4B4NA

Cpsf6 defines a conserved capsid interface that modulates hiv-1 replication
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
136
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cpsf6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication.
pubmed doi rcsb
molecule tags Viral protein/rna binding protein
source organism Human immunodeficiency virus 1
molecule keywords GAG PROTEIN
total genus 50
structure length 136
sequence length 146
ec nomenclature
pdb deposition date 2012-07-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4b4nA00
4XFXA 2X2DD 4XROA 4LQWC 2WLVA 1M9EC 2M8NA 3H47A 1U7KA 1M9FC 4E91A 2XGUA 3H4EA 2PWMA 2V4XA 4HTWA 1L6NA 4XFYA 2LF4A 4DGAC 4PH0A 2PWOA 2XGYA 1G03A 3MGEA 3BP9A 2KGFA 1EM9A 4PH2A 4DGEC 5HGNA 2X82A 5HGMA 5JPAA 2XGVA 3NTEA 4XRQA 5HGLA 2GONA 5HGOA 1GWPA 1M9DC 1P7NA 1EIAA 1M9XC 2M8PA 2JPRA 2Y4ZA 4QNBA 4U0EA 4U0AA 2GOLB 2PXRC 4B4NA 4INBA 1D1DA 1E6JP 1M9CC 4U0BA 1M9YC 4PH3A 2M8LA 2WLVB 4NX4C 4U0FA 3P05A 4U0CA 4WYMA 2EIAA 4J93A 5HGKA 1AFVA 4XFZA 1AK4C 1QRJA 4U0DA 4E92A 2XDEA 2X83A
chains in the Genus database with same CATH superfamily
4XFXA 2X2DD 4XROA 4LQWC 2WLVA 1M9EC 2M8NA 3H47A 1U7KA 1M9FC 4E91A 2XGUA 3H4EA 2PWMA 2V4XA 4HTWA 1L6NA 4XFYA 2LF4A 4DGAC 4PH0A 2PWOA 2XGYA 1G03A 3MGEA 3BP9A 2KGFA 1EM9A 4PH2A 4DGEC 5HGNA 2X82A 5HGMA 5JPAA 2XGVA 3NTEA 4XRQA 5HGLA 2GONA 5HGOA 1GWPA 1M9DC 1P7NA 1EIAA 1M9XC 2M8PA 2JPRA 2Y4ZA 4QNBA 4U0EA 4U0AA 2GOLB 2PXRC 4B4NA 4INBA 1D1DA 1E6JP 1M9CC 4U0BA 1M9YC 4PH3A 2M8LA 2WLVB 4NX4C 4U0FA 3P05A 4U0CA 4WYMA 2EIAA 4J93A 5HGKA 1AFVA 4XFZA 1AK4C 1QRJA 4U0DA 4E92A 2XDEA 2X83A
chains in the Genus database with same CATH topology
4XFXA 2X2DD 4XROA 4LQWC 2WLVA 1M9EC 2M8NA 3H47A 1U7KA 1M9FC 4E91A 2XGUA 3H4EA 2PWMA 2V4XA 4HTWA 1L6NA 4XFYA 2LF4A 4DGAC 4PH0A 2PWOA 2XGYA 1G03A 3MGEA 3BP9A 2KGFA 1EM9A 4PH2A 4DGEC 5HGNA 2X82A 5HGMA 5JPAA 2XGVA 3NTEA 4XRQA 5HGLA 2GONA 5HGOA 1GWPA 1M9DC 1P7NA 1EIAA 1M9XC 2M8PA 2JPRA 2Y4ZA 4QNBA 4U0EA 4U0AA 2GOLB 2PXRC 4B4NA 4INBA 1D1DA 1E6JP 1M9CC 4U0BA 1M9YC 4PH3A 2M8LA 2WLVB 4NX4C 4U0FA 3P05A 4U0CA 4WYMA 2EIAA 4J93A 5HGKA 1AFVA 4XFZA 1AK4C 1QRJA 4U0DA 4E92A 2XDEA 2X83A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XFX A;  2X2D D;  4XRO A;  4LQW C;  2WLV A;  1M9E C;  2M8N A;  3H47 A;  1U7K A;  1M9F C;  4E91 A;  2XGU A;  3H4E A;  2PWM A;  2V4X A;  4HTW A;  1L6N A;  4XFY A;  2LF4 A;  4DGA C;  4PH0 A;  2PWO A;  2XGY A;  1G03 A;  3MGE A;  3BP9 A;  2KGF A;  1EM9 A;  4PH2 A;  4DGE C;  5HGN A;  2X82 A;  5HGM A;  5JPA A;  2XGV A;  3NTE A;  4XRQ A;  5HGL A;  2GON A;  5HGO A;  1GWP A;  1M9D C;  1P7N A;  1EIA A;  1M9X C;  2M8P A;  2JPR A;  2Y4Z A;  4QNB A;  4U0E A;  4U0A A;  2GOL B;  2PXR C;  4B4N A;  4INB A;  1D1D A;  1E6J P;  1M9C C;  4U0B A;  1M9Y C;  4PH3 A;  2M8L A;  2WLV B;  4NX4 C;  4U0F A;  3P05 A;  4U0C A;  4WYM A;  2EIA A;  4J93 A;  5HGK A;  1AFV A;  4XFZ A;  1AK4 C;  1QRJ A;  4U0D A;  4E92 A;  2XDE A;  2X83 A; 
#chains in the Genus database with same CATH topology
 4XFX A;  2X2D D;  4XRO A;  4LQW C;  2WLV A;  1M9E C;  2M8N A;  3H47 A;  1U7K A;  1M9F C;  4E91 A;  2XGU A;  3H4E A;  2PWM A;  2V4X A;  4HTW A;  1L6N A;  4XFY A;  2LF4 A;  4DGA C;  4PH0 A;  2PWO A;  2XGY A;  1G03 A;  3MGE A;  3BP9 A;  2KGF A;  1EM9 A;  4PH2 A;  4DGE C;  5HGN A;  2X82 A;  5HGM A;  5JPA A;  2XGV A;  3NTE A;  4XRQ A;  5HGL A;  2GON A;  5HGO A;  1GWP A;  1M9D C;  1P7N A;  1EIA A;  1M9X C;  2M8P A;  2JPR A;  2Y4Z A;  4QNB A;  4U0E A;  4U0A A;  2GOL B;  2PXR C;  4B4N A;  4INB A;  1D1D A;  1E6J P;  1M9C C;  4U0B A;  1M9Y C;  4PH3 A;  2M8L A;  2WLV B;  4NX4 C;  4U0F A;  3P05 A;  4U0C A;  4WYM A;  2EIA A;  4J93 A;  5HGK A;  1AFV A;  4XFZ A;  1AK4 C;  1QRJ A;  4U0D A;  4E92 A;  2XDE A;  2X83 A; 
#chains in the Genus database with same CATH homology
 4XFX A;  2X2D D;  4XRO A;  4LQW C;  2WLV A;  1M9E C;  2M8N A;  3H47 A;  1U7K A;  1M9F C;  4E91 A;  2XGU A;  3H4E A;  2PWM A;  2V4X A;  4HTW A;  1L6N A;  4XFY A;  2LF4 A;  4DGA C;  4PH0 A;  2PWO A;  2XGY A;  1G03 A;  3MGE A;  3BP9 A;  2KGF A;  1EM9 A;  4PH2 A;  4DGE C;  5HGN A;  2X82 A;  5HGM A;  5JPA A;  2XGV A;  3NTE A;  4XRQ A;  5HGL A;  2GON A;  5HGO A;  1GWP A;  1M9D C;  1P7N A;  1EIA A;  1M9X C;  2M8P A;  2JPR A;  2Y4Z A;  4QNB A;  4U0E A;  4U0A A;  2GOL B;  2PXR C;  4B4N A;  4INB A;  1D1D A;  1E6J P;  1M9C C;  4U0B A;  1M9Y C;  4PH3 A;  2M8L A;  2WLV B;  4NX4 C;  4U0F A;  3P05 A;  4U0C A;  4WYM A;  2EIA A;  4J93 A;  5HGK A;  1AFV A;  4XFZ A;  1AK4 C;  1QRJ A;  4U0D A;  4E92 A;  2XDE A;  2X83 A; 
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