1M9DC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) o-type chimera complex.
Total Genus 49
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 49
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9dC00
2M8LA 5HGOA 2X82A 4DGAC 3MGEA 1EM9A 1AFVA 1QRJA 1L6NA 1E6JP 2WLVA 2V4XA 1GWPA 1M9XC 1M9DC 2WLVB 4U0CA 2XGUA 4INBA 1M9CC 1M9FC 4PH0A 5JPAA 2M8NA 2XDEA 1AK4C 4XFXA 4QNBA 1M9YC 2PWMA 2KGFA 4J93A 4PH2A 3H4EA 4PH3A 5HGLA 2XGVA 4U0BA 4XFYA 1D1DA 2JPRA 3BP9A 4E92A 4XFZA 1P7NA 4LQWC 1M9EC 4U0EA 4WYMA 5HGKA 1EIAA 4U0FA 4XRQA 2XGYA 2PWOA 3NTEA 4NX4C 2PXRC 2EIAA 1U7KA 3P05A 2GONA 4U0AA 4DGEC 2M8PA 1G03A 4HTWA 5HGNA 2GOLB 4U0DA 4XROA 2LF4A 2X2DD 3H47A 2Y4ZA 5HGMA 4B4NA 2X83A 4E91A
chains in the Genus database with same CATH superfamily
2M8LA 5HGOA 2X82A 4DGAC 3MGEA 1EM9A 1AFVA 1QRJA 1L6NA 1E6JP 2WLVA 2V4XA 1GWPA 1M9XC 1M9DC 2WLVB 4U0CA 2XGUA 4INBA 1M9CC 1M9FC 4PH0A 5JPAA 2M8NA 2XDEA 1AK4C 4XFXA 4QNBA 1M9YC 2PWMA 2KGFA 4J93A 4PH2A 3H4EA 4PH3A 5HGLA 2XGVA 4U0BA 4XFYA 1D1DA 2JPRA 3BP9A 4E92A 4XFZA 1P7NA 4LQWC 1M9EC 4U0EA 4WYMA 5HGKA 1EIAA 4U0FA 4XRQA 2XGYA 2PWOA 3NTEA 4NX4C 2PXRC 2EIAA 1U7KA 3P05A 2GONA 4U0AA 4DGEC 2M8PA 1G03A 4HTWA 5HGNA 2GOLB 4U0DA 4XROA 2LF4A 2X2DD 3H47A 2Y4ZA 5HGMA 4B4NA 2X83A 4E91A
chains in the Genus database with same CATH topology
2M8LA 5HGOA 2X82A 4DGAC 3MGEA 1EM9A 1AFVA 1QRJA 1L6NA 1E6JP 2WLVA 2V4XA 1GWPA 1M9XC 1M9DC 2WLVB 4U0CA 2XGUA 4INBA 1M9CC 1M9FC 4PH0A 5JPAA 2M8NA 2XDEA 1AK4C 4XFXA 4QNBA 1M9YC 2PWMA 2KGFA 4J93A 4PH2A 3H4EA 4PH3A 5HGLA 2XGVA 4U0BA 4XFYA 1D1DA 2JPRA 3BP9A 4E92A 4XFZA 1P7NA 4LQWC 1M9EC 4U0EA 4WYMA 5HGKA 1EIAA 4U0FA 4XRQA 2XGYA 2PWOA 3NTEA 4NX4C 2PXRC 2EIAA 1U7KA 3P05A 2GONA 4U0AA 4DGEC 2M8PA 1G03A 4HTWA 5HGNA 2GOLB 4U0DA 4XROA 2LF4A 2X2DD 3H47A 2Y4ZA 5HGMA 4B4NA 2X83A 4E91A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2M8L A;  5HGO A;  2X82 A;  4DGA C;  3MGE A;  1EM9 A;  1AFV A;  1QRJ A;  1L6N A;  1E6J P;  2WLV A;  2V4X A;  1GWP A;  1M9X C;  1M9D C;  2WLV B;  4U0C A;  2XGU A;  4INB A;  1M9C C;  1M9F C;  4PH0 A;  5JPA A;  2M8N A;  2XDE A;  1AK4 C;  4XFX A;  4QNB A;  1M9Y C;  2PWM A;  2KGF A;  4J93 A;  4PH2 A;  3H4E A;  4PH3 A;  5HGL A;  2XGV A;  4U0B A;  4XFY A;  1D1D A;  2JPR A;  3BP9 A;  4E92 A;  4XFZ A;  1P7N A;  4LQW C;  1M9E C;  4U0E A;  4WYM A;  5HGK A;  1EIA A;  4U0F A;  4XRQ A;  2XGY A;  2PWO A;  3NTE A;  4NX4 C;  2PXR C;  2EIA A;  1U7K A;  3P05 A;  2GON A;  4U0A A;  4DGE C;  2M8P A;  1G03 A;  4HTW A;  5HGN A;  2GOL B;  4U0D A;  4XRO A;  2LF4 A;  2X2D D;  3H47 A;  2Y4Z A;  5HGM A;  4B4N A;  2X83 A;  4E91 A; 
#chains in the Genus database with same CATH topology
 2M8L A;  5HGO A;  2X82 A;  4DGA C;  3MGE A;  1EM9 A;  1AFV A;  1QRJ A;  1L6N A;  1E6J P;  2WLV A;  2V4X A;  1GWP A;  1M9X C;  1M9D C;  2WLV B;  4U0C A;  2XGU A;  4INB A;  1M9C C;  1M9F C;  4PH0 A;  5JPA A;  2M8N A;  2XDE A;  1AK4 C;  4XFX A;  4QNB A;  1M9Y C;  2PWM A;  2KGF A;  4J93 A;  4PH2 A;  3H4E A;  4PH3 A;  5HGL A;  2XGV A;  4U0B A;  4XFY A;  1D1D A;  2JPR A;  3BP9 A;  4E92 A;  4XFZ A;  1P7N A;  4LQW C;  1M9E C;  4U0E A;  4WYM A;  5HGK A;  1EIA A;  4U0F A;  4XRQ A;  2XGY A;  2PWO A;  3NTE A;  4NX4 C;  2PXR C;  2EIA A;  1U7K A;  3P05 A;  2GON A;  4U0A A;  4DGE C;  2M8P A;  1G03 A;  4HTW A;  5HGN A;  2GOL B;  4U0D A;  4XRO A;  2LF4 A;  2X2D D;  3H47 A;  2Y4Z A;  5HGM A;  4B4N A;  2X83 A;  4E91 A; 
#chains in the Genus database with same CATH homology
 2M8L A;  5HGO A;  2X82 A;  4DGA C;  3MGE A;  1EM9 A;  1AFV A;  1QRJ A;  1L6N A;  1E6J P;  2WLV A;  2V4X A;  1GWP A;  1M9X C;  1M9D C;  2WLV B;  4U0C A;  2XGU A;  4INB A;  1M9C C;  1M9F C;  4PH0 A;  5JPA A;  2M8N A;  2XDE A;  1AK4 C;  4XFX A;  4QNB A;  1M9Y C;  2PWM A;  2KGF A;  4J93 A;  4PH2 A;  3H4E A;  4PH3 A;  5HGL A;  2XGV A;  4U0B A;  4XFY A;  1D1D A;  2JPR A;  3BP9 A;  4E92 A;  4XFZ A;  1P7N A;  4LQW C;  1M9E C;  4U0E A;  4WYM A;  5HGK A;  1EIA A;  4U0F A;  4XRQ A;  2XGY A;  2PWO A;  3NTE A;  4NX4 C;  2PXR C;  2EIA A;  1U7K A;  3P05 A;  2GON A;  4U0A A;  4DGE C;  2M8P A;  1G03 A;  4HTW A;  5HGN A;  2GOL B;  4U0D A;  4XRO A;  2LF4 A;  2X2D D;  3H47 A;  2Y4Z A;  5HGM A;  4B4N A;  2X83 A;  4E91 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...