A;  1AFV A;  4PH3 A;  2X83 A;  4U0B A;  2EIA A;  4WYM A;  4U0C A;  1EM9 A;  5HGN A;  1U7K A;  3H4E A;  1AK4 C;  1GWP A;  2M8L A;  1L6N A;  3H47 A;  2PWO A;  4E91 A;  4PH0 A;  1M9D C;  4PH2 A;  1M9F C;  4XRQ A;  1EIA A;  1E6J P;  2V4X A;  2WLV B;  2M8P A;  4U0F A;  4J93 A;  3NTE A;  2KGF A;  2GOL B;  4U0A A;  2XGV A;  5HGM A;  4U0E A;  1M9X C;  3P05 A;  5HGK A; 
#chains in the Genus database with same CATH topology
 4E92 A;  2PWM A;  2X82 A;  2Y4Z A;  2WLV A;  4XRO A;  4DGA C;  3MGE A;  2X2D D;  1M9E C;  2M8N A;  5HGL A;  2JPR A;  2LF4 A;  2XDE A;  4DGE C;  5HGO A;  1P7N A;  1G03 A;  4XFY A;  2XGU A;  2XGY A;  4U0D A;  4INB A;  1M9C C;  4HTW A;  2PXR C;  4NX4 C;  1D1D A;  4B4N A;  1M9Y C;  4XFX A;  3BP9 A;  4LQW C;  5JPA A;  4QNB A;  4XFZ A;  1QRJ A;  2GON A;  1AFV A;  4PH3 A;  2X83 A;  4U0B A;  2EIA A;  4WYM A;  4U0C A;  1EM9 A;  5HGN A;  1U7K A;  3H4E A;  1AK4 C;  1GWP A;  2M8L A;  1L6N A;  3H47 A;  2PWO A;  4E91 A;  4PH0 A;  1M9D C;  4PH2 A;  1M9F C;  4XRQ A;  1EIA A;  1E6J P;  2V4X A;  2WLV B;  2M8P A;  4U0F A;  4J93 A;  3NTE A;  2KGF A;  2GOL B;  4U0A A;  2XGV A;  5HGM A;  4U0E A;  1M9X C;  3P05 A;  5HGK A; 
#chains in the Genus database with same CATH homology
 4E92 A;  2PWM A;  2X82 A;  2Y4Z A;  2WLV A;  4XRO A;  4DGA C;  3MGE A;  2X2D D;  1M9E C;  2M8N A;  5HGL A;  2JPR A;  2LF4 A;  2XDE A;  4DGE C;  5HGO A;  1P7N A;  1G03 A;  4XFY A;  2XGU A;  2XGY A;  4U0D A;  4INB A;  1M9C C;  4HTW A;  2PXR C;  4NX4 C;  1D1D A;  4B4N A;  1M9Y C;  4XFX A;  3BP9 A;  4LQW C;  5JPA A;  4QNB A;  4XFZ A;  1QRJ A;  2GON A;  1AFV A;  4PH3 A;  2X83 A;  4U0B A;  2EIA A;  4WYM A;  4U0C A;  1EM9 A;  5HGN A;  1U7K A;  3H4E A;  1AK4 C;  1GWP A;  2M8L A;  1L6N A;  3H47 A;  2PWO A;  4E91 A;  4PH0 A;  1M9D C;  4PH2 A;  1M9F C;  4XRQ A;  1EIA A;  1E6J P;  2V4X A;  2WLV B;  2M8P A;  4U0F A;  4J93 A;  3NTE A;  2KGF A;  2GOL B;  4U0A A;  2XGV A;  5HGM A;  4U0E A;  1M9X C;  3P05 A;  5HGK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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