4INBA

Crystal structure of the n-terminal domain of hiv-1 capsid in complex with benzodiazepine inhibitor
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Monitoring Binding of HIV-1 Capsid Assembly Inhibitors Using (19) F Ligand-and (15) N Protein-Based NMR and X-ray Crystallography: Early Hit Validation of a Benzodiazepine Series.
pubmed doi rcsb
molecule tags Viral protein/viral protein inhibitor
source organism Human immunodeficiency virus 1
molecule keywords Gag protein
total genus 47
structure length 146
sequence length 146
ec nomenclature
pdb deposition date 2013-01-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4inbA00
5HGLA 3H47A 4U0AA 1AK4C 2WLVB 3P05A 2X2DD 1QRJA 1P7NA 2M8NA 1U7KA 2X83A 2GOLB 2M8PA 1L6NA 1E6JP 2JPRA 1M9CC 3MGEA 4B4NA 4E91A 4PH3A 3NTEA 2KGFA 2LF4A 4U0DA 5HGMA 2XGYA 1EM9A 2X82A 2PWMA 1M9XC 2V4XA 4XFYA 4XRQA 4WYMA 2M8LA 2WLVA 1AFVA 2XDEA 4HTWA 4U0FA 1M9DC 1EIAA 5HGNA 5JPAA 4XFZA 4U0CA 3BP9A 4E92A 4U0EA 4U0BA 1M9FC 4XROA 4PH2A 2XGUA 2PWOA 2Y4ZA 1GWPA 4J93A 4DGAC 4PH0A 5HGKA 5HGOA 3H4EA 1M9EC 1D1DA 4QNBA 1M9YC 4DGEC 4INBA 4NX4C 2EIAA 4LQWC 2PXRC 4XFXA 2XGVA 2GONA 1G03A
chains in the Genus database with same CATH superfamily
5HGLA 3H47A 4U0AA 1AK4C 2WLVB 3P05A 2X2DD 1QRJA 1P7NA 2M8NA 1U7KA 2X83A 2GOLB 2M8PA 1L6NA 1E6JP 2JPRA 1M9CC 3MGEA 4B4NA 4E91A 4PH3A 3NTEA 2KGFA 2LF4A 4U0DA 5HGMA 2XGYA 1EM9A 2X82A 2PWMA 1M9XC 2V4XA 4XFYA 4XRQA 4WYMA 2M8LA 2WLVA 1AFVA 2XDEA 4HTWA 4U0FA 1M9DC 1EIAA 5HGNA 5JPAA 4XFZA 4U0CA 3BP9A 4E92A 4U0EA 4U0BA 1M9FC 4XROA 4PH2A 2XGUA 2PWOA 2Y4ZA 1GWPA 4J93A 4DGAC 4PH0A 5HGKA 5HGOA 3H4EA 1M9EC 1D1DA 4QNBA 1M9YC 4DGEC 4INBA 4NX4C 2EIAA 4LQWC 2PXRC 4XFXA 2XGVA 2GONA 1G03A
chains in the Genus database with same CATH topology
5HGLA 3H47A 4U0AA 1AK4C 2WLVB 3P05A 2X2DD 1QRJA 1P7NA 2M8NA 1U7KA 2X83A 2GOLB 2M8PA 1L6NA 1E6JP 2JPRA 1M9CC 3MGEA 4B4NA 4E91A 4PH3A 3NTEA 2KGFA 2LF4A 4U0DA 5HGMA 2XGYA 1EM9A 2X82A 2PWMA 1M9XC 2V4XA 4XFYA 4XRQA 4WYMA 2M8LA 2WLVA 1AFVA 2XDEA 4HTWA 4U0FA 1M9DC 1EIAA 5HGNA 5JPAA 4XFZA 4U0CA 3BP9A 4E92A 4U0EA 4U0BA 1M9FC 4XROA 4PH2A 2XGUA 2PWOA 2Y4ZA 1GWPA 4J93A 4DGAC 4PH0A 5HGKA 5HGOA 3H4EA 1M9EC 1D1DA 4QNBA 1M9YC 4DGEC 4INBA 4NX4C 2EIAA 4LQWC 2PXRC 4XFXA 2XGVA 2GONA 1G03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HGL A;  3H47 A;  4U0A A;  1AK4 C;  2WLV B;  3P05 A;  2X2D D;  1QRJ A;  1P7N A;  2M8N A;  1U7K A;  2X83 A;  2GOL B;  2M8P A;  1L6N A;  1E6J P;  2JPR A;  1M9C C;  3MGE A;  4B4N A;  4E91 A;  4PH3 A;  3NTE A;  2KGF A;  2LF4 A;  4U0D A;  5HGM A;  2XGY A;  1EM9 A;  2X82 A;  2PWM A;  1M9X C;  2V4X A;  4XFY A;  4XRQ A;  4WYM A;  2M8L A;  2WLV A;  1AFV A;  2XDE A;  4HTW A;  4U0F A;  1M9D C;  1EIA A;  5HGN A;  5JPA A;  4XFZ A;  4U0C A;  3BP9 A;  4E92 A;  4U0E A;  4U0B A;  1M9F C;  4XRO A;  4PH2 A;  2XGU A;  2PWO A;  2Y4Z A;  1GWP A;  4J93 A;  4DGA C;  4PH0 A;  5HGK A;  5HGO A;  3H4E A;  1M9E C;  1D1D A;  4QNB A;  1M9Y C;  4DGE C;  4INB A;  4NX4 C;  2EIA A;  4LQW C;  2PXR C;  4XFX A;  2XGV A;  2GON A;  1G03 A; 
#chains in the Genus database with same CATH topology
 5HGL A;  3H47 A;  4U0A A;  1AK4 C;  2WLV B;  3P05 A;  2X2D D;  1QRJ A;  1P7N A;  2M8N A;  1U7K A;  2X83 A;  2GOL B;  2M8P A;  1L6N A;  1E6J P;  2JPR A;  1M9C C;  3MGE A;  4B4N A;  4E91 A;  4PH3 A;  3NTE A;  2KGF A;  2LF4 A;  4U0D A;  5HGM A;  2XGY A;  1EM9 A;  2X82 A;  2PWM A;  1M9X C;  2V4X A;  4XFY A;  4XRQ A;  4WYM A;  2M8L A;  2WLV A;  1AFV A;  2XDE A;  4HTW A;  4U0F A;  1M9D C;  1EIA A;  5HGN A;  5JPA A;  4XFZ A;  4U0C A;  3BP9 A;  4E92 A;  4U0E A;  4U0B A;  1M9F C;  4XRO A;  4PH2 A;  2XGU A;  2PWO A;  2Y4Z A;  1GWP A;  4J93 A;  4DGA C;  4PH0 A;  5HGK A;  5HGO A;  3H4E A;  1M9E C;  1D1D A;  4QNB A;  1M9Y C;  4DGE C;  4INB A;  4NX4 C;  2EIA A;  4LQW C;  2PXR C;  4XFX A;  2XGV A;  2GON A;  1G03 A; 
#chains in the Genus database with same CATH homology
 5HGL A;  3H47 A;  4U0A A;  1AK4 C;  2WLV B;  3P05 A;  2X2D D;  1QRJ A;  1P7N A;  2M8N A;  1U7K A;  2X83 A;  2GOL B;  2M8P A;  1L6N A;  1E6J P;  2JPR A;  1M9C C;  3MGE A;  4B4N A;  4E91 A;  4PH3 A;  3NTE A;  2KGF A;  2LF4 A;  4U0D A;  5HGM A;  2XGY A;  1EM9 A;  2X82 A;  2PWM A;  1M9X C;  2V4X A;  4XFY A;  4XRQ A;  4WYM A;  2M8L A;  2WLV A;  1AFV A;  2XDE A;  4HTW A;  4U0F A;  1M9D C;  1EIA A;  5HGN A;  5JPA A;  4XFZ A;  4U0C A;  3BP9 A;  4E92 A;  4U0E A;  4U0B A;  1M9F C;  4XRO A;  4PH2 A;  2XGU A;  2PWO A;  2Y4Z A;  1GWP A;  4J93 A;  4DGA C;  4PH0 A;  5HGK A;  5HGO A;  3H4E A;  1M9E C;  1D1D A;  4QNB A;  1M9Y C;  4DGE C;  4INB A;  4NX4 C;  2EIA A;  4LQW C;  2PXR C;  4XFX A;  2XGV A;  2GON A;  1G03 A; 
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