1M9FC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) m-type h87a,a88m complex.
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVAMGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 50
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9fC00
2X82A 1L6NA 1M9YC 2XGUA 3NTEA 2JPRA 1M9DC 2XGYA 2M8PA 4J93A 4U0FA 4NX4C 4DGAC 4LQWC 1G03A 1AK4C 1M9CC 5HGMA 4U0BA 4WYMA 3H47A 2V4XA 4DGEC 2GONA 2WLVA 4XROA 2WLVB 1AFVA 2PWMA 4B4NA 4QNBA 4PH0A 2XGVA 3P05A 2Y4ZA 1E6JP 3BP9A 5HGOA 4HTWA 2PXRC 4E92A 4U0AA 5HGKA 2M8NA 4XFZA 4INBA 2M8LA 4U0CA 4E91A 1P7NA 2LF4A 2PWOA 2GOLB 4XFXA 1GWPA 4XFYA 5HGNA 5JPAA 4U0EA 1EIAA 1EM9A 2EIAA 5HGLA 2KGFA 4PH3A 4PH2A 2X2DD 1QRJA 1D1DA 4U0DA 1M9EC 2X83A 1U7KA 3MGEA 1M9FC 4XRQA 1M9XC 2XDEA 3H4EA
chains in the Genus database with same CATH superfamily
2X82A 1L6NA 1M9YC 2XGUA 3NTEA 2JPRA 1M9DC 2XGYA 2M8PA 4J93A 4U0FA 4NX4C 4DGAC 4LQWC 1G03A 1AK4C 1M9CC 5HGMA 4U0BA 4WYMA 3H47A 2V4XA 4DGEC 2GONA 2WLVA 4XROA 2WLVB 1AFVA 2PWMA 4B4NA 4QNBA 4PH0A 2XGVA 3P05A 2Y4ZA 1E6JP 3BP9A 5HGOA 4HTWA 2PXRC 4E92A 4U0AA 5HGKA 2M8NA 4XFZA 4INBA 2M8LA 4U0CA 4E91A 1P7NA 2LF4A 2PWOA 2GOLB 4XFXA 1GWPA 4XFYA 5HGNA 5JPAA 4U0EA 1EIAA 1EM9A 2EIAA 5HGLA 2KGFA 4PH3A 4PH2A 2X2DD 1QRJA 1D1DA 4U0DA 1M9EC 2X83A 1U7KA 3MGEA 1M9FC 4XRQA 1M9XC 2XDEA 3H4EA
chains in the Genus database with same CATH topology
2X82A 1L6NA 1M9YC 2XGUA 3NTEA 2JPRA 1M9DC 2XGYA 2M8PA 4J93A 4U0FA 4NX4C 4DGAC 4LQWC 1G03A 1AK4C 1M9CC 5HGMA 4U0BA 4WYMA 3H47A 2V4XA 4DGEC 2GONA 2WLVA 4XROA 2WLVB 1AFVA 2PWMA 4B4NA 4QNBA 4PH0A 2XGVA 3P05A 2Y4ZA 1E6JP 3BP9A 5HGOA 4HTWA 2PXRC 4E92A 4U0AA 5HGKA 2M8NA 4XFZA 4INBA 2M8LA 4U0CA 4E91A 1P7NA 2LF4A 2PWOA 2GOLB 4XFXA 1GWPA 4XFYA 5HGNA 5JPAA 4U0EA 1EIAA 1EM9A 2EIAA 5HGLA 2KGFA 4PH3A 4PH2A 2X2DD 1QRJA 1D1DA 4U0DA 1M9EC 2X83A 1U7KA 3MGEA 1M9FC 4XRQA 1M9XC 2XDEA 3H4EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X82 A;  1L6N A;  1M9Y C;  2XGU A;  3NTE A;  2JPR A;  1M9D C;  2XGY A;  2M8P A;  4J93 A;  4U0F A;  4NX4 C;  4DGA C;  4LQW C;  1G03 A;  1AK4 C;  1M9C C;  5HGM A;  4U0B A;  4WYM A;  3H47 A;  2V4X A;  4DGE C;  2GON A;  2WLV A;  4XRO A;  2WLV B;  1AFV A;  2PWM A;  4B4N A;  4QNB A;  4PH0 A;  2XGV A;  3P05 A;  2Y4Z A;  1E6J P;  3BP9 A;  5HGO A;  4HTW A;  2PXR C;  4E92 A;  4U0A A;  5HGK A;  2M8N A;  4XFZ A;  4INB A;  2M8L A;  4U0C A;  4E91 A;  1P7N A;  2LF4 A;  2PWO A;  2GOL B;  4XFX A;  1GWP A;  4XFY A;  5HGN A;  5JPA A;  4U0E A;  1EIA A;  1EM9 A;  2EIA A;  5HGL A;  2KGF A;  4PH3 A;  4PH2 A;  2X2D D;  1QRJ A;  1D1D A;  4U0D A;  1M9E C;  2X83 A;  1U7K A;  3MGE A;  1M9F C;  4XRQ A;  1M9X C;  2XDE A;  3H4E A; 
#chains in the Genus database with same CATH topology
 2X82 A;  1L6N A;  1M9Y C;  2XGU A;  3NTE A;  2JPR A;  1M9D C;  2XGY A;  2M8P A;  4J93 A;  4U0F A;  4NX4 C;  4DGA C;  4LQW C;  1G03 A;  1AK4 C;  1M9C C;  5HGM A;  4U0B A;  4WYM A;  3H47 A;  2V4X A;  4DGE C;  2GON A;  2WLV A;  4XRO A;  2WLV B;  1AFV A;  2PWM A;  4B4N A;  4QNB A;  4PH0 A;  2XGV A;  3P05 A;  2Y4Z A;  1E6J P;  3BP9 A;  5HGO A;  4HTW A;  2PXR C;  4E92 A;  4U0A A;  5HGK A;  2M8N A;  4XFZ A;  4INB A;  2M8L A;  4U0C A;  4E91 A;  1P7N A;  2LF4 A;  2PWO A;  2GOL B;  4XFX A;  1GWP A;  4XFY A;  5HGN A;  5JPA A;  4U0E A;  1EIA A;  1EM9 A;  2EIA A;  5HGL A;  2KGF A;  4PH3 A;  4PH2 A;  2X2D D;  1QRJ A;  1D1D A;  4U0D A;  1M9E C;  2X83 A;  1U7K A;  3MGE A;  1M9F C;  4XRQ A;  1M9X C;  2XDE A;  3H4E A; 
#chains in the Genus database with same CATH homology
 2X82 A;  1L6N A;  1M9Y C;  2XGU A;  3NTE A;  2JPR A;  1M9D C;  2XGY A;  2M8P A;  4J93 A;  4U0F A;  4NX4 C;  4DGA C;  4LQW C;  1G03 A;  1AK4 C;  1M9C C;  5HGM A;  4U0B A;  4WYM A;  3H47 A;  2V4X A;  4DGE C;  2GON A;  2WLV A;  4XRO A;  2WLV B;  1AFV A;  2PWM A;  4B4N A;  4QNB A;  4PH0 A;  2XGV A;  3P05 A;  2Y4Z A;  1E6J P;  3BP9 A;  5HGO A;  4HTW A;  2PXR C;  4E92 A;  4U0A A;  5HGK A;  2M8N A;  4XFZ A;  4INB A;  2M8L A;  4U0C A;  4E91 A;  1P7N A;  2LF4 A;  2PWO A;  2GOL B;  4XFX A;  1GWP A;  4XFY A;  5HGN A;  5JPA A;  4U0E A;  1EIA A;  1EM9 A;  2EIA A;  5HGL A;  2KGF A;  4PH3 A;  4PH2 A;  2X2D D;  1QRJ A;  1D1D A;  4U0D A;  1M9E C;  2X83 A;  1U7K A;  3MGE A;  1M9F C;  4XRQ A;  1M9X C;  2XDE A;  3H4E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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