4IUAA

Crystal structure of the nk2 fragment (31-290) of the mouse hepatocyte growth factor/scatter factor
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
254
structure length
254
Chain Sequence
RNTLHEFKKSAKTTLTKEDPLLKIKTKKVNSADECANRCIRNRGFTFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTANGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKTCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
source organism Mus musculus
publication title Crystal Structure of the NK2 Fragment of the mouse Hepatocyte Growth Factor/Scatter Factor
rcsb
molecule keywords Hepatocyte growth factor
total genus 62
structure length 254
sequence length 254
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2013-01-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 4iuaA02
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 4iuaA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4iuaA01
3SRIA 4UV6A 5CS9A 3KIVA 4R19A 1PKRA 1HPJA 2HGFA 3U73A 4APLA 2F83A 2HPQP 2K4RA 2Q8BA 3SP8A 4BVDA 1PK4A 1B2IA 2X2ZA 4BV7A 4BVCA 1CEBA 2Q8AA 3HMRA 3E6PL 1PMKA 4Z09A 5CT1A 2YIOA 2I9BA 4Z0EA 1GMNA 3HN4A 5I25A 1KI0A 4BVVA 4BVWA 1KDUA 2QJ2A 2YILA 2K51A 2SPTA 5CT2A 5EOKA 5CS3A 2DOIA 4Z0FA 1Z40A 2LL3A 1W81A 1I5KA 3LAQA 2Z8WA 1GP9A 1I71A 4D3CA 4O03A 3BT1A 1NK1A 4KIVA 4UAOA 5CS1A 2HPPP 1CEAA 1GMOA 1HKYA 4A5TS 1NL1A 2J8LA 1TPKA 2L0SA 1PMLA 3ZWZA 4HZHA 3HMSA 2LL4M 4R1AA 4R1BA 3MKPA 2PF2A 3HMTA 2QJ4A 2Z8VA 3NXPA 1JFNA 5CT3A 4DURA 4APMA 1KRNA 1KIVA 1YXEA 1A0HA 1URKA 1I8NA 5EODA 4CIKA 5HPGA 2KJ4A 2DOHX 4BV5A 2Y8RA 1BHTA 2KNFA 5COEA 4NZQA 2PF1A 3K65A 1W8KA 4IUAA 2YIPA 5CS5A 3SRJA 1NL2A 5CSQA 2J8JA 2PK4A 1PK2A 5CP9A 4R1CA 2K13X 3BT2A 2FEBA 4Z0DA 2I9AA 3ZLEA 2FD6A 1HPKA
chains in the Genus database with same CATH superfamily
3SRIA 4UV6A 5CS9A 3KIVA 4R19A 1PKRA 1HPJA 2HGFA 3U73A 4APLA 2F83A 2HPQP 2K4RA 4YIVA 2Q8BA 3SP8A 4BVDA 1PK4A 1B2IA 2X2ZA 4BV7A 4BVCA 1CEBA 2Q8AA 3HMRA 3E6PL 1PMKA 4YIZA 4Z09A 5CT1A 2YIOA 2I9BA 4Z0EA 1GMNA 3HN4A 5I25A 1KI0A 4BVVA 4BVWA 1KDUA 2QJ2A 2YILA 2K51A 2SPTA 5CT2A 5EOKA 5CS3A 2DOIA 4Z0FA 1Z40A 2LL3A 1W81A 1I5KA 3LAQA 2Z8WA 1GP9A 1I71A 4D3CA 4O03A 3BT1A 1NK1A 4KIVA 4UAOA 5CS1A 2HPPP 1CEAA 1GMOA 1HKYA 4A5TS 1NL1A 2J8LA 1TPKA 2L0SA 1PMLA 3ZWZA 4HZHA 3HMSA 2LL4M 4R1AA 4R1BA 3MKPA 2PF2A 3HMTA 2QJ4A 2Z8VA 3NXPA 1JFNA 5CT3A 4DURA 4APMA 1KRNA 1KIVA 1YXEA 1A0HA 1URKA 1I8NA 5EODA 4CIKA 5HPGA 2KJ4A 2DOHX 4BV5A 2Y8RA 1BHTA 2KNFA 5COEA 4NZQA 2PF1A 3K65A 1W8KA 2KL5A 4IUAA 2YIPA 5CS5A 3SRJA 1NL2A 5CSQA 2J8JA 2PK4A 1PK2A 5CP9A 4R1CA 2K13X 3BT2A 2FEBA 4Z0DA 2I9AA 3ZLEA 2FD6A 1HPKA
chains in the Genus database with same CATH topology
3SRIA 4UV6A 5CS9A 3KIVA 4R19A 1PKRA 1HPJA 2HGFA 3U73A 4APLA 2F83A 2HPQP 2K4RA 4YIVA 2Q8BA 3SP8A 4BVDA 1PK4A 1B2IA 2X2ZA 4BV7A 4BVCA 1CEBA 2Q8AA 3HMRA 3E6PL 1PMKA 4YIZA 4Z09A 5CT1A 2YIOA 2I9BA 4Z0EA 1GMNA 3HN4A 5I25A 1KI0A 4BVVA 4BVWA 1KDUA 2QJ2A 2YILA 2K51A 2SPTA 5CT2A 5EOKA 5CS3A 2DOIA 4Z0FA 1Z40A 2LL3A 1W81A 1I5KA 3LAQA 2Z8WA 1GP9A 1I71A 4D3CA 4O03A 3BT1A 1NK1A 4KIVA 4UAOA 5CS1A 2HPPP 1CEAA 1GMOA 1HKYA 4A5TS 1NL1A 2J8LA 1TPKA 2L0SA 1PMLA 3ZWZA 4HZHA 3HMSA 2LL4M 4R1AA 4R1BA 3MKPA 2PF2A 3HMTA 2QJ4A 2Z8VA 3NXPA 1JFNA 5CT3A 4DURA 4APMA 1KRNA 1KIVA 1YXEA 1A0HA 1URKA 1I8NA 5EODA 4CIKA 5HPGA 2KJ4A 2DOHX 4BV5A 2Y8RA 1BHTA 2KNFA 5COEA 4NZQA 2PF1A 3K65A 1W8KA 2KL5A 4IUAA 2YIPA 5CS5A 3SRJA 1NL2A 5CSQA 2J8JA 2PK4A 1PK2A 5CP9A 4R1CA 2K13X 3BT2A 2FEBA 4Z0DA 2I9AA 3ZLEA 2FD6A 1HPKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SRI A;  4UV6 A;  5CS9 A;  3KIV A;  4R19 A;  1PKR A;  1HPJ A;  2HGF A;  3U73 A;  4APL A;  2F83 A;  2HPQ P;  2K4R A;  2Q8B A;  3SP8 A;  4BVD A;  1PK4 A;  1B2I A;  2X2Z A;  4BV7 A;  4BVC A;  1CEB A;  2Q8A A;  3HMR A;  3E6P L;  1PMK A;  4Z09 A;  5CT1 A;  2YIO A;  2I9B A;  4Z0E A;  1GMN A;  3HN4 A;  5I25 A;  1KI0 A;  4BVV A;  4BVW A;  1KDU A;  2QJ2 A;  2YIL A;  2K51 A;  2SPT A;  5CT2 A;  5EOK A;  5CS3 A;  2DOI A;  4Z0F A;  1Z40 A;  2LL3 A;  1W81 A;  1I5K A;  3LAQ A;  2Z8W A;  1GP9 A;  1I71 A;  4D3C A;  4O03 A;  3BT1 A;  1NK1 A;  4KIV A;  4UAO A;  5CS1 A;  2HPP P;  1CEA A;  1GMO A;  1HKY A;  4A5T S;  1NL1 A;  2J8L A;  1TPK A;  2L0S A;  1PML A;  3ZWZ A;  4HZH A;  3HMS A;  2LL4 M;  4R1A A;  4R1B A;  3MKP A;  2PF2 A;  3HMT A;  2QJ4 A;  2Z8V A;  3NXP A;  1JFN A;  5CT3 A;  4DUR A;  4APM A;  1KRN A;  1KIV A;  1YXE A;  1A0H A;  1URK A;  1I8N A;  5EOD A;  4CIK A;  5HPG A;  2KJ4 A;  2DOH X;  4BV5 A;  2Y8R A;  1BHT A;  2KNF A;  5COE A;  4NZQ A;  2PF1 A;  3K65 A;  1W8K A;  4IUA A;  2YIP A;  5CS5 A;  3SRJ A;  1NL2 A;  5CSQ A;  2J8J A;  2PK4 A;  1PK2 A;  5CP9 A;  4R1C A;  2K13 X;  3BT2 A;  2FEB A;  4Z0D A;  2I9A A;  3ZLE A;  2FD6 A;  1HPK A; 
#chains in the Genus database with same CATH topology
 3SRI A;  4UV6 A;  5CS9 A;  3KIV A;  4R19 A;  1PKR A;  1HPJ A;  2HGF A;  3U73 A;  4APL A;  2F83 A;  2HPQ P;  2K4R A;  4YIV A;  2Q8B A;  3SP8 A;  4BVD A;  1PK4 A;  1B2I A;  2X2Z A;  4BV7 A;  4BVC A;  1CEB A;  2Q8A A;  3HMR A;  3E6P L;  1PMK A;  4YIZ A;  4Z09 A;  5CT1 A;  2YIO A;  2I9B A;  4Z0E A;  1GMN A;  3HN4 A;  5I25 A;  1KI0 A;  4BVV A;  4BVW A;  1KDU A;  2QJ2 A;  2YIL A;  2K51 A;  2SPT A;  5CT2 A;  5EOK A;  5CS3 A;  2DOI A;  4Z0F A;  1Z40 A;  2LL3 A;  1W81 A;  1I5K A;  3LAQ A;  2Z8W A;  1GP9 A;  1I71 A;  4D3C A;  4O03 A;  3BT1 A;  1NK1 A;  4KIV A;  4UAO A;  5CS1 A;  2HPP P;  1CEA A;  1GMO A;  1HKY A;  4A5T S;  1NL1 A;  2J8L A;  1TPK A;  2L0S A;  1PML A;  3ZWZ A;  4HZH A;  3HMS A;  2LL4 M;  4R1A A;  4R1B A;  3MKP A;  2PF2 A;  3HMT A;  2QJ4 A;  2Z8V A;  3NXP A;  1JFN A;  5CT3 A;  4DUR A;  4APM A;  1KRN A;  1KIV A;  1YXE A;  1A0H A;  1URK A;  1I8N A;  5EOD A;  4CIK A;  5HPG A;  2KJ4 A;  2DOH X;  4BV5 A;  2Y8R A;  1BHT A;  2KNF A;  5COE A;  4NZQ A;  2PF1 A;  3K65 A;  1W8K A;  2KL5 A;  4IUA A;  2YIP A;  5CS5 A;  3SRJ A;  1NL2 A;  5CSQ A;  2J8J A;  2PK4 A;  1PK2 A;  5CP9 A;  4R1C A;  2K13 X;  3BT2 A;  2FEB A;  4Z0D A;  2I9A A;  3ZLE A;  2FD6 A;  1HPK A; 
#chains in the Genus database with same CATH homology
 3SRI A;  4UV6 A;  5CS9 A;  3KIV A;  4R19 A;  1PKR A;  1HPJ A;  2HGF A;  3U73 A;  4APL A;  2F83 A;  2HPQ P;  2K4R A;  4YIV A;  2Q8B A;  3SP8 A;  4BVD A;  1PK4 A;  1B2I A;  2X2Z A;  4BV7 A;  4BVC A;  1CEB A;  2Q8A A;  3HMR A;  3E6P L;  1PMK A;  4YIZ A;  4Z09 A;  5CT1 A;  2YIO A;  2I9B A;  4Z0E A;  1GMN A;  3HN4 A;  5I25 A;  1KI0 A;  4BVV A;  4BVW A;  1KDU A;  2QJ2 A;  2YIL A;  2K51 A;  2SPT A;  5CT2 A;  5EOK A;  5CS3 A;  2DOI A;  4Z0F A;  1Z40 A;  2LL3 A;  1W81 A;  1I5K A;  3LAQ A;  2Z8W A;  1GP9 A;  1I71 A;  4D3C A;  4O03 A;  3BT1 A;  1NK1 A;  4KIV A;  4UAO A;  5CS1 A;  2HPP P;  1CEA A;  1GMO A;  1HKY A;  4A5T S;  1NL1 A;  2J8L A;  1TPK A;  2L0S A;  1PML A;  3ZWZ A;  4HZH A;  3HMS A;  2LL4 M;  4R1A A;  4R1B A;  3MKP A;  2PF2 A;  3HMT A;  2QJ4 A;  2Z8V A;  3NXP A;  1JFN A;  5CT3 A;  4DUR A;  4APM A;  1KRN A;  1KIV A;  1YXE A;  1A0H A;  1URK A;  1I8N A;  5EOD A;  4CIK A;  5HPG A;  2KJ4 A;  2DOH X;  4BV5 A;  2Y8R A;  1BHT A;  2KNF A;  5COE A;  4NZQ A;  2PF1 A;  3K65 A;  1W8K A;  2KL5 A;  4IUA A;  2YIP A;  5CS5 A;  3SRJ A;  1NL2 A;  5CSQ A;  2J8J A;  2PK4 A;  1PK2 A;  5CP9 A;  4R1C A;  2K13 X;  3BT2 A;  2FEB A;  4Z0D A;  2I9A A;  3ZLE A;  2FD6 A;  1HPK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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