The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
161
|
sequence length |
539
|
structure length |
510
|
Chain Sequence |
KFSKEQFDYSLYLVTDSGMIPEGKTLYGQVEAGLQNGVTLVQIREKDADTKFFIEEALQIKELCHAHNVPLIINDRIDVAMAIGADGIHVGQDDMPIPMIRKLVGPDMVIGWSVGFPEEVDELSKMGPDMVDYIGVGTLFPTLTKKNPMGTAGAIRVLDALERNNAHWCRTVGIGGLHPDNIERVLYQCVSSNGKRSLDGICVVSDIIASLDAAKSTKILRGLIDKTDYKFVNIGLSTKNSLTTTDEIQSIISNTLKARPLVQHITNKVHQNFGANVTLALGSSPIMSEIQSEVNDLAAIPHATLLLNTGSVAPPEMLKAAIRAYNDVKRPIVFDPVGATETRLLLNNKLLTFGQFSCIKGNSSEILGLAELSNELLIQATKIVAFKYKTVAVCTGEFDFIADGTIEGKYSLSKGTNGTSVEDIPCVAVEAGPIGCSLGSTIACMIGGQPSEGNLFHAVVAGVMLYKAAGKIASEKCNGSGSFQVELIDALYRLTRENTPVTWAPKLTHT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Domain Organization in Candida glabrata THI6, a Bifunctional Enzyme Required for Thiamin Biosynthesis in Eukaryotes .
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Candida glabrata
|
| molecule keywords |
Thiamine biosynthetic bifunctional enzyme
|
| total genus |
161
|
| structure length |
510
|
| sequence length |
539
|
| chains with identical sequence |
B, C, D, E, F
|
| ec nomenclature |
ec
2.5.1.3: Thiamine phosphate synthase. |
| pdb deposition date | 2010-06-21 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02110 | HK | Hydroxyethylthiazole kinase family |
| A | PF02581 | TMP-TENI | Thiamine monophosphate synthase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | ||
| Alpha Beta | 3-Layer(aba) Sandwich | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase |
