2X2D | Genus

Total Genus 50

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	50
sequence length	146
structure length	146
Chain Sequence	PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation pubmed doi rcsb
molecule keywords	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
molecule tags	Isomerase/viral protein
source organism	Homo sapiens
total genus	50
structure length	146
sequence length	146
chains with identical sequence	E
ec nomenclature	ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date	2010-01-12

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.375.10	Mainly Alpha	Orthogonal Bundle	Human Immunodeficiency Virus Type 1 Capsid Protein	Human Immunodeficiency Virus Type 1 Capsid Protein	2x2dD00

4PH0A 1E6JP 2XDEA 4U0CA 2M8LA 4QNBA 4XFZA 2WLVB 2LF4A 1QRJA 2M8NA 1M9YC 4LQWC 4WYMA 2Y4ZA 5HGKA 4XFYA 2KGFA 1GWPA 5HGNA 2WLVA 4U0BA 2XGUA 2XGYA 5JPAA 1U7KA 4HTWA 4E92A 1L6NA 1EM9A 4DGEC 4U0EA 3BP9A 2PWMA 4U0DA 2X2DD 1P7NA 4INBA 2V4XA 1AK4C 4E91A 2JPRA 4NX4C 4XRQA 4U0FA 3H47A 2X83A 2PXRC 4DGAC 4B4NA 1M9FC 1AFVA 3H4EA 3P05A 4U0AA 2XGVA 2GOLB 5HGLA 3NTEA 4PH2A 3MGEA 1G03A 4J93A 2M8PA 4PH3A 1M9CC 5HGOA 2X82A 4XROA 2GONA 1M9EC 4XFXA 1M9XC 5HGMA 2EIAA 2PWOA 1EIAA 1D1DA 1M9DC
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4PH0 A;  1E6J P;  2XDE A;  4U0C A;  2M8L A;  4QNB A;  4XFZ A;  2WLV B;  2LF4 A;  1QRJ A;  2M8N A;  1M9Y C;  4LQW C;  4WYM A;  2Y4Z A;  5HGK A;  4XFY A;  2KGF A;  1GWP A;  5HGN A;  2WLV A;  4U0B A;  2XGU A;  2XGY A;  5JPA A;  1U7K A;  4HTW A;  4E92 A;  1L6N A;  1EM9 A;  4DGE C;  4U0E A;  3BP9 A;  2PWM A;  4U0D A;  2X2D D;  1P7N A;  4INB A;  2V4X A;  1AK4 C;  4E91 A;  2JPR A;  4NX4 C;  4XRQ A;  4U0F A;  3H47 A;  2X83 A;  2PXR C;  4DGA C;  4B4N A;  1M9F C;  1AFV A;  3H4E A;  3P05 A;  4U0A A;  2XGV A;  2GOL B;  5HGL A;  3NTE A;  4PH2 A;  3MGE A;  1G03 A;  4J93 A;  2M8P A;  4PH3 A;  1M9C C;  5HGO A;  2X82 A;  4XRO A;  2GON A;  1M9E C;  4XFX A;  1M9X C;  5HGM A;  2EIA A;  2PWO A;  1EIA A;  1D1D A;  1M9D C; 
#chains in the Genus database with same CATH topology
 4PH0 A;  1E6J P;  2XDE A;  4U0C A;  2M8L A;  4QNB A;  4XFZ A;  2WLV B;  2LF4 A;  1QRJ A;  2M8N A;  1M9Y C;  4LQW C;  4WYM A;  2Y4Z A;  5HGK A;  4XFY A;  2KGF A;  1GWP A;  5HGN A;  2WLV A;  4U0B A;  2XGU A;  2XGY A;  5JPA A;  1U7K A;  4HTW A;  4E92 A;  1L6N A;  1EM9 A;  4DGE C;  4U0E A;  3BP9 A;  2PWM A;  4U0D A;  2X2D D;  1P7N A;  4INB A;  2V4X A;  1AK4 C;  4E91 A;  2JPR A;  4NX4 C;  4XRQ A;  4U0F A;  3H47 A;  2X83 A;  2PXR C;  4DGA C;  4B4N A;  1M9F C;  1AFV A;  3H4E A;  3P05 A;  4U0A A;  2XGV A;  2GOL B;  5HGL A;  3NTE A;  4PH2 A;  3MGE A;  1G03 A;  4J93 A;  2M8P A;  4PH3 A;  1M9C C;  5HGO A;  2X82 A;  4XRO A;  2GON A;  1M9E C;  4XFX A;  1M9X C;  5HGM A;  2EIA A;  2PWO A;  1EIA A;  1D1D A;  1M9D C; 
#chains in the Genus database with same CATH homology
 4PH0 A;  1E6J P;  2XDE A;  4U0C A;  2M8L A;  4QNB A;  4XFZ A;  2WLV B;  2LF4 A;  1QRJ A;  2M8N A;  1M9Y C;  4LQW C;  4WYM A;  2Y4Z A;  5HGK A;  4XFY A;  2KGF A;  1GWP A;  5HGN A;  2WLV A;  4U0B A;  2XGU A;  2XGY A;  5JPA A;  1U7K A;  4HTW A;  4E92 A;  1L6N A;  1EM9 A;  4DGE C;  4U0E A;  3BP9 A;  2PWM A;  4U0D A;  2X2D D;  1P7N A;  4INB A;  2V4X A;  1AK4 C;  4E91 A;  2JPR A;  4NX4 C;  4XRQ A;  4U0F A;  3H47 A;  2X83 A;  2PXR C;  4DGA C;  4B4N A;  1M9F C;  1AFV A;  3H4E A;  3P05 A;  4U0A A;  2XGV A;  2GOL B;  5HGL A;  3NTE A;  4PH2 A;  3MGE A;  1G03 A;  4J93 A;  2M8P A;  4PH3 A;  1M9C C;  5HGO A;  2X82 A;  4XRO A;  2GON A;  1M9E C;  4XFX A;  1M9X C;  5HGM A;  2EIA A;  2PWO A;  1EIA A;  1D1D A;  1M9D C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2X2DD

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN