2X2DD

Acetyl-cypa:hiv-1 n-term capsid domain complex
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
total genus 50
structure length 146
sequence length 146
chains with identical sequence E
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2010-01-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 2x2dD00
1AFVA 2X2DD 2LF4A 2XGYA 3H47A 4B4NA 4PH3A 4J93A 5HGOA 2XGUA 2EIAA 2XGVA 2X82A 4U0CA 4HTWA 1D1DA 2PWOA 2M8LA 3NTEA 4E91A 3P05A 5HGKA 5HGMA 2JPRA 4PH2A 2PWMA 4LQWC 1E6JP 5HGLA 1M9DC 1M9FC 4INBA 4U0FA 1EM9A 2PXRC 4XRQA 1M9EC 1GWPA 1AK4C 2XDEA 2V4XA 5HGNA 4XFZA 4QNBA 2M8NA 1EIAA 3BP9A 2GOLB 3MGEA 1U7KA 1M9YC 1L6NA 5JPAA 1M9CC 4U0DA 4U0BA 2WLVA 2Y4ZA 2M8PA 2GONA 4XFXA 4PH0A 2WLVB 4XFYA 4U0AA 2X83A 4E92A 2KGFA 1P7NA 1QRJA 4NX4C 4WYMA 4XROA 4U0EA 4DGEC 1M9XC 3H4EA 1G03A 4DGAC
chains in the Genus database with same CATH superfamily
1AFVA 2X2DD 2LF4A 2XGYA 3H47A 4B4NA 4PH3A 4J93A 5HGOA 2XGUA 2EIAA 2XGVA 2X82A 4U0CA 4HTWA 1D1DA 2PWOA 2M8LA 3NTEA 4E91A 3P05A 5HGKA 5HGMA 2JPRA 4PH2A 2PWMA 4LQWC 1E6JP 5HGLA 1M9DC 1M9FC 4INBA 4U0FA 1EM9A 2PXRC 4XRQA 1M9EC 1GWPA 1AK4C 2XDEA 2V4XA 5HGNA 4XFZA 4QNBA 2M8NA 1EIAA 3BP9A 2GOLB 3MGEA 1U7KA 1M9YC 1L6NA 5JPAA 1M9CC 4U0DA 4U0BA 2WLVA 2Y4ZA 2M8PA 2GONA 4XFXA 4PH0A 2WLVB 4XFYA 4U0AA 2X83A 4E92A 2KGFA 1P7NA 1QRJA 4NX4C 4WYMA 4XROA 4U0EA 4DGEC 1M9XC 3H4EA 1G03A 4DGAC
chains in the Genus database with same CATH topology
1AFVA 2X2DD 2LF4A 2XGYA 3H47A 4B4NA 4PH3A 4J93A 5HGOA 2XGUA 2EIAA 2XGVA 2X82A 4U0CA 4HTWA 1D1DA 2PWOA 2M8LA 3NTEA 4E91A 3P05A 5HGKA 5HGMA 2JPRA 4PH2A 2PWMA 4LQWC 1E6JP 5HGLA 1M9DC 1M9FC 4INBA 4U0FA 1EM9A 2PXRC 4XRQA 1M9EC 1GWPA 1AK4C 2XDEA 2V4XA 5HGNA 4XFZA 4QNBA 2M8NA 1EIAA 3BP9A 2GOLB 3MGEA 1U7KA 1M9YC 1L6NA 5JPAA 1M9CC 4U0DA 4U0BA 2WLVA 2Y4ZA 2M8PA 2GONA 4XFXA 4PH0A 2WLVB 4XFYA 4U0AA 2X83A 4E92A 2KGFA 1P7NA 1QRJA 4NX4C 4WYMA 4XROA 4U0EA 4DGEC 1M9XC 3H4EA 1G03A 4DGAC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AFV A;  2X2D D;  2LF4 A;  2XGY A;  3H47 A;  4B4N A;  4PH3 A;  4J93 A;  5HGO A;  2XGU A;  2EIA A;  2XGV A;  2X82 A;  4U0C A;  4HTW A;  1D1D A;  2PWO A;  2M8L A;  3NTE A;  4E91 A;  3P05 A;  5HGK A;  5HGM A;  2JPR A;  4PH2 A;  2PWM A;  4LQW C;  1E6J P;  5HGL A;  1M9D C;  1M9F C;  4INB A;  4U0F A;  1EM9 A;  2PXR C;  4XRQ A;  1M9E C;  1GWP A;  1AK4 C;  2XDE A;  2V4X A;  5HGN A;  4XFZ A;  4QNB A;  2M8N A;  1EIA A;  3BP9 A;  2GOL B;  3MGE A;  1U7K A;  1M9Y C;  1L6N A;  5JPA A;  1M9C C;  4U0D A;  4U0B A;  2WLV A;  2Y4Z A;  2M8P A;  2GON A;  4XFX A;  4PH0 A;  2WLV B;  4XFY A;  4U0A A;  2X83 A;  4E92 A;  2KGF A;  1P7N A;  1QRJ A;  4NX4 C;  4WYM A;  4XRO A;  4U0E A;  4DGE C;  1M9X C;  3H4E A;  1G03 A;  4DGA C; 
#chains in the Genus database with same CATH topology
 1AFV A;  2X2D D;  2LF4 A;  2XGY A;  3H47 A;  4B4N A;  4PH3 A;  4J93 A;  5HGO A;  2XGU A;  2EIA A;  2XGV A;  2X82 A;  4U0C A;  4HTW A;  1D1D A;  2PWO A;  2M8L A;  3NTE A;  4E91 A;  3P05 A;  5HGK A;  5HGM A;  2JPR A;  4PH2 A;  2PWM A;  4LQW C;  1E6J P;  5HGL A;  1M9D C;  1M9F C;  4INB A;  4U0F A;  1EM9 A;  2PXR C;  4XRQ A;  1M9E C;  1GWP A;  1AK4 C;  2XDE A;  2V4X A;  5HGN A;  4XFZ A;  4QNB A;  2M8N A;  1EIA A;  3BP9 A;  2GOL B;  3MGE A;  1U7K A;  1M9Y C;  1L6N A;  5JPA A;  1M9C C;  4U0D A;  4U0B A;  2WLV A;  2Y4Z A;  2M8P A;  2GON A;  4XFX A;  4PH0 A;  2WLV B;  4XFY A;  4U0A A;  2X83 A;  4E92 A;  2KGF A;  1P7N A;  1QRJ A;  4NX4 C;  4WYM A;  4XRO A;  4U0E A;  4DGE C;  1M9X C;  3H4E A;  1G03 A;  4DGA C; 
#chains in the Genus database with same CATH homology
 1AFV A;  2X2D D;  2LF4 A;  2XGY A;  3H47 A;  4B4N A;  4PH3 A;  4J93 A;  5HGO A;  2XGU A;  2EIA A;  2XGV A;  2X82 A;  4U0C A;  4HTW A;  1D1D A;  2PWO A;  2M8L A;  3NTE A;  4E91 A;  3P05 A;  5HGK A;  5HGM A;  2JPR A;  4PH2 A;  2PWM A;  4LQW C;  1E6J P;  5HGL A;  1M9D C;  1M9F C;  4INB A;  4U0F A;  1EM9 A;  2PXR C;  4XRQ A;  1M9E C;  1GWP A;  1AK4 C;  2XDE A;  2V4X A;  5HGN A;  4XFZ A;  4QNB A;  2M8N A;  1EIA A;  3BP9 A;  2GOL B;  3MGE A;  1U7K A;  1M9Y C;  1L6N A;  5JPA A;  1M9C C;  4U0D A;  4U0B A;  2WLV A;  2Y4Z A;  2M8P A;  2GON A;  4XFX A;  4PH0 A;  2WLV B;  4XFY A;  4U0A A;  2X83 A;  4E92 A;  2KGF A;  1P7N A;  1QRJ A;  4NX4 C;  4WYM A;  4XRO A;  4U0E A;  4DGE C;  1M9X C;  3H4E A;  1G03 A;  4DGA C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...