2X83A

Evolutionary basis of hiv restriction by the antiretroviral trimcyp
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 CAPSID
total genus 49
structure length 146
sequence length 146
chains with identical sequence C
ec nomenclature
pdb deposition date 2010-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 2x83A00
4XFYA 2XGUA 2XGYA 4XFZA 1M9XC 5HGKA 4U0EA 2M8NA 2X82A 4XRQA 1P7NA 2X83A 4E91A 1M9FC 4U0FA 2PWOA 1QRJA 1GWPA 3P05A 3MGEA 4LQWC 3H4EA 1AFVA 3NTEA 4DGAC 5HGMA 1EIAA 2X2DD 2KGFA 4E92A 1AK4C 2JPRA 4U0DA 1EM9A 1U7KA 3BP9A 3H47A 2XGVA 4PH0A 4HTWA 2XDEA 1M9CC 4PH2A 1M9YC 4PH3A 4XROA 2PXRC 1D1DA 4B4NA 4INBA 1L6NA 2LF4A 2M8PA 1M9DC 4WYMA 5HGNA 1G03A 2M8LA 5HGLA 2WLVA 4U0BA 2EIAA 5HGOA 4NX4C 5JPAA 4XFXA 4QNBA 2Y4ZA 2V4XA 2GOLB 4DGEC 4J93A 2GONA 4U0AA 4U0CA 1M9EC 2WLVB 2PWMA 1E6JP
chains in the Genus database with same CATH superfamily
4XFYA 2XGUA 2XGYA 4XFZA 1M9XC 5HGKA 4U0EA 2M8NA 2X82A 4XRQA 1P7NA 2X83A 4E91A 1M9FC 4U0FA 2PWOA 1QRJA 1GWPA 3P05A 3MGEA 4LQWC 3H4EA 1AFVA 3NTEA 4DGAC 5HGMA 1EIAA 2X2DD 2KGFA 4E92A 1AK4C 2JPRA 4U0DA 1EM9A 1U7KA 3BP9A 3H47A 2XGVA 4PH0A 4HTWA 2XDEA 1M9CC 4PH2A 1M9YC 4PH3A 4XROA 2PXRC 1D1DA 4B4NA 4INBA 1L6NA 2LF4A 2M8PA 1M9DC 4WYMA 5HGNA 1G03A 2M8LA 5HGLA 2WLVA 4U0BA 2EIAA 5HGOA 4NX4C 5JPAA 4XFXA 4QNBA 2Y4ZA 2V4XA 2GOLB 4DGEC 4J93A 2GONA 4U0AA 4U0CA 1M9EC 2WLVB 2PWMA 1E6JP
chains in the Genus database with same CATH topology
4XFYA 2XGUA 2XGYA 4XFZA 1M9XC 5HGKA 4U0EA 2M8NA 2X82A 4XRQA 1P7NA 2X83A 4E91A 1M9FC 4U0FA 2PWOA 1QRJA 1GWPA 3P05A 3MGEA 4LQWC 3H4EA 1AFVA 3NTEA 4DGAC 5HGMA 1EIAA 2X2DD 2KGFA 4E92A 1AK4C 2JPRA 4U0DA 1EM9A 1U7KA 3BP9A 3H47A 2XGVA 4PH0A 4HTWA 2XDEA 1M9CC 4PH2A 1M9YC 4PH3A 4XROA 2PXRC 1D1DA 4B4NA 4INBA 1L6NA 2LF4A 2M8PA 1M9DC 4WYMA 5HGNA 1G03A 2M8LA 5HGLA 2WLVA 4U0BA 2EIAA 5HGOA 4NX4C 5JPAA 4XFXA 4QNBA 2Y4ZA 2V4XA 2GOLB 4DGEC 4J93A 2GONA 4U0AA 4U0CA 1M9EC 2WLVB 2PWMA 1E6JP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XFY A;  2XGU A;  2XGY A;  4XFZ A;  1M9X C;  5HGK A;  4U0E A;  2M8N A;  2X82 A;  4XRQ A;  1P7N A;  2X83 A;  4E91 A;  1M9F C;  4U0F A;  2PWO A;  1QRJ A;  1GWP A;  3P05 A;  3MGE A;  4LQW C;  3H4E A;  1AFV A;  3NTE A;  4DGA C;  5HGM A;  1EIA A;  2X2D D;  2KGF A;  4E92 A;  1AK4 C;  2JPR A;  4U0D A;  1EM9 A;  1U7K A;  3BP9 A;  3H47 A;  2XGV A;  4PH0 A;  4HTW A;  2XDE A;  1M9C C;  4PH2 A;  1M9Y C;  4PH3 A;  4XRO A;  2PXR C;  1D1D A;  4B4N A;  4INB A;  1L6N A;  2LF4 A;  2M8P A;  1M9D C;  4WYM A;  5HGN A;  1G03 A;  2M8L A;  5HGL A;  2WLV A;  4U0B A;  2EIA A;  5HGO A;  4NX4 C;  5JPA A;  4XFX A;  4QNB A;  2Y4Z A;  2V4X A;  2GOL B;  4DGE C;  4J93 A;  2GON A;  4U0A A;  4U0C A;  1M9E C;  2WLV B;  2PWM A;  1E6J P; 
#chains in the Genus database with same CATH topology
 4XFY A;  2XGU A;  2XGY A;  4XFZ A;  1M9X C;  5HGK A;  4U0E A;  2M8N A;  2X82 A;  4XRQ A;  1P7N A;  2X83 A;  4E91 A;  1M9F C;  4U0F A;  2PWO A;  1QRJ A;  1GWP A;  3P05 A;  3MGE A;  4LQW C;  3H4E A;  1AFV A;  3NTE A;  4DGA C;  5HGM A;  1EIA A;  2X2D D;  2KGF A;  4E92 A;  1AK4 C;  2JPR A;  4U0D A;  1EM9 A;  1U7K A;  3BP9 A;  3H47 A;  2XGV A;  4PH0 A;  4HTW A;  2XDE A;  1M9C C;  4PH2 A;  1M9Y C;  4PH3 A;  4XRO A;  2PXR C;  1D1D A;  4B4N A;  4INB A;  1L6N A;  2LF4 A;  2M8P A;  1M9D C;  4WYM A;  5HGN A;  1G03 A;  2M8L A;  5HGL A;  2WLV A;  4U0B A;  2EIA A;  5HGO A;  4NX4 C;  5JPA A;  4XFX A;  4QNB A;  2Y4Z A;  2V4X A;  2GOL B;  4DGE C;  4J93 A;  2GON A;  4U0A A;  4U0C A;  1M9E C;  2WLV B;  2PWM A;  1E6J P; 
#chains in the Genus database with same CATH homology
 4XFY A;  2XGU A;  2XGY A;  4XFZ A;  1M9X C;  5HGK A;  4U0E A;  2M8N A;  2X82 A;  4XRQ A;  1P7N A;  2X83 A;  4E91 A;  1M9F C;  4U0F A;  2PWO A;  1QRJ A;  1GWP A;  3P05 A;  3MGE A;  4LQW C;  3H4E A;  1AFV A;  3NTE A;  4DGA C;  5HGM A;  1EIA A;  2X2D D;  2KGF A;  4E92 A;  1AK4 C;  2JPR A;  4U0D A;  1EM9 A;  1U7K A;  3BP9 A;  3H47 A;  2XGV A;  4PH0 A;  4HTW A;  2XDE A;  1M9C C;  4PH2 A;  1M9Y C;  4PH3 A;  4XRO A;  2PXR C;  1D1D A;  4B4N A;  4INB A;  1L6N A;  2LF4 A;  2M8P A;  1M9D C;  4WYM A;  5HGN A;  1G03 A;  2M8L A;  5HGL A;  2WLV A;  4U0B A;  2EIA A;  5HGO A;  4NX4 C;  5JPA A;  4XFX A;  4QNB A;  2Y4Z A;  2V4X A;  2GOL B;  4DGE C;  4J93 A;  2GON A;  4U0A A;  4U0C A;  1M9E C;  2WLV B;  2PWM A;  1E6J P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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