3SP8A

Crystal structure of nk2 in complex with fractionated heparin dp10
Total Genus 77
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
255
structure length
255
Chain Sequence
RRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSDIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTSNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCKIKTCK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hormone
source organism Homo sapiens
publication title Crystal structure of NK2 in complex with fractionated Heparin DP10
rcsb
molecule keywords Hepatocyte growth factor alpha chain
total genus 77
structure length 255
sequence length 255
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 3sp8A02
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 3sp8A03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 3sp8A01
1CEBA 4Z0EA 1PMKA 2K4RA 5CT2A 4BVWA 2J8JA 1I5KA 2YIPA 1BHTA 1Z40A 1KDUA 2YILA 4HZHA 1NL1A 1NL2A 1NK1A 5CS1A 2Q8BA 1PK4A 1GP9A 1I8NA 5EOKA 4R1CA 5CS9A 4R1BA 4APLA 3BT2A 5CS3A 2FEBA 2PK4A 4UAOA 4R1AA 2I9AA 1KIVA 4Z0FA 4Z0DA 5EODA 2Z8VA 5CT1A 1KI0A 2Q8AA 1JFNA 4A5TS 2PF1A 2PF2A 3BT1A 1YXEA 3HMSA 4DURA 2YIOA 2Y8RA 2DOIA 3SP8A 4O03A 2J8LA 4R19A 1HKYA 3HMRA 1HPKA 1TPKA 4IUAA 1CEAA 4KIVA 4UV6A 2Z8WA 3K65A 2LL3A 5CSQA 1KRNA 4D3CA 4APMA 2HPPP 1W8KA 5CP9A 5CS5A 1A0HA 3LAQA 4Z09A 2QJ4A 5CT3A 4BVVA 2LL4M 3U73A 2X2ZA 4CIKA 1W81A 4BV7A 3SRIA 4BVCA 5COEA 1I71A 1PKRA 2K13X 3E6PL 5I25A 3NXPA 2HPQP 3ZWZA 1GMOA 4BV5A 4BVDA 3HMTA 2DOHX 2FD6A 1B2IA 4NZQA 1HPJA 2F83A 1PK2A 2I9BA 3SRJA 3HN4A 3MKPA 2K51A 2QJ2A 2HGFA 2KNFA 5HPGA 1URKA 1PMLA 2L0SA 3ZLEA 1GMNA 2KJ4A 3KIVA 2SPTA
chains in the Genus database with same CATH superfamily
1CEBA 4YIZA 4Z0EA 1PMKA 2K4RA 5CT2A 4BVWA 2J8JA 1I5KA 2YIPA 1BHTA 1Z40A 1KDUA 2YILA 4HZHA 1NL1A 1NL2A 1NK1A 5CS1A 2Q8BA 1PK4A 1GP9A 1I8NA 5EOKA 4R1CA 5CS9A 4R1BA 4APLA 3BT2A 5CS3A 2FEBA 2PK4A 4UAOA 4R1AA 2I9AA 1KIVA 4Z0FA 4Z0DA 5EODA 2Z8VA 5CT1A 1KI0A 2Q8AA 1JFNA 4A5TS 2PF1A 2PF2A 3BT1A 1YXEA 3HMSA 4DURA 2YIOA 2Y8RA 2DOIA 3SP8A 4O03A 2J8LA 4R19A 1HKYA 3HMRA 1HPKA 1TPKA 4IUAA 1CEAA 4KIVA 4UV6A 2Z8WA 3K65A 2LL3A 5CSQA 1KRNA 4D3CA 4APMA 2HPPP 1W8KA 5CP9A 5CS5A 1A0HA 3LAQA 4Z09A 2QJ4A 2KL5A 5CT3A 4BVVA 2LL4M 3U73A 2X2ZA 4CIKA 1W81A 4BV7A 3SRIA 4BVCA 5COEA 1I71A 1PKRA 2K13X 3E6PL 5I25A 3NXPA 2HPQP 3ZWZA 1GMOA 4BV5A 4BVDA 3HMTA 2DOHX 2FD6A 1B2IA 4NZQA 1HPJA 2F83A 1PK2A 2I9BA 3SRJA 3HN4A 3MKPA 2K51A 2QJ2A 2HGFA 2KNFA 5HPGA 1URKA 1PMLA 2L0SA 3ZLEA 1GMNA 2KJ4A 3KIVA 4YIVA 2SPTA
chains in the Genus database with same CATH topology
1CEBA 4YIZA 4Z0EA 1PMKA 2K4RA 5CT2A 4BVWA 2J8JA 1I5KA 2YIPA 1BHTA 1Z40A 1KDUA 2YILA 4HZHA 1NL1A 1NL2A 1NK1A 5CS1A 2Q8BA 1PK4A 1GP9A 1I8NA 5EOKA 4R1CA 5CS9A 4R1BA 4APLA 3BT2A 5CS3A 2FEBA 2PK4A 4UAOA 4R1AA 2I9AA 1KIVA 4Z0FA 4Z0DA 5EODA 2Z8VA 5CT1A 1KI0A 2Q8AA 1JFNA 4A5TS 2PF1A 2PF2A 3BT1A 1YXEA 3HMSA 4DURA 2YIOA 2Y8RA 2DOIA 3SP8A 4O03A 2J8LA 4R19A 1HKYA 3HMRA 1HPKA 1TPKA 4IUAA 1CEAA 4KIVA 4UV6A 2Z8WA 3K65A 2LL3A 5CSQA 1KRNA 4D3CA 4APMA 2HPPP 1W8KA 5CP9A 5CS5A 1A0HA 3LAQA 4Z09A 2QJ4A 2KL5A 5CT3A 4BVVA 2LL4M 3U73A 2X2ZA 4CIKA 1W81A 4BV7A 3SRIA 4BVCA 5COEA 1I71A 1PKRA 2K13X 3E6PL 5I25A 3NXPA 2HPQP 3ZWZA 1GMOA 4BV5A 4BVDA 3HMTA 2DOHX 2FD6A 1B2IA 4NZQA 1HPJA 2F83A 1PK2A 2I9BA 3SRJA 3HN4A 3MKPA 2K51A 2QJ2A 2HGFA 2KNFA 5HPGA 1URKA 1PMLA 2L0SA 3ZLEA 1GMNA 2KJ4A 3KIVA 4YIVA 2SPTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CEB A;  4Z0E A;  1PMK A;  2K4R A;  5CT2 A;  4BVW A;  2J8J A;  1I5K A;  2YIP A;  1BHT A;  1Z40 A;  1KDU A;  2YIL A;  4HZH A;  1NL1 A;  1NL2 A;  1NK1 A;  5CS1 A;  2Q8B A;  1PK4 A;  1GP9 A;  1I8N A;  5EOK A;  4R1C A;  5CS9 A;  4R1B A;  4APL A;  3BT2 A;  5CS3 A;  2FEB A;  2PK4 A;  4UAO A;  4R1A A;  2I9A A;  1KIV A;  4Z0F A;  4Z0D A;  5EOD A;  2Z8V A;  5CT1 A;  1KI0 A;  2Q8A A;  1JFN A;  4A5T S;  2PF1 A;  2PF2 A;  3BT1 A;  1YXE A;  3HMS A;  4DUR A;  2YIO A;  2Y8R A;  2DOI A;  3SP8 A;  4O03 A;  2J8L A;  4R19 A;  1HKY A;  3HMR A;  1HPK A;  1TPK A;  4IUA A;  1CEA A;  4KIV A;  4UV6 A;  2Z8W A;  3K65 A;  2LL3 A;  5CSQ A;  1KRN A;  4D3C A;  4APM A;  2HPP P;  1W8K A;  5CP9 A;  5CS5 A;  1A0H A;  3LAQ A;  4Z09 A;  2QJ4 A;  5CT3 A;  4BVV A;  2LL4 M;  3U73 A;  2X2Z A;  4CIK A;  1W81 A;  4BV7 A;  3SRI A;  4BVC A;  5COE A;  1I71 A;  1PKR A;  2K13 X;  3E6P L;  5I25 A;  3NXP A;  2HPQ P;  3ZWZ A;  1GMO A;  4BV5 A;  4BVD A;  3HMT A;  2DOH X;  2FD6 A;  1B2I A;  4NZQ A;  1HPJ A;  2F83 A;  1PK2 A;  2I9B A;  3SRJ A;  3HN4 A;  3MKP A;  2K51 A;  2QJ2 A;  2HGF A;  2KNF A;  5HPG A;  1URK A;  1PML A;  2L0S A;  3ZLE A;  1GMN A;  2KJ4 A;  3KIV A;  2SPT A; 
#chains in the Genus database with same CATH topology
 1CEB A;  4YIZ A;  4Z0E A;  1PMK A;  2K4R A;  5CT2 A;  4BVW A;  2J8J A;  1I5K A;  2YIP A;  1BHT A;  1Z40 A;  1KDU A;  2YIL A;  4HZH A;  1NL1 A;  1NL2 A;  1NK1 A;  5CS1 A;  2Q8B A;  1PK4 A;  1GP9 A;  1I8N A;  5EOK A;  4R1C A;  5CS9 A;  4R1B A;  4APL A;  3BT2 A;  5CS3 A;  2FEB A;  2PK4 A;  4UAO A;  4R1A A;  2I9A A;  1KIV A;  4Z0F A;  4Z0D A;  5EOD A;  2Z8V A;  5CT1 A;  1KI0 A;  2Q8A A;  1JFN A;  4A5T S;  2PF1 A;  2PF2 A;  3BT1 A;  1YXE A;  3HMS A;  4DUR A;  2YIO A;  2Y8R A;  2DOI A;  3SP8 A;  4O03 A;  2J8L A;  4R19 A;  1HKY A;  3HMR A;  1HPK A;  1TPK A;  4IUA A;  1CEA A;  4KIV A;  4UV6 A;  2Z8W A;  3K65 A;  2LL3 A;  5CSQ A;  1KRN A;  4D3C A;  4APM A;  2HPP P;  1W8K A;  5CP9 A;  5CS5 A;  1A0H A;  3LAQ A;  4Z09 A;  2QJ4 A;  2KL5 A;  5CT3 A;  4BVV A;  2LL4 M;  3U73 A;  2X2Z A;  4CIK A;  1W81 A;  4BV7 A;  3SRI A;  4BVC A;  5COE A;  1I71 A;  1PKR A;  2K13 X;  3E6P L;  5I25 A;  3NXP A;  2HPQ P;  3ZWZ A;  1GMO A;  4BV5 A;  4BVD A;  3HMT A;  2DOH X;  2FD6 A;  1B2I A;  4NZQ A;  1HPJ A;  2F83 A;  1PK2 A;  2I9B A;  3SRJ A;  3HN4 A;  3MKP A;  2K51 A;  2QJ2 A;  2HGF A;  2KNF A;  5HPG A;  1URK A;  1PML A;  2L0S A;  3ZLE A;  1GMN A;  2KJ4 A;  3KIV A;  4YIV A;  2SPT A; 
#chains in the Genus database with same CATH homology
 1CEB A;  4YIZ A;  4Z0E A;  1PMK A;  2K4R A;  5CT2 A;  4BVW A;  2J8J A;  1I5K A;  2YIP A;  1BHT A;  1Z40 A;  1KDU A;  2YIL A;  4HZH A;  1NL1 A;  1NL2 A;  1NK1 A;  5CS1 A;  2Q8B A;  1PK4 A;  1GP9 A;  1I8N A;  5EOK A;  4R1C A;  5CS9 A;  4R1B A;  4APL A;  3BT2 A;  5CS3 A;  2FEB A;  2PK4 A;  4UAO A;  4R1A A;  2I9A A;  1KIV A;  4Z0F A;  4Z0D A;  5EOD A;  2Z8V A;  5CT1 A;  1KI0 A;  2Q8A A;  1JFN A;  4A5T S;  2PF1 A;  2PF2 A;  3BT1 A;  1YXE A;  3HMS A;  4DUR A;  2YIO A;  2Y8R A;  2DOI A;  3SP8 A;  4O03 A;  2J8L A;  4R19 A;  1HKY A;  3HMR A;  1HPK A;  1TPK A;  4IUA A;  1CEA A;  4KIV A;  4UV6 A;  2Z8W A;  3K65 A;  2LL3 A;  5CSQ A;  1KRN A;  4D3C A;  4APM A;  2HPP P;  1W8K A;  5CP9 A;  5CS5 A;  1A0H A;  3LAQ A;  4Z09 A;  2QJ4 A;  2KL5 A;  5CT3 A;  4BVV A;  2LL4 M;  3U73 A;  2X2Z A;  4CIK A;  1W81 A;  4BV7 A;  3SRI A;  4BVC A;  5COE A;  1I71 A;  1PKR A;  2K13 X;  3E6P L;  5I25 A;  3NXP A;  2HPQ P;  3ZWZ A;  1GMO A;  4BV5 A;  4BVD A;  3HMT A;  2DOH X;  2FD6 A;  1B2I A;  4NZQ A;  1HPJ A;  2F83 A;  1PK2 A;  2I9B A;  3SRJ A;  3HN4 A;  3MKP A;  2K51 A;  2QJ2 A;  2HGF A;  2KNF A;  5HPG A;  1URK A;  1PML A;  2L0S A;  3ZLE A;  1GMN A;  2KJ4 A;  3KIV A;  4YIV A;  2SPT A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...