2X83A

Evolutionary basis of hiv restriction by the antiretroviral trimcyp
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 CAPSID
total genus 49
structure length 146
sequence length 146
chains with identical sequence C
ec nomenclature
pdb deposition date 2010-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 2x83A00
4U0EA 5HGMA 5HGOA 1U7KA 4B4NA 4HTWA 1EIAA 2XGVA 4XFYA 1AFVA 2XGUA 4PH0A 4QNBA 4XROA 2X83A 4U0FA 1E6JP 4U0DA 4U0AA 2X2DD 3NTEA 4INBA 1M9CC 1M9FC 1L6NA 2PWMA 1M9DC 2XDEA 3H4EA 1EM9A 2XGYA 3MGEA 1AK4C 3H47A 1D1DA 4U0BA 2M8NA 4PH3A 2WLVA 1M9YC 2KGFA 4U0CA 2WLVB 5JPAA 1GWPA 2GOLB 4E91A 2M8LA 4DGAC 4WYMA 4NX4C 2GONA 4XFZA 3P05A 2V4XA 3BP9A 1M9EC 5HGKA 4DGEC 4PH2A 4XFXA 2LF4A 2EIAA 2PWOA 1G03A 2JPRA 4E92A 4LQWC 2PXRC 5HGNA 1QRJA 4J93A 4XRQA 2M8PA 1P7NA 1M9XC 2X82A 5HGLA 2Y4ZA
chains in the Genus database with same CATH superfamily
4U0EA 5HGMA 5HGOA 1U7KA 4B4NA 4HTWA 1EIAA 2XGVA 4XFYA 1AFVA 2XGUA 4PH0A 4QNBA 4XROA 2X83A 4U0FA 1E6JP 4U0DA 4U0AA 2X2DD 3NTEA 4INBA 1M9CC 1M9FC 1L6NA 2PWMA 1M9DC 2XDEA 3H4EA 1EM9A 2XGYA 3MGEA 1AK4C 3H47A 1D1DA 4U0BA 2M8NA 4PH3A 2WLVA 1M9YC 2KGFA 4U0CA 2WLVB 5JPAA 1GWPA 2GOLB 4E91A 2M8LA 4DGAC 4WYMA 4NX4C 2GONA 4XFZA 3P05A 2V4XA 3BP9A 1M9EC 5HGKA 4DGEC 4PH2A 4XFXA 2LF4A 2EIAA 2PWOA 1G03A 2JPRA 4E92A 4LQWC 2PXRC 5HGNA 1QRJA 4J93A 4XRQA 2M8PA 1P7NA 1M9XC 2X82A 5HGLA 2Y4ZA
chains in the Genus database with same CATH topology
4U0EA 5HGMA 5HGOA 1U7KA 4B4NA 4HTWA 1EIAA 2XGVA 4XFYA 1AFVA 2XGUA 4PH0A 4QNBA 4XROA 2X83A 4U0FA 1E6JP 4U0DA 4U0AA 2X2DD 3NTEA 4INBA 1M9CC 1M9FC 1L6NA 2PWMA 1M9DC 2XDEA 3H4EA 1EM9A 2XGYA 3MGEA 1AK4C 3H47A 1D1DA 4U0BA 2M8NA 4PH3A 2WLVA 1M9YC 2KGFA 4U0CA 2WLVB 5JPAA 1GWPA 2GOLB 4E91A 2M8LA 4DGAC 4WYMA 4NX4C 2GONA 4XFZA 3P05A 2V4XA 3BP9A 1M9EC 5HGKA 4DGEC 4PH2A 4XFXA 2LF4A 2EIAA 2PWOA 1G03A 2JPRA 4E92A 4LQWC 2PXRC 5HGNA 1QRJA 4J93A 4XRQA 2M8PA 1P7NA 1M9XC 2X82A 5HGLA 2Y4ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U0E A;  5HGM A;  5HGO A;  1U7K A;  4B4N A;  4HTW A;  1EIA A;  2XGV A;  4XFY A;  1AFV A;  2XGU A;  4PH0 A;  4QNB A;  4XRO A;  2X83 A;  4U0F A;  1E6J P;  4U0D A;  4U0A A;  2X2D D;  3NTE A;  4INB A;  1M9C C;  1M9F C;  1L6N A;  2PWM A;  1M9D C;  2XDE A;  3H4E A;  1EM9 A;  2XGY A;  3MGE A;  1AK4 C;  3H47 A;  1D1D A;  4U0B A;  2M8N A;  4PH3 A;  2WLV A;  1M9Y C;  2KGF A;  4U0C A;  2WLV B;  5JPA A;  1GWP A;  2GOL B;  4E91 A;  2M8L A;  4DGA C;  4WYM A;  4NX4 C;  2GON A;  4XFZ A;  3P05 A;  2V4X A;  3BP9 A;  1M9E C;  5HGK A;  4DGE C;  4PH2 A;  4XFX A;  2LF4 A;  2EIA A;  2PWO A;  1G03 A;  2JPR A;  4E92 A;  4LQW C;  2PXR C;  5HGN A;  1QRJ A;  4J93 A;  4XRQ A;  2M8P A;  1P7N A;  1M9X C;  2X82 A;  5HGL A;  2Y4Z A; 
#chains in the Genus database with same CATH topology
 4U0E A;  5HGM A;  5HGO A;  1U7K A;  4B4N A;  4HTW A;  1EIA A;  2XGV A;  4XFY A;  1AFV A;  2XGU A;  4PH0 A;  4QNB A;  4XRO A;  2X83 A;  4U0F A;  1E6J P;  4U0D A;  4U0A A;  2X2D D;  3NTE A;  4INB A;  1M9C C;  1M9F C;  1L6N A;  2PWM A;  1M9D C;  2XDE A;  3H4E A;  1EM9 A;  2XGY A;  3MGE A;  1AK4 C;  3H47 A;  1D1D A;  4U0B A;  2M8N A;  4PH3 A;  2WLV A;  1M9Y C;  2KGF A;  4U0C A;  2WLV B;  5JPA A;  1GWP A;  2GOL B;  4E91 A;  2M8L A;  4DGA C;  4WYM A;  4NX4 C;  2GON A;  4XFZ A;  3P05 A;  2V4X A;  3BP9 A;  1M9E C;  5HGK A;  4DGE C;  4PH2 A;  4XFX A;  2LF4 A;  2EIA A;  2PWO A;  1G03 A;  2JPR A;  4E92 A;  4LQW C;  2PXR C;  5HGN A;  1QRJ A;  4J93 A;  4XRQ A;  2M8P A;  1P7N A;  1M9X C;  2X82 A;  5HGL A;  2Y4Z A; 
#chains in the Genus database with same CATH homology
 4U0E A;  5HGM A;  5HGO A;  1U7K A;  4B4N A;  4HTW A;  1EIA A;  2XGV A;  4XFY A;  1AFV A;  2XGU A;  4PH0 A;  4QNB A;  4XRO A;  2X83 A;  4U0F A;  1E6J P;  4U0D A;  4U0A A;  2X2D D;  3NTE A;  4INB A;  1M9C C;  1M9F C;  1L6N A;  2PWM A;  1M9D C;  2XDE A;  3H4E A;  1EM9 A;  2XGY A;  3MGE A;  1AK4 C;  3H47 A;  1D1D A;  4U0B A;  2M8N A;  4PH3 A;  2WLV A;  1M9Y C;  2KGF A;  4U0C A;  2WLV B;  5JPA A;  1GWP A;  2GOL B;  4E91 A;  2M8L A;  4DGA C;  4WYM A;  4NX4 C;  2GON A;  4XFZ A;  3P05 A;  2V4X A;  3BP9 A;  1M9E C;  5HGK A;  4DGE C;  4PH2 A;  4XFX A;  2LF4 A;  2EIA A;  2PWO A;  1G03 A;  2JPR A;  4E92 A;  4LQW C;  2PXR C;  5HGN A;  1QRJ A;  4J93 A;  4XRQ A;  2M8P A;  1P7N A;  1M9X C;  2X82 A;  5HGL A;  2Y4Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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