1M9YC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) m-type h87a,g89a complex.
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVAAAPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 48
structure length 146
sequence length 146
chains with identical sequence D, G, H
ec nomenclature
pdb deposition date 2002-07-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9yC00
4HTWA 4INBA 2LF4A 1G03A 2V4XA 1M9CC 3BP9A 2X82A 1D1DA 3H4EA 3P05A 1AFVA 1E6JP 4QNBA 2WLVB 5HGMA 4XFXA 4U0CA 4XRQA 1M9DC 2XDEA 2GONA 1AK4C 5HGOA 3MGEA 4U0DA 1QRJA 1U7KA 1L6NA 2M8LA 4U0EA 2PXRC 2M8NA 2XGUA 2JPRA 1M9XC 1EIAA 4E92A 2Y4ZA 4J93A 4PH3A 4U0AA 5HGLA 2X2DD 4PH2A 4LQWC 4B4NA 4XROA 2M8PA 2KGFA 4U0BA 2XGYA 2WLVA 1GWPA 2XGVA 1M9EC 4U0FA 2PWMA 1M9YC 1EM9A 4E91A 4PH0A 4XFYA 4DGEC 2PWOA 4WYMA 5JPAA 5HGNA 2GOLB 3NTEA 2EIAA 1M9FC 1P7NA 4NX4C 4XFZA 5HGKA 2X83A 3H47A 4DGAC
chains in the Genus database with same CATH superfamily
4HTWA 4INBA 2LF4A 1G03A 2V4XA 1M9CC 3BP9A 2X82A 1D1DA 3H4EA 3P05A 1AFVA 1E6JP 4QNBA 2WLVB 5HGMA 4XFXA 4U0CA 4XRQA 1M9DC 2XDEA 2GONA 1AK4C 5HGOA 3MGEA 4U0DA 1QRJA 1U7KA 1L6NA 2M8LA 4U0EA 2PXRC 2M8NA 2XGUA 2JPRA 1M9XC 1EIAA 4E92A 2Y4ZA 4J93A 4PH3A 4U0AA 5HGLA 2X2DD 4PH2A 4LQWC 4B4NA 4XROA 2M8PA 2KGFA 4U0BA 2XGYA 2WLVA 1GWPA 2XGVA 1M9EC 4U0FA 2PWMA 1M9YC 1EM9A 4E91A 4PH0A 4XFYA 4DGEC 2PWOA 4WYMA 5JPAA 5HGNA 2GOLB 3NTEA 2EIAA 1M9FC 1P7NA 4NX4C 4XFZA 5HGKA 2X83A 3H47A 4DGAC
chains in the Genus database with same CATH topology
4HTWA 4INBA 2LF4A 1G03A 2V4XA 1M9CC 3BP9A 2X82A 1D1DA 3H4EA 3P05A 1AFVA 1E6JP 4QNBA 2WLVB 5HGMA 4XFXA 4U0CA 4XRQA 1M9DC 2XDEA 2GONA 1AK4C 5HGOA 3MGEA 4U0DA 1QRJA 1U7KA 1L6NA 2M8LA 4U0EA 2PXRC 2M8NA 2XGUA 2JPRA 1M9XC 1EIAA 4E92A 2Y4ZA 4J93A 4PH3A 4U0AA 5HGLA 2X2DD 4PH2A 4LQWC 4B4NA 4XROA 2M8PA 2KGFA 4U0BA 2XGYA 2WLVA 1GWPA 2XGVA 1M9EC 4U0FA 2PWMA 1M9YC 1EM9A 4E91A 4PH0A 4XFYA 4DGEC 2PWOA 4WYMA 5JPAA 5HGNA 2GOLB 3NTEA 2EIAA 1M9FC 1P7NA 4NX4C 4XFZA 5HGKA 2X83A 3H47A 4DGAC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HTW A;  4INB A;  2LF4 A;  1G03 A;  2V4X A;  1M9C C;  3BP9 A;  2X82 A;  1D1D A;  3H4E A;  3P05 A;  1AFV A;  1E6J P;  4QNB A;  2WLV B;  5HGM A;  4XFX A;  4U0C A;  4XRQ A;  1M9D C;  2XDE A;  2GON A;  1AK4 C;  5HGO A;  3MGE A;  4U0D A;  1QRJ A;  1U7K A;  1L6N A;  2M8L A;  4U0E A;  2PXR C;  2M8N A;  2XGU A;  2JPR A;  1M9X C;  1EIA A;  4E92 A;  2Y4Z A;  4J93 A;  4PH3 A;  4U0A A;  5HGL A;  2X2D D;  4PH2 A;  4LQW C;  4B4N A;  4XRO A;  2M8P A;  2KGF A;  4U0B A;  2XGY A;  2WLV A;  1GWP A;  2XGV A;  1M9E C;  4U0F A;  2PWM A;  1M9Y C;  1EM9 A;  4E91 A;  4PH0 A;  4XFY A;  4DGE C;  2PWO A;  4WYM A;  5JPA A;  5HGN A;  2GOL B;  3NTE A;  2EIA A;  1M9F C;  1P7N A;  4NX4 C;  4XFZ A;  5HGK A;  2X83 A;  3H47 A;  4DGA C; 
#chains in the Genus database with same CATH topology
 4HTW A;  4INB A;  2LF4 A;  1G03 A;  2V4X A;  1M9C C;  3BP9 A;  2X82 A;  1D1D A;  3H4E A;  3P05 A;  1AFV A;  1E6J P;  4QNB A;  2WLV B;  5HGM A;  4XFX A;  4U0C A;  4XRQ A;  1M9D C;  2XDE A;  2GON A;  1AK4 C;  5HGO A;  3MGE A;  4U0D A;  1QRJ A;  1U7K A;  1L6N A;  2M8L A;  4U0E A;  2PXR C;  2M8N A;  2XGU A;  2JPR A;  1M9X C;  1EIA A;  4E92 A;  2Y4Z A;  4J93 A;  4PH3 A;  4U0A A;  5HGL A;  2X2D D;  4PH2 A;  4LQW C;  4B4N A;  4XRO A;  2M8P A;  2KGF A;  4U0B A;  2XGY A;  2WLV A;  1GWP A;  2XGV A;  1M9E C;  4U0F A;  2PWM A;  1M9Y C;  1EM9 A;  4E91 A;  4PH0 A;  4XFY A;  4DGE C;  2PWO A;  4WYM A;  5JPA A;  5HGN A;  2GOL B;  3NTE A;  2EIA A;  1M9F C;  1P7N A;  4NX4 C;  4XFZ A;  5HGK A;  2X83 A;  3H47 A;  4DGA C; 
#chains in the Genus database with same CATH homology
 4HTW A;  4INB A;  2LF4 A;  1G03 A;  2V4X A;  1M9C C;  3BP9 A;  2X82 A;  1D1D A;  3H4E A;  3P05 A;  1AFV A;  1E6J P;  4QNB A;  2WLV B;  5HGM A;  4XFX A;  4U0C A;  4XRQ A;  1M9D C;  2XDE A;  2GON A;  1AK4 C;  5HGO A;  3MGE A;  4U0D A;  1QRJ A;  1U7K A;  1L6N A;  2M8L A;  4U0E A;  2PXR C;  2M8N A;  2XGU A;  2JPR A;  1M9X C;  1EIA A;  4E92 A;  2Y4Z A;  4J93 A;  4PH3 A;  4U0A A;  5HGL A;  2X2D D;  4PH2 A;  4LQW C;  4B4N A;  4XRO A;  2M8P A;  2KGF A;  4U0B A;  2XGY A;  2WLV A;  1GWP A;  2XGV A;  1M9E C;  4U0F A;  2PWM A;  1M9Y C;  1EM9 A;  4E91 A;  4PH0 A;  4XFY A;  4DGE C;  2PWO A;  4WYM A;  5JPA A;  5HGN A;  2GOL B;  3NTE A;  2EIA A;  1M9F C;  1P7N A;  4NX4 C;  4XFZ A;  5HGK A;  2X83 A;  3H47 A;  4DGA C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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