1M9FC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) m-type h87a,a88m complex.
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVAMGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 50
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9fC00
2XGYA 5HGLA 2M8LA 3H47A 4U0CA 4U0BA 2XDEA 4U0AA 2X82A 5HGMA 4XFXA 1AFVA 4NX4C 1AK4C 1GWPA 2X2DD 1M9XC 4E91A 2LF4A 3NTEA 4WYMA 1M9EC 3P05A 1M9FC 1P7NA 4QNBA 1E6JP 5HGOA 2EIAA 4B4NA 1M9DC 1EM9A 1M9CC 5HGNA 2GONA 3H4EA 4PH3A 4PH0A 3MGEA 2M8NA 1EIAA 2PXRC 4XRQA 2Y4ZA 4XFZA 2PWOA 2JPRA 2XGVA 4LQWC 3BP9A 4DGEC 2WLVB 4U0EA 1G03A 4HTWA 5JPAA 4E92A 5HGKA 4U0FA 2PWMA 1D1DA 4PH2A 1M9YC 2KGFA 1QRJA 4XROA 2X83A 2V4XA 4DGAC 2WLVA 1L6NA 1U7KA 4INBA 2XGUA 4U0DA 2GOLB 4XFYA 4J93A 2M8PA
chains in the Genus database with same CATH superfamily
2XGYA 5HGLA 2M8LA 3H47A 4U0CA 4U0BA 2XDEA 4U0AA 2X82A 5HGMA 4XFXA 1AFVA 4NX4C 1AK4C 1GWPA 2X2DD 1M9XC 4E91A 2LF4A 3NTEA 4WYMA 1M9EC 3P05A 1M9FC 1P7NA 4QNBA 1E6JP 5HGOA 2EIAA 4B4NA 1M9DC 1EM9A 1M9CC 5HGNA 2GONA 3H4EA 4PH3A 4PH0A 3MGEA 2M8NA 1EIAA 2PXRC 4XRQA 2Y4ZA 4XFZA 2PWOA 2JPRA 2XGVA 4LQWC 3BP9A 4DGEC 2WLVB 4U0EA 1G03A 4HTWA 5JPAA 4E92A 5HGKA 4U0FA 2PWMA 1D1DA 4PH2A 1M9YC 2KGFA 1QRJA 4XROA 2X83A 2V4XA 4DGAC 2WLVA 1L6NA 1U7KA 4INBA 2XGUA 4U0DA 2GOLB 4XFYA 4J93A 2M8PA
chains in the Genus database with same CATH topology
2XGYA 5HGLA 2M8LA 3H47A 4U0CA 4U0BA 2XDEA 4U0AA 2X82A 5HGMA 4XFXA 1AFVA 4NX4C 1AK4C 1GWPA 2X2DD 1M9XC 4E91A 2LF4A 3NTEA 4WYMA 1M9EC 3P05A 1M9FC 1P7NA 4QNBA 1E6JP 5HGOA 2EIAA 4B4NA 1M9DC 1EM9A 1M9CC 5HGNA 2GONA 3H4EA 4PH3A 4PH0A 3MGEA 2M8NA 1EIAA 2PXRC 4XRQA 2Y4ZA 4XFZA 2PWOA 2JPRA 2XGVA 4LQWC 3BP9A 4DGEC 2WLVB 4U0EA 1G03A 4HTWA 5JPAA 4E92A 5HGKA 4U0FA 2PWMA 1D1DA 4PH2A 1M9YC 2KGFA 1QRJA 4XROA 2X83A 2V4XA 4DGAC 2WLVA 1L6NA 1U7KA 4INBA 2XGUA 4U0DA 2GOLB 4XFYA 4J93A 2M8PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XGY A;  5HGL A;  2M8L A;  3H47 A;  4U0C A;  4U0B A;  2XDE A;  4U0A A;  2X82 A;  5HGM A;  4XFX A;  1AFV A;  4NX4 C;  1AK4 C;  1GWP A;  2X2D D;  1M9X C;  4E91 A;  2LF4 A;  3NTE A;  4WYM A;  1M9E C;  3P05 A;  1M9F C;  1P7N A;  4QNB A;  1E6J P;  5HGO A;  2EIA A;  4B4N A;  1M9D C;  1EM9 A;  1M9C C;  5HGN A;  2GON A;  3H4E A;  4PH3 A;  4PH0 A;  3MGE A;  2M8N A;  1EIA A;  2PXR C;  4XRQ A;  2Y4Z A;  4XFZ A;  2PWO A;  2JPR A;  2XGV A;  4LQW C;  3BP9 A;  4DGE C;  2WLV B;  4U0E A;  1G03 A;  4HTW A;  5JPA A;  4E92 A;  5HGK A;  4U0F A;  2PWM A;  1D1D A;  4PH2 A;  1M9Y C;  2KGF A;  1QRJ A;  4XRO A;  2X83 A;  2V4X A;  4DGA C;  2WLV A;  1L6N A;  1U7K A;  4INB A;  2XGU A;  4U0D A;  2GOL B;  4XFY A;  4J93 A;  2M8P A; 
#chains in the Genus database with same CATH topology
 2XGY A;  5HGL A;  2M8L A;  3H47 A;  4U0C A;  4U0B A;  2XDE A;  4U0A A;  2X82 A;  5HGM A;  4XFX A;  1AFV A;  4NX4 C;  1AK4 C;  1GWP A;  2X2D D;  1M9X C;  4E91 A;  2LF4 A;  3NTE A;  4WYM A;  1M9E C;  3P05 A;  1M9F C;  1P7N A;  4QNB A;  1E6J P;  5HGO A;  2EIA A;  4B4N A;  1M9D C;  1EM9 A;  1M9C C;  5HGN A;  2GON A;  3H4E A;  4PH3 A;  4PH0 A;  3MGE A;  2M8N A;  1EIA A;  2PXR C;  4XRQ A;  2Y4Z A;  4XFZ A;  2PWO A;  2JPR A;  2XGV A;  4LQW C;  3BP9 A;  4DGE C;  2WLV B;  4U0E A;  1G03 A;  4HTW A;  5JPA A;  4E92 A;  5HGK A;  4U0F A;  2PWM A;  1D1D A;  4PH2 A;  1M9Y C;  2KGF A;  1QRJ A;  4XRO A;  2X83 A;  2V4X A;  4DGA C;  2WLV A;  1L6N A;  1U7K A;  4INB A;  2XGU A;  4U0D A;  2GOL B;  4XFY A;  4J93 A;  2M8P A; 
#chains in the Genus database with same CATH homology
 2XGY A;  5HGL A;  2M8L A;  3H47 A;  4U0C A;  4U0B A;  2XDE A;  4U0A A;  2X82 A;  5HGM A;  4XFX A;  1AFV A;  4NX4 C;  1AK4 C;  1GWP A;  2X2D D;  1M9X C;  4E91 A;  2LF4 A;  3NTE A;  4WYM A;  1M9E C;  3P05 A;  1M9F C;  1P7N A;  4QNB A;  1E6J P;  5HGO A;  2EIA A;  4B4N A;  1M9D C;  1EM9 A;  1M9C C;  5HGN A;  2GON A;  3H4E A;  4PH3 A;  4PH0 A;  3MGE A;  2M8N A;  1EIA A;  2PXR C;  4XRQ A;  2Y4Z A;  4XFZ A;  2PWO A;  2JPR A;  2XGV A;  4LQW C;  3BP9 A;  4DGE C;  2WLV B;  4U0E A;  1G03 A;  4HTW A;  5JPA A;  4E92 A;  5HGK A;  4U0F A;  2PWM A;  1D1D A;  4PH2 A;  1M9Y C;  2KGF A;  1QRJ A;  4XRO A;  2X83 A;  2V4X A;  4DGA C;  2WLV A;  1L6N A;  1U7K A;  4INB A;  2XGU A;  4U0D A;  2GOL B;  4XFY A;  4J93 A;  2M8P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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