3NC2A

X-ray structure of ketohexokinase with a quinazoline
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
296
structure length
296
Chain Sequence
GSQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Electron density guided fragment-based lead discovery of ketohexokinase inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Ketohexokinase
total genus 104
structure length 296
sequence length 296
chains with identical sequence B
ec nomenclature ec 2.7.1.3: Ketohexokinase.
pdb deposition date 2010-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.20 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase 3nc2A00
4N09A 2JGVA 3DZVA 3KEUA 5BYDA 1V1SA 4E84A 3B1OA 3KD6A 1GC5A 3N1CA 2YXTA 2AJPA 2DCNA 1ESQA 3B1RA 4C5JA 2AFBA 3HYOA 1RKSA 2A9ZA 1U2XA 3RPHA 1RK2A 1KYHA 4JJPA 1RKDA 2A9YA 1LIKA 3RQHA 3FHXA 2I6AA 4LBXA 3NCAA 4LBGA 1LHPA 2YXUA 2PKMA 5EYNA 3VASA 3UBOA 3RQ5A 3NL2A 3VAQA 1EKKA 3RSFA 4S1IB 3HPDA 2DDMA 3RTBA 1L2LA 1LIOA 3DRWA 4B8SA 3KTNA 3RSGA 3GBUA 5EY7A 4KANA 2I6BA 2QCVA 2XTBA 4K8KA 1V1BA 2F7KA 2HW1A 1VI9A 1YGKA 4EBUA 1V19A 3RSSA 1UA4A 2AJRA 3K9EA 3I3YA 5CM5A 4E69A 3NBWA 5COJA 2AA0A 3RQ8A 2HLZA 3IQ0A 3K5WA 1TZ6A 5BYFA 5BYEA 2C4EA 3H74A 1TD2A 3JULA 3NM3A 3RRFA 3RT9A 5C3ZA 3IKHA 3IN1A 5TRWA 3ZS7A 2R3BA 3RSQA 1EKQA 3OTXA 2NWHA 1VM7A 3RTCA 4XCKA 2JG5A 1JXIA 4B8RA 2VARA 4U7XA 2Q5RA 4GM6A 5B6AA 3EWMA 1JXHA 1UB0A 4E3AA 3RS8A 5C41A 2ABSA 2AX3A 3PZSA 4EN4A 5F0ZA 3RREA 4JKSA 3RTEA 3CQDA 3IH0A 3W4SA 3UMPA 3FHYA 3H49A 3RTDA 5CGEA 3QAIA 4C5MA 3KZHA 2PKKA 4K8CA 4S1HA 3RT7A 3Q92A 3NBVA 4DU5A 1YHJA 4E8YA 1RFTA 1WYEA 2DDWA 3RRBA 4LC4A 4EUMA 2QHPA 4O1GA 1LIJA 2JG1A 1LHRA 2PKFA 4JKUA 2V78A 4S1MA 3RO4A 3NL5A 3RRJA 4E8WA 3UQ6A 1YGJA 4S1IA 4KALA 1RFVA 3UQDA 2AB8A 1LIIA 3PL2A 4EOHA 3IBQA 1TYYA 3LKIA 2PKNA 2RBCA 4K9IA 3RS9A 1V1AA 4X8FA 3RU3A 4C5LA 5BYCA 3GO6A 4KAHA 4DC3A 3B1NA 3BF5A 3Q1YA 3RQ6A 3MBJA 4KADA 1C3QA 3RU2A 2AWDA 1VK4A 3NC9A 2C49A 1BX4A 3NL6A 4C5KA 4E8ZA 5F11A 2DDOA 4K8TA 4O1LA 3RTAA 3UQEA 4PVVA 2FV7A 4K93A 2R3EA 5CGAA 3RPZA 4WJMA 1ESJA 4K8PA 3LHXA 4K9CA 5C40A 3LJSA 5TQIA 3RTGA 1TZ3A 4C5NA 3MBHA 3NL3A 3GO7A 3RQ2A 4UBEA 1RFUA 3BGKA 3UQ9A 3UMOA 4YWRA 5C3YA 2ABQA 3B3LA 4KBEA 3B1PA 4XF6A 3RQXA 3HICA 2F02A 4YL5A 4XF7A 1RKAA 3QA2A 3RY7A 4XDAA 3IE7A 3RM5A 1GQTA 2I5BA 3LOOA 2HQQA 3B1QA 3NM1A 4N08A 4LCAA 3NC2A 1DGMA 3RQQA
chains in the Genus database with same CATH superfamily
2JGVA 3DZVA 2JFHA 5BYDA 2VOSA 3KD6A 2YXTA 2DCNA 4C5JA 2AFBA 3RPHA 2A9YA 4HV4A 2I6AA 4LBGA 3UBOA 2DDMA 3KTNA 2QCVA 1EEHA 3I3YA 5COJA 3IQ0A 5BYFA 3RT9A 3IN1A 2JG5A 5B6AA 1UB0A 2GC5A 5C41A 3ZL8A 4EN4A 3RTEA 3IH0A 3FHYA 4C5MA 2PKKA 4S1HA 4CVMA 3RRBA 1UAGA 4S1MA 2V78A 2XJAA 4S1IA 3PL2A 3RU3A 2RBCA 4X8FA 3BF5A 4QF5A 3ZM6A 4K8TA 4C12A 3UQEA 2R3EA 5CGAA 4WJMA 1ESJA 4K8PA 3LHXA 4K9CA 2GC6A 3NL3A 1RFUA 5C3YA 4KBEA 3RQXA 2F02A 1RKAA 2AM1A 2I5BA 3KEUA 3N1CA 1GC5A 1RK2A 1RKDA 1LIKA 3FHXA 3RQ5A 4ZIYA 3RSFA 4S1IB 1L2LA 3RSGA 3GBUA 1W78A 5EY7A 2XTBA 4K8KA 5A5EA 4EBUA 3RSSA 3RQ8A 2AA0A 2HLZA 5BYEA 3JULA 3IKHA 1FGSA 5TRWA 1EKQA 3OTXA 2NWHA 1VM7A 4CVKA 1JXIA 2Q5RA 3W4SA 3H49A 4K8CA 3RT7A 3NBVA 1YHJA 1RFTA 1WYEA 4LC4A 1LIJA 3RO4A 3NL5A 3UQDA 4KALA 1E0DA 2AB8A 1LIIA 3QCZA 2PKNA 4K9IA 4C5LA 3B1NA 3ZM5A 3RQ6A 2XPCA 4C5KA 4E8ZA 2DDOA 2Y66A 4PVVA 3RPZA 5TQIA 1P3DA 3GO7A 3RQ2A 4UBEA 3EAGA 3UMOA 2ABQA 3B3LA 3B1PA 4XF6A 3LK7A 1GG4A 3QA2A 3RY7A 3IE7A 2GCAA 2HQQA 3HJ6A 4LCAA 1P31A 4N09A 2F00A 1GQQA 3PYZA 4E84A 1W7KA 2JFGA 2AJPA 3B1RA 4C13A 2Y1OA 3HYOA 1U2XA 1KYHA 4JJPA 3N2AA 3NCAA 3HN7A 1LHPA 3VAQA 3HPDA 3NRSA 1LIOA 3DRWA 4B8SA 4KANA 2I6BA 1YGKA 1V19A 4CVLA 2AJRA 4E69A 3K5WA 1TZ6A 2C4EA 3RRFA 3RSQA 3RTCA 4XCKA 4B8RA 2VARA 4U7XA 5A5FA 3EWMA 1JXHA 1J6UA 2AX3A 3PZSA 5F0ZA 4JKSA 2Y67A 3CQDA 3RTDA 3QAIA 3KZHA 4EUMA 2DDWA 1JBWA 2JG1A 3RRJA 4E8WA 1YGJA 2WTZA 4EOHA 3IBQA 2JFFA 1TYYA 3RS9A 3GO6A 4KAHA 4DC3A 3Q1YA 3RU2A 2AWDA 3NC9A 2C49A 3NL6A 5F11A 2X5OA 1O5ZA 1E8CA 3RTGA 3MBHA 3BGKA 3HICA 2UUOA 4YL5A 4XF7A 4XDAA 3B1QA 3NM1A 4N08A 1DGMA 3RQQA 4QDIA 4BUCA 3UAGA 1V1SA 3B1OA 2UUPA 1ESQA 2UAGA 3RREA 1RKSA 2A9ZA 3UQ6A 3RQHA 2VTEA 4LBXA 2YXUA 2PKMA 5EYNA 3VASA 3NL2A 4UAGA 1EKKA 3RTBA 1JBVA 1V1BA 2AM2A 2F7KA 2GCBA 2HW1A 2VORA 1VI9A 1UA4A 5CM5A 3K9EA 3NBWA 3H74A 1TD2A 3NM3A 5C3ZA 3ZS7A 2R3BA 4GM6A 4E3AA 3RS8A 2WJPA 2ABSA 3UMPA 5CGEA 4DU5A 3Q92A 4E8YA 2QHPA 4O1GA 2PKFA 1LHRA 4JKUA 1RFVA 3LKIA 5BYCA 1V1AA 1GQYA 3MBJA 4KADA 1C3QA 1VK4A 1BX4A 4O1LA 3RTAA 2FV7A 4K93A 5C40A 3LJSA 1TZ3A 4BUBA 4C5NA 3UQ9A 4YWRA 3RM5A 1GQTA 3LOOA 2VTDA 2Y68A 3NC2A
chains in the Genus database with same CATH topology
4N09A 2JGVA 3DZVA 3KEUA 5BYDA 1V1SA 4E84A 3B1OA 3KD6A 1GC5A 3N1CA 2YXTA 2AJPA 2DCNA 1ESQA 3B1RA 4C5JA 2AFBA 3HYOA 1RKSA 2A9ZA 1U2XA 3RPHA 1RK2A 1KYHA 4JJPA 1RKDA 2A9YA 1LIKA 3RQHA 3FHXA 2I6AA 4LBXA 3NCAA 4LBGA 1LHPA 2YXUA 2PKMA 5EYNA 3VASA 3UBOA 3RQ5A 3NL2A 3VAQA 1EKKA 3RSFA 4S1IB 3HPDA 2DDMA 3RTBA 1L2LA 1LIOA 3DRWA 4B8SA 3KTNA 3RSGA 3GBUA 5EY7A 4KANA 2I6BA 2QCVA 2XTBA 4K8KA 1V1BA 2F7KA 2HW1A 1VI9A 1YGKA 4EBUA 1V19A 3RSSA 1UA4A 2AJRA 3K9EA 3I3YA 5CM5A 4E69A 3NBWA 5COJA 2AA0A 3RQ8A 2HLZA 3IQ0A 3K5WA 1TZ6A 5BYFA 5BYEA 2C4EA 3H74A 1TD2A 3JULA 3NM3A 3RRFA 3RT9A 5C3ZA 3IKHA 3IN1A 5TRWA 3ZS7A 2R3BA 3RSQA 1EKQA 3OTXA 2NWHA 1VM7A 3RTCA 4XCKA 2JG5A 1JXIA 4B8RA 2VARA 4U7XA 2Q5RA 4GM6A 5B6AA 3EWMA 1JXHA 1UB0A 4E3AA 3RS8A 5C41A 2ABSA 2AX3A 3PZSA 4EN4A 5F0ZA 3RREA 4JKSA 3RTEA 3CQDA 3IH0A 3W4SA 3UMPA 3FHYA 3H49A 3RTDA 5CGEA 3QAIA 4C5MA 3KZHA 2PKKA 4K8CA 4S1HA 3RT7A 3Q92A 3NBVA 4DU5A 1YHJA 4E8YA 1RFTA 1WYEA 2DDWA 3RRBA 4LC4A 4EUMA 2QHPA 4O1GA 1LIJA 2JG1A 1LHRA 2PKFA 4JKUA 2V78A 4S1MA 3RO4A 3NL5A 3RRJA 4E8WA 3UQ6A 1YGJA 4S1IA 4KALA 1RFVA 3UQDA 2AB8A 1LIIA 3PL2A 4EOHA 3IBQA 1TYYA 3LKIA 2PKNA 2RBCA 4K9IA 3RS9A 1V1AA 4X8FA 3RU3A 4C5LA 5BYCA 3GO6A 4KAHA 4DC3A 3B1NA 3BF5A 3Q1YA 3RQ6A 3MBJA 4KADA 1C3QA 3RU2A 2AWDA 1VK4A 3NC9A 2C49A 1BX4A 3NL6A 4C5KA 4E8ZA 5F11A 2DDOA 4K8TA 4O1LA 3RTAA 3UQEA 4PVVA 2FV7A 4K93A 2R3EA 5CGAA 3RPZA 4WJMA 1ESJA 4K8PA 3LHXA 4K9CA 5C40A 3LJSA 5TQIA 3RTGA 1TZ3A 4C5NA 3MBHA 3NL3A 3GO7A 3RQ2A 4UBEA 1RFUA 3BGKA 3UQ9A 3UMOA 4YWRA 5C3YA 2ABQA 3B3LA 4KBEA 3B1PA 4XF6A 3RQXA 3HICA 2F02A 4YL5A 4XF7A 1RKAA 3QA2A 3RY7A 4XDAA 3IE7A 3RM5A 1GQTA 2I5BA 3LOOA 2HQQA 3B1QA 3HJ6A 3NM1A 4N08A 4LCAA 3NC2A 1DGMA 3RQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N09 A;  2JGV A;  3DZV A;  3KEU A;  5BYD A;  1V1S A;  4E84 A;  3B1O A;  3KD6 A;  1GC5 A;  3N1C A;  2YXT A;  2AJP A;  2DCN A;  1ESQ A;  3B1R A;  4C5J A;  2AFB A;  3HYO A;  1RKS A;  2A9Z A;  1U2X A;  3RPH A;  1RK2 A;  1KYH A;  4JJP A;  1RKD A;  2A9Y A;  1LIK A;  3RQH A;  3FHX A;  2I6A A;  4LBX A;  3NCA A;  4LBG A;  1LHP A;  2YXU A;  2PKM A;  5EYN A;  3VAS A;  3UBO A;  3RQ5 A;  3NL2 A;  3VAQ A;  1EKK A;  3RSF A;  4S1I B;  3HPD A;  2DDM A;  3RTB A;  1L2L A;  1LIO A;  3DRW A;  4B8S A;  3KTN A;  3RSG A;  3GBU A;  5EY7 A;  4KAN A;  2I6B A;  2QCV A;  2XTB A;  4K8K A;  1V1B A;  2F7K A;  2HW1 A;  1VI9 A;  1YGK A;  4EBU A;  1V19 A;  3RSS A;  1UA4 A;  2AJR A;  3K9E A;  3I3Y A;  5CM5 A;  4E69 A;  3NBW A;  5COJ A;  2AA0 A;  3RQ8 A;  2HLZ A;  3IQ0 A;  3K5W A;  1TZ6 A;  5BYF A;  5BYE A;  2C4E A;  3H74 A;  1TD2 A;  3JUL A;  3NM3 A;  3RRF A;  3RT9 A;  5C3Z A;  3IKH A;  3IN1 A;  5TRW A;  3ZS7 A;  2R3B A;  3RSQ A;  1EKQ A;  3OTX A;  2NWH A;  1VM7 A;  3RTC A;  4XCK A;  2JG5 A;  1JXI A;  4B8R A;  2VAR A;  4U7X A;  2Q5R A;  4GM6 A;  5B6A A;  3EWM A;  1JXH A;  1UB0 A;  4E3A A;  3RS8 A;  5C41 A;  2ABS A;  2AX3 A;  3PZS A;  4EN4 A;  5F0Z A;  3RRE A;  4JKS A;  3RTE A;  3CQD A;  3IH0 A;  3W4S A;  3UMP A;  3FHY A;  3H49 A;  3RTD A;  5CGE A;  3QAI A;  4C5M A;  3KZH A;  2PKK A;  4K8C A;  4S1H A;  3RT7 A;  3Q92 A;  3NBV A;  4DU5 A;  1YHJ A;  4E8Y A;  1RFT A;  1WYE A;  2DDW A;  3RRB A;  4LC4 A;  4EUM A;  2QHP A;  4O1G A;  1LIJ A;  2JG1 A;  1LHR A;  2PKF A;  4JKU A;  2V78 A;  4S1M A;  3RO4 A;  3NL5 A;  3RRJ A;  4E8W A;  3UQ6 A;  1YGJ A;  4S1I A;  4KAL A;  1RFV A;  3UQD A;  2AB8 A;  1LII A;  3PL2 A;  4EOH A;  3IBQ A;  1TYY A;  3LKI A;  2PKN A;  2RBC A;  4K9I A;  3RS9 A;  1V1A A;  4X8F A;  3RU3 A;  4C5L A;  5BYC A;  3GO6 A;  4KAH A;  4DC3 A;  3B1N A;  3BF5 A;  3Q1Y A;  3RQ6 A;  3MBJ A;  4KAD A;  1C3Q A;  3RU2 A;  2AWD A;  1VK4 A;  3NC9 A;  2C49 A;  1BX4 A;  3NL6 A;  4C5K A;  4E8Z A;  5F11 A;  2DDO A;  4K8T A;  4O1L A;  3RTA A;  3UQE A;  4PVV A;  2FV7 A;  4K93 A;  2R3E A;  5CGA A;  3RPZ A;  4WJM A;  1ESJ A;  4K8P A;  3LHX A;  4K9C A;  5C40 A;  3LJS A;  5TQI A;  3RTG A;  1TZ3 A;  4C5N A;  3MBH A;  3NL3 A;  3GO7 A;  3RQ2 A;  4UBE A;  1RFU A;  3BGK A;  3UQ9 A;  3UMO A;  4YWR A;  5C3Y A;  2ABQ A;  3B3L A;  4KBE A;  3B1P A;  4XF6 A;  3RQX A;  3HIC A;  2F02 A;  4YL5 A;  4XF7 A;  1RKA A;  3QA2 A;  3RY7 A;  4XDA A;  3IE7 A;  3RM5 A;  1GQT A;  2I5B A;  3LOO A;  2HQQ A;  3B1Q A;  3NM1 A;  4N08 A;  4LCA A;  3NC2 A;  1DGM A;  3RQQ A; 
#chains in the Genus database with same CATH topology
 2JGV A;  3DZV A;  2JFH A;  5BYD A;  2VOS A;  3KD6 A;  2YXT A;  2DCN A;  4C5J A;  2AFB A;  3RPH A;  2A9Y A;  4HV4 A;  2I6A A;  4LBG A;  3UBO A;  2DDM A;  3KTN A;  2QCV A;  1EEH A;  3I3Y A;  5COJ A;  3IQ0 A;  5BYF A;  3RT9 A;  3IN1 A;  2JG5 A;  5B6A A;  1UB0 A;  2GC5 A;  5C41 A;  3ZL8 A;  4EN4 A;  3RTE A;  3IH0 A;  3FHY A;  4C5M A;  2PKK A;  4S1H A;  4CVM A;  3RRB A;  1UAG A;  4S1M A;  2V78 A;  2XJA A;  4S1I A;  3PL2 A;  3RU3 A;  2RBC A;  4X8F A;  3BF5 A;  4QF5 A;  3ZM6 A;  4K8T A;  4C12 A;  3UQE A;  2R3E A;  5CGA A;  4WJM A;  1ESJ A;  4K8P A;  3LHX A;  4K9C A;  2GC6 A;  3NL3 A;  1RFU A;  5C3Y A;  4KBE A;  3RQX A;  2F02 A;  1RKA A;  2AM1 A;  2I5B A;  3KEU A;  3N1C A;  1GC5 A;  1RK2 A;  1RKD A;  1LIK A;  3FHX A;  3RQ5 A;  4ZIY A;  3RSF A;  4S1I B;  1L2L A;  3RSG A;  3GBU A;  1W78 A;  5EY7 A;  2XTB A;  4K8K A;  5A5E A;  4EBU A;  3RSS A;  3RQ8 A;  2AA0 A;  2HLZ A;  5BYE A;  3JUL A;  3IKH A;  1FGS A;  5TRW A;  1EKQ A;  3OTX A;  2NWH A;  1VM7 A;  4CVK A;  1JXI A;  2Q5R A;  3W4S A;  3H49 A;  4K8C A;  3RT7 A;  3NBV A;  1YHJ A;  1RFT A;  1WYE A;  4LC4 A;  1LIJ A;  3RO4 A;  3NL5 A;  3UQD A;  4KAL A;  1E0D A;  2AB8 A;  1LII A;  3QCZ A;  2PKN A;  4K9I A;  4C5L A;  3B1N A;  3ZM5 A;  3RQ6 A;  2XPC A;  4C5K A;  4E8Z A;  2DDO A;  2Y66 A;  4PVV A;  3RPZ A;  5TQI A;  1P3D A;  3GO7 A;  3RQ2 A;  4UBE A;  3EAG A;  3UMO A;  2ABQ A;  3B3L A;  3B1P A;  4XF6 A;  3LK7 A;  1GG4 A;  3QA2 A;  3RY7 A;  3IE7 A;  2GCA A;  2HQQ A;  3HJ6 A;  4LCA A;  1P31 A;  4N09 A;  2F00 A;  1GQQ A;  3PYZ A;  4E84 A;  1W7K A;  2JFG A;  2AJP A;  3B1R A;  4C13 A;  2Y1O A;  3HYO A;  1U2X A;  1KYH A;  4JJP A;  3N2A A;  3NCA A;  3HN7 A;  1LHP A;  3VAQ A;  3HPD A;  3NRS A;  1LIO A;  3DRW A;  4B8S A;  4KAN A;  2I6B A;  1YGK A;  1V19 A;  4CVL A;  2AJR A;  4E69 A;  3K5W A;  1TZ6 A;  2C4E A;  3RRF A;  3RSQ A;  3RTC A;  4XCK A;  4B8R A;  2VAR A;  4U7X A;  5A5F A;  3EWM A;  1JXH A;  1J6U A;  2AX3 A;  3PZS A;  5F0Z A;  4JKS A;  2Y67 A;  3CQD A;  3RTD A;  3QAI A;  3KZH A;  4EUM A;  2DDW A;  1JBW A;  2JG1 A;  3RRJ A;  4E8W A;  1YGJ A;  2WTZ A;  4EOH A;  3IBQ A;  2JFF A;  1TYY A;  3RS9 A;  3GO6 A;  4KAH A;  4DC3 A;  3Q1Y A;  3RU2 A;  2AWD A;  3NC9 A;  2C49 A;  3NL6 A;  5F11 A;  2X5O A;  1O5Z A;  1E8C A;  3RTG A;  3MBH A;  3BGK A;  3HIC A;  2UUO A;  4YL5 A;  4XF7 A;  4XDA A;  3B1Q A;  3NM1 A;  4N08 A;  1DGM A;  3RQQ A;  4QDI A;  4BUC A;  3UAG A;  1V1S A;  3B1O A;  2UUP A;  1ESQ A;  2UAG A;  3RRE A;  1RKS A;  2A9Z A;  3UQ6 A;  3RQH A;  2VTE A;  4LBX A;  2YXU A;  2PKM A;  5EYN A;  3VAS A;  3NL2 A;  4UAG A;  1EKK A;  3RTB A;  1JBV A;  1V1B A;  2AM2 A;  2F7K A;  2GCB A;  2HW1 A;  2VOR A;  1VI9 A;  1UA4 A;  5CM5 A;  3K9E A;  3NBW A;  3H74 A;  1TD2 A;  3NM3 A;  5C3Z A;  3ZS7 A;  2R3B A;  4GM6 A;  4E3A A;  3RS8 A;  2WJP A;  2ABS A;  3UMP A;  5CGE A;  4DU5 A;  3Q92 A;  4E8Y A;  2QHP A;  4O1G A;  2PKF A;  1LHR A;  4JKU A;  1RFV A;  3LKI A;  5BYC A;  1V1A A;  1GQY A;  3MBJ A;  4KAD A;  1C3Q A;  1VK4 A;  1BX4 A;  4O1L A;  3RTA A;  2FV7 A;  4K93 A;  5C40 A;  3LJS A;  1TZ3 A;  4BUB A;  4C5N A;  3UQ9 A;  4YWR A;  3RM5 A;  1GQT A;  3LOO A;  2VTD A;  2Y68 A;  3NC2 A; 
#chains in the Genus database with same CATH homology
 4N09 A;  2JGV A;  3DZV A;  3KEU A;  5BYD A;  1V1S A;  4E84 A;  3B1O A;  3KD6 A;  1GC5 A;  3N1C A;  2YXT A;  2AJP A;  2DCN A;  1ESQ A;  3B1R A;  4C5J A;  2AFB A;  3HYO A;  1RKS A;  2A9Z A;  1U2X A;  3RPH A;  1RK2 A;  1KYH A;  4JJP A;  1RKD A;  2A9Y A;  1LIK A;  3RQH A;  3FHX A;  2I6A A;  4LBX A;  3NCA A;  4LBG A;  1LHP A;  2YXU A;  2PKM A;  5EYN A;  3VAS A;  3UBO A;  3RQ5 A;  3NL2 A;  3VAQ A;  1EKK A;  3RSF A;  4S1I B;  3HPD A;  2DDM A;  3RTB A;  1L2L A;  1LIO A;  3DRW A;  4B8S A;  3KTN A;  3RSG A;  3GBU A;  5EY7 A;  4KAN A;  2I6B A;  2QCV A;  2XTB A;  4K8K A;  1V1B A;  2F7K A;  2HW1 A;  1VI9 A;  1YGK A;  4EBU A;  1V19 A;  3RSS A;  1UA4 A;  2AJR A;  3K9E A;  3I3Y A;  5CM5 A;  4E69 A;  3NBW A;  5COJ A;  2AA0 A;  3RQ8 A;  2HLZ A;  3IQ0 A;  3K5W A;  1TZ6 A;  5BYF A;  5BYE A;  2C4E A;  3H74 A;  1TD2 A;  3JUL A;  3NM3 A;  3RRF A;  3RT9 A;  5C3Z A;  3IKH A;  3IN1 A;  5TRW A;  3ZS7 A;  2R3B A;  3RSQ A;  1EKQ A;  3OTX A;  2NWH A;  1VM7 A;  3RTC A;  4XCK A;  2JG5 A;  1JXI A;  4B8R A;  2VAR A;  4U7X A;  2Q5R A;  4GM6 A;  5B6A A;  3EWM A;  1JXH A;  1UB0 A;  4E3A A;  3RS8 A;  5C41 A;  2ABS A;  2AX3 A;  3PZS A;  4EN4 A;  5F0Z A;  3RRE A;  4JKS A;  3RTE A;  3CQD A;  3IH0 A;  3W4S A;  3UMP A;  3FHY A;  3H49 A;  3RTD A;  5CGE A;  3QAI A;  4C5M A;  3KZH A;  2PKK A;  4K8C A;  4S1H A;  3RT7 A;  3Q92 A;  3NBV A;  4DU5 A;  1YHJ A;  4E8Y A;  1RFT A;  1WYE A;  2DDW A;  3RRB A;  4LC4 A;  4EUM A;  2QHP A;  4O1G A;  1LIJ A;  2JG1 A;  1LHR A;  2PKF A;  4JKU A;  2V78 A;  4S1M A;  3RO4 A;  3NL5 A;  3RRJ A;  4E8W A;  3UQ6 A;  1YGJ A;  4S1I A;  4KAL A;  1RFV A;  3UQD A;  2AB8 A;  1LII A;  3PL2 A;  4EOH A;  3IBQ A;  1TYY A;  3LKI A;  2PKN A;  2RBC A;  4K9I A;  3RS9 A;  1V1A A;  4X8F A;  3RU3 A;  4C5L A;  5BYC A;  3GO6 A;  4KAH A;  4DC3 A;  3B1N A;  3BF5 A;  3Q1Y A;  3RQ6 A;  3MBJ A;  4KAD A;  1C3Q A;  3RU2 A;  2AWD A;  1VK4 A;  3NC9 A;  2C49 A;  1BX4 A;  3NL6 A;  4C5K A;  4E8Z A;  5F11 A;  2DDO A;  4K8T A;  4O1L A;  3RTA A;  3UQE A;  4PVV A;  2FV7 A;  4K93 A;  2R3E A;  5CGA A;  3RPZ A;  4WJM A;  1ESJ A;  4K8P A;  3LHX A;  4K9C A;  5C40 A;  3LJS A;  5TQI A;  3RTG A;  1TZ3 A;  4C5N A;  3MBH A;  3NL3 A;  3GO7 A;  3RQ2 A;  4UBE A;  1RFU A;  3BGK A;  3UQ9 A;  3UMO A;  4YWR A;  5C3Y A;  2ABQ A;  3B3L A;  4KBE A;  3B1P A;  4XF6 A;  3RQX A;  3HIC A;  2F02 A;  4YL5 A;  4XF7 A;  1RKA A;  3QA2 A;  3RY7 A;  4XDA A;  3IE7 A;  3RM5 A;  1GQT A;  2I5B A;  3LOO A;  2HQQ A;  3B1Q A;  3HJ6 A;  3NM1 A;  4N08 A;  4LCA A;  3NC2 A;  1DGM A;  3RQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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