4DGEC

Trimcyp cyclophilin domain from macaca mulatta: h70c mutant, hiv-1 ca(o-loop) complex
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
143
structure length
136
Chain Sequence
PIVVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPTGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Macaca mulatta
molecule keywords TRIMCyp
total genus 47
structure length 136
sequence length 143
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-01-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4dgeC00
4J93A 4XFYA 2LF4A 2V4XA 4LQWC 1GWPA 4U0CA 4E91A 4XFZA 2XDEA 4XFXA 2M8LA 2PXRC 4INBA 2PWMA 1M9CC 2KGFA 1AK4C 2PWOA 4U0EA 3BP9A 3H4EA 1QRJA 4QNBA 5HGMA 2GONA 1G03A 1P7NA 4HTWA 1E6JP 2X82A 4DGEC 5HGNA 3P05A 4XRQA 4PH0A 1AFVA 1L6NA 4NX4C 4U0FA 2XGYA 2X2DD 4XROA 4U0BA 2Y4ZA 2M8NA 2JPRA 1EM9A 1M9EC 2XGUA 1U7KA 2M8PA 4PH2A 1M9FC 2GOLB 1M9DC 1M9XC 4DGAC 1M9YC 2X83A 2WLVA 2WLVB 3MGEA 3NTEA 5HGOA 5JPAA 2EIAA 4WYMA 3H47A 4U0DA 4E92A 4PH3A 1D1DA 2XGVA 5HGKA 5HGLA 1EIAA 4U0AA 4B4NA
chains in the Genus database with same CATH superfamily
4J93A 4XFYA 2LF4A 2V4XA 4LQWC 1GWPA 4U0CA 4E91A 4XFZA 2XDEA 4XFXA 2M8LA 2PXRC 4INBA 2PWMA 1M9CC 2KGFA 1AK4C 2PWOA 4U0EA 3BP9A 3H4EA 1QRJA 4QNBA 5HGMA 2GONA 1G03A 1P7NA 4HTWA 1E6JP 2X82A 4DGEC 5HGNA 3P05A 4XRQA 4PH0A 1AFVA 1L6NA 4NX4C 4U0FA 2XGYA 2X2DD 4XROA 4U0BA 2Y4ZA 2M8NA 2JPRA 1EM9A 1M9EC 2XGUA 1U7KA 2M8PA 4PH2A 1M9FC 2GOLB 1M9DC 1M9XC 4DGAC 1M9YC 2X83A 2WLVA 2WLVB 3MGEA 3NTEA 5HGOA 5JPAA 2EIAA 4WYMA 3H47A 4U0DA 4E92A 4PH3A 1D1DA 2XGVA 5HGKA 5HGLA 1EIAA 4U0AA 4B4NA
chains in the Genus database with same CATH topology
4J93A 4XFYA 2LF4A 2V4XA 4LQWC 1GWPA 4U0CA 4E91A 4XFZA 2XDEA 4XFXA 2M8LA 2PXRC 4INBA 2PWMA 1M9CC 2KGFA 1AK4C 2PWOA 4U0EA 3BP9A 3H4EA 1QRJA 4QNBA 5HGMA 2GONA 1G03A 1P7NA 4HTWA 1E6JP 2X82A 4DGEC 5HGNA 3P05A 4XRQA 4PH0A 1AFVA 1L6NA 4NX4C 4U0FA 2XGYA 2X2DD 4XROA 4U0BA 2Y4ZA 2M8NA 2JPRA 1EM9A 1M9EC 2XGUA 1U7KA 2M8PA 4PH2A 1M9FC 2GOLB 1M9DC 1M9XC 4DGAC 1M9YC 2X83A 2WLVA 2WLVB 3MGEA 3NTEA 5HGOA 5JPAA 2EIAA 4WYMA 3H47A 4U0DA 4E92A 4PH3A 1D1DA 2XGVA 5HGKA 5HGLA 1EIAA 4U0AA 4B4NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J93 A;  4XFY A;  2LF4 A;  2V4X A;  4LQW C;  1GWP A;  4U0C A;  4E91 A;  4XFZ A;  2XDE A;  4XFX A;  2M8L A;  2PXR C;  4INB A;  2PWM A;  1M9C C;  2KGF A;  1AK4 C;  2PWO A;  4U0E A;  3BP9 A;  3H4E A;  1QRJ A;  4QNB A;  5HGM A;  2GON A;  1G03 A;  1P7N A;  4HTW A;  1E6J P;  2X82 A;  4DGE C;  5HGN A;  3P05 A;  4XRQ A;  4PH0 A;  1AFV A;  1L6N A;  4NX4 C;  4U0F A;  2XGY A;  2X2D D;  4XRO A;  4U0B A;  2Y4Z A;  2M8N A;  2JPR A;  1EM9 A;  1M9E C;  2XGU A;  1U7K A;  2M8P A;  4PH2 A;  1M9F C;  2GOL B;  1M9D C;  1M9X C;  4DGA C;  1M9Y C;  2X83 A;  2WLV A;  2WLV B;  3MGE A;  3NTE A;  5HGO A;  5JPA A;  2EIA A;  4WYM A;  3H47 A;  4U0D A;  4E92 A;  4PH3 A;  1D1D A;  2XGV A;  5HGK A;  5HGL A;  1EIA A;  4U0A A;  4B4N A; 
#chains in the Genus database with same CATH topology
 4J93 A;  4XFY A;  2LF4 A;  2V4X A;  4LQW C;  1GWP A;  4U0C A;  4E91 A;  4XFZ A;  2XDE A;  4XFX A;  2M8L A;  2PXR C;  4INB A;  2PWM A;  1M9C C;  2KGF A;  1AK4 C;  2PWO A;  4U0E A;  3BP9 A;  3H4E A;  1QRJ A;  4QNB A;  5HGM A;  2GON A;  1G03 A;  1P7N A;  4HTW A;  1E6J P;  2X82 A;  4DGE C;  5HGN A;  3P05 A;  4XRQ A;  4PH0 A;  1AFV A;  1L6N A;  4NX4 C;  4U0F A;  2XGY A;  2X2D D;  4XRO A;  4U0B A;  2Y4Z A;  2M8N A;  2JPR A;  1EM9 A;  1M9E C;  2XGU A;  1U7K A;  2M8P A;  4PH2 A;  1M9F C;  2GOL B;  1M9D C;  1M9X C;  4DGA C;  1M9Y C;  2X83 A;  2WLV A;  2WLV B;  3MGE A;  3NTE A;  5HGO A;  5JPA A;  2EIA A;  4WYM A;  3H47 A;  4U0D A;  4E92 A;  4PH3 A;  1D1D A;  2XGV A;  5HGK A;  5HGL A;  1EIA A;  4U0A A;  4B4N A; 
#chains in the Genus database with same CATH homology
 4J93 A;  4XFY A;  2LF4 A;  2V4X A;  4LQW C;  1GWP A;  4U0C A;  4E91 A;  4XFZ A;  2XDE A;  4XFX A;  2M8L A;  2PXR C;  4INB A;  2PWM A;  1M9C C;  2KGF A;  1AK4 C;  2PWO A;  4U0E A;  3BP9 A;  3H4E A;  1QRJ A;  4QNB A;  5HGM A;  2GON A;  1G03 A;  1P7N A;  4HTW A;  1E6J P;  2X82 A;  4DGE C;  5HGN A;  3P05 A;  4XRQ A;  4PH0 A;  1AFV A;  1L6N A;  4NX4 C;  4U0F A;  2XGY A;  2X2D D;  4XRO A;  4U0B A;  2Y4Z A;  2M8N A;  2JPR A;  1EM9 A;  1M9E C;  2XGU A;  1U7K A;  2M8P A;  4PH2 A;  1M9F C;  2GOL B;  1M9D C;  1M9X C;  4DGA C;  1M9Y C;  2X83 A;  2WLV A;  2WLV B;  3MGE A;  3NTE A;  5HGO A;  5JPA A;  2EIA A;  4WYM A;  3H47 A;  4U0D A;  4E92 A;  4PH3 A;  1D1D A;  2XGV A;  5HGK A;  5HGL A;  1EIA A;  4U0A A;  4B4N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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