4IUAA

Crystal structure of the nk2 fragment (31-290) of the mouse hepatocyte growth factor/scatter factor
Total Genus 62
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
254
structure length
254
Chain Sequence
RNTLHEFKKSAKTTLTKEDPLLKIKTKKVNSADECANRCIRNRGFTFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTANGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKTCA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of the NK2 Fragment of the mouse Hepatocyte Growth Factor/Scatter Factor
rcsb
molecule tags Hormone
source organism Mus musculus
molecule keywords Hepatocyte growth factor
total genus 62
structure length 254
sequence length 254
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2013-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 4iuaA02
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 4iuaA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4iuaA01
5CT3A 1YXEA 2HPPP 4BVWA 5CS1A 4BV7A 4Z09A 4BVCA 3HN4A 1KI0A 1GP9A 5CT1A 4UV6A 2LL3A 1NL2A 3BT1A 2QJ4A 1PK2A 1A0HA 5I25A 3HMTA 1CEBA 1URKA 1PK4A 2PF2A 1Z40A 1TPKA 4APMA 3SP8A 4BVDA 1GMOA 2DOHX 3KIVA 4Z0EA 1HPJA 4NZQA 4R1BA 5COEA 4A5TS 3K65A 1HKYA 2YILA 2DOIA 1I71A 2F83A 1HPKA 1PMLA 2KJ4A 4Z0DA 1BHTA 1NK1A 2QJ2A 1I5KA 1I8NA 2K13X 1KIVA 4CIKA 4IUAA 3LAQA 4BV5A 5EOKA 2Z8VA 3ZWZA 1GMNA 2Q8BA 5EODA 4APLA 4D3CA 4BVVA 2I9BA 3ZLEA 3HMSA 5CSQA 2HPQP 3NXPA 3MKPA 2L0SA 1CEAA 2X2ZA 2PF1A 2FEBA 2HGFA 4O03A 4HZHA 2Z8WA 3SRJA 1KDUA 4KIVA 1NL1A 2YIPA 3BT2A 5CP9A 2Q8AA 1KRNA 2Y8RA 1W8KA 5CS3A 2K51A 2J8LA 1PMKA 3U73A 2I9AA 5CS9A 4R1CA 4R19A 2SPTA 1W81A 4R1AA 3HMRA 2K4RA 3E6PL 2PK4A 5CS5A 1PKRA 2KNFA 5CT2A 4DURA 5HPGA 2J8JA 1B2IA 4Z0FA 3SRIA 2FD6A 4UAOA 2LL4M 1JFNA 2YIOA
chains in the Genus database with same CATH superfamily
5CT3A 1YXEA 2HPPP 4BVWA 5CS1A 4BV7A 4Z09A 4BVCA 3HN4A 1KI0A 1GP9A 5CT1A 4UV6A 2LL3A 1NL2A 3BT1A 2QJ4A 1PK2A 1A0HA 5I25A 3HMTA 1CEBA 1URKA 1PK4A 2PF2A 1Z40A 1TPKA 4APMA 3SP8A 4BVDA 1GMOA 2DOHX 3KIVA 4Z0EA 1HPJA 4NZQA 4R1BA 4YIVA 5COEA 4A5TS 3K65A 1HKYA 2YILA 2DOIA 1I71A 2F83A 1HPKA 1PMLA 2KJ4A 4Z0DA 1BHTA 1NK1A 2QJ2A 1I5KA 1I8NA 2K13X 1KIVA 4CIKA 4IUAA 3LAQA 4BV5A 5EOKA 2Z8VA 3ZWZA 1GMNA 2Q8BA 5EODA 4APLA 4D3CA 4BVVA 2I9BA 3ZLEA 3HMSA 5CSQA 2HPQP 3NXPA 3MKPA 2L0SA 1CEAA 2X2ZA 2PF1A 2FEBA 2HGFA 4O03A 4HZHA 2Z8WA 3SRJA 1KDUA 4KIVA 1NL1A 2YIPA 3BT2A 5CP9A 2Q8AA 1KRNA 4YIZA 2Y8RA 1W8KA 5CS3A 2K51A 2J8LA 1PMKA 3U73A 2I9AA 5CS9A 4R1CA 4R19A 2SPTA 1W81A 4R1AA 3HMRA 2K4RA 3E6PL 2PK4A 5CS5A 1PKRA 2KNFA 5CT2A 4DURA 2KL5A 5HPGA 2J8JA 1B2IA 4Z0FA 3SRIA 2FD6A 4UAOA 2LL4M 1JFNA 2YIOA
chains in the Genus database with same CATH topology
5CT3A 1YXEA 2HPPP 4BVWA 5CS1A 4BV7A 4Z09A 4BVCA 3HN4A 1KI0A 1GP9A 5CT1A 4UV6A 2LL3A 1NL2A 3BT1A 2QJ4A 1PK2A 1A0HA 5I25A 3HMTA 1CEBA 1URKA 1PK4A 2PF2A 1Z40A 1TPKA 4APMA 3SP8A 4BVDA 1GMOA 2DOHX 3KIVA 4Z0EA 1HPJA 4NZQA 4R1BA 4YIVA 5COEA 4A5TS 3K65A 1HKYA 2YILA 2DOIA 1I71A 2F83A 1HPKA 1PMLA 2KJ4A 4Z0DA 1BHTA 1NK1A 2QJ2A 1I5KA 1I8NA 2K13X 1KIVA 4CIKA 4IUAA 3LAQA 4BV5A 5EOKA 2Z8VA 3ZWZA 1GMNA 2Q8BA 5EODA 4APLA 4D3CA 4BVVA 2I9BA 3ZLEA 3HMSA 5CSQA 2HPQP 3NXPA 3MKPA 2L0SA 1CEAA 2X2ZA 2PF1A 2FEBA 2HGFA 4O03A 4HZHA 2Z8WA 3SRJA 1KDUA 4KIVA 1NL1A 2YIPA 3BT2A 5CP9A 2Q8AA 1KRNA 4YIZA 2Y8RA 1W8KA 5CS3A 2K51A 2J8LA 1PMKA 3U73A 2I9AA 5CS9A 4R1CA 4R19A 2SPTA 1W81A 4R1AA 3HMRA 2K4RA 3E6PL 2PK4A 5CS5A 1PKRA 2KNFA 5CT2A 4DURA 2KL5A 5HPGA 2J8JA 1B2IA 4Z0FA 3SRIA 2FD6A 4UAOA 2LL4M 1JFNA 2YIOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CT3 A;  1YXE A;  2HPP P;  4BVW A;  5CS1 A;  4BV7 A;  4Z09 A;  4BVC A;  3HN4 A;  1KI0 A;  1GP9 A;  5CT1 A;  4UV6 A;  2LL3 A;  1NL2 A;  3BT1 A;  2QJ4 A;  1PK2 A;  1A0H A;  5I25 A;  3HMT A;  1CEB A;  1URK A;  1PK4 A;  2PF2 A;  1Z40 A;  1TPK A;  4APM A;  3SP8 A;  4BVD A;  1GMO A;  2DOH X;  3KIV A;  4Z0E A;  1HPJ A;  4NZQ A;  4R1B A;  5COE A;  4A5T S;  3K65 A;  1HKY A;  2YIL A;  2DOI A;  1I71 A;  2F83 A;  1HPK A;  1PML A;  2KJ4 A;  4Z0D A;  1BHT A;  1NK1 A;  2QJ2 A;  1I5K A;  1I8N A;  2K13 X;  1KIV A;  4CIK A;  4IUA A;  3LAQ A;  4BV5 A;  5EOK A;  2Z8V A;  3ZWZ A;  1GMN A;  2Q8B A;  5EOD A;  4APL A;  4D3C A;  4BVV A;  2I9B A;  3ZLE A;  3HMS A;  5CSQ A;  2HPQ P;  3NXP A;  3MKP A;  2L0S A;  1CEA A;  2X2Z A;  2PF1 A;  2FEB A;  2HGF A;  4O03 A;  4HZH A;  2Z8W A;  3SRJ A;  1KDU A;  4KIV A;  1NL1 A;  2YIP A;  3BT2 A;  5CP9 A;  2Q8A A;  1KRN A;  2Y8R A;  1W8K A;  5CS3 A;  2K51 A;  2J8L A;  1PMK A;  3U73 A;  2I9A A;  5CS9 A;  4R1C A;  4R19 A;  2SPT A;  1W81 A;  4R1A A;  3HMR A;  2K4R A;  3E6P L;  2PK4 A;  5CS5 A;  1PKR A;  2KNF A;  5CT2 A;  4DUR A;  5HPG A;  2J8J A;  1B2I A;  4Z0F A;  3SRI A;  2FD6 A;  4UAO A;  2LL4 M;  1JFN A;  2YIO A; 
#chains in the Genus database with same CATH topology
 5CT3 A;  1YXE A;  2HPP P;  4BVW A;  5CS1 A;  4BV7 A;  4Z09 A;  4BVC A;  3HN4 A;  1KI0 A;  1GP9 A;  5CT1 A;  4UV6 A;  2LL3 A;  1NL2 A;  3BT1 A;  2QJ4 A;  1PK2 A;  1A0H A;  5I25 A;  3HMT A;  1CEB A;  1URK A;  1PK4 A;  2PF2 A;  1Z40 A;  1TPK A;  4APM A;  3SP8 A;  4BVD A;  1GMO A;  2DOH X;  3KIV A;  4Z0E A;  1HPJ A;  4NZQ A;  4R1B A;  4YIV A;  5COE A;  4A5T S;  3K65 A;  1HKY A;  2YIL A;  2DOI A;  1I71 A;  2F83 A;  1HPK A;  1PML A;  2KJ4 A;  4Z0D A;  1BHT A;  1NK1 A;  2QJ2 A;  1I5K A;  1I8N A;  2K13 X;  1KIV A;  4CIK A;  4IUA A;  3LAQ A;  4BV5 A;  5EOK A;  2Z8V A;  3ZWZ A;  1GMN A;  2Q8B A;  5EOD A;  4APL A;  4D3C A;  4BVV A;  2I9B A;  3ZLE A;  3HMS A;  5CSQ A;  2HPQ P;  3NXP A;  3MKP A;  2L0S A;  1CEA A;  2X2Z A;  2PF1 A;  2FEB A;  2HGF A;  4O03 A;  4HZH A;  2Z8W A;  3SRJ A;  1KDU A;  4KIV A;  1NL1 A;  2YIP A;  3BT2 A;  5CP9 A;  2Q8A A;  1KRN A;  4YIZ A;  2Y8R A;  1W8K A;  5CS3 A;  2K51 A;  2J8L A;  1PMK A;  3U73 A;  2I9A A;  5CS9 A;  4R1C A;  4R19 A;  2SPT A;  1W81 A;  4R1A A;  3HMR A;  2K4R A;  3E6P L;  2PK4 A;  5CS5 A;  1PKR A;  2KNF A;  5CT2 A;  4DUR A;  2KL5 A;  5HPG A;  2J8J A;  1B2I A;  4Z0F A;  3SRI A;  2FD6 A;  4UAO A;  2LL4 M;  1JFN A;  2YIO A; 
#chains in the Genus database with same CATH homology
 5CT3 A;  1YXE A;  2HPP P;  4BVW A;  5CS1 A;  4BV7 A;  4Z09 A;  4BVC A;  3HN4 A;  1KI0 A;  1GP9 A;  5CT1 A;  4UV6 A;  2LL3 A;  1NL2 A;  3BT1 A;  2QJ4 A;  1PK2 A;  1A0H A;  5I25 A;  3HMT A;  1CEB A;  1URK A;  1PK4 A;  2PF2 A;  1Z40 A;  1TPK A;  4APM A;  3SP8 A;  4BVD A;  1GMO A;  2DOH X;  3KIV A;  4Z0E A;  1HPJ A;  4NZQ A;  4R1B A;  4YIV A;  5COE A;  4A5T S;  3K65 A;  1HKY A;  2YIL A;  2DOI A;  1I71 A;  2F83 A;  1HPK A;  1PML A;  2KJ4 A;  4Z0D A;  1BHT A;  1NK1 A;  2QJ2 A;  1I5K A;  1I8N A;  2K13 X;  1KIV A;  4CIK A;  4IUA A;  3LAQ A;  4BV5 A;  5EOK A;  2Z8V A;  3ZWZ A;  1GMN A;  2Q8B A;  5EOD A;  4APL A;  4D3C A;  4BVV A;  2I9B A;  3ZLE A;  3HMS A;  5CSQ A;  2HPQ P;  3NXP A;  3MKP A;  2L0S A;  1CEA A;  2X2Z A;  2PF1 A;  2FEB A;  2HGF A;  4O03 A;  4HZH A;  2Z8W A;  3SRJ A;  1KDU A;  4KIV A;  1NL1 A;  2YIP A;  3BT2 A;  5CP9 A;  2Q8A A;  1KRN A;  4YIZ A;  2Y8R A;  1W8K A;  5CS3 A;  2K51 A;  2J8L A;  1PMK A;  3U73 A;  2I9A A;  5CS9 A;  4R1C A;  4R19 A;  2SPT A;  1W81 A;  4R1A A;  3HMR A;  2K4R A;  3E6P L;  2PK4 A;  5CS5 A;  1PKR A;  2KNF A;  5CT2 A;  4DUR A;  2KL5 A;  5HPG A;  2J8J A;  1B2I A;  4Z0F A;  3SRI A;  2FD6 A;  4UAO A;  2LL4 M;  1JFN A;  2YIO A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...